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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of axon regeneration
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Accession:GO:0048681 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
Synonyms:exact_synonym: down regulation of axon regeneration;   downregulation of axon regeneration
 narrow_synonym: inhibition of axon regeneration



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negative regulation of axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cers2 ceramide synthase 2 involved_in IMP PMID:22393241 BHF-UCL PMID:22393241 RGD:11041067 NCBI chr 2:182,890,527...182,898,805
Ensembl chr 2:182,890,493...182,933,314
JBrowse link
G Epha4 Eph receptor A4 involved_in
NOT
IMP
ISO
ISS
(PMID:15537875)
GO_REF:0000024
RGD
UniProt
PMID:15537875 PMID:17970742 PMID:17418490 GO_REF:0000024, RGD:5688750, RGD:5688782 NCBI chr 9:86,263,982...86,406,744
Ensembl chr 9:78,815,460...78,958,139
JBrowse link
G Fignl2 fidgetin-like 2 involved_in IMP
IEA
PMID:33872220
GO_REF:0000107
Ensembl PMID:33872220 GO_REF:0000107, RGD:401901234 NCBI chr 7:132,160,006...132,187,896
Ensembl chr 7:132,162,390...132,164,336
JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F involved_in ISO
IEA
(PMID:26203138)
GO_REF:0000107
RGD
Ensembl
PMID:26203138 GO_REF:0000107 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:24167472)
Ensembl
RGD
PMID:24167472 GO_REF:0000107 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516
JBrowse link
G Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 acts_upstream_of_or_within ISO
IEA
(PMID:26651291)
GO_REF:0000107
RGD
Ensembl
PMID:26651291 GO_REF:0000107 NCBI chr 2:191,947,322...192,012,996
Ensembl chr 2:191,949,819...192,012,579
JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO
IEA
(PMID:26651291)
GO_REF:0000107
RGD
Ensembl
PMID:26651291 GO_REF:0000107 NCBI chr 8:59,273,860...59,426,486
Ensembl chr 8:59,275,569...59,430,348
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:26203138) RGD PMID:26203138 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptprs protein tyrosine phosphatase, receptor type, S involved_in ISS
ISO
GO_REF:0000024
(PMID:19780196), (PMID:22406547)
UniProt
RGD
PMID:19780196 PMID:22406547 GO_REF:0000024 NCBI chr 9:1,245,408...1,307,015
Ensembl chr 9:1,245,410...1,306,947
JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a IMP RGD PMID:16585268 RGD:9850138 NCBI chr 1:136,538,782...136,582,763
Ensembl chr 1:127,128,934...127,172,918
JBrowse link
G Rtn4r reticulon 4 receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:22406547)
UniProt
RGD
PMID:22406547 GO_REF:0000024 NCBI chr11:96,348,613...96,373,554
Ensembl chr11:82,844,309...82,869,466
JBrowse link
G Rtn4rl1 reticulon 4 receptor-like 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:22406547)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:22406547 GO_REF:0000024 GO_REF:0000107 NCBI chr10:60,541,584...60,615,302
Ensembl chr10:60,043,002...60,116,978
JBrowse link
G Xylt1 xylosyltransferase 1 IMP RGD PMID:18765417 RGD:2313145 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
negative regulation of axon extension involved in regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kiaa0319 KIAA0319 homolog acts_upstream_of_or_within ISO
IEA
(PMID:28334068)
GO_REF:0000107
MGI:4362922 (PMID:28334068)
RGD
Ensembl
PMID:28334068 GO_REF:0000107 NCBI chr17:40,162,512...40,226,666
Ensembl chr17:40,165,084...40,225,653
JBrowse link
G Tnr tenascin R acts_upstream_of_or_within ISO
IEA
MGI:2154583 (PMID:16870730)
GO_REF:0000107
RGD
Ensembl
PMID:16870730 GO_REF:0000107 NCBI chr13:74,285,141...74,706,174
Ensembl chr13:72,091,585...72,167,641
JBrowse link
negative regulation of collateral sprouting of intact axon in response to injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Spp1 secreted phosphoprotein 1 IEP RGD PMID:15625076 RGD:1581125 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
JBrowse link
negative regulation of optical nerve axon regeneration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rtca RNA 3'-terminal phosphate cyclase involved_in ISO
IEA
(PMID:31919191)
GO_REF:0000107
RGD
Ensembl
PMID:31919191 GO_REF:0000107 NCBI chr 2:204,455,175...204,476,450
Ensembl chr 2:204,455,175...204,476,460
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    response to stimulus 11082
      response to external stimulus 2809
        negative regulation of response to external stimulus 440
          negative regulation of axon regeneration 17
            negative regulation of collateral sprouting of intact axon in response to injury 1
            negative regulation of optical nerve axon regeneration 1
            negative regulation of sprouting of injured axon + 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            nervous system development 2881
              neurogenesis 2127
                generation of neurons 1821
                  neuron differentiation 1741
                    neuron development 1423
                      neuron projection development 1247
                        neuron projection regeneration 90
                          axon regeneration 76
                            regulation of axon regeneration 40
                              negative regulation of axon regeneration 17
                                negative regulation of collateral sprouting of intact axon in response to injury 1
                                negative regulation of optical nerve axon regeneration 1
                                negative regulation of sprouting of injured axon + 2
paths to the root