Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic active zone membrane
go back to main search page
Accession:GO:0048787 term browser browse the term
Definition:The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.
Synonyms:exact_synonym: active zone plasma membrane;   active zone pre-synaptic plasma membrane;   active zone presynaptic plasma membrane;   pre-synaptic active zone membrane
 xref: NIF_Subcellular:sao2038461087


show annotations for term's descendants           Sort by:
presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenoceptor alpha 2A is_active_in IDA PMID:9596526 SynGO PMID:9596526 RGD:13702430 NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Afdn afadin, adherens junction formation factor is_active_in ISO (PMID:11827984) RGD PMID:11827984 NCBI chr 1:53,905,344...54,034,216
Ensembl chr 1:53,905,373...54,034,216 		JBrowse link
G Apba1 amyloid beta precursor protein binding family A member 1 located_in
is_active_in		 IEA
ISO		 GO_REF:0000107
(PMID:10971649)		 Ensembl
RGD		 PMID:10971649 GO_REF:0000107 NCBI chr 1:221,363,769...221,569,496
Ensembl chr 1:221,363,778...221,566,553 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 is_active_in IDA
EXP		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr 7:35,622,267...35,731,904
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 is_active_in EXP
IDA		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 is_active_in IDA
EXP		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr13:47,708,157...47,807,389
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A is_active_in IDA
ISO		 PMID:22683683
(PMID:15090043)
PMID:25533484		 RGD PMID:15090043 PMID:22683683 PMID:25533484 RGD:13702208, RGD:405650228 NCBI chr19:40,425,560...40,724,810
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D is_active_in ISO (PMID:16354915) RGD PMID:16354915 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H is_active_in ISO (PMID:21358644) RGD PMID:21358644 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 is_active_in
located_in		 IDA
ISO
IEA		 PMID:19339603
(PMID:30683685)
GO_REF:0000107		 RGD
Ensembl		 PMID:30683685 PMID:19339603 GO_REF:0000107, RGD:13702164 NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 is_active_in
located_in		 ISO
IEA		 (PMID:30683685)
GO_REF:0000107		 RGD
Ensembl		 PMID:30683685 GO_REF:0000107 NCBI chr 8:116,950,860...117,082,159
Ensembl chr 8:108,072,454...108,203,173 		JBrowse link
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 is_active_in
located_in		 ISO
IEA		 (PMID:30683685)
GO_REF:0000107		 RGD
Ensembl		 PMID:30683685 GO_REF:0000107 NCBI chr16:4,105,048...4,919,037
Ensembl chr16:4,098,445...4,912,351 		JBrowse link
G Canx calnexin is_active_in EXP
IDA		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr10:35,124,941...35,157,954
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Cdh10 cadherin 10 is_active_in IDA PMID:29030434 SynGO PMID:29030434 RGD:13702213 NCBI chr 2:68,628,623...68,850,995
Ensembl chr 2:68,628,780...68,850,995 		JBrowse link
G Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 is_active_in ISO (PMID:34407949) RGD PMID:34407949 NCBI chr 8:109,530,597...109,558,360
Ensembl chr 8:109,530,641...109,558,354 		JBrowse link
G Cntnap2 contactin associated protein 2 is_active_in ISO (PMID:25707359) RGD PMID:25707359 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Cplx3 complexin 3 is_active_in ISO (PMID:15911881) RGD PMID:15911881 NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297 		JBrowse link
G Flot2 flotillin 2 is_active_in EXP
IDA		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr10:63,424,084...63,445,811
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Fzd3 frizzled class receptor 3 is_active_in ISO (PMID:34407949) RGD PMID:34407949 NCBI chr15:43,596,962...43,664,047
Ensembl chr15:39,421,355...39,488,369 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 is_active_in IDA PMID:11168550 SynGO PMID:11168550 RGD:155230774 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 is_active_in IDA PMID:12732237 SynGO PMID:12732237 RGD:13702456 NCBI chr  X:150,244,745...150,501,566
Ensembl chr  X:150,261,607...150,501,559 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 is_active_in IDA PMID:15174078 SynGO PMID:15174078 RGD:155230705 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 is_active_in IDA PMID:15174078 SynGO PMID:15174078 RGD:155230705 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gpm6a glycoprotein m6a is_active_in EXP
IDA		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 is_active_in IDA PMID:15610164 SynGO PMID:15610164 RGD:13702224 NCBI chr10:41,710,540...42,030,105
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 is_active_in IDA PMID:28057533 SynGO PMID:28057533 RGD:13702386 NCBI chr 2:168,247,490...168,367,616
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 is_active_in IDA PMID:12761821 SynGO PMID:12761821 RGD:13702231 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 is_active_in IDA PMID:15610164 SynGO PMID:15610164 RGD:13702224 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 is_active_in IDA PMID:23159309 SynGO PMID:23159309 RGD:13702288 NCBI chr 3:28,501,836...28,528,754
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B is_active_in IDA PMID:23159309 SynGO PMID:23159309 RGD:13702288 NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D is_active_in IDA PMID:23159309 SynGO PMID:23159309 RGD:13702288 NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B is_active_in IDA PMID:23159309 SynGO PMID:23159309 RGD:13702288 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183 		JBrowse link
G Grm4 glutamate metabotropic receptor 4 located_in
is_active_in		 IDA
ISO		 PMID:11906782
(PMID:11906782), (PMID:32494600)		 RGD PMID:11906782 PMID:32494600 PMID:11906782 RGD:8554275 NCBI chr20:5,486,024...5,574,668
Ensembl chr20:5,481,124...5,572,821 		JBrowse link
G Grm7 glutamate metabotropic receptor 7 is_active_in IDA
IMP		 PMID:9295396
PMID:35511883
PMID:12183395		 SynGO PMID:9295396 PMID:35511883 PMID:35511883 PMID:12183395 RGD:13702410, RGD:405650215, RGD:405650215, RGD:728478 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344 		JBrowse link
G Grm8 glutamate metabotropic receptor 8 is_active_in IDA PMID:9295396 SynGO PMID:9295396 RGD:13702410 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 is_active_in ISO (PMID:21358644) RGD PMID:21358644 NCBI chr 2:51,228,710...51,632,806
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Itga3 integrin subunit alpha 3 is_active_in ISO (PMID:28386022) RGD PMID:28386022 NCBI chr10:80,486,998...80,522,548
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 is_active_in IDA PMID:17883401 SynGO PMID:17883401 RGD:155230746 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 is_active_in IDA PMID:11739569 RGD
SynGO		 PMID:11739569 PMID:11739569 RGD:1581587, RGD:1581587 NCBI chr15:351,065...1,057,117
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 is_active_in ISO (PMID:33913808) RGD PMID:33913808 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Kctd12b potassium channel tetramerization domain containing 12b is_active_in ISO (PMID:33913808) RGD PMID:33913808 NCBI chr  X:17,643,707...17,654,820
Ensembl chr  X:17,643,615...17,654,820 		JBrowse link
G Kctd8 potassium channel tetramerization domain containing 8 is_active_in ISO (PMID:33913808) RGD PMID:33913808 NCBI chr14:38,773,274...39,018,182
Ensembl chr14:38,773,634...39,017,554 		JBrowse link
G Lpar2 lysophosphatidic acid receptor 2 is_active_in ISO (PMID:19766573) RGD PMID:19766573 NCBI chr16:19,592,067...19,599,998
Ensembl chr16:19,595,655...19,599,998 		JBrowse link
G Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 is_active_in IDA
IBA		 PMID:18227064
GO_REF:0000033		 GO_Central PMID:18227064 GO_REF:0000033, RGD:13702403 NCBI chr 1:85,616,862...85,623,725
Ensembl chr 1:85,616,868...85,623,725 		JBrowse link
G Napa NSF attachment protein alpha is_active_in IDA PMID:11718992 SynGO PMID:11718992 RGD:13702225 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869 		JBrowse link
G Napb NSF attachment protein beta is_active_in IDA PMID:11718992 SynGO PMID:11718992 RGD:13702225 NCBI chr 3:136,132,248...136,179,280
Ensembl chr 3:136,133,428...136,179,345 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 is_active_in ISO (PMID:11827984) RGD PMID:11827984 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787 		JBrowse link
G Nptn neuroplastin is_active_in IDA
EXP		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401 		JBrowse link
G Nrg1 neuregulin 1 is_active_in ISO (PMID:10686589) RGD PMID:10686589 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrxn1 neurexin 1 located_in
is_active_in		 IEA
ISO		 GO_REF:0000107
(PMID:17360903)		 Ensembl
RGD		 PMID:17360903 GO_REF:0000107 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Nrxn3 neurexin 3 located_in
is_active_in		 IEA
ISO		 GO_REF:0000107
(PMID:35550065)		 Ensembl
RGD		 PMID:35550065 GO_REF:0000107 NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Ntm neurotrimin is_active_in IDA PMID:12373100 SynGO PMID:12373100 RGD:2314481 NCBI chr 8:35,634,929...36,625,081
Ensembl chr 8:27,377,773...28,366,595 		JBrowse link
G Ntng1 netrin G1 is_active_in ISO (PMID:25411505) RGD PMID:25411505 NCBI chr 2:197,462,785...197,827,681
Ensembl chr 2:197,463,945...197,826,997 		JBrowse link
G Ntng2 netrin G2 is_active_in ISO (PMID:25411505) RGD PMID:25411505 NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890 		JBrowse link
G Otof otoferlin is_active_in
located_in		 IBA
ISO		 GO_REF:0000033
(PMID:25609709)		 GO_Central
RGD		 PMID:25609709 GO_REF:0000033 NCBI chr 6:25,928,018...26,024,631
Ensembl chr 6:25,928,055...26,024,631 		JBrowse link
G P2rx1 purinergic receptor P2X 1 is_active_in IDA
IEP		 PMID:16000618 SynGO PMID:16000618 PMID:16000618 RGD:1581702, RGD:1581702 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623 		JBrowse link
G P2rx2 purinergic receptor P2X 2 is_active_in IDA
IEP		 PMID:16000618 SynGO PMID:16000618 PMID:16000618 RGD:1581702, RGD:1581702 NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891 		JBrowse link
G P2ry1 purinergic receptor P2Y1 is_active_in IDA
IEP		 PMID:16000618 SynGO PMID:16000618 PMID:16000618 RGD:1581702, RGD:1581702 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry2 purinergic receptor P2Y2 is_active_in IDA
IEP		 PMID:16000618 SynGO PMID:16000618 PMID:16000618 RGD:1581702, RGD:1581702 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632 		JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 is_active_in IDA
IEP		 PMID:16000618 SynGO PMID:16000618 PMID:16000618 RGD:1581702, RGD:1581702 NCBI chr  X:65,681,680...65,717,404
Ensembl chr  X:65,683,232...65,721,748 		JBrowse link
G Ryk receptor-like tyrosine kinase is_active_in ISO (PMID:34407949) RGD PMID:34407949 NCBI chr 8:103,419,338...103,492,083
Ensembl chr 8:103,419,275...103,491,698 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 is_active_in IDA PMID:10779552 SynGO PMID:10779552 RGD:13702270 NCBI chr 7:131,982,152...132,156,075
Ensembl chr 7:131,982,480...132,151,292 		JBrowse link
G Snap91 synaptosome associated protein 91 IDA RGD PMID:15558718 RGD:1600759 NCBI chr 8:87,738,056...87,852,690
Ensembl chr 8:87,738,824...87,852,367 		JBrowse link
G Stx11 syntaxin 11 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164 		JBrowse link
G Stx1a syntaxin 1A is_active_in IDA PMID:26903802 SynGO PMID:26903802 RGD:12050133 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stx1b syntaxin 1B is_active_in
located_in		 ISO
IBA
IEA		 (PMID:23821748)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:23821748 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Stx2 syntaxin 2 is_active_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:27,678,744...27,714,751
Ensembl chr12:27,689,819...27,714,751 		JBrowse link
G Syt11 synaptotagmin 11 located_in
is_active_in		 IDA PMID:22960622 ParkinsonsUK-UCL
SynGO		 PMID:22960622 PMID:22960622 RGD:11079184, RGD:11079184 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Tenm3 teneurin transmembrane protein 3 is_active_in ISO (PMID:35484136) RGD PMID:35484136 NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 is_active_in EXP
IEP
IDA		 PMID:19187093 SynGO PMID:19187093 PMID:19187093 PMID:19187093 RGD:10003050, RGD:10003050, RGD:10003050 NCBI chr10:37,029,377...37,060,542
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
extrinsic component of presynaptic active zone membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dgki diacylglycerol kinase, iota is_active_in IDA PMID:21119615 SynGO PMID:21119615 RGD:8554416 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733 		JBrowse link
G Phb1 prohibitin 1 is_active_in IDA
EXP		 PMID:23622064 SynGO PMID:23622064 PMID:23622064 RGD:13702180, RGD:13702180 NCBI chr10:81,102,043...81,114,815
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 is_active_in ISO (PMID:29606581) RGD PMID:29606581 NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21329
    cellular anatomical structure 21034
      presynaptic active zone 137
        presynaptic active zone membrane 73
          extrinsic component of presynaptic active zone membrane 3
Path 2
Term Annotations click to browse term
  cellular_component 21329
    cellular anatomical structure 21034
      cell periphery 7085
        plasma membrane 6601
          plasma membrane region 1483
            synaptic membrane 586
              presynaptic membrane 272
                presynaptic active zone membrane 73
                  extrinsic component of presynaptic active zone membrane 3
paths to the root