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ONTOLOGY REPORT - ANNOTATIONS

Term:pyruvate transmembrane transporter activity
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Accession:GO:0050833 term browser browse the term
Definition:Enables the transfer of pyruvate, 2-oxopropanoate, from one side of a membrane to the other.
Synonyms:related_synonym: monocarboxylate (lactate, pyruvate, mevalonate) uptake/efflux porter activity
 xref: Reactome:R-HSA-372342 "MPC1:MPC2 imports PYR, H+ to mitochondrial matrix"


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pyruvate transmembrane transporter activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpc1 mitochondrial pyruvate carrier 1 enables
contributes_to		 IBA
ISO		 GO_REF:0000033
MGI:1917706 (PMID:22628554)		 GO_Central
RGD		 PMID:22628554 GO_REF:0000033 NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 enables
contributes_to		 IBA
ISO		 GO_REF:0000033
MGI:1915240 (PMID:22628554)		 GO_Central
RGD		 PMID:22628554 GO_REF:0000033 NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664 		JBrowse link
G Slc16a11 solute carrier family 16, member 11 enables ISO (PMID:28666119) RGD PMID:28666119 NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915 		JBrowse link
G Slc16a3 solute carrier family 16 member 3 enables ISO
ISS
IEA		 (PMID:31719150)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:31719150 GO_REF:0000024 GO_REF:0000107 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562 		JBrowse link
G Slc16a7 solute carrier family 16 member 7 enables ISS
ISO		 GO_REF:0000024
(PMID:32415067), (PMID:9786900)		 UniProt
RGD		 PMID:9786900 PMID:32415067 GO_REF:0000024 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  molecular_function 21086
    transporter activity 1269
      transmembrane transporter activity 1162
        organic anion transmembrane transporter activity 281
          carboxylic acid transmembrane transporter activity 192
            monocarboxylic acid transmembrane transporter activity 71
              pyruvate transmembrane transporter activity 5
                pyruvate secondary active transmembrane transporter activity 0
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