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ONTOLOGY REPORT - ANNOTATIONS


Term:sympathetic nervous system development
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Accession:GO:0048485 term browser browse the term
Definition:The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.



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sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in IEA
ISO
GO_REF:0000107
MGI:2687362 (PMID:25197047)
Ensembl
RGD
PMID:25197047 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961 JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 IMP RGD PMID:15496447 RGD:1358539 NCBI chr10:83,907,491...83,931,365 JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO MGI:2153826 (PMID:15329349) RGD PMID:15329349 NCBI chr17:68,643,760...68,666,000 JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:8657308)
Ensembl
UniProt
RGD
PMID:8657308 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242 JBrowse link
G Gfra3 GDNF family receptor alpha 3 acts_upstream_of_or_within ISO MGI:2136781|MGI:2183558 (PMID:10482239), (PMID:12160745) RGD PMID:10482239 PMID:12160745 NCBI chr18:26,571,952...26,600,225 JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16145670)
Ensembl
RGD
PMID:16145670 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488 JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
MGI:1857444 (PMID:16906226), (PMID:7926784)
HGNC-UCL
Ensembl
RGD
PMID:7926784 PMID:16906226 GO_REF:0000024 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086 JBrowse link
G Nrp1 neuropilin 1 acts_upstream_of_or_within ISO MGI:1857853 (PMID:15814794) RGD PMID:15814794 NCBI chr19:73,256,557...73,411,705 JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:8815902)
UniProt
RGD
PMID:8815902 GO_REF:0000024 NCBI chr 2:175,534,844...175,551,664 JBrowse link
G Phox2a paired-like homeobox 2a involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180328 (PMID:9115735)
Ensembl
RGD
PMID:9115735 GO_REF:0000107 NCBI chr 1:156,178,754...156,183,118 JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (PMID:10360575) RGD PMID:10360575 NCBI chr14:41,420,011...41,424,527 JBrowse link
G Plxna4 plexin A4 acts_upstream_of_or_within ISO MGI:3578655 (PMID:15814794) RGD PMID:15814794 NCBI chr 4:60,720,246...61,162,206 JBrowse link
G Sox11 SRY-box transcription factor 11 involved_in ISS
ISO
GO_REF:0000024
(PMID:20147379)
UniProt
RGD
PMID:20147379 GO_REF:0000024 NCBI chr 6:44,008,333...44,010,354 JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:20147379) RGD PMID:20147379 NCBI chr17:35,876,298...35,881,004 JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:104672 (PMID:21539825) RGD PMID:21539825 NCBI chr17:24,230,064...24,253,219 JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:104671 (PMID:21539825)
UniProt
RGD
PMID:21539825 GO_REF:0000024 NCBI chr 9:21,786,251...21,816,054 JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934580 (PMID:16337913) RGD PMID:16337913 NCBI chr11:88,343,647...88,554,543 JBrowse link
neural crest cell migration involved in sympathetic nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sema3a semaphorin 3A involved_in ISO (PMID:19325129) RGD PMID:19325129 NCBI chr 4:21,282,398...21,754,834 JBrowse link
sympathetic ganglion development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl1 achaete-scute family bHLH transcription factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18094025)
UniProt
RGD
PMID:18094025 GO_REF:0000024 NCBI chr 7:21,903,136...21,906,003 JBrowse link
G Ctnnb1 catenin beta 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:21325504)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:21325504 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661 JBrowse link
G Fzd3 frizzled class receptor 3 involved_in ISO (PMID:21325504) RGD PMID:21325504 NCBI chr15:39,421,366...39,488,369 JBrowse link
G Insm1 INSM transcriptional repressor 1 involved_in ISO (PMID:18094025) RGD PMID:18094025 NCBI chr 3:133,640,030...133,642,963 JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:19325129), (PMID:22790009) RGD PMID:19325129 PMID:22790009 NCBI chr19:73,256,557...73,411,705 JBrowse link
G Nrp2 neuropilin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:22790009)
Ensembl
RGD
PMID:22790009 GO_REF:0000107 NCBI chr 9:71,616,602...71,731,869 JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (PMID:18094025) RGD PMID:18094025 NCBI chr14:41,420,011...41,424,527 JBrowse link
G Sema3a semaphorin 3A involved_in ISO (PMID:22790009) RGD PMID:22790009 NCBI chr 4:21,282,398...21,754,834 JBrowse link
G Sema3f semaphorin 3F involved_in ISO (PMID:22790009) RGD PMID:22790009 NCBI chr 8:117,236,269...117,265,206 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    multicellular organismal process 8969
      multicellular organism development 5329
        system development 4611
          sympathetic nervous system development 24
            neural crest cell migration involved in sympathetic nervous system development 1
            sympathetic ganglion development 9
Path 2
Term Annotations click to browse term
  biological_process 20534
    developmental process 7107
      anatomical structure development 6609
        multicellular organism development 5329
          system development 4611
            nervous system development 2862
              autonomic nervous system development 51
                sympathetic nervous system development 24
                  neural crest cell migration involved in sympathetic nervous system development 1
                  sympathetic ganglion development 9
paths to the root