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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of immune response
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Accession:GO:0050778 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
Synonyms:exact_synonym: up regulation of immune response;   upregulation of immune response
 narrow_synonym: stimulation of immune response



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positive regulation of immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:129,549,236...129,555,354 JBrowse link
G Ctsg cathepsin G acts_upstream_of_or_within ISO MGI:2182170|MGI:2679229 (PMID:10714686) RGD PMID:10714686 NCBI chr15:33,901,230...33,907,596 JBrowse link
G Elane elastase, neutrophil expressed acts_upstream_of_or_within ISO MGI:2182177|MGI:88563 (PMID:10714686) RGD PMID:10714686 NCBI chr 7:10,467,877...10,469,725 JBrowse link
G ENSRNOG00000070540 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Fcer1g Fc epsilon receptor Ig acts_upstream_of_or_within ISO MGI:1857165 (PMID:10395649) RGD PMID:10395649 NCBI chr13:83,649,447...83,654,248 JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (PMID:30675063) RGD PMID:30675063 NCBI chr 1:52,926,953...52,927,912 JBrowse link
G Ifnl1 interferon, lambda 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:83,798,651...83,800,297 JBrowse link
G Ifnl3 interferon, lambda 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:83,814,456...83,816,096 JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ighg1 immunoglobulin heavy constant gamma 1 acts_upstream_of_or_within ISO (PMID:10395649) RGD PMID:10395649
G Il15 interleukin 15 involved_in
acts_upstream_of_or_within
IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
MGI:2136897 (PMID:10704459)
Ensembl
GO_Central
RGD
PMID:10704459 GO_REF:0000033 GO_REF:0000107 NCBI chr19:25,640,025...25,706,818 JBrowse link
G Mif macrophage migration inhibitory factor IMP RGD PMID:10617911 RGD:1642013 NCBI chr20:12,767,138...12,791,222 JBrowse link
G Mir136 microRNA 136 involved_in ISO (PMID:26450567) RGD PMID:26450567 NCBI chr 6:128,549,096...128,549,177 JBrowse link
G Pla2g1b phospholipase A2 group IB involved_in ISO (PMID:16005851) RGD PMID:16005851 NCBI chr12:46,802,932...46,814,511 JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:48,774,985...48,788,245 JBrowse link
G RT1-B RT1 class II, locus B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G RT1-Ba RT1 class II, locus Ba involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,575,134...4,579,727 JBrowse link
G RT1-Bb RT1 class II, locus Bb involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,596,558...4,602,201 JBrowse link
G RT1-Da RT1 class II, locus Da acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:95921 (PMID:11714799)
GO_REF:0000033
RGD
GO_Central
PMID:11714799 GO_REF:0000033 NCBI chr20:4,515,393...4,520,387 JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,548,664...4,558,237 JBrowse link
G RT1-Db2 RT1 class II, locus Db2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,520,723...4,539,724 JBrowse link
G RT1-DMa RT1 class II, locus DMa acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2652160 (PMID:11714799)
GO_REF:0000033
RGD
GO_Central
PMID:11714799 GO_REF:0000033 NCBI chr20:4,708,932...4,712,335 JBrowse link
G RT1-DMb RT1 class II, locus DMb involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,693,102...4,700,340 JBrowse link
G RT1-DOb RT1 class II, locus DOb involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,619,418...4,625,627 JBrowse link
G RT1-Ha RT1 class II, locus Ha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,762,425...4,772,439 JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:4,777,494...4,781,486 JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO
ISS
(PMID:8133057)
GO_REF:0000024
RGD
UniProt
PMID:8133057 GO_REF:0000024 NCBI chr13:98,160,075...98,261,771 JBrowse link
activation of immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Trex1 three prime repair exonuclease 1 acts_upstream_of_or_within ISO (PMID:18045533) RGD PMID:18045533 NCBI chr 8:109,706,613...109,707,913 JBrowse link
activation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aim2 absent in melanoma 2 involved_in ISO
IBA
(PMID:19158675), (PMID:19158676), (PMID:19158679)
(PMID:19158676)
GO_REF:0000033
RGD
GO_Central
PMID:19158675 PMID:19158676 PMID:19158679 GO_REF:0000033 NCBI chr13:85,865,206...85,906,996 JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS
(PMID:32298652)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:32298652 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:221,140,287...221,152,727 JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IBA
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:26046437), (PMID:28363908), (PMID:29426904), (PMID:30007416), (PMID:32817552), (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35438208)
(PMID:23258413), (PMID:23929945), (PMID:24077100), (PMID:29426904), (PMID:32911480), (PMID:32911481), (PMID:32913000)
GO_REF:0000033
RGD
GO_Central
PMID:23258413 PMID:23929945 PMID:24077100 PMID:26046437 PMID:28363908 More... GO_REF:0000033 NCBI chr 8:79,292,282...79,306,998 JBrowse link
G ENSRNOG00000069878 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24739961) RGD PMID:24739961 NCBI chr 2:234,071,366...234,106,012 JBrowse link
G Gbp2 guanylate binding protein 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:24739961)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:24739961 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:231,332,488...231,348,573 JBrowse link
G Gbp4 guanylate binding protein 4 involved_in ISO (PMID:24739961) RGD PMID:24739961 NCBI chr 2:233,978,163...233,992,124 JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:24739961) RGD PMID:24739961 NCBI chr 2:233,910,999...233,930,320 JBrowse link
G Gbp7 guanylate binding protein 7 involved_in ISO (PMID:24739961) RGD PMID:24739961 NCBI chr 2:233,948,774...233,970,532 JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr10:88,062,808...88,064,920 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:24971542) RGD PMID:24971542 NCBI chr12:11,009,236...11,015,941 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 involved_in ISO
ISS
(PMID:20628368)
GO_REF:0000024
RGD
UniProt
PMID:20628368 GO_REF:0000024 NCBI chr 6:135,523,604...135,529,687 JBrowse link
G Ifi214 interferon activated gene 214 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:85,940,028...85,951,004 JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:45,264,404...45,290,737 JBrowse link
G LOC102556096 pyrin domain-containing protein 3-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:85,911,915...85,929,491 JBrowse link
G Matr3 matrin 3 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr18:27,154,098...27,193,212 JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO
ISS
(PMID:18818105), (PMID:20628368)
GO_REF:0000024
RGD
UniProt
PMID:18818105 PMID:20628368 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094 JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:88,550,224...88,567,892 JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:16648852)
UniProt
RGD
PMID:16648852 GO_REF:0000024 NCBI chr 6:26,743,658...26,771,783 JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 involved_in ISO (PMID:22672233) RGD PMID:22672233 NCBI chr 1:172,357,648...172,365,205 JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:55,778,560...55,833,639 JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:55,838,381...55,904,374 JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr  X:70,594,116...70,611,976 JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISO
ISS
(PMID:26046437)
GO_REF:0000024
RGD
UniProt
PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr11:98,544,952...98,762,499 JBrowse link
G Pspc1 paraspeckle component 1 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr15:30,828,617...30,911,315 JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IBA
(PMID:19158675)
GO_REF:0000033
RGD
GO_Central
PMID:19158675 GO_REF:0000033 NCBI chr 1:192,032,124...192,033,419 JBrowse link
G Rbm14 RNA binding motif protein 14 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 1:202,076,940...202,105,688 JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 5:144,621,678...144,637,930 JBrowse link
G Sin3a SIN3 transcription regulator family member A involved_in ISO (PMID:22783022) RGD PMID:22783022 NCBI chr 8:66,377,471...66,432,150 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IBA
(PMID:18818105), (PMID:23910378)
(PMID:21947006), (PMID:23258412), (PMID:23910378)
GO_REF:0000033
RGD
GO_Central
PMID:18818105 PMID:21947006 PMID:23258412 PMID:23910378 GO_REF:0000033 NCBI chr18:27,332,119...27,338,371 JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:25636800)
GO_REF:0000033
MGI:3046789 (PMID:15661922)
RGD
GO_Central
PMID:15661922 PMID:25636800 GO_REF:0000033 NCBI chr 7:58,963,319...58,996,357 JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within ISO MGI:1860885 (PMID:15661922) RGD PMID:15661922 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:25686612) RGD PMID:25686612 NCBI chr 8:106,864,680...106,868,796 JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:20628368)
Ensembl
UniProt
RGD
PMID:20628368 GO_REF:0000024 GO_REF:0000107 NCBI chr11:43,378,719...43,417,166 JBrowse link
G Trim5 tripartite motif-containing 5 involved_in ISO (PMID:21512573) RGD PMID:21512573 NCBI chr 1:168,132,277...168,149,263 JBrowse link
G Xrcc5 X-ray repair cross complementing 5 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 9:81,404,507...81,493,293 JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:28712728) RGD PMID:28712728 NCBI chr 7:115,423,026...115,443,884 JBrowse link
G Zbp1 Z-DNA binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:32200799), (PMID:32296175), (PMID:32350114), (PMID:33109609)
UniProt
RGD
PMID:32200799 PMID:32296175 PMID:32350114 PMID:33109609 GO_REF:0000024 NCBI chr 3:182,411,665...182,427,604 JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA
(PMID:30135424), (PMID:30193849)
GO_REF:0000033
RGD
GO_Central
PMID:30135424 PMID:30193849 GO_REF:0000033 NCBI chr 3:140,872,460...140,875,292 JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 involved_in ISO (PMID:31685995) RGD PMID:31685995 NCBI chr 3:155,764,073...155,791,777 JBrowse link
activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfh complement factor H acts_upstream_of_or_within ISO (PMID:20813971) RGD PMID:20813971 NCBI chr13:54,063,079...54,164,523 JBrowse link
antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
ISS
(PMID:10587647)
GO_REF:0000024
RGD
UniProt
PMID:10587647 GO_REF:0000024 NCBI chr19:39,679,215...39,713,907 JBrowse link
G Cd19 CD19 molecule involved_in ISO (PMID:1373518) RGD PMID:1373518 NCBI chr 1:180,987,286...180,993,920 JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:3579135 (PMID:15843560)
GO_Central
RGD
PMID:15843560 GO_REF:0000033 NCBI chr13:45,134,825...45,145,381 JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:20,427,057...20,456,845 JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO (PMID:15214043) RGD PMID:15214043 NCBI chr 1:105,076,472...105,081,906 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) RGD PMID:23728777 NCBI chr11:58,251,720...58,279,767 JBrowse link
B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:2153718 (PMID:11120811), (PMID:19228876) RGD PMID:11120811 PMID:19228876 NCBI chr 3:14,979,853...15,083,065 JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member involved_in ISO
IEA
ISS
(PMID:9020138)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:9020138 GO_REF:0000024 GO_REF:0000107 NCBI chr19:39,679,215...39,713,907 JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA
(PMID:17875758)
GO_REF:0000107
RGD
Ensembl
PMID:17875758 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900 JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in ISO UniProtKB:Q8NDB2 (PMID:23555801), (PMID:876631) RGD PMID:876631 PMID:23555801 NCBI chr15:41,802,701...41,841,004 JBrowse link
G Blnk B-cell linker involved_in ISO (PMID:11606584), (PMID:9697839) RGD PMID:9697839 PMID:11606584 NCBI chr 1:239,753,640...239,821,113 JBrowse link
G Bmx BMX non-receptor tyrosine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:30,227,251...30,290,015 JBrowse link
G Btk Bruton tyrosine kinase involved_in ISO
IBA
(PMID:15509800)
GO_REF:0000033
RGD
GO_Central
PMID:15509800 GO_REF:0000033 NCBI chr  X:102,016,070...102,055,448 JBrowse link
G Cd19 CD19 molecule involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:23499492)
(PMID:9254656)
GO_Central
RGD
PMID:9254656 PMID:23499492 GO_REF:0000033 NCBI chr 1:180,987,286...180,993,920 JBrowse link
G Cd38 CD38 molecule involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr14:67,172,062...67,212,328 JBrowse link
G Cd79a CD79a molecule involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:1439759), (PMID:8626447)
(PMID:1373499), (PMID:8626447)
GO_Central
RGD
PMID:1373499 PMID:1439759 PMID:8626447 GO_REF:0000033 NCBI chr 1:80,493,581...80,497,936 JBrowse link
G Cd79b CD79b molecule involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:8626447)
(PMID:1373499), (PMID:8626447)
GO_Central
RGD
PMID:1373499 PMID:8626447 GO_REF:0000033 NCBI chr10:91,239,354...91,242,500 JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IBA
(PMID:17875758)
GO_REF:0000033
RGD
GO_Central
PMID:17875758 GO_REF:0000033 NCBI chr 9:69,812,859...69,819,959 JBrowse link
G Fcrl5 Fc receptor-like 5 acts_upstream_of ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912 JBrowse link
G Grb2 growth factor receptor bound protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:9199344)
Ensembl
RGD
PMID:9199344 GO_REF:0000107 NCBI chr10:101,380,354...101,448,138 JBrowse link
G Ighe immunoglobulin heavy constant epsilon involved_in ISO (PMID:8976175) RGD PMID:8976175
G Itk IL2-inducible T-cell kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:30,753,344...30,814,685 JBrowse link
G Klhl6 kelch-like family member 6 involved_in ISO (PMID:16166635) RGD PMID:16166635 NCBI chr11:94,475,262...94,514,653 JBrowse link
G Lat2 linker for activation of T cells family, member 2 involved_in ISO
IBA
(PMID:12514734)
GO_REF:0000033
RGD
GO_Central
PMID:12514734 GO_REF:0000033 NCBI chr12:27,740,647...27,754,760 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:7499277)
GO_Central
RGD
PMID:7499277 GO_REF:0000033 NCBI chr 5:147,172,642...147,201,267 JBrowse link
G Lime1 Lck interacting transmembrane adaptor 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:16249387)
GO_Central
RGD
PMID:16249387 GO_REF:0000033 NCBI chr 3:168,490,535...168,496,627 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:3053558 (PMID:23509253), (PMID:7499277) RGD PMID:7499277 PMID:23509253 NCBI chr 5:21,437,127...21,553,097 JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:9254656)
Ensembl
RGD
PMID:9254656 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193 JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(PMID:18955699)
UniProt
RGD
PMID:18955699 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639 JBrowse link
G Mnda myeloid cell nuclear differentiation antigen involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr13:88,550,224...88,567,892 JBrowse link
G Ms4a1 membrane spanning 4-domains A1 involved_in ISO (PMID:18474602) RGD PMID:18474602 NCBI chr 1:217,331,274...217,351,934 JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:17875758)
UniProt
RGD
PMID:17875758 GO_REF:0000024 NCBI chr 7:134,577,470...134,622,928 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15143214)
GO_Central
RGD
PMID:15143214 GO_REF:0000033 NCBI chr 7:116,019,383...116,055,628 JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr 3:157,195,970...157,328,640 JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17367755)
Ensembl
RGD
PMID:17367755 GO_REF:0000107 NCBI chr 2:226,689,745...226,805,897 JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:17367755) RGD PMID:17367755 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:17367755) RGD PMID:17367755 NCBI chr11:58,251,720...58,279,767 JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10925250)
(PMID:11606584), (PMID:15509800)
Ensembl
RGD
PMID:10925250 PMID:11606584 PMID:15509800 GO_REF:0000107 NCBI chr19:62,456,196...62,592,684 JBrowse link
G Plekha1 pleckstrin homology domain containing A1 involved_in ISO (PMID:12101241) RGD PMID:12101241 NCBI chr 1:185,427,982...185,479,157 JBrowse link
G Prkcb protein kinase C, beta involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:12118249)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:12118249 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:186,263,397...186,594,743 JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856074|MGI:3053558 (PMID:23509253), (PMID:9254656)
Ensembl
RGD
PMID:9254656 PMID:23509253 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069 JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:8692271)
MGI:2181288 (PMID:7499277), (PMID:9254656)
UniProt
RGD
PMID:7499277 PMID:8692271 PMID:9254656 GO_REF:0000024 NCBI chr13:49,596,193...49,708,283 JBrowse link
G Rftn1 raftlin lipid raft linker 1 involved_in ISO (PMID:12805216) RGD PMID:12805216 NCBI chr 9:18,302,143...18,499,819 JBrowse link
G Sh2b2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within
ISO (PMID:9233773)
(PMID:10872802)
RGD PMID:9233773 PMID:10872802 NCBI chr12:20,427,057...20,456,845 JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in ISO MGI:98355 (PMID:24043312) RGD PMID:24043312 NCBI chr 6:14,533,870...14,613,348 JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
ISS
GO_REF:0000107
(PMID:9199344)
(PMID:7499277), (PMID:8626447)
GO_REF:0000033
(PMID:15509800)
GO_REF:0000024
Ensembl
RGD
GO_Central
UniProt
PMID:7499277 PMID:8626447 PMID:9199344 PMID:15509800 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437 JBrowse link
G Tec tec protein tyrosine kinase involved_in ISO
IBA
(PMID:10518561)
GO_REF:0000033
RGD
GO_Central
PMID:10518561 GO_REF:0000033 NCBI chr14:35,352,551...35,461,585 JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr 2:197,011,901...197,354,321 JBrowse link
cell surface pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd14 CD14 molecule involved_in ISO (PMID:15294986) RGD PMID:15294986 NCBI chr18:28,609,558...28,611,409 JBrowse link
G Clec7a C-type lectin domain containing 7A acts_upstream_of_or_within
involved_in
ISO (PMID:12719478)
(PMID:19358895)
RGD PMID:12719478 PMID:19358895 NCBI chr 4:164,588,737...164,599,953 JBrowse link
G Fcna ficolin A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:8,445,904...8,449,128 JBrowse link
G Fcnb ficolin B involved_in ISO (PMID:21037097) RGD PMID:21037097 NCBI chr 3:11,393,713...11,402,198 JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in ISO
ISS
(PMID:21037097)
GO_REF:0000024
RGD
UniProt
PMID:21037097 GO_REF:0000024 NCBI chr 1:95,199,277...95,202,599 JBrowse link
G Lbp lipopolysaccharide binding protein involved_in ISO
IEA
(PMID:15294986)
GO_REF:0000107
RGD
Ensembl
PMID:15294986 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941 JBrowse link
G Mbl2 mannose binding lectin 2 involved_in ISO (PMID:22966085) RGD PMID:22966085 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA
(PMID:19358895)
GO_REF:0000107
RGD
Ensembl
PMID:19358895 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437 JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2178675 (PMID:12719478) RGD PMID:12719478 NCBI chr 2:171,499,189...171,504,831 JBrowse link
cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999), (PMID:33542149), (PMID:35322803), (PMID:35438208), (PMID:35460603), (PMID:39322678)
(PMID:39322678)
RGD PMID:32911482 PMID:32912999 PMID:33542149 PMID:35322803 PMID:35438208 More... NCBI chr 8:79,292,282...79,306,998 JBrowse link
G Ddx41 DEAD-box helicase 41 involved_in ISO (PMID:35613581) RGD PMID:35613581 NCBI chr17:9,102,926...9,108,415 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:37832545)
(PMID:25636800), (PMID:30842659), (PMID:30842662), (PMID:35388221), (PMID:37832545)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:25636800 PMID:30842659 PMID:30842662 PMID:35388221 PMID:37832545 GO_REF:0000024 GO_REF:0000107 NCBI chr18:27,332,119...27,338,371 JBrowse link
complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1s complement C1s involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:159,116,549...159,128,736 JBrowse link
G C2 complement C2 involved_in ISO
IBA
(PMID:19302245)
GO_REF:0000033
RGD
GO_Central
PMID:19302245 GO_REF:0000033 NCBI chr20:3,951,474...3,970,376 JBrowse link
G C3 complement C3 acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(PMID:18947875), (PMID:25284781)
GO_REF:0000033
(PMID:19302245)
RGD
GO_Central
PMID:18947875 PMID:19302245 PMID:25284781 PMID:20712003 GO_REF:0000033, RGD:5129529 NCBI chr 9:2,174,412...2,201,339 JBrowse link
G C4a complement C4A acts_upstream_of_or_within
involved_in
TAS
ISO
IBA
(PMID:1438267), (PMID:8133084)
GO_REF:0000033
UniProtKB:P0C0L5 (PMID:19302245)
RGD
GO_Central
PMID:1438267 PMID:8133084 PMID:19302245 PMID:11773063 GO_REF:0000033, RGD:1302926 NCBI chr20:4,005,731...4,020,083 JBrowse link
G C4b complement C4B involved_in
acts_upstream_of_or_within
ISO
IBA
UniProtKB:P0C0L4|UniProtKB:P0C0L5 (PMID:19302245)
MGI:1889070 (PMID:12421924)
GO_REF:0000033
RGD
GO_Central
PMID:12421924 PMID:19302245 GO_REF:0000033 NCBI chr20:4,201,979...4,216,292 JBrowse link
G C6 complement C6 involved_in ISO
IBA
(PMID:2808363)
GO_REF:0000033
RGD
GO_Central
PMID:2808363 GO_REF:0000033 NCBI chr 2:55,573,596...55,648,857 JBrowse link
G C8a complement C8 alpha chain acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:12413696)
GO_REF:0000033
RGD
GO_Central
PMID:12413696 GO_REF:0000033 NCBI chr 5:124,812,131...124,866,631 JBrowse link
G C8b complement C8 beta chain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:124,763,974...124,801,522 JBrowse link
G C8g complement C8 gamma chain involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:28,718,648...28,720,232 JBrowse link
G C9 complement C9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:57,300,510...57,348,759 JBrowse link
G Cfb complement factor B involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:6906329 GO_REF:0000033, RGD:2311339 NCBI chr20:3,975,271...3,981,138 JBrowse link
G Cfh complement factor H acts_upstream_of_or_within
involved_in
IEP
ISO
IBA
(PMID:15574507), (PMID:17517971), (PMID:17921253), (PMID:19411110), (PMID:19541934), (PMID:20675597), (PMID:20702729), (PMID:28057640)
GO_REF:0000033
(PMID:24835392)
RGD
GO_Central
PMID:15574507 PMID:17517971 PMID:17921253 PMID:19411110 PMID:19541934 More... GO_REF:0000033, RGD:1599888 NCBI chr13:54,063,079...54,164,523 JBrowse link
G Cfhr1 complement factor H-related 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:53,946,298...53,961,282 JBrowse link
G Cfhr2 complement factor H-related 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:51,175,824...51,247,924 JBrowse link
G Cfhr2l1 complement factor H-related 2-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:51,262,631...51,296,767 JBrowse link
G Cfhr4 complement factor H-related 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:53,973,301...54,042,179 JBrowse link
G Cfi complement factor I involved_in ISO
IEA
(PMID:18202746)
GO_REF:0000107
RGD
Ensembl
PMID:18202746 GO_REF:0000107 NCBI chr 2:218,389,079...218,430,565 JBrowse link
G Colec11 collectin sub-family member 11 involved_in ISO (PMID:23954398) RGD PMID:23954398 NCBI chr 6:45,223,974...45,256,640 JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within ISO (PMID:20675597) RGD PMID:20675597 NCBI chr13:109,138,132...109,189,068 JBrowse link
G ENSRNOG00000066867 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Lcn12 lipocalin 12 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:28,710,557...28,713,537 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in NAS
IEA
GO_REF:0000002 InterPro
RGD
PMID:12847554 GO_REF:0000002, RGD:633273 NCBI chr11:77,334,794...77,405,271 JBrowse link
G Masp2 MBL associated serine protease 2 NAS RGD PMID:10586086 RGD:633276 NCBI chr 5:159,035,892...159,049,561 JBrowse link
G Rgcc regulator of cell cycle involved_in ISO (PMID:19162005) RGD PMID:19162005 NCBI chr15:61,071,574...61,084,408 JBrowse link
complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 9:2,174,412...2,201,339 JBrowse link
G C5 complement C5 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:38,668,174...38,759,468 JBrowse link
G C5l1 complement C5 like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:18,401,716...18,420,064 JBrowse link
G C8a complement C8 alpha chain involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:124,812,131...124,866,631 JBrowse link
G C8b complement C8 beta chain involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:124,763,974...124,801,522 JBrowse link
G C9 complement C9 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:57,300,510...57,348,759 JBrowse link
G Cfb complement factor B acts_upstream_of_or_within ISO MGI:1861129 (PMID:27564415), (PMID:9238044) RGD PMID:9238044 PMID:27564415 NCBI chr20:3,975,271...3,981,138 JBrowse link
G Cfd complement factor D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:27564415)
Ensembl
RGD
PMID:27564415 GO_REF:0000107 NCBI chr 7:10,463,773...10,465,496 JBrowse link
G Cfh complement factor H acts_upstream_of_or_within
acts_upstream_of_or_within_negative_effect
ISO (PMID:27564415)
(PMID:19828624)
RGD PMID:19828624 PMID:27564415 NCBI chr13:54,063,079...54,164,523 JBrowse link
G Cfp complement factor properdin involved_in ISO MGI:3774548 (PMID:18292556) RGD PMID:18292556 NCBI chr  X:3,715,551...3,721,113 JBrowse link
G Cr2 complement C3d receptor 2 involved_in
acts_upstream_of_or_within_negative_effect
ISO (PMID:11981823)
(PMID:19828624)
RGD PMID:11981823 PMID:19828624 NCBI chr13:106,678,579...106,716,595 JBrowse link
complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07006691.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G C1qa complement C1q A chain involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:29449492)
MGI:2158701 (PMID:11901193)
GO_REF:0000107
RGD
Ensembl
PMID:11901193 PMID:29449492 GO_REF:0000107 NCBI chr 5:154,417,086...154,419,933 JBrowse link
G C1qb complement C1q B chain involved_in ISO (PMID:29449492) RGD PMID:29449492 NCBI chr 5:154,402,276...154,407,827 JBrowse link
G C1qbp complement C1q binding protein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr10:56,198,534...56,203,185 JBrowse link
G C1qc complement C1q C chain involved_in ISO
IEA
(PMID:29449492)
GO_REF:0000107
RGD
Ensembl
PMID:29449492 GO_REF:0000107 NCBI chr 5:149,127,412...149,130,757 JBrowse link
G C1r complement C1r involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:159,099,013...159,109,770 JBrowse link
G C1rl complement C1r subcomponent like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:157,394,183...157,410,771 JBrowse link
G C1s complement C1s involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 4:159,116,549...159,128,736 JBrowse link
G C2 complement C2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:3,951,474...3,970,376 JBrowse link
G C3 complement C3 involved_in TAS
IEA
GO_REF:0000043 UniProt
RGD
PMID:16996480 GO_REF:0000043, RGD:1600605 NCBI chr 9:2,174,412...2,201,339 JBrowse link
G C4a complement C4A involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:4,005,731...4,020,083 JBrowse link
G C4b complement C4B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:4,201,979...4,216,292 JBrowse link
G C4bpa complement component 4 binding protein, alpha involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:44,627,959...44,663,552 JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:44,673,064...44,683,781 JBrowse link
G C5 complement C5 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:38,668,174...38,759,468 JBrowse link
G C5l1 complement C5 like 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:18,401,716...18,420,064 JBrowse link
G C6 complement C6 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:55,573,596...55,648,857 JBrowse link
G C8a complement C8 alpha chain involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:124,812,131...124,866,631 JBrowse link
G C8b complement C8 beta chain involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:124,763,974...124,801,522 JBrowse link
G C9 complement C9 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:57,300,510...57,348,759 JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:44,409,574...44,438,913 JBrowse link
G Cfb complement factor B involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr20:3,975,271...3,981,138 JBrowse link
G Cfi complement factor I involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 2:218,389,079...218,430,565 JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr13:109,138,132...109,189,068 JBrowse link
G Crp C-reactive protein IMP RGD PMID:16367929 RGD:1580273 NCBI chr13:87,694,062...87,695,978 JBrowse link
G ENSRNOG00000065917 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G ENSRNOG00000070986 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G IgG-2a gamma-2a immunoglobulin heavy chain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Igh-6 immunoglobulin heavy chain 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Ighg1 immunoglobulin heavy constant gamma 1 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:6952213)
GO_Central
RGD
PMID:6952213 GO_REF:0000033
G Masp2 MBL associated serine protease 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 5:159,035,892...159,049,561 JBrowse link
G Mbl1 mannose binding lectin 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:17,063,232...17,069,271 JBrowse link
G Mbl2 mannose binding lectin 2 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:90,249,410...90,259,299 JBrowse link
complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07006691.1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043
G Cd69 Cd69 molecule TAS RGD PMID:11034393 PMID:15506986 RGD:1354527, RGD:1354528 NCBI chr 4:164,411,485...164,419,403 JBrowse link
G Colec10 collectin subfamily member 10 involved_in ISO (PMID:24174618) RGD PMID:24174618 NCBI chr 7:85,744,895...85,806,368 JBrowse link
G Colec11 collectin sub-family member 11 involved_in ISO (PMID:24174618), (PMID:25912189) RGD PMID:24174618 PMID:25912189 NCBI chr 6:45,223,974...45,256,640 JBrowse link
G Fcna ficolin A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:8,445,904...8,449,128 JBrowse link
G Fcnb ficolin B involved_in ISO
IBA
(PMID:16116205)
GO_REF:0000033
RGD
GO_Central
PMID:16116205 GO_REF:0000033 NCBI chr 3:11,393,713...11,402,198 JBrowse link
G Krt1 keratin 1 involved_in ISO
IEA
UniProtKB:P11226 (PMID:11549596)
GO_REF:0000107
RGD
Ensembl
PMID:11549596 GO_REF:0000107 NCBI chr 7:134,855,311...134,860,537 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISS
ISO
IBA
IEA
GO_REF:0000024
(PMID:18424734)
GO_REF:0000033
GO_REF:0000107
(PMID:17182967)
UniProt
RGD
GO_Central
Ensembl
PMID:17182967 PMID:18424734 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr11:77,334,794...77,405,271 JBrowse link
G Masp2 MBL associated serine protease 2 involved_in ISO
IBA
IEA
(PMID:17182967), (PMID:9087411)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:9087411 PMID:17182967 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:159,035,892...159,049,561 JBrowse link
G Mbl1 mannose binding lectin 1 acts_upstream_of_or_within IDA
ISO
MGI:96924 (PMID:15148336) RGD PMID:15148336 PMID:16272342 RGD:1582134 NCBI chr16:17,063,232...17,069,271 JBrowse link
G Mbl2 mannose binding lectin 2 acts_upstream_of_or_within
involved_in
ISO (PMID:15148336)
MGI:3577339|MGI:96923 (PMID:15148336)
UniProtKB:P04264 (PMID:11549596), (PMID:22691502), (PMID:35102342)
RGD PMID:11549596 PMID:15148336 PMID:22691502 PMID:35102342 NCBI chr 1:237,429,873...237,465,567 JBrowse link
complement component C5a signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3ar1 complement C3a receptor 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 4:157,747,419...157,756,609 JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO (PMID:10571060) RGD PMID:10571060 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432 JBrowse link
complement receptor mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO
GO_REF:0000107
(PMID:22632727)
Ensembl
RGD
PMID:22632727 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339 JBrowse link
G C3ar1 complement C3a receptor 1 involved_in IEA
IBA
ISO
GO_REF:0000107
GO_REF:0000033
(PMID:10571060)
Ensembl
GO_Central
RGD
PMID:10571060 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:157,747,419...157,756,609 JBrowse link
G C5ar1 complement C5a receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:86,077,309...86,088,001 JBrowse link
G C5ar2 complement C5a receptor 2 involved_in IEA
IBA
GO_REF:0000108
GO_REF:0000033
GOC
GO_Central
GO_REF:0000033 GO_REF:0000108 NCBI chr 1:76,930,381...76,945,432 JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:42,974,462...43,027,321 JBrowse link
G Cr2 complement C3d receptor 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr13:106,678,579...106,716,595 JBrowse link
G Fpr1 formyl peptide receptor 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:67,417,991...67,429,813 JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:67,449,637...67,458,272 JBrowse link
G Fpr2l1 formyl peptide receptor 2 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:59,686,519...59,687,550 JBrowse link
G Fpr2l2 formyl peptide receptor 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:58,997,091...58,998,062 JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15907827), (PMID:19135435)
UniProt
Ensembl
RGD
PMID:15907827 PMID:19135435 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,512,659...40,560,483 JBrowse link
G Gpr33-ps1 G protein-coupled receptor 33, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:69,474,435...69,475,440 JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) RGD PMID:22632727 NCBI chr 1:192,089,496...192,139,947 JBrowse link
cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alpk1 alpha-kinase 1 involved_in ISO
IBA
(PMID:28222186), (PMID:28877472), (PMID:30111836)
(PMID:30111836)
GO_REF:0000033
RGD
GO_Central
PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000033 NCBI chr 2:218,801,425...218,924,013 JBrowse link
G Becn1 beclin 1 involved_in ISO (PMID:34796041) RGD PMID:34796041 NCBI chr10:86,731,649...86,747,002 JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) RGD PMID:23258413 NCBI chr 8:79,292,282...79,306,998 JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:23478265) RGD PMID:23478265 NCBI chr  X:9,479,532...9,493,169 JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IBA
(PMID:19211564)
GO_REF:0000033
RGD
GO_Central
PMID:19211564 GO_REF:0000033 NCBI chr10:86,120,677...86,132,095 JBrowse link
G Ipo5 importin 5 involved_in ISO (PMID:31340999) RGD PMID:31340999 NCBI chr15:104,397,626...104,447,985 JBrowse link
G Irf3 interferon regulatory factor 3 involved_in ISO (PMID:8524823) RGD PMID:8524823 NCBI chr 1:104,616,608...104,621,402 JBrowse link
G Irf7 interferon regulatory factor 7 involved_in ISO (PMID:21931555) RGD PMID:21931555 NCBI chr 1:205,796,956...205,800,543 JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISO (PMID:16125763), (PMID:20451243) RGD PMID:16125763 PMID:20451243 NCBI chr 3:118,451,650...118,466,094 JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO
IBA
(PMID:19576794)
GO_REF:0000033
RGD
GO_Central
PMID:19576794 GO_REF:0000033 NCBI chr 5:60,117,398...60,165,995 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378), (PMID:35388221) RGD PMID:23910378 PMID:35388221 NCBI chr18:27,332,119...27,338,371 JBrowse link
G Tbk1 TANK-binding kinase 1 involved_in ISO (PMID:29441066) RGD PMID:29441066 NCBI chr 7:58,963,319...58,996,357 JBrowse link
G Tifa TRAF-interacting protein with forkhead-associated domain involved_in ISO
IBA
ISS
(PMID:26068852), (PMID:28222186), (PMID:28877472), (PMID:30111836)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:26068852 PMID:28222186 PMID:28877472 PMID:30111836 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:216,257,926...216,267,635 JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 involved_in ISO
IBA
(PMID:31390091)
GO_REF:0000033
RGD
GO_Central
PMID:31390091 GO_REF:0000033 NCBI chr13:104,694,802...104,719,655 JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in IEA
ISO
GO_REF:0000107
(PMID:20501938), (PMID:23015697)
Ensembl
RGD
PMID:20501938 PMID:23015697 GO_REF:0000107 NCBI chr 3:108,418,537...108,443,330 JBrowse link
G Trim25 tripartite motif-containing 25 involved_in ISO (PMID:17392790) RGD PMID:17392790 NCBI chr10:73,812,818...73,831,271 JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:22607805) RGD PMID:22607805 NCBI chr10:61,082,934...61,120,618 JBrowse link
endolysosomal toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Washc4 WASH complex subunit 4 acts_upstream_of_or_within ISO (PMID:33749590) RGD PMID:33749590 NCBI chr 7:20,187,905...20,240,228 JBrowse link
Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:14764707)
GO_Central
RGD
PMID:14764707 GO_REF:0000033 NCBI chr13:83,649,447...83,654,248 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:16272347)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:16272347 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:21,437,127...21,553,097 JBrowse link
Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc epsilon receptor II involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr12:1,742,809...1,754,476 JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:7544003) RGD PMID:7544003 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Myo1g myosin IG involved_in ISO (PMID:23038771) RGD PMID:23038771 NCBI chr14:85,600,619...85,615,760 JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO
IEA
(PMID:7544003)
GO_REF:0000107
RGD
Ensembl
PMID:7544003 GO_REF:0000107 NCBI chr10:64,313,335...64,349,221 JBrowse link
helper T cell enhancement of adaptive immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd4 Cd4 molecule involved_in ISO (PMID:1832488) RGD PMID:1832488 NCBI chr 4:157,668,878...157,695,366 JBrowse link
immune response-activating cell surface receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO
IEA
(PMID:18852879)
GO_REF:0000107
RGD
Ensembl
PMID:18852879 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414 JBrowse link
G Micb MHC class I polypeptide-related sequence B involved_in ISO (PMID:11491531) RGD PMID:11491531 NCBI chr 1:78,495,779...78,513,030 JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in ISS
IBA
IEA
ISO
GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
(PMID:18852879)
UniProt
GO_Central
Ensembl
InterPro
RGD
PMID:18852879 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,637,242...3,643,748 JBrowse link
immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300lb CD300 molecule-like family member b involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,463,815...100,473,804 JBrowse link
G Cd300ld Cd300 molecule-like family member D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,082,957...100,115,853 JBrowse link
G Cd300ldl1 Cd300 molecule-like family member D like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,056,712...100,078,276 JBrowse link
G Cd300le Cd300 molecule-like family member E involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,271,076...100,280,400 JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:100,858,924...100,875,111 JBrowse link
G Tmigd3 transmembrane and immunoglobulin domain containing 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:193,338,950...193,415,107 JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
ISO
GO_REF:0000024
(PMID:19909337)
UniProt
RGD
PMID:19909337 GO_REF:0000024 NCBI chr 5:137,376,562...137,385,351 JBrowse link
inflammasome-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elp6 elongator acetyltransferase complex subunit 6 acts_upstream_of_or_within ISO (PMID:30097576) RGD PMID:30097576 NCBI chr 8:110,280,059...110,295,070 JBrowse link
innate immune response-activating signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tlr4 toll-like receptor 4 IMP RGD PMID:19226379 RGD:2312509 NCBI chr 5:85,161,247...85,174,882 JBrowse link
MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO
IBA
(PMID:17600090), (PMID:19211564), (PMID:33727702)
GO_REF:0000033
RGD
GO_Central
PMID:17600090 PMID:19211564 PMID:33727702 GO_REF:0000033 NCBI chr 3:67,635,924...67,683,968 JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 involved_in ISO
IEA
(PMID:30078389)
GO_REF:0000107
RGD
Ensembl
PMID:30078389 GO_REF:0000107 NCBI chr12:41,439,645...41,463,392 JBrowse link
MyD88-dependent toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) RGD PMID:19265123 NCBI chr 8:119,969,908...120,071,270 JBrowse link
MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:14660645) RGD PMID:14660645 NCBI chr12:11,009,236...11,015,941 JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:16148103) RGD PMID:16148103 NCBI chr 9:64,073,610...64,084,332 JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000002
MGI:1346060|MGI:2385681 (PMID:12719478), (PMID:12872135), (PMID:14764662)
InterPro
RGD
PMID:12719478 PMID:12872135 PMID:14764662 GO_REF:0000002 NCBI chr 8:127,952,161...127,956,230 JBrowse link
G Reg3g regenerating family member 3 gamma involved_in ISS
ISO
GO_REF:0000024
(PMID:17635956)
UniProt
RGD
PMID:17635956 GO_REF:0000024 NCBI chr 4:112,482,183...112,484,738 JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:108005 (PMID:12719478) RGD PMID:12719478 NCBI chr 2:171,499,189...171,504,831 JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
IBA
GO_REF:0000107
(PMID:20037584), (PMID:38670073)
UniProtKB:Q9EPW9 (PMID:20037584)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:20037584 PMID:38670073 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO (PMID:20037584)
UniProtKB:Q9QUK6 (PMID:20037584)
RGD PMID:20037584 NCBI chr14:43,715,809...43,727,019 JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO UniProtKB:P22366 (PMID:18820679) RGD PMID:18820679 NCBI chr 8:106,864,680...106,868,796 JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 involved_in ISO (PMID:22011580) RGD PMID:22011580 NCBI chr10:39,537,759...39,585,038 JBrowse link
MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrfip2 LRR binding FLII interacting protein 2 acts_upstream_of_or_within ISO (PMID:19265123) RGD PMID:19265123 NCBI chr 8:119,969,908...120,071,270 JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 9:1,189,717...1,197,730 JBrowse link
G Tnip3 TNFAIP3 interacting protein 3 involved_in ISO (PMID:17088249) RGD PMID:17088249 NCBI chr 4:96,197,019...96,237,357 JBrowse link
negative regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd59b CD59b molecule acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
(PMID:10946279), (PMID:11471050)
GO_REF:0000033
RGD
GO_Central
PMID:10946279 PMID:11471050 PMID:15843577 GO_REF:0000033, RGD:1600482 NCBI chr 3:110,914,008...110,932,489 JBrowse link
G LOC134480016 urinary protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Rup2l2 urinary protein 2 like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:35,750,482...35,754,083 JBrowse link
negative regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim11 tripartite motif-containing 11 involved_in ISS
ISO
GO_REF:0000024
(PMID:27498865)
UniProt
RGD
PMID:27498865 GO_REF:0000024 NCBI chr10:43,758,299...43,771,138 JBrowse link
negative regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd22 CD22 molecule involved_in ISO
IBA
(PMID:24169826), (PMID:26017478)
GO_REF:0000033
RGD
GO_Central
PMID:24169826 PMID:26017478 GO_REF:0000033 NCBI chr 1:95,243,785...95,270,430 JBrowse link
G Cd300a Cd300a molecule involved_in ISO (PMID:21482706) RGD PMID:21482706 NCBI chr10:100,428,826...100,441,693 JBrowse link
G Cd72 Cd72 molecule involved_in ISO (PMID:1711157) RGD PMID:1711157 NCBI chr 5:57,697,361...57,704,980 JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr13:85,725,897...85,740,517 JBrowse link
G Fcrl5 Fc receptor-like 5 acts_upstream_of_or_within ISO MGI:96055|MGI:96892 (PMID:23509253) RGD PMID:23509253 NCBI chr 2:172,881,763...172,912,912 JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:54,637,360...54,640,542 JBrowse link
G Lpxn leupaxin involved_in ISO
IBA
(PMID:17640867)
GO_REF:0000033
RGD
GO_Central
PMID:17640867 GO_REF:0000033 NCBI chr 1:209,928,297...209,963,085 JBrowse link
G Mir34a microRNA 34a involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 5:165,815,952...165,816,053 JBrowse link
G Plcl2 phospholipase C-like 2 acts_upstream_of_or_within ISO MGI:2679632 (PMID:14517301) RGD PMID:14517301 NCBI chr 9:3,292,564...3,477,009 JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in ISO
IEA
(PMID:35941532)
GO_REF:0000107
RGD
Ensembl
PMID:35941532 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069 JBrowse link
negative regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial involved_in ISO
IEA
ISS
(PMID:39322678)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:39322678 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,484,639...15,496,116 JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:12172553), (PMID:26440888)
Ensembl
RGD
PMID:12172553 PMID:26440888 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131 JBrowse link
G Aurkb aurora kinase B involved_in IEA
ISO
GO_REF:0000107
(PMID:33542149)
Ensembl
RGD
PMID:33542149 GO_REF:0000107 NCBI chr10:54,243,116...54,249,675 JBrowse link
G Banf1 barrier to autointegration nuclear assembly factor 1 involved_in ISO (PMID:32792394) RGD PMID:32792394 NCBI chr 1:202,672,170...202,674,215 JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:32911482), (PMID:32912999) RGD PMID:32911482 PMID:32912999 NCBI chr 8:79,292,282...79,306,998 JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:32715615) RGD PMID:32715615 NCBI chr10:33,734,640...33,742,720 JBrowse link
G Lyplal1 lysophospholipase-like 1 involved_in ISO (PMID:37802025) RGD PMID:37802025 NCBI chr13:97,626,568...97,657,901 JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:35460603) RGD PMID:35460603 NCBI chr13:94,839,484...94,871,295 JBrowse link
G Pcbp2 poly(rC) binding protein 2 involved_in ISO (PMID:35322803) RGD PMID:35322803 NCBI chr 7:133,605,375...133,631,312 JBrowse link
G Ppp6c protein phosphatase 6, catalytic subunit involved_in ISO (PMID:32474700) RGD PMID:32474700 NCBI chr 3:22,929,816...22,962,123 JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:33273464) RGD PMID:33273464 NCBI chr11:98,544,952...98,762,499 JBrowse link
G Smpdl3a sphingomyelin phosphodiesterase, acid-like 3A involved_in ISS
ISO
GO_REF:0000024
(PMID:37890481)
UniProt
RGD
PMID:37890481 GO_REF:0000024 NCBI chr20:37,132,592...37,155,567 JBrowse link
G Spsb3 splA/ryanodine receptor domain and SOCS box containing 3 involved_in ISO (PMID:38418882) RGD PMID:38418882 NCBI chr10:13,907,175...13,912,841 JBrowse link
G Trex1 three prime repair exonuclease 1 involved_in ISO (PMID:33476576) RGD PMID:33476576 NCBI chr 8:109,706,613...109,707,913 JBrowse link
G Zdhhc18 zinc finger DHHC-type palmitoyltransferase 18 involved_in IEA
ISO
GO_REF:0000107
(PMID:35438208)
Ensembl
RGD
PMID:35438208 GO_REF:0000107 NCBI chr 5:151,105,303...151,143,843 JBrowse link
negative regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in IDA
ISO
(PMID:28657829), (PMID:6211481) RGD PMID:6211481 PMID:28657829 PMID:10929073 RGD:2326180 NCBI chr13:44,409,574...44,438,913 JBrowse link
G Cd59b CD59b molecule acts_upstream_of_or_within ISO (PMID:10946279) RGD PMID:10946279 NCBI chr 3:110,914,008...110,932,489 JBrowse link
G Cr1l complement C3b/C4b receptor 1 like acts_upstream_of_or_within IMP
ISO
MGI:2158683 (PMID:10642554) RGD PMID:10642554 PMID:11861390 RGD:625470 NCBI chr13:109,138,132...109,189,068 JBrowse link
G Masp1 MBL associated serine protease 1 involved_in ISO (PMID:11485744) RGD PMID:11485744 NCBI chr11:77,334,794...77,405,271 JBrowse link
negative regulation of complement activation, alternative pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:9029106) RGD PMID:9029106 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) RGD PMID:23482636 NCBI chr13:96,982,867...97,109,419 JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in ISO
IBA
UniProtKB:P01024 (PMID:17051150)
GO_REF:0000033
RGD
GO_Central
PMID:17051150 GO_REF:0000033 NCBI chr  X:61,144,926...61,170,212 JBrowse link
negative regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C4bpa complement component 4 binding protein, alpha involved_in ISO
IBA
IEA
(PMID:22333221)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:22333221 GO_REF:0000033 GO_REF:0000107 NCBI chr13:44,627,959...44,663,552 JBrowse link
G C4bpb complement component 4 binding protein, beta involved_in ISO
IEA
(PMID:22333221)
GO_REF:0000107
RGD
Ensembl
PMID:22333221 GO_REF:0000107 NCBI chr13:44,673,064...44,683,781 JBrowse link
G Cd46 CD46 molecule involved_in ISO
IBA
(PMID:9029106)
GO_REF:0000033
RGD
GO_Central
PMID:9029106 GO_REF:0000033 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Cd46l1 CD46 molecule like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:33,996,404...33,997,405 JBrowse link
G Cr1l complement C3b/C4b receptor 1 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:109,138,132...109,189,068 JBrowse link
G Cr2 complement C3d receptor 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:106,678,579...106,716,595 JBrowse link
G Susd4 sushi domain containing 4 involved_in ISO (PMID:23482636) RGD PMID:23482636 NCBI chr13:96,982,867...97,109,419 JBrowse link
G Zp3r zona pellucida 3 receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:42,019,998...42,064,836 JBrowse link
negative regulation of complement activation, lectin pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin involved_in ISO (PMID:12538697) RGD PMID:12538697 NCBI chr 4:156,570,163...156,619,870 JBrowse link
G Serping1 serpin family G member 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:10946292)
UniProt
RGD
PMID:10946292 GO_REF:0000024 NCBI chr 3:90,249,410...90,259,299 JBrowse link
negative regulation of cytoplasmic pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:27736772) RGD PMID:27736772 NCBI chr 3:143,642,348...143,733,745 JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:33674311) RGD PMID:33674311 NCBI chr20:1,604,794...1,610,283 JBrowse link
G Tarbp2 Tarbp2 subunit of RISC loading complex involved_in ISO (PMID:30927622) RGD PMID:30927622 NCBI chr 7:133,649,118...133,654,306 JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:27736772) RGD PMID:27736772 NCBI chr 4:81,821,991...81,877,906 JBrowse link
G Tspan6 tetraspanin 6 involved_in ISO (PMID:22908223) RGD PMID:22908223 NCBI chr  X:101,385,686...101,395,371 JBrowse link
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in ISO (PMID:25568335) RGD PMID:25568335 NCBI chr16:2,118,503...2,166,741 JBrowse link
negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS
(PMID:19164550)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,198,534...56,203,185 JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21187438) RGD PMID:21187438 NCBI chr10:86,120,677...86,132,095 JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) RGD PMID:25865883 NCBI chr18:3,602,535...3,628,108 JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:17600090)
UniProt
Ensembl
RGD
PMID:17600090 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,238,230...207,253,035 JBrowse link
negative regulation of MyD88-dependent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:22043923) RGD PMID:22043923 NCBI chr10:100,428,826...100,441,693 JBrowse link
G Cd300lf Cd300 molecule-like family member F involved_in ISS
ISO
GO_REF:0000024
(PMID:22043923)
UniProt
RGD
PMID:22043923 GO_REF:0000024 NCBI chr10:100,858,924...100,875,111 JBrowse link
negative regulation of MyD88-independent toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,369,456...63,393,016 JBrowse link
negative regulation of NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17a abhydrolase domain containing 17A, depalmitoylase involved_in ISO (PMID:38092000) RGD PMID:38092000 NCBI chr 7:9,124,332...9,132,762 JBrowse link
G Cptp ceramide-1-phosphate transfer protein involved_in ISO
ISS
(PMID:29164996)
GO_REF:0000024
RGD
UniProt
PMID:29164996 GO_REF:0000024 NCBI chr 5:166,474,947...166,479,103 JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:34615873)
UniProt
RGD
PMID:34615873 GO_REF:0000024 NCBI chr18:55,017,049...55,050,184 JBrowse link
G Fbxl2 F-box and leucine-rich repeat protein 2 involved_in ISO (PMID:26037928) RGD PMID:26037928 NCBI chr 8:113,916,660...113,965,137 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr 8:50,080,514...50,084,376 JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
ISO
GO_REF:0000024
(PMID:30612879)
UniProt
RGD
PMID:30612879 GO_REF:0000024 NCBI chr10:33,734,640...33,742,720 JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in ISO (PMID:36586411) RGD PMID:36586411 NCBI chr  X:122,038,734...122,087,745 JBrowse link
G Mefv MEFV innate immunity regulator, pyrin involved_in ISS
ISO
GO_REF:0000024
(PMID:26347139)
UniProt
RGD
PMID:26347139 GO_REF:0000024 NCBI chr10:11,786,948...11,796,977 JBrowse link
G Nlrc3 NLR family, CARD domain containing 3 involved_in ISO (PMID:25277106) RGD PMID:25277106 NCBI chr10:11,551,378...11,585,027 JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 NCBI chr 1:93,181,472...93,204,499 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 acts_upstream_of_or_within ISO (PMID:32514138)
(PMID:29887864)
RGD PMID:29887864 PMID:32514138 NCBI chr 9:12,647,605...12,654,190 JBrowse link
G Trim31 tripartite motif-containing 31 involved_in ISO (PMID:27929086) RGD PMID:27929086 NCBI chr20:1,658,386...1,671,711 JBrowse link
G Zdhhc12 zinc finger DHHC-type palmitoyltransferase 12 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:36586411)
UniProt
Ensembl
RGD
PMID:36586411 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:13,363,504...13,366,383 JBrowse link
negative regulation of non-canonical inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:37962578)
UniProt
Ensembl
RGD
PMID:37962578 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148 JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) RGD PMID:18342009 NCBI chr 1:15,528,921...15,543,993 JBrowse link
negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Erbin erbb2 interacting protein involved_in ISO (PMID:16203728) RGD PMID:16203728 NCBI chr 2:34,926,962...35,028,440 JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:194,055,165...194,103,209 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:18342009) RGD PMID:18342009 NCBI chr 1:15,528,921...15,543,993 JBrowse link
G Znrf4 zinc and ring finger 4 involved_in ISO (PMID:28656966) RGD PMID:28656966 NCBI chr 9:1,353,308...1,354,496 JBrowse link
negative regulation of RIG-I signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
IEA
ISS
(PMID:19164550)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:56,198,534...56,203,185 JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO
IBA
(PMID:18411269), (PMID:21187438)
(PMID:17475874)
GO_REF:0000033
RGD
GO_Central
PMID:17475874 PMID:18411269 PMID:21187438 GO_REF:0000033 NCBI chr10:86,120,677...86,132,095 JBrowse link
G Gpatch3 G patch domain containing 3 involved_in ISO
IBA
(PMID:28414768)
GO_REF:0000033
RGD
GO_Central
PMID:28414768 GO_REF:0000033 NCBI chr 5:145,800,107...145,809,519 JBrowse link
G Nlrx1 NLR family member X1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5141085 (PMID:21703540)
Ensembl
RGD
PMID:21703540 GO_REF:0000107 NCBI chr 8:44,588,476...44,606,678 JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor involved_in ISO
IEA
ISS
(PMID:26471729)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr10:106,152,756...106,208,306 JBrowse link
G Rnf125 ring finger protein 125 involved_in ISO (PMID:17460044), (PMID:26471729) RGD PMID:17460044 PMID:26471729 NCBI chr18:12,528,995...12,550,646 JBrowse link
G Sec14l1 SEC14-like lipid binding 1 involved_in ISO
IBA
(PMID:23843640)
GO_REF:0000033
RGD
GO_Central
PMID:23843640 GO_REF:0000033 NCBI chr10:102,319,920...102,367,070 JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 involved_in ISO
IEA
ISS
(PMID:26471729)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:26471729 GO_REF:0000024 GO_REF:0000107 NCBI chr11:95,665,971...95,689,423 JBrowse link
negative regulation of T cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within ISO (PMID:23589618) RGD PMID:23589618 NCBI chr17:41,620,807...41,632,621 JBrowse link
G Btnl2 butyrophilin-like 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16751379)
Ensembl
RGD
PMID:16751379 GO_REF:0000107 NCBI chr20:4,490,169...4,504,002 JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase involved_in ISO (PMID:38225265) RGD PMID:38225265 NCBI chr 1:244,210,299...244,380,126 JBrowse link
G Cblb Cbl proto-oncogene B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180572 (PMID:14738763)
Ensembl
RGD
PMID:14738763 GO_REF:0000107 NCBI chr11:62,058,829...62,225,904 JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:18193050) RGD PMID:18193050 NCBI chr 2:184,340,820...184,383,421 JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:90,171,401...90,187,810 JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in ISS
ISO
GO_REF:0000024
(PMID:12883552)
UniProt
RGD
PMID:12883552 GO_REF:0000024 NCBI chr 3:77,904,149...77,946,114 JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within
involved_in
ISO (PMID:24714587)
(PMID:38225265)
RGD PMID:24714587 PMID:38225265 NCBI chr17:33,780,980...33,831,241 JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO
IBA
(PMID:12447358)
GO_REF:0000033
RGD
GO_Central
PMID:12447358 GO_REF:0000033 NCBI chr10:86,920,014...86,933,739 JBrowse link
G Elf1 E74 like ETS transcription factor 1 acts_upstream_of_or_within ISO MGI:1926074 (PMID:14738763) RGD PMID:14738763 NCBI chr15:54,890,644...54,986,721 JBrowse link
G Ezr ezrin involved_in ISO
IEA
(PMID:20551903)
GO_REF:0000107
RGD
Ensembl
PMID:20551903 GO_REF:0000107 NCBI chr 1:49,373,033...49,416,573 JBrowse link
G Gbp1 guanylate binding protein 1 involved_in ISO (PMID:24337748) RGD PMID:24337748 NCBI chr 2:234,071,366...234,106,012 JBrowse link
G Itpripl1 ITPRIP like 1 involved_in ISO
IEA
(PMID:38614099)
GO_REF:0000107
RGD
Ensembl
PMID:38614099 GO_REF:0000107 NCBI chr 3:114,403,123...114,407,917 JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:143,087,759...143,109,807 JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:19706535) RGD PMID:19706535 NCBI chr15:23,099,795...23,111,731 JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035), (PMID:22387553) RGD PMID:16493035 PMID:22387553 NCBI chr 1:78,847,685...78,853,294 JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:38614099) RGD PMID:38614099 NCBI chr 8:109,897,723...109,958,247 JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (PMID:12970181) RGD PMID:12970181 NCBI chr 7:45,531,480...45,611,492 JBrowse link
G Phpt1 phosphohistidine phosphatase 1 involved_in ISO (PMID:18796614) RGD PMID:18796614 NCBI chr 3:28,791,062...28,792,905 JBrowse link
G Prnp prion protein involved_in ISO (PMID:20145049) RGD PMID:20145049 NCBI chr 3:139,639,076...139,654,420 JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:22080863)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22080863 GO_REF:0000024 GO_REF:0000107 NCBI chr18:61,229,012...61,294,662 JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:18056643) RGD PMID:18056643 NCBI chr 2:194,055,165...194,103,209 JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1856074 (PMID:9064344)
Ensembl
RGD
PMID:9064344 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069 JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (PMID:11259588), (PMID:12913111), (PMID:9780142)
(PMID:12913111)
RGD PMID:9780142 PMID:11259588 PMID:12913111 NCBI chr 3:76,405,917...76,561,842 JBrowse link
G Pvrig PVR related immunoglobulin domain containing involved_in ISO
IBA
(PMID:26755705)
GO_REF:0000033
RGD
GO_Central
PMID:26755705 GO_REF:0000033 NCBI chr12:17,363,721...17,365,577 JBrowse link
G Sh2d1a SH2 domain containing 1A involved_in ISO (PMID:9774102) RGD PMID:9774102 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sla2 Src-like-adaptor 2 involved_in ISO (PMID:11891219) RGD PMID:11891219 NCBI chr 3:145,367,070...145,383,586 JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in ISS
ISO
GO_REF:0000024
(PMID:9285719)
UniProt
RGD
PMID:9285719 GO_REF:0000024 NCBI chr 8:53,286,396...53,291,541 JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:107180 (PMID:14738763)
GO_Central
RGD
PMID:14738763 GO_REF:0000033 NCBI chr20:9,291,471...9,334,685 JBrowse link
negative regulation of toll-like receptor 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:79,871,819...79,881,101 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(PMID:20385881)
UniProt
RGD
PMID:20385881 GO_REF:0000024 NCBI chr 5:21,437,127...21,553,097 JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:26599367) RGD PMID:26599367 NCBI chr16:56,545,462...56,633,649 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:2680581 (PMID:15220916) RGD PMID:15220916 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:O60603 (PMID:22198949) RGD PMID:22198949 NCBI chr14:43,715,809...43,727,019 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31134514) RGD PMID:31134514 NCBI chr 9:12,647,605...12,654,190 JBrowse link
negative regulation of toll-like receptor 3 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:19865078) RGD PMID:19865078 NCBI chr 2:26,772,274...26,785,226 JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:15474016) RGD PMID:15474016 NCBI chr 1:15,528,921...15,543,993 JBrowse link
G Ubqln1 ubiquilin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:21695056)
Ensembl
RGD
PMID:21695056 GO_REF:0000107 NCBI chr17:6,439,002...6,477,096 JBrowse link
negative regulation of toll-like receptor 4 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23609450) RGD PMID:23609450 NCBI chr15:79,871,819...79,881,101 JBrowse link
G Bpifb1 BPI fold containing family B, member 1 involved_in ISO
IBA
IEA
(PMID:21900486)
GO_REF:0000033
GO_REF:0000107
RGD
GO_Central
Ensembl
PMID:21900486 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:142,672,995...142,706,258 JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19948740)
UniProt
Ensembl
RGD
PMID:19948740 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:18,915,290...19,086,282 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(PMID:20385881)
UniProt
RGD
PMID:20385881 GO_REF:0000024 NCBI chr 5:21,437,127...21,553,097 JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:28609714) RGD PMID:28609714 NCBI chr16:56,545,462...56,633,649 JBrowse link
G Mir140 microRNA 140 involved_in ISO UniProtKB:O00206 (PMID:30233718), (PMID:30321456) RGD PMID:30233718 PMID:30321456 NCBI chr19:52,375,293...52,375,391 JBrowse link
G Mir200b microRNA 200b involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 5:166,649,272...166,649,366 JBrowse link
G Mir200c microRNA 200c involved_in ISO (PMID:22522429) RGD PMID:22522429 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:29653364) RGD PMID:29653364 NCBI chr15:98,588,303...98,588,387 JBrowse link
G Mir708 microRNA 708 involved_in ISO (PMID:31599428) RGD PMID:31599428 NCBI chr 1:150,599,876...150,599,963 JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in ISO
IEA
(PMID:18511497)
GO_REF:0000107
RGD
Ensembl
PMID:18511497 GO_REF:0000107 NCBI chr10:84,224,599...84,231,812 JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (PMID:17395780) RGD PMID:17395780 NCBI chr13:43,121,168...43,147,581 JBrowse link
G Sqstm1 sequestosome 1 involved_in ISO (PMID:31281713) RGD PMID:31281713 NCBI chr10:35,026,598...35,037,750 JBrowse link
G Tax1bp1 Tax1 binding protein 1 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 4:81,821,991...81,877,906 JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 involved_in ISO (PMID:19412184) RGD PMID:19412184 NCBI chr18:41,481,057...41,498,065 JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29407460), (PMID:31134514) RGD PMID:29407460 PMID:31134514 NCBI chr 9:12,647,605...12,654,190 JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:28898289) RGD PMID:28898289 NCBI chr 5:79,005,139...79,016,615 JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO (PMID:19912257) RGD PMID:19912257 NCBI chr 1:15,528,921...15,543,993 JBrowse link
negative regulation of toll-like receptor 9 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gramd4 GRAM domain containing 4 involved_in IBA
ISO
GO_REF:0000033
(PMID:25917084)
GO_Central
RGD
PMID:25917084 GO_REF:0000033 NCBI chr 7:117,150,398...117,224,056 JBrowse link
G Ppt1 palmitoyl-protein thioesterase 1 involved_in ISO (PMID:14716310) RGD PMID:14716310 NCBI chr 5:135,121,164...135,142,048 JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISO
IEA
(PMID:26231120)
GO_REF:0000107
RGD
Ensembl
PMID:26231120 GO_REF:0000107 NCBI chr 9:1,245,408...1,307,015 JBrowse link
G Rab7b Rab7b, member RAS oncogene family involved_in ISO (PMID:19587007) RGD PMID:19587007 NCBI chr13:43,121,168...43,147,581 JBrowse link
negative regulation of toll-like receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:16378096)
Ensembl
RGD
PMID:16378096 GO_REF:0000107 NCBI chr10:55,645,539...55,653,485 JBrowse link
G Cactin cactin, spliceosome C complex subunit involved_in ISO (PMID:20829348) RGD PMID:20829348 NCBI chr 7:8,391,396...8,397,219 JBrowse link
G Gpr108 G protein-coupled receptor 108 involved_in ISS
IBA
ISO
IEA
GO_REF:0000024
GO_REF:0000033
(PMID:30332431)
GO_REF:0000107
UniProt
GO_Central
RGD
Ensembl
PMID:30332431 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:2,120,740...2,131,771 JBrowse link
G Gps2 G protein pathway suppressor 2 involved_in ISO (PMID:28039360) RGD PMID:28039360 NCBI chr10:54,637,360...54,640,542 JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (PMID:12150927) RGD PMID:12150927 NCBI chr 7:57,538,522...57,600,166 JBrowse link
G Irf4 interferon regulatory factor 4 acts_upstream_of_or_within ISO MGI:2387941 (PMID:16236719) RGD PMID:16236719 NCBI chr17:33,930,460...33,948,842 JBrowse link
G Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:23589304)
UniProt
RGD
PMID:23589304 GO_REF:0000024 NCBI chr 3:96,447,385...96,550,006 JBrowse link
G Lrrc14 leucine rich repeat containing 14 involved_in ISO
IBA
IEA
ISS
(PMID:27426725)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:27426725 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:108,430,755...108,437,118 JBrowse link
G Mir140 microRNA 140 IMP RGD PMID:31376096 RGD:329337378 NCBI chr19:52,375,293...52,375,391 JBrowse link
G Mir17 microRNA 17 involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,587,848...98,587,931 JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:26041742) RGD PMID:26041742 NCBI chr15:98,588,131...98,588,212 JBrowse link
G Nfkbil1 NFKB inhibitor like 1 involved_in ISO
IBA
ISS
(PMID:20829348)
GO_REF:0000033
GO_REF:0000024
RGD
GO_Central
UniProt
PMID:20829348 GO_REF:0000024 GO_REF:0000033 NCBI chr20:3,589,974...3,608,348 JBrowse link
G Nlrp6 NLR family, pyrin domain containing 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5085850 (PMID:22763455)
Ensembl
RGD
PMID:22763455 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245 JBrowse link
G Otud4 OTU deubiquitinase 4 involved_in ISO
IBA
(PMID:29395066)
GO_REF:0000033
RGD
GO_Central
PMID:29395066 GO_REF:0000033 NCBI chr19:28,236,713...28,279,815 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in IEA
ISO
GO_REF:0000107
(PMID:20584979)
Ensembl
RGD
PMID:20584979 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226 JBrowse link
G Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 involved_in ISO (PMID:20728433) RGD PMID:20728433 NCBI chr 1:250,040,250...250,194,364 JBrowse link
G Ptgs2os prostaglandin-endoperoxide synthase 2, opposite strand acts_upstream_of_or_within ISO (PMID:23907535) RGD PMID:23907535 NCBI chr13:62,160,002...62,163,710 JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) RGD PMID:35343654 NCBI chr 2:184,262,087...184,329,839 JBrowse link
G Smpdl3b sphingomyelin phosphodiesterase, acid-like 3B involved_in ISO (PMID:26095358) RGD PMID:26095358 NCBI chr 5:150,228,607...150,250,688 JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in ISS
ISO
IEA
GO_REF:0000024
UniProtKB:Q00993|UniProtKB:Q60805 (PMID:18083102)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18083102 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:127,231,468...127,254,806 JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon involved_in ISO (PMID:35343654) RGD PMID:35343654 NCBI chr10:61,082,934...61,120,618 JBrowse link
NLRP1 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp1a NLR family, pyrin domain containing 1A involved_in ISO (PMID:22665479), (PMID:27662089), (PMID:31484767), (PMID:33243852), (PMID:33420028), (PMID:33420033), (PMID:33852854), (PMID:35594856) RGD PMID:22665479 PMID:27662089 PMID:31484767 PMID:33243852 PMID:33420028 More... NCBI chr10:55,778,560...55,833,639 JBrowse link
NLRP3 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atat1 alpha tubulin acetyltransferase 1 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 NCBI chr20:2,844,595...2,857,809 JBrowse link
G Gkn2 gastrokine 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:32226647)
GO_REF:0000107
RGD
Ensembl
PMID:32226647 GO_REF:0000107 NCBI chr 4:119,778,326...119,824,366 JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:2180015 (PMID:28928055) RGD PMID:28928055 NCBI chr 4:177,240,692...177,246,548 JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:17483456), (PMID:23582325), (PMID:25686105), (PMID:27043286), (PMID:27432880), (PMID:28465465), (PMID:28656979), (PMID:28943315), (PMID:30487600), (PMID:31189953), (PMID:33231615), (PMID:34554188), (PMID:34615873), (PMID:35114687), (PMID:35254907), (PMID:35559676), (PMID:36442502), (PMID:39173637)
(PMID:23582325), (PMID:26173909), (PMID:27043286), (PMID:28465465), (PMID:28656979), (PMID:28716882), (PMID:28943315), (PMID:30487600), (PMID:34615873), (PMID:34861190)
MGI:5465108 (PMID:22753929)
UniProt
RGD
PMID:17483456 PMID:22753929 PMID:23582325 PMID:25686105 PMID:26173909 More... GO_REF:0000024 NCBI chr10:44,826,299...44,853,373 JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:27432880) RGD PMID:27432880 NCBI chr 1:192,032,124...192,033,419 JBrowse link
G Sirt2 sirtuin 2 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:23502856)
Ensembl
RGD
PMID:23502856 GO_REF:0000107 NCBI chr 1:93,181,472...93,204,499 JBrowse link
NLRP6 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlrp6 NLR family, pyrin domain containing 6 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:32424362), (PMID:34678144)
GO_REF:0000107
(PMID:30674671), (PMID:31932628), (PMID:34678144)
UniProt
RGD
Ensembl
PMID:30674671 PMID:31932628 PMID:32424362 PMID:34678144 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:205,434,484...205,441,245 JBrowse link
nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf34 ring finger protein 34 involved_in ISO
IEA
ISS
(PMID:25012219)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:25012219 GO_REF:0000024 GO_REF:0000107 NCBI chr12:33,703,655...33,724,606 JBrowse link
nucleotide-binding oligomerization domain containing 1 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO (PMID:11058605), (PMID:12791997), (PMID:12796777)
(PMID:27007849)
RGD PMID:11058605 PMID:12791997 PMID:12796777 PMID:27007849 NCBI chr 4:85,391,142...85,442,281 JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:29452636), (PMID:30279485)
MGI:2660793 (PMID:11894098)
RGD PMID:11894098 PMID:29452636 PMID:30279485 NCBI chr 5:29,630,806...29,662,804 JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:18261938)
Ensembl
RGD
PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in ISO
IEA
(PMID:29452636)
GO_REF:0000107
RGD
Ensembl
PMID:29452636 GO_REF:0000107 NCBI chr  X:125,756,107...125,803,979 JBrowse link
nucleotide-binding oligomerization domain containing 2 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:50,218,149...50,238,430 JBrowse link
G Irf5 interferon regulatory factor 5 involved_in ISO (PMID:22412986) RGD PMID:22412986 NCBI chr 4:59,092,914...59,104,596 JBrowse link
G Irgm immunity-related GTPase M involved_in ISO (PMID:25891078) RGD PMID:25891078 NCBI chr10:33,734,640...33,742,720 JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:31875558) RGD PMID:31875558 NCBI chr15:52,390,267...52,407,630 JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 6:78,593,844...78,597,307 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in
ISO (PMID:12527755)
(PMID:15692052), (PMID:27007849)
(PMID:23892723)
(PMID:12626759), (PMID:15044951), (PMID:17355968), (PMID:23806334), (PMID:31649195)
RGD PMID:12527755 PMID:12626759 PMID:15044951 PMID:15692052 PMID:17355968 More... NCBI chr19:34,555,832...34,596,281 JBrowse link
G Otulin OTU deubiquitinase with linear linkage specificity involved_in ISO (PMID:23806334) RGD PMID:23806334 NCBI chr 2:78,290,437...78,316,633 JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit acts_upstream_of_or_within ISO (PMID:12527755) RGD PMID:12527755 NCBI chr 1:212,354,336...212,364,815 JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 involved_in
acts_upstream_of_or_within
ISO (PMID:16824733), (PMID:17355968), (PMID:17562858), (PMID:23806334), (PMID:28545134), (PMID:29452636), (PMID:30026309), (PMID:30279485), (PMID:30478312)
(PMID:17947236)
MGI:2660793 (PMID:11894098)
RGD PMID:11894098 PMID:16824733 PMID:17355968 PMID:17562858 PMID:17947236 More... NCBI chr 5:29,630,806...29,662,804 JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of
IEA
ISO
GO_REF:0000107
(PMID:18261938)
Ensembl
RGD
PMID:18261938 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882 JBrowse link
G Xiap X-linked inhibitor of apoptosis involved_in IEA
ISO
ISS
GO_REF:0000107
(PMID:19667203), (PMID:22607974), (PMID:29452636)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:19667203 PMID:22607974 PMID:29452636 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:125,756,107...125,803,979 JBrowse link
pattern recognition receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cgas cyclic GMP-AMP synthase involved_in ISO (PMID:23258413) RGD PMID:23258413 NCBI chr 8:79,292,282...79,306,998 JBrowse link
G Clec4e C-type lectin domain family 4, member E involved_in ISO
ISS
(PMID:24101491)
GO_REF:0000024
RGD
UniProt
PMID:24101491 GO_REF:0000024 NCBI chr 4:158,292,624...158,298,607 JBrowse link
G Inava innate immunity activator involved_in ISO (PMID:28436939) RGD PMID:28436939 NCBI chr13:50,218,149...50,238,430 JBrowse link
G Lacc1 laccase domain containing 1 involved_in ISO (PMID:28593945), (PMID:31875558) RGD PMID:28593945 PMID:31875558 NCBI chr15:52,390,267...52,407,630 JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 involved_in ISO (PMID:31649195) RGD PMID:31649195 NCBI chr 4:85,391,142...85,442,281 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:31649195) RGD PMID:31649195 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Rnf144a ring finger protein 144A involved_in ISO (PMID:37955227) RGD PMID:37955227 NCBI chr 6:42,899,767...43,019,769 JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:23910378) RGD PMID:23910378 NCBI chr18:27,332,119...27,338,371 JBrowse link
positive regulation of activation of membrane attack complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA
ISO
GO_REF:0000107
(PMID:15611275)
Ensembl
RGD
PMID:15611275 GO_REF:0000107 NCBI chr 9:2,174,412...2,201,339 JBrowse link
positive regulation of acute inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19282305 RGD:2314677 NCBI chr 5:53,204,867...53,230,396 JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO
GO_REF:0000024
(PMID:26021615)
UniProt
RGD
PMID:26021615 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993 JBrowse link
positive regulation of adaptive immune memory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISO
IEA
(PMID:20237408)
GO_REF:0000107
RGD
Ensembl
PMID:20237408 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660 JBrowse link
positive regulation of adaptive immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:26041538)
UniProt
RGD
PMID:26041538 GO_REF:0000024 NCBI chr 5:53,897,792...53,918,873 JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (PMID:24310610) RGD PMID:24310610 NCBI chr 3:125,810,207...125,895,574 JBrowse link
G Fadd Fas associated via death domain involved_in ISS
ISO
GO_REF:0000024
(PMID:21876153)
UniProt
RGD
PMID:21876153 GO_REF:0000024 NCBI chr 1:209,169,245...209,175,423 JBrowse link
G Il6st interleukin 6 cytokine family signal transducer involved_in ISO (PMID:14764690) RGD PMID:14764690 NCBI chr 2:45,798,872...45,839,501 JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:22732093) RGD PMID:22732093 NCBI chr 1:192,032,124...192,033,419 JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3716944 (PMID:16227612)
GO_REF:0000033
RGD
GO_Central
PMID:16227612 GO_REF:0000033 NCBI chr  X:127,326,815...127,341,521 JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA
(PMID:21890893)
GO_REF:0000107
RGD
Ensembl
PMID:21890893 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000 JBrowse link
G Skap1 src kinase associated phosphoprotein 1 involved_in ISO
IEA
(PMID:12652296)
GO_REF:0000107
RGD
Ensembl
PMID:12652296 GO_REF:0000107 NCBI chr10:81,425,472...81,732,651 JBrowse link
positive regulation of AIM2 inflammasome complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gbp2 guanylate binding protein 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:25774715), (PMID:25774716)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:25774715 PMID:25774716 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:231,332,488...231,348,573 JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:25774715), (PMID:25774716) RGD PMID:25774715 PMID:25774716 NCBI chr 2:233,910,999...233,930,320 JBrowse link
positive regulation of antibacterial peptide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO (PMID:18167348) RGD PMID:18167348 NCBI chr19:34,555,832...34,596,281 JBrowse link
positive regulation of antibacterial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klk1c10 kallikrein 1-related peptidase C10 involved_in ISO (PMID:18714013) RGD PMID:18714013 NCBI chr 1:103,539,527...103,543,586 JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in ISO (PMID:17012259) RGD PMID:17012259 NCBI chr 1:94,296,574...94,304,768 JBrowse link
G Klk7 kallikrein-related peptidase 7 involved_in IEA
ISO
GO_REF:0000107
(PMID:17012259)
Ensembl
RGD
PMID:17012259 GO_REF:0000107 NCBI chr 1:94,267,170...94,271,361 JBrowse link
G Pgc progastricsin involved_in ISO (PMID:12759353) RGD PMID:12759353 NCBI chr 9:13,257,462...13,265,682 JBrowse link
positive regulation of antibody-dependent cellular cytotoxicity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,872,720...4,876,425 JBrowse link
positive regulation of antifungal innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pla2g5 phospholipase A2, group V involved_in ISS
ISO
GO_REF:0000024
(PMID:19342668)
UniProt
RGD
PMID:19342668 GO_REF:0000024 NCBI chr 5:151,041,339...151,109,433 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:30911105) RGD PMID:30911105 NCBI chr 3:77,059,744...77,093,730 JBrowse link
G Trim62 tripartite motif-containing 62 involved_in ISO (PMID:26488816) RGD PMID:26488816 NCBI chr 5:141,230,830...141,260,629 JBrowse link
positive regulation of antigen receptor-mediated signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISS
ISO
GO_REF:0000024
(PMID:8692271)
UniProt
RGD
PMID:8692271 GO_REF:0000024 NCBI chr13:49,596,193...49,708,283 JBrowse link
positive regulation of antimicrobial humoral response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acod1 aconitate decarboxylase 1 involved_in ISO (PMID:23610393) RGD PMID:23610393 NCBI chr15:79,871,819...79,881,101 JBrowse link
G Camp cathelicidin antimicrobial peptide IMP RGD PMID:18227173 RGD:438738460 NCBI chr 8:109,841,729...109,843,543 JBrowse link
positive regulation of antimicrobial peptide production term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A involved_in IEA
ISO
GO_REF:0000107
(PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107 NCBI chr 9:30,640,844...30,644,331 JBrowse link
G Il17f interleukin 17F involved_in IEA
ISO
GO_REF:0000107
(PMID:19144317)
Ensembl
RGD
PMID:19144317 GO_REF:0000107 NCBI chr 9:23,190,094...23,201,482 JBrowse link
positive regulation of B cell receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:23499492)
GO_REF:0000107
(PMID:20237408)
UniProt
RGD
Ensembl
PMID:20237408 PMID:23499492 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:198,235,861...198,251,660 JBrowse link
G Cmtm3 CKLF-like MARVEL transmembrane domain containing 3 acts_upstream_of_or_within ISO (PMID:15196959) RGD PMID:15196959 NCBI chr19:622,563...630,721 JBrowse link
G Foxp1 forkhead box P1 involved_in ISO (PMID:30111844) RGD PMID:30111844 NCBI chr 4:133,117,346...133,808,647 JBrowse link
G Mir18a microRNA 18a involved_in ISO (PMID:24169826) RGD PMID:24169826 NCBI chr15:98,587,984...98,588,079 JBrowse link
G Mir19a microRNA 19a involved_in ISO (PMID:24169826), (PMID:26017478) RGD PMID:24169826 PMID:26017478 NCBI chr15:98,588,131...98,588,212 JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:116,019,383...116,055,628 JBrowse link
G Prkch protein kinase C, eta involved_in ISO
ISS
(PMID:18780722)
GO_REF:0000024
RGD
UniProt
PMID:18780722 GO_REF:0000024 NCBI chr 6:98,027,830...98,226,486 JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO MGI:5642299 (PMID:25074919) RGD PMID:25074919 NCBI chr 9:54,836,841...54,960,325 JBrowse link
G Stap1 signal transducing adaptor family member 1 involved_in ISO
IBA
(PMID:10518561)
GO_REF:0000033
RGD
GO_Central
PMID:10518561 GO_REF:0000033 NCBI chr14:21,950,466...21,981,395 JBrowse link
positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:34,555,832...34,596,281 JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:55,789,180...55,793,216 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:63,907,018...63,930,224 JBrowse link
positive regulation of cGAS/STING signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btk Bruton tyrosine kinase involved_in ISO (PMID:25704810) RGD PMID:25704810 NCBI chr  X:102,016,070...102,055,448 JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 involved_in ISO (PMID:37832545) RGD PMID:37832545 NCBI chr 5:51,149,524...51,212,012 JBrowse link
G Rnf39 ring finger protein 39 involved_in ISO (PMID:39255680) RGD PMID:39255680 NCBI chr20:1,604,794...1,610,283 JBrowse link
G Slc19a1 solute carrier family 19 member 1 involved_in ISO (PMID:36745868) RGD PMID:36745868 NCBI chr20:11,584,410...11,602,429 JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 involved_in ISO (PMID:37832545) RGD PMID:37832545 NCBI chr 7:113,556,157...113,587,351 JBrowse link
G Zdhhc9 zinc finger DHHC-type palmitoyltransferase 9 involved_in ISO (PMID:37802025) RGD PMID:37802025 NCBI chr  X:127,352,340...127,388,245 JBrowse link
positive regulation of chronic inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO MGI:104798 (PMID:9834074) RGD PMID:9834074 NCBI chr20:3,622,291...3,625,852 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:104797 (PMID:9834074) RGD PMID:9834074 NCBI chr20:3,626,685...3,629,303 JBrowse link
positive regulation of complement activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta involved_in ISO RNAcentral:URS0000424278_9606 (PMID:29384235) RGD PMID:29384235 NCBI chr 3:137,030,200...137,036,581 JBrowse link
G Mbl2 mannose binding lectin 2 IDA RGD PMID:9920905 RGD:4889148 NCBI chr 1:237,429,873...237,465,567 JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:17070910) RGD PMID:17070910 NCBI chr10:81,102,043...81,114,815 JBrowse link
positive regulation of complement activation, classical pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) RGD PMID:30548312 NCBI chr 9:12,647,605...12,654,190 JBrowse link
positive regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:11714832) RGD PMID:11714832 NCBI chr 2:26,772,274...26,785,226 JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:16677249) RGD PMID:16677249 NCBI chr 1:182,451,108...182,459,701 JBrowse link
positive regulation of Fc receptor mediated stimulatory signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:16831868)
GO_REF:0000033
RGD
GO_Central
PMID:16831868 GO_REF:0000033 NCBI chr18:82,449,924...82,545,107 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IMP RGD PMID:16177098 RGD:1578516 NCBI chr 5:21,437,127...21,553,097 JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:Q64455 (PMID:18249142) RGD PMID:18249142 NCBI chr13:49,596,193...49,708,283 JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO UniProtKB:P06800 (PMID:18249142) RGD PMID:18249142 NCBI chr 3:76,405,917...76,561,842 JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IMP RGD PMID:18832707 RGD:9835043 NCBI chr 2:195,896,967...195,974,851 JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:18832707 RGD:9835043 NCBI chr 3:12,898,349...13,016,234 JBrowse link
positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:25568335) RGD PMID:25568335 NCBI chr 7:20,135,248...20,184,757 JBrowse link
positive regulation of germinal center formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964)
Ensembl
RGD
PMID:14607964 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283 JBrowse link
G RT1-DMa RT1 class II, locus DMa involved_in ISO (PMID:11714799) RGD PMID:11714799 NCBI chr20:4,708,932...4,712,335 JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C acts_upstream_of_or_within ISO MGI:2389403 (PMID:14557413) RGD PMID:14557413 NCBI chr 7:113,736,046...113,738,523 JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within ISO MGI:3038886 (PMID:14988498) RGD PMID:14988498 NCBI chr10:54,400,054...54,403,723 JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within ISO MGI:2387426 (PMID:14557413) RGD PMID:14557413 NCBI chr16:79,462,406...79,492,888 JBrowse link
positive regulation of humoral immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:10520991) RGD PMID:10520991 NCBI chr10:84,594,399...84,604,514 JBrowse link
G RT1-DMa RT1 class II, locus DMa involved_in ISO (PMID:11714799) RGD PMID:11714799 NCBI chr20:4,708,932...4,712,335 JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:19004505)
UniProt
RGD
PMID:19004505 GO_REF:0000024 NCBI chr12:26,327,161...26,334,126 JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in ISO (PMID:19004505) RGD PMID:19004505 NCBI chr17:59,005,649...59,012,202 JBrowse link
positive regulation of humoral immune response mediated by circulating immunoglobulin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer2 Fc epsilon receptor II acts_upstream_of_or_within ISO MGI:3583003 (PMID:8041705) RGD PMID:8041705 NCBI chr12:1,742,809...1,754,476 JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:11934565 RGD:2303774 NCBI chr 4:77,693,417...77,701,025 JBrowse link
G Hpx hemopexin acts_upstream_of_or_within ISO MGI:2447193 (PMID:18641331) RGD PMID:18641331 NCBI chr 1:169,344,647...169,352,155 JBrowse link
G Lta lymphotoxin alpha acts_upstream_of_or_within ISO MGI:104798 (PMID:9834074) RGD PMID:9834074 NCBI chr20:3,622,291...3,625,852 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:8566034) RGD PMID:8566034 NCBI chr13:49,596,193...49,708,283 JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO MGI:104797 (PMID:9834074) RGD PMID:9834074 NCBI chr20:3,626,685...3,629,303 JBrowse link
positive regulation of hypersensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:10520991) RGD PMID:10520991 NCBI chr10:84,594,399...84,604,514 JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:19016771 RGD:2313413 NCBI chr  X:140,164,341...140,176,057 JBrowse link
G Gsdme gasdermin E involved_in ISO (PMID:32188940) RGD PMID:32188940 NCBI chr 4:80,590,344...80,651,943 JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:22348394)
(PMID:21215706)
UniProt
GO_Central
RGD
PMID:21215706 PMID:22348394 GO_REF:0000024 GO_REF:0000033 NCBI chr11:91,559,087...91,573,982 JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS
IBA
GO_REF:0000024
GO_REF:0000033
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,039,371...78,049,353 JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of immunoglobulin mediated immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IBA
(PMID:16831868)
GO_REF:0000033
RGD
GO_Central
PMID:16831868 GO_REF:0000033 NCBI chr18:82,449,924...82,545,107 JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
(PMID:16831868)
GO_REF:0000033
RGD
GO_Central
PMID:16831868 GO_REF:0000033 NCBI chr 1:79,372,123...79,407,379 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) RGD PMID:12496423 NCBI chr13:76,256,654...76,280,133 JBrowse link
positive regulation of immunoglobulin production in mucosal tissue term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C10h17orf99 similar to human chromosome 17 open reading frame 99 involved_in ISO (PMID:28978694) RGD PMID:28978694 NCBI chr10:103,015,371...103,027,407 JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:9973465)
Ensembl
RGD
PMID:9973465 GO_REF:0000107 NCBI chr13:77,248,687...77,252,343 JBrowse link
positive regulation of inflammatory response to antigenic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:10791997), (PMID:15314074) RGD PMID:10791997 PMID:15314074 NCBI chr20:48,655,549...48,661,786 JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:10791997) RGD PMID:10791997 NCBI chr 9:62,166,324...62,194,674 JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:11046035)
UniProt
RGD
PMID:11046035 GO_REF:0000024 NCBI chr 1:198,235,861...198,251,660 JBrowse link
G Kars1 lysyl-tRNA synthetase 1 involved_in ISO (PMID:15851690) RGD PMID:15851690 NCBI chr19:56,867,096...56,886,151 JBrowse link
positive regulation of innate immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (PMID:20683884) RGD PMID:20683884 NCBI chr 1:204,206,206...204,218,988 JBrowse link
G Akirin2 akirin 2 involved_in ISS
ISO
IBA
GO_REF:0000024
(PMID:25107474)
GO_REF:0000033
UniProt
RGD
GO_Central
PMID:25107474 GO_REF:0000024 GO_REF:0000033 NCBI chr 5:53,897,792...53,918,873 JBrowse link
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:9,171,814...9,180,310 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A involved_in ISO (PMID:38016475) RGD PMID:38016475 NCBI chr 1:209,993,881...210,056,329 JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:28636595) RGD PMID:28636595 NCBI chr13:65,602,322...65,639,098 JBrowse link
G Ereg epiregulin involved_in ISS
ISO
GO_REF:0000024
(PMID:16182244)
UniProt
RGD
PMID:16182244 GO_REF:0000024 NCBI chr14:17,311,485...17,325,260 JBrowse link
G Fadd Fas associated via death domain involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:209,169,245...209,175,423 JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO (PMID:25505240) RGD PMID:25505240 NCBI chr 1:67,449,637...67,458,272 JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:233,910,999...233,930,320 JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO UniProtKB:O08573 (PMID:20937702) RGD PMID:20937702 NCBI chr10:31,383,801...31,415,334 JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:19890330) RGD PMID:19890330 NCBI chr12:11,009,236...11,015,941 JBrowse link
G Hmgb2 high mobility group box 2 involved_in ISO (PMID:19890330) RGD PMID:19890330 NCBI chr16:32,710,651...32,713,230 JBrowse link
G Ifi35 interferon-induced protein 35 involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr10:86,381,023...86,389,279 JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:32817552) RGD PMID:32817552 NCBI chr 1:202,895,751...202,903,178 JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q8VIM0 (PMID:20937702) RGD PMID:20937702 NCBI chr10:63,907,018...63,930,224 JBrowse link
G Nmi N-myc (and STAT) interactor involved_in ISO (PMID:29038465) RGD PMID:29038465 NCBI chr 3:56,824,778...56,848,891 JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in
ISO MGI:3529594 (PMID:15692051)
(PMID:21156799)
RGD PMID:15692051 PMID:21156799 NCBI chr19:34,555,832...34,596,281 JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15308695)
UniProt
RGD
PMID:15308695 GO_REF:0000024 NCBI chr 8:92,784,279...92,804,698 JBrowse link
G Polr3b RNA polymerase III subunit B involved_in ISO (PMID:19609254) RGD PMID:19609254 NCBI chr 7:19,039,179...19,142,450 JBrowse link
G Polr3c RNA polymerase III subunit C involved_in ISO
IEA
ISS
(PMID:19609254)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:19609254 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:184,246,201...184,262,150 JBrowse link
G Polr3d RNA polymerase III subunit D involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr15:45,511,587...45,516,256 JBrowse link
G Polr3f RNA polymerase III subunit F involved_in ISO (PMID:19631370) RGD PMID:19631370 NCBI chr 3:131,908,466...131,924,838 JBrowse link
G Polr3g RNA polymerase III subunit G involved_in ISO (PMID:19609254), (PMID:19631370) RGD PMID:19609254 PMID:19631370 NCBI chr 2:11,945,215...11,986,125 JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:24807708) RGD PMID:24807708 NCBI chr18:3,602,535...3,628,108 JBrowse link
G Rnf185 ring finger protein 185 involved_in ISO (PMID:28273161) RGD PMID:28273161 NCBI chr14:82,516,153...82,554,199 JBrowse link
G Slc15a4 solute carrier family 15 member 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:32433612)
UniProt
RGD
PMID:32433612 GO_REF:0000024 NCBI chr12:29,048,634...29,082,480 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in ISO (PMID:21531336) RGD PMID:21531336 NCBI chr10:45,507,152...45,529,164 JBrowse link
G Tasl TLR adaptor interacting with endolysosomal SLC15A4 involved_in ISO (PMID:32433612) RGD PMID:32433612 NCBI chr  X:54,354,755...54,373,930 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:16301656) RGD PMID:16301656 NCBI chr 8:41,789,557...41,805,903 JBrowse link
G Tlr8 toll-like receptor 8 involved_in ISO (PMID:16123302) RGD PMID:16123302 NCBI chr  X:27,091,780...27,116,092 JBrowse link
G Trim56 tripartite motif containing 56 involved_in ISO (PMID:29426904) RGD PMID:29426904 NCBI chr12:19,544,913...19,567,324 JBrowse link
G Zdhhc4 zinc finger DHHC-type palmitoyltransferase 4 involved_in ISO
IEA
(PMID:35606353)
GO_REF:0000107
RGD
Ensembl
PMID:35606353 GO_REF:0000107 NCBI chr12:11,230,864...11,244,898 JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) RGD PMID:12496423 NCBI chr13:76,256,654...76,280,133 JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr 5:59,573,849...59,579,065 JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr19:39,022,171...39,023,585 JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
GO_REF:0000024
(PMID:31806351)
UniProt
RGD
PMID:31806351 GO_REF:0000024 NCBI chr 4:120,392,812...120,415,616 JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
GO_REF:0000024
(PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 NCBI chr 1:201,000,444...201,049,819 JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISS
ISO
GO_REF:0000024
(PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 NCBI chr 1:78,128,325...78,135,931 JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:158,563,545...158,576,698 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) RGD PMID:20671152 NCBI chr 4:7,525,132...7,576,659 JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23306439), (PMID:23333305), (PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 NCBI chr 3:36,554,689...36,607,961 JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
GO_REF:0000033
RGD
GO_Central
PMID:29656893 GO_REF:0000033 NCBI chr 3:140,391,611...140,462,273 JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,544,940...9,640,323 JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO
IBA
(PMID:29656893)
GO_REF:0000033
RGD
GO_Central
PMID:29656893 GO_REF:0000033 NCBI chr 2:35,297,255...35,302,071 JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:26642240)
UniProt
RGD
PMID:26642240 GO_REF:0000024 NCBI chr11:81,668,478...81,690,318 JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(PMID:15077110), (PMID:15159415)
RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 NCBI chr 3:128,620,320...128,724,716 JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109 JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 6:6,813,793...6,872,960 JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) RGD PMID:23241889 NCBI chr14:76,833,179...76,911,304 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (PMID:10430621) RGD PMID:10430621 NCBI chr12:15,790,478...15,814,790 JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14988498)
AgBase
RGD
PMID:14988498 GO_REF:0000024 NCBI chr 1:90,324,312...90,340,627 JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000033
RGD
GO_Central
PMID:14988498 GO_REF:0000033 NCBI chr10:54,400,054...54,403,723 JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (PMID:12023368) RGD PMID:12023368 NCBI chr 1:201,507,763...201,517,607 JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:38,272,003...38,277,549 JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:65,365,505...65,382,825