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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of B cell activation
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Accession:GO:0050864 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: regulation of B lymphocyte activation


show annotations for term's descendants           Sort by:
regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in IEA GO_REF:0000117 UniProt GO_REF:0000117 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Cd19 CD19 molecule involved_in ISO
IEA 		(PMID:1373518)
GO_REF:0000107
GO_REF:0000002 		RGD
Ensembl
InterPro		 PMID:1373518 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:190,417,853...190,424,494
Ensembl chr 1:190,417,853...190,424,355 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3759678 (PMID:16129705) 		Ensembl
RGD		 PMID:16129705 GO_REF:0000107 NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:78,382,855...78,406,201 		JBrowse link
G Themis2 thymocyte selection associated family member 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:24907343) 		Ensembl
RGD		 PMID:24907343 GO_REF:0000107 NCBI chr 5:150,275,094...150,290,343
Ensembl chr 5:150,275,094...150,290,343 		JBrowse link
G Tlr9 toll-like receptor 9 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1922072 (PMID:23109291) 		Ensembl
RGD		 PMID:23109291 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
B cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd320 CD320 molecule involved_in ISO
ISS 		(PMID:10727470)
GO_REF:0000024 		RGD
UniProt		 PMID:10727470 GO_REF:0000024 NCBI chr 7:15,328,320...15,334,138
Ensembl chr 7:15,311,286...15,334,138 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15240667) 		GO_Central
RGD		 PMID:15240667 GO_REF:0000033 NCBI chr 7:115,616,139...115,618,647
Ensembl chr 7:115,616,303...115,618,620 		JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:15240667) 		Ensembl
RGD		 PMID:15240667 GO_REF:0000107 NCBI chr16:86,164,377...86,195,072
Ensembl chr16:86,164,377...86,194,499 		JBrowse link
negative regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bank1 B-cell scaffold protein with ankyrin repeats 1 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:88336 (PMID:16546095)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:16546095 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:227,203,998...227,474,008
Ensembl chr 2:227,203,998...227,474,037 		JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:25545336 RGD:151665128 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334 (PMID:6610701) RGD PMID:6610701 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:241,205,935...241,246,104 		JBrowse link
G Foxj1 forkhead box J1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16002694) 		Ensembl
RGD		 PMID:16002694 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:102,065,170...102,069,241 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2386884 (PMID:10704460) 		Ensembl
RGD		 PMID:10704460 GO_REF:0000107 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:20519653) RGD PMID:20519653 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:148,339,435...148,393,927 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO (PMID:24803541) RGD PMID:24803541 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:96,169,028...96,169,107 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 involved_in IBA
ISO
IEA 		GO_REF:0000033
(PMID:19923443)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:19923443 GO_REF:0000033 GO_REF:0000107 NCBI chr11:27,971,565...28,021,944
Ensembl chr11:27,970,564...28,021,944 		JBrowse link
G Tbc1d10c TBC1 domain family, member 10C acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1932389|MGI:5578034 (PMID:23109291) 		Ensembl
RGD		 PMID:23109291 GO_REF:0000107 NCBI chr 1:210,906,621...210,913,649
Ensembl chr 1:210,906,616...210,994,356 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:21088135) 		Ensembl
RGD		 PMID:21088135 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:15,528,921...15,543,979 		JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) RGD PMID:16618805 NCBI chr12:12,660,035...12,735,584
Ensembl chr12:12,659,946...12,735,581 		JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) RGD PMID:12714519 NCBI chr  X:154,341,106...154,346,087
Ensembl chr  X:154,340,935...154,346,097 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (PMID:18523151) RGD PMID:18523151 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:47,457,554...47,472,961 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA 		(PMID:18941195)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:18941195 GO_REF:0000107 GO_REF:0000117 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:75,278,325...75,316,736 		JBrowse link
negative regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:62,727,291...62,828,629 		JBrowse link
G Btk Bruton tyrosine kinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856317 (PMID:7680896) 		Ensembl
RGD		 PMID:7680896 GO_REF:0000107 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (PMID:12796776) RGD PMID:12796776 NCBI chr11:69,069,734...69,099,331
Ensembl chr11:69,052,644...69,093,224 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2178778 (PMID:12970760) 		Ensembl
RGD		 PMID:12970760 GO_REF:0000107 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732 		JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:21482706) RGD PMID:21482706 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:100,428,826...100,442,958 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:109,100,772...109,119,248 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:69,813,265...69,819,973 		JBrowse link
G Il10 interleukin 10 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:9184696) 		UniProt
Ensembl
RGD		 PMID:9184696 GO_REF:0000024 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2386884 (PMID:10704460) 		Ensembl
RGD		 PMID:10704460 GO_REF:0000107 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO 		GO_REF:0000107
(PMID:9252121) 		Ensembl
RGD		 PMID:9252121 GO_REF:0000107 NCBI chr 5:21,437,127...21,553,097
Ensembl chr 5:21,437,084...21,554,461 		JBrowse link
G Mir185 microRNA 185 acts_upstream_of ISO (PMID:24803541) RGD PMID:24803541 NCBI chr11:96,169,028...96,169,107
Ensembl chr11:96,169,028...96,169,107 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr13:88,550,224...88,567,892
Ensembl chr13:88,550,228...88,566,537 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (PMID:12970181) RGD PMID:12970181 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:45,531,637...45,611,492 		JBrowse link
G Pkn1 protein kinase N1 acts_upstream_of_or_within ISO MGI:5475202 (PMID:23223530) RGD PMID:23223530 NCBI chr19:41,346,855...41,374,832
Ensembl chr19:41,346,860...41,378,395 		JBrowse link
G Prdm1 PR/SET domain 1 acts_upstream_of_or_within ISO (PMID:18845144) RGD PMID:18845144 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18172933) 		Ensembl
RGD		 PMID:18172933 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:75,707,338...75,772,816 		JBrowse link
G Tnfrsf13b TNF receptor superfamily member 13B acts_upstream_of_or_within ISO MGI:3052983 (PMID:15240667) RGD PMID:15240667 NCBI chr10:46,301,336...46,322,460
Ensembl chr10:46,301,316...46,324,408 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
ISO
IEA
IBA 		GO_REF:0000024
(PMID:12515813)
GO_REF:0000107
GO_REF:0000033 		UniProt
RGD
Ensembl
GO_Central		 PMID:12515813 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:25,376,400...25,451,323 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in ISO
IEA
IBA 		(PMID:21727189)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033 		RGD
UniProt
Ensembl
GO_Central		 PMID:21727189 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:94,800,117...94,804,299 		JBrowse link
negative regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Parp3 poly (ADP-ribose) polymerase family, member 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26000965) 		Ensembl
RGD		 PMID:26000965 GO_REF:0000107 NCBI chr 8:115,989,721...115,995,822
Ensembl chr 8:115,987,176...115,995,472 		JBrowse link
negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103034|MGI:2158438 (PMID:10490661) 		Ensembl
RGD		 PMID:10490661 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3696705 (PMID:16275384) 		Ensembl
RGD		 PMID:16275384 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3695433 (PMID:17137798) 		Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
positive regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 involved_in ISO (PMID:26041538) RGD PMID:26041538 NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:53,904,285...53,918,934 		JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO 		GO_REF:0000024
(PMID:23499492) 		UniProt
RGD		 PMID:23499492 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:16129705), (PMID:8566034), (PMID:9798653) RGD PMID:8566034 PMID:9798653 PMID:16129705 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322) RGD PMID:3491322 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO
IEA 		(PMID:20844241)
GO_REF:0000107 		RGD
Ensembl		 PMID:20844241 GO_REF:0000107 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:34,555,832...34,722,846 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4361448 (PMID:19734906) 		Ensembl
RGD		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466 		JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:29636373) 		Ensembl
RGD		 PMID:29636373 GO_REF:0000107 NCBI chr  X:38,686,530...39,031,658
Ensembl chr  X:38,686,530...39,031,393 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3029019 (PMID:12855817) RGD PMID:12855817 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:23857366)
GO_REF:0000107 		RGD
Ensembl		 PMID:23857366 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9670042) 		Ensembl
RGD		 PMID:9670042 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:16633345) 		Ensembl
RGD		 PMID:16633345 GO_REF:0000107 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:80,452,845...80,470,992 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in IEA
ISO 		GO_REF:0000107
(PMID:21423173) 		Ensembl
RGD		 PMID:21423173 GO_REF:0000107 NCBI chr  X:143,600,763...143,788,407
Ensembl chr  X:143,600,767...143,788,432 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:3029528 (PMID:12431371) RGD PMID:12431371 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Cd27 CD27 molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2429736 (PMID:9252128) 		Ensembl
RGD		 PMID:9252128 GO_REF:0000107 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:16797412) RGD PMID:16797412 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:2386884 (PMID:10704460), (PMID:9620849)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:9620849 PMID:10704460 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:95,735,530...95,840,589 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:21572390)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:21572390 GO_REF:0000024 GO_REF:0000107 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:31,857,546...31,869,893 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO 		GO_REF:0000024
(PMID:19015308) 		UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947) RGD PMID:20870947 NCBI chr16:83,125,386...83,150,851
Ensembl chr16:83,124,658...83,156,970 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:3759678 (PMID:16129705)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:16129705 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:78,382,855...78,406,201 		JBrowse link
G Prdm1 PR/SET domain 1 acts_upstream_of_or_within ISO (PMID:18845144) RGD PMID:18845144 NCBI chr20:49,542,465...49,564,088
Ensembl chr20:49,542,465...49,564,088 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA
ISS 		(PMID:33951726)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:33951726 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:97,527,572...97,549,540 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103035 (PMID:10979977) 		Ensembl
RGD		 PMID:10979977 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103036 (PMID:10979977) 		Ensembl
RGD		 PMID:10979977 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:18369315)
MGI:1857421 (PMID:7477353)
MGI:2384078 (PMID:7477352)
GO_REF:0000107 		RGD
Ensembl		 PMID:7477352 PMID:7477353 PMID:18369315 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
ISS 		(PMID:11460154)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
positive regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964) 		Ensembl
RGD		 PMID:14607964 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4127920 (PMID:25404367) 		Ensembl
RGD		 PMID:25404367 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2158437 (PMID:9171827) 		Ensembl
RGD		 PMID:9171827 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in IEA
ISO 		GO_REF:0000107
(PMID:15964995) 		Ensembl
RGD		 PMID:15964995 GO_REF:0000107 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:86,243,491...86,250,024 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:71,466,179...71,482,671
Ensembl chr14:71,466,180...71,482,647 		JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:102,016,074...102,055,143 		JBrowse link
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3039682 (PMID:12867038) 		Ensembl
RGD		 PMID:12867038 GO_REF:0000107 NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045 		JBrowse link
G Cd320 CD320 molecule involved_in ISO
ISS 		(PMID:10727470)
GO_REF:0000024 		RGD
UniProt		 PMID:10727470 GO_REF:0000024 NCBI chr 7:15,328,320...15,334,138
Ensembl chr 7:15,311,286...15,334,138 		JBrowse link
G Cd38 CD38 molecule involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:17875758)
(PMID:8666928)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:8666928 PMID:17875758 GO_REF:0000033 GO_REF:0000107 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:71,384,532...71,424,505 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO MGI:87891 (PMID:10979977), (PMID:11894097), (PMID:14607964), (PMID:15963492), (PMID:8666928), (PMID:8920854) RGD PMID:8666928 PMID:8920854 PMID:10979977 PMID:11894097 PMID:14607964 More... NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Cd40lg CD40 ligand IDA RGD PMID:18384807 RGD:2313415 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:140,164,302...140,176,475 		JBrowse link
G Cd74 CD74 molecule involved_in ISO (PMID:12782713) RGD PMID:12782713 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO (PMID:10400713) RGD PMID:10400713 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:207,664,885...207,681,092 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:107739 (PMID:12970760) RGD PMID:12970760 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:88336 (PMID:15963492) RGD PMID:15963492 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:177,479,091...177,491,326 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in IBA
ISO 		GO_REF:0000033
(PMID:12023368) 		GO_Central
RGD		 PMID:12023368 GO_REF:0000033 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO
IEA 		(PMID:24803541)
GO_REF:0000107 		RGD
Ensembl		 PMID:24803541 GO_REF:0000107 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:154,179,065...154,360,615 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO 		GO_REF:0000024
(PMID:21673108) 		UniProt
RGD		 PMID:21673108 GO_REF:0000024 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:105,437,561...105,466,977 		JBrowse link
G Il13 interleukin 13 IDA requires CD40 antigen RGD PMID:11573960 PMID:10331006 RGD:633067, RGD:61509 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:38,290,926...38,293,483 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IDA requires CD40 antigen RGD PMID:11573960 RGD:633067 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:120,214,075...120,274,461 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO
IEA 		(PMID:9184696)
GO_REF:0000107 		RGD
Ensembl		 PMID:9184696 GO_REF:0000107 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO
IEA 		(PMID:17673207)
GO_REF:0000107 		RGD
Ensembl		 PMID:17673207 GO_REF:0000107 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:122,045,240...122,055,142 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10979977), (PMID:14607964) RGD PMID:10979977 PMID:14607964 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il5 interleukin 5 IDA RGD PMID:10529595 RGD:2303750 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:38,375,132...38,378,003 		JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
MGI:87859 (PMID:12970760), (PMID:7671324) 		UniProt
RGD		 PMID:7671324 PMID:12970760 GO_REF:0000024 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15572028) 		Ensembl
RGD		 PMID:15572028 GO_REF:0000107 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO 		GO_REF:0000024
(PMID:18955699) 		UniProt
RGD		 PMID:18955699 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:15,708,924...15,871,640 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:12782713) RGD PMID:12782713 NCBI chr20:12,767,138...12,791,222
Ensembl chr 4:134,041,774...134,042,121
Ensembl chr20:134,041,774...134,042,121 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO
ISS 		(PMID:17875758)
GO_REF:0000024 		RGD
UniProt		 PMID:17875758 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:177,618,314...177,747,380 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4361448 (PMID:19734906) 		Ensembl
RGD		 PMID:19734906 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:99,455,811...99,510,466 		JBrowse link
G Prlr prolactin receptor IMP RGD PMID:8650199 PMID:9447986 RGD:151665811, RGD:151667430 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:60,861,658...61,051,882 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:1793833)
MGI:1857277|MGI:2181288 (PMID:8566034), (PMID:8666928), (PMID:9015183), (PMID:9254656)
GO_REF:0000107 		RGD
Ensembl		 PMID:1793833 PMID:8566034 PMID:8666928 PMID:9015183 PMID:9254656 GO_REF:0000107 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within 		IBA
ISO
IEA 		GO_REF:0000033
MGI:3716944 (PMID:16227612)
GO_REF:0000107 		GO_Central
RGD
Ensembl		 PMID:16227612 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:132,204,717...132,219,421
Ensembl chr  X:132,204,543...132,219,419 		JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:5642299 (PMID:25074919) 		Ensembl
RGD		 PMID:25074919 GO_REF:0000107 NCBI chr 9:62,331,281...62,454,754
Ensembl chr 9:62,370,598...62,454,747 		JBrowse link
G Tcf3 transcription factor 3 involved_in ISO
ISS 		(PMID:11509675)
GO_REF:0000024 		RGD
UniProt		 PMID:11509675 GO_REF:0000024 NCBI chr 7:9,931,251...9,952,994
Ensembl chr 7:9,928,685...9,953,044 		JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO 		GO_REF:0000024
(PMID:26642240) 		UniProt
RGD		 PMID:26642240 GO_REF:0000024 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3029019 (PMID:12855817) RGD PMID:12855817 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,172,963...1,196,892 		JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:12447442) RGD PMID:12447442 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:41,791,878...41,796,312 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1860885 (PMID:10549626) 		Ensembl
RGD		 PMID:10549626 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:85,161,192...85,175,007 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:23857366)
GO_REF:0000107 		RGD
Ensembl		 PMID:23857366 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C involved_in
acts_upstream_of_or_within 		IBA
ISO 		GO_REF:0000033
(PMID:15240667) 		GO_Central
RGD		 PMID:15240667 GO_REF:0000033 NCBI chr 7:115,616,139...115,618,647
Ensembl chr 7:115,616,303...115,618,620 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:7749983) RGD PMID:7749983 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:171,889,117...171,892,616 		JBrowse link
G Tnfsf13 TNF superfamily member 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815 		JBrowse link
G Tnfsf13b TNF superfamily member 13b involved_in
acts_upstream_of_or_within 		ISO
IEA
IBA 		(PMID:17499850)
(PMID:15240667)
GO_REF:0000107
GO_REF:0000033 		RGD
Ensembl
GO_Central		 PMID:15240667 PMID:17499850 GO_REF:0000033 GO_REF:0000107 NCBI chr16:86,164,377...86,195,072
Ensembl chr16:86,164,377...86,194,499 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:7749983) 		Ensembl
RGD		 PMID:7749983 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO
IEA 		(PMID:17875758)
GO_REF:0000107 		RGD
Ensembl		 PMID:17875758 GO_REF:0000107 NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:199,700,445...200,042,343 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:10933391) 		Ensembl
RGD		 PMID:10933391 GO_REF:0000107 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,533,734...44,577,919 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12496423) 		Ensembl
RGD		 PMID:12496423 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr 5:64,369,495...64,374,711
Ensembl chr 5:64,369,495...64,374,902 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21255825) 		Ensembl
RGD		 PMID:21255825 GO_REF:0000107 NCBI chr19:55,931,523...55,932,937
Ensembl chr19:55,931,523...55,932,937 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:31806351)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:31806351 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:121,950,129...121,972,937
Ensembl chr 4:121,950,840...121,972,891 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28114273)
GO_REF:0000117
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28114273 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:210,429,672...210,479,042
Ensembl chr 1:210,430,127...210,479,035 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28114273)
GO_REF:0000117
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28114273 GO_REF:0000024 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:78,128,325...78,135,931
Ensembl chr 1:78,128,325...78,135,931 		JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:163,846,687...163,859,851 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) RGD PMID:20671152 NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23306439), (PMID:23333305), (PMID:23333306) 		Ensembl
RGD		 PMID:23306439 PMID:23333305 PMID:23333306 GO_REF:0000107 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:56,963,854...57,017,106 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA 		(PMID:29656893)
GO_REF:0000033 		RGD
GO_Central		 PMID:29656893 GO_REF:0000033 NCBI chr 3:140,391,611...140,462,273
Ensembl chr 3:140,389,220...140,462,609 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,554,921...9,646,186
Ensembl chr16:9,553,854...9,588,510 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 2:37,031,045...37,035,859
Ensembl chr 2:37,031,045...37,032,328 		JBrowse link
G Tfrc transferrin receptor involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:26642240) 		UniProt
Ensembl
RGD		 PMID:26642240 GO_REF:0000024 GO_REF:0000107 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:81,668,478...81,690,318 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO
IEA 		(PMID:23345425), (PMID:23760478)
(PMID:15077110), (PMID:15159415)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:128,620,322...128,696,747 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23241889) 		Ensembl
RGD		 PMID:23241889 GO_REF:0000107 NCBI chr14:81,057,727...81,135,866
Ensembl chr14:81,057,727...81,123,027 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q9JK91 (PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within 		ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:14988498) 		AgBase
Ensembl
RGD		 PMID:14988498 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in 		ISO
IEA
IBA 		(PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000117
GO_REF:0000033 		RGD
UniProt
GO_Central		 PMID:14988498 GO_REF:0000033 GO_REF:0000117 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,898,805...54,901,815 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (PMID:12023368) RGD PMID:12023368 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:210,937,255...210,947,064 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:65,365,306...65,383,795 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4127920 (PMID:25404367) 		Ensembl
RGD		 PMID:25404367 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,568,591...65,616,376 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:7688139) RGD PMID:7688139 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:69,545,326...69,689,192 		JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:174,209,719...174,224,847 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:1830926) RGD PMID:1830926 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) RGD PMID:12882831 PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:120,065,900...120,112,011 		JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:12,567,368...12,626,503 		JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 1:191,053,228...191,055,554 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 4:8,258,930...8,310,490
Ensembl chr 4:8,258,952...8,310,488 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in IEA
ISO 		GO_REF:0000107
UniProtKB:Q9JK91 (PMID:10430621) 		Ensembl
RGD		 PMID:10430621 GO_REF:0000107 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:15,790,478...15,815,248 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9015183) RGD PMID:9015183 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2180194 (PMID:12882831) 		Ensembl
RGD		 PMID:12882831 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,578,751...82,595,253 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:30842412) 		Ensembl
RGD		 PMID:30842412 GO_REF:0000107 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:138,315,282...138,335,766 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO
IEA 		UniProtKB:P60568 (PMID:22962438)
GO_REF:0000107 		RGD
Ensembl		 PMID:22962438 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:45,025,087...45,029,580 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO
IEA 		UniProtKB:P22301 (PMID:22962438)
GO_REF:0000107 		RGD
Ensembl		 PMID:22962438 GO_REF:0000107 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
ISS 		(PMID:11460154)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) RGD PMID:27010503 NCBI chr16:18,109,865...18,116,999
Ensembl chr16:18,110,476...18,114,244 		JBrowse link
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3039682 (PMID:12867038) 		Ensembl
RGD		 PMID:12867038 GO_REF:0000107 NCBI chr12:18,735,088...18,872,045
Ensembl chr12:18,735,088...18,872,045 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3664438 (PMID:16501569) 		Ensembl
RGD		 PMID:16501569 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9806640) 		Ensembl
RGD		 PMID:9806640 GO_REF:0000107 NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:29288206) RGD PMID:29288206 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:104,435,981...104,461,053 		JBrowse link
G Mir150 microRNA 150 acts_upstream_of_or_within ISO MGI:3763431 (PMID:17927961) RGD PMID:17927961 NCBI chr 1:104,741,487...104,741,571
Ensembl chr 1:104,741,487...104,741,571 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		GO_REF:0000002
(PMID:15143214) 		InterPro
RGD		 PMID:15143214 GO_REF:0000002 NCBI chr 7:116,019,383...116,055,628
Ensembl chr 7:116,020,311...116,055,378 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856074 (PMID:9254656) 		Ensembl
RGD		 PMID:9254656 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:159,212,320...159,237,069 		JBrowse link
G Slamf8 SLAM family member 8 involved_in ISO (PMID:11313408) RGD PMID:11313408 NCBI chr13:87,580,081...87,589,941
Ensembl chr13:87,580,182...87,589,560 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO
IEA 		(PMID:23857366)
GO_REF:0000107 		RGD
Ensembl		 PMID:23857366 GO_REF:0000107 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:115,742,889...115,750,148 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:27102483) 		UniProt
RGD		 PMID:27102483 GO_REF:0000024 NCBI chr 6:104,663,396...104,669,815
Ensembl chr 6:104,663,399...104,687,979 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:27102483) 		Ensembl
RGD		 PMID:27102483 GO_REF:0000107 NCBI chr 6:16,242,622...16,246,662
Ensembl chr 6:16,242,610...16,246,653 		JBrowse link
regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO (PMID:15681594) RGD PMID:15681594 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:57,961,423...57,998,901 		JBrowse link
G Cd22 CD22 molecule involved_in IBA
ISO 		GO_REF:0000033
UniProtKB:Q80ZE3 (PMID:20200274) 		GO_Central
RGD		 PMID:20200274 GO_REF:0000033 NCBI chr 1:95,243,785...95,270,430
Ensembl chr 1:95,244,868...95,259,730 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:9806640) 		Ensembl
RGD		 PMID:9806640 GO_REF:0000107 NCBI chr10:83,956,850...84,049,861
Ensembl chr10:83,962,030...84,049,861 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein involved_in ISS
ISO
IEA
IBA 		GO_REF:0000024
(PMID:21093319)
GO_REF:0000107
GO_REF:0000033 		UniProt
RGD
Ensembl
GO_Central		 PMID:21093319 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:27,513,087...27,515,148
Ensembl chr18:27,513,089...27,515,182 		JBrowse link
G Siglec10 sialic acid binding Ig-like lectin 10 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:102,953,894...102,962,964
Ensembl chr 1:102,953,918...102,962,964 		JBrowse link
regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplf aprataxin and PNKP like factor acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:4128102 (PMID:21211721) 		Ensembl
RGD		 PMID:21211721 GO_REF:0000107 NCBI chr 4:121,627,800...121,679,980
Ensembl chr 4:121,627,800...121,679,961 		JBrowse link
G Mir181b1 microRNA 181b-1 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr13:52,037,228...52,037,337
Ensembl chr13:52,037,228...52,037,337 		JBrowse link
G Mir181b2 microRNA 181b-2 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr 3:43,026,666...43,026,753
Ensembl chr 3:43,026,666...43,026,753 		JBrowse link
G Supt6h SPT6 homolog, histone chaperone and transcription elongation factor involved_in IEA
ISO 		GO_REF:0000107
(PMID:21518874) 		Ensembl
RGD		 PMID:21518874 GO_REF:0000107 NCBI chr10:63,601,990...63,638,851
Ensembl chr10:63,601,993...63,638,851 		JBrowse link
regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3696705 (PMID:16275384) 		Ensembl
RGD		 PMID:16275384 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Il27ra interleukin 27 receptor subunit alpha acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3525439 (PMID:11057672) 		Ensembl
RGD		 PMID:11057672 GO_REF:0000107 NCBI chr19:41,014,730...41,026,740
Ensembl chr19:41,014,730...41,026,760 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3695433 (PMID:17137798) 		Ensembl
RGD		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,516,981...30,568,471 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:25310967)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:25310967 GO_REF:0000024 GO_REF:0000107 NCBI chr12:34,684,583...34,718,429
Ensembl chr12:34,698,955...34,719,819 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      regulation of immune system process 1719
        regulation of leukocyte activation 607
          regulation of lymphocyte activation 523
            regulation of B cell activation 143
              negative regulation of B cell activation + 34
              positive regulation of B cell activation + 92
              regulation of B cell differentiation + 36
              regulation of B cell proliferation + 72
              regulation of isotype switching + 41
Path 2
Term Annotations click to browse term
  biological_process 19315
    biological regulation 13355
      regulation of biological process 12936
        regulation of cellular process 12518
          regulation of cell activation 666
            regulation of leukocyte activation 607
              regulation of lymphocyte activation 523
                regulation of B cell activation 143
                  negative regulation of B cell activation + 34
                  positive regulation of B cell activation + 92
                  regulation of B cell differentiation + 36
                  regulation of B cell proliferation + 72
                  regulation of isotype switching + 41
paths to the root