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ONTOLOGY REPORT - ANNOTATIONS

Term:NADP binding
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Accession:GO:0050661 term browser browse the term
Definition:Binding to nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
Synonyms:exact_synonym: nicotinamide adenine dinucleotide phosphate binding
 related_synonym: NADP or NADPH binding


show annotations for term's descendants           Sort by:
NADP binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aspdh aspartate dehydrogenase domain containing enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:104,094,983...104,097,244
Ensembl chr 1:94,958,316...94,960,722 		JBrowse link
G Cat catalase enables ISO
IEA		 (PMID:10656833)
GO_REF:0000107		 RGD
Ensembl		 PMID:10656833 GO_REF:0000107 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Crym crystallin, mu enables ISO (PMID:17242435) RGD PMID:17242435 NCBI chr 1:183,991,752...184,006,923
Ensembl chr 1:174,560,416...174,575,633 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:208,444,434...208,460,408
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dhfr dihydrofolate reductase enables IDA
IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central
RGD		 PMID:3970530 GO_REF:0000002 GO_REF:0000033, RGD:2300196 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase enables IDA
IBA
ISO		 GO_REF:0000033
(PMID:11988088), (PMID:8373446)		 GO_Central
RGD		 PMID:8373446 PMID:11988088 PMID:7626590 PMID:8373446 GO_REF:0000033, RGD:1624989, RGD:8553278 NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G ENSRNOG00000066746 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 5:69,853,979...69,855,728 JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:77,715,405...77,747,666
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo13 flavin-containing monooxygenase 13 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:81,259,362...81,271,141
Ensembl chr13:78,726,398...78,738,178 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:77,755,131...77,777,597
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 enables IPI
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:17173378 GO_REF:0000002, RGD:1626480 NCBI chr13:77,838,899...77,868,869
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:77,687,909...77,706,100
Ensembl chr13:75,154,684...75,172,874 		JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:185,222,204...185,249,693 		JBrowse link
G Fmo6 flavin containing monooxygenase 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:77,793,600...77,821,958
Ensembl chr13:75,260,368...75,288,769 		JBrowse link
G Fmo9 flavin containing monooxygenase 9 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:81,353,044...81,374,033
Ensembl chr13:78,820,080...78,841,075 		JBrowse link
G Fmol flavin containing dimethylaniline monoxygenase like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:81,322,687...81,337,866
Ensembl chr13:78,790,856...78,804,900 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase enables IDA
IEA
ISO
IMP		 GO_REF:0000002
GO_REF:0000107
(PMID:15858258)		 InterPro
Ensembl
RGD		 PMID:15858258 PMID:17447164 PMID:16325866 GO_REF:0000002 GO_REF:0000107, RGD:1624966, RGD:1624987 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gapdh-ps118 Glyceraldehyde-3-phosphate dehydrogenase, pseudogene 118 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr18:61,626,988...61,628,224
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gapdhl10 glyceraldehyde-3-phosphate dehydrogenase like 10 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:15,370,290...15,371,300
Ensembl chr16:15,370,293...15,371,300 		JBrowse link
G Gapdhl3 glyceraldehyde-3-phosphate dehydrogenase like 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr15:77,324,675...77,471,131 JBrowse link
G Gapdhl6 glyceraldehyde-3-phosphate dehydrogenase like 6 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:75,960,507...75,968,953
Ensembl chr10:75,962,608...75,963,615 		JBrowse link
G Gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:95,106,516...95,125,918
Ensembl chr 1:85,979,098...85,993,640 		JBrowse link
G Glyr1 glyoxylate reductase 1 homolog enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:11,038,577...11,074,093
Ensembl chr10:10,532,154...10,567,637 		JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase IDA RGD PMID:2689175 RGD:1599320 NCBI chr 5:64,029,856...64,039,287
Ensembl chr 5:59,234,192...59,243,603 		JBrowse link
G Gsr glutathione-disulfide reductase enables IDA
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:237922 GO_REF:0000002, RGD:1625133 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) enables IDA
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:6813321 GO_REF:0000002, RGD:1641956 NCBI chr 5:165,717,456...165,753,158
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Hibadh 3-hydroxyisobutyrate dehydrogenase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:82,979,759...83,077,819
Ensembl chr 4:81,649,175...81,780,617 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 enables IDA
ISO		 (PMID:15513927), (PMID:17919905), (PMID:18069989), (PMID:18485702), (PMID:18553955), (PMID:19217779) RGD PMID:15513927 PMID:17919905 PMID:18069989 PMID:18485702 PMID:18553955 More... RGD:1625105 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 enables ISO
IEA		 (PMID:8805577)
GO_REF:0000107		 RGD
Ensembl		 PMID:8805577 GO_REF:0000107 NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 IDA RGD PMID:17447164 RGD:1624966 NCBI chr 9:74,027,887...74,057,442
Ensembl chr 9:66,534,146...66,563,708 		JBrowse link
G Kif1b kinesin family member 1B enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:164,890,778...165,025,848
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G LOC108352348 glyceraldehyde-3-phosphate dehydrogenase pseudogene enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr11:68,857,943...68,858,944 JBrowse link
G LOC134480667 glyceraldehyde-3-phosphate dehydrogenase-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002
G LOC134480898 glyceraldehyde-3-phosphate dehydrogenase-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr10:98,813,794...98,814,795 JBrowse link
G Me1 malic enzyme 1 IDA RGD PMID:17447164 RGD:1624966 NCBI chr 8:96,429,057...96,540,244
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Miox myo-inositol oxygenase IDA RGD PMID:10944187 RGD:631888 NCBI chr 7:122,284,660...122,287,158
Ensembl chr 7:120,405,031...120,407,537 		JBrowse link
G Mir100hgl Mir100 Mirlet7a-2 Mir125b-1 cluster host gene like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:41,943,334...41,986,943
Ensembl chr 8:41,950,987...41,961,199
Ensembl chr 8:41,950,987...41,961,199 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase IDA RGD PMID:11730351 RGD:1601423 NCBI chr 5:163,748,346...163,768,141
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO
IEA		 (PMID:15900210)
GO_REF:0000107
GO_REF:0000104		 RGD
Ensembl
UniProt		 PMID:15900210 GO_REF:0000104 GO_REF:0000107 NCBI chr 3:28,460,787...28,469,018
Ensembl chr 3:8,062,630...8,070,860 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase enables ISO
IEA
IBA		 (PMID:10673423)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10673423 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:53,144,157...53,237,857
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nos1 nitric oxide synthase 1 enables IDA
IEA		 PMID:17029414
GO_REF:0000002		 InterPro
RGD		 PMID:17029414 PMID:17029414 GO_REF:0000002, RGD:1598372, RGD:1598372 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pgd phosphogluconate dehydrogenase enables IDA
IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro
RGD		 PMID:17447164 PMID:6813321 GO_REF:0000002 GO_REF:0000033, RGD:1624966, RGD:1641956 NCBI chr 5:164,865,830...164,882,029
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Por cytochrome p450 oxidoreductase enables IDA
IEA
IMP		 GO_REF:0000104 UniProt
RGD		 PMID:9774150 PMID:16928691 GO_REF:0000104, RGD:1599688, RGD:1599694 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
NADP+ binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO		 GO_REF:0000107
(PMID:20124700)		 Ensembl
RGD		 PMID:20124700 GO_REF:0000107 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 enables IDA PMID:11839745 UniProt PMID:11839745 RGD:1304232 NCBI chr 5:156,876,721...156,884,599
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase enables ISO
IEA
ISS		 (PMID:9525924)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:9525924 GO_REF:0000024 GO_REF:0000107 NCBI chr17:32,304,029...32,830,708
Ensembl chr17:32,095,386...32,621,961 		JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 enables ISO
IEA		 (PMID:9525918)
GO_REF:0000107		 RGD
Ensembl		 PMID:9525918 GO_REF:0000107 NCBI chr10:86,510,011...86,512,211
Ensembl chr10:86,009,728...86,011,927 		JBrowse link
G Me3 malic enzyme 3 enables ISO
IEA		 (PMID:7818469)
GO_REF:0000107		 RGD
Ensembl		 PMID:7818469 GO_REF:0000107 NCBI chr 1:152,946,595...153,148,026
Ensembl chr 1:143,534,139...143,733,132 		JBrowse link
NADPH binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07068905.1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 8:817,915...819,124 JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 IDA RGD PMID:20709016 RGD:6903952 NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 enables IEA
ISO		 GO_REF:0000107
(PMID:20124700)		 Ensembl
RGD		 PMID:20124700 GO_REF:0000107 NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764 		JBrowse link
G Cbr3 carbonyl reductase 3 enables ISO
IEA		 (PMID:18493841)
GO_REF:0000107		 RGD
Ensembl		 PMID:18493841 GO_REF:0000107 NCBI chr11:46,478,295...46,486,555
Ensembl chr11:33,008,615...33,016,875 		JBrowse link
G Cbr4 carbonyl reductase 4 enables ISO
ISS
IEA		 (PMID:19000905), (PMID:25203508)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19000905 PMID:25203508 GO_REF:0000024 GO_REF:0000107 NCBI chr16:33,625,734...33,695,067
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Cryz crystallin zeta enables ISO
ISS
IBA		 (PMID:17497241)
GO_REF:0000024
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:17497241 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:246,211,707...246,239,472
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cybb cytochrome b-245 beta chain enables IEA
ISO		 GO_REF:0000107
(PMID:36413210), (PMID:38355798)		 Ensembl
RGD		 PMID:36413210 PMID:38355798 GO_REF:0000107 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 enables ISO
IEA		 (PMID:15531764)
GO_REF:0000107		 RGD
Ensembl		 PMID:15531764 GO_REF:0000107 NCBI chr 5:34,208,195...34,236,074
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Dhfr dihydrofolate reductase enables ISO (PMID:2303423) RGD PMID:2303423 NCBI chr 2:25,320,895...25,346,004
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dus2 dihydrouridine synthase 2 enables ISO (PMID:26429968) RGD PMID:26429968 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Grhpr glyoxylate and hydroxypyruvate reductase enables ISO
IEA		 (PMID:16756993)
GO_REF:0000107		 RGD
Ensembl		 PMID:16756993 GO_REF:0000107 NCBI chr 5:64,029,856...64,039,287
Ensembl chr 5:59,234,192...59,243,603 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase enables ISO
IEA		 (PMID:10698924)
GO_REF:0000107		 RGD
Ensembl		 PMID:10698924 GO_REF:0000107 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 enables ISO
ISS
IEA		 (PMID:17540341)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17540341 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:151,446,975...151,913,636
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Lbr lamin B receptor enables ISS
ISO
IEA		 GO_REF:0000024
(PMID:27336722)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:27336722 GO_REF:0000024 GO_REF:0000107 NCBI chr13:96,071,058...96,095,709
Ensembl chr13:93,538,920...93,564,017 		JBrowse link
G Mtrr 5-methyltetrahydrofolate-homocysteine methyltransferase reductase enables ISO (PMID:11466310) RGD PMID:11466310 NCBI chr 1:36,695,376...36,727,341
Ensembl chr 1:34,867,089...34,899,425 		JBrowse link
G Ndor1 NADPH dependent diflavin oxidoreductase 1 enables ISO
IEA		 (PMID:10625700)
GO_REF:0000107		 RGD
Ensembl		 PMID:10625700 GO_REF:0000107 NCBI chr 3:28,460,787...28,469,018
Ensembl chr 3:8,062,630...8,070,860 		JBrowse link
G Nos1 nitric oxide synthase 1 IDA RGD PMID:14966111 RGD:1358520 NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Qdpr quinoid dihydropteridine reductase enables IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:1639779 GO_REF:0000033, RGD:5128591 NCBI chr14:69,882,776...69,896,378
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IDA RGD PMID:11377984 RGD:4891997 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 enables ISO (PMID:19349281) RGD PMID:19349281 NCBI chr 6:33,537,779...33,545,204 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21102
    binding 18151
      nucleoside phosphate binding 2597
        nucleotide binding 2570
          purine nucleotide binding 2412
            adenyl nucleotide binding 1784
              NADP binding 65
                NADP+ binding 6
                NADPH binding 20
Path 2
Term Annotations click to browse term
  molecular_function 21102
    binding 18151
      small molecule binding 6652
        heterocyclic compound binding 2744
          nucleotide binding 2570
            purine nucleotide binding 2412
              adenyl nucleotide binding 1784
                NADP binding 65
                  NADP+ binding 6
                  NADPH binding 20
paths to the root