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ONTOLOGY REPORT - ANNOTATIONS


Term:enteric nervous system development
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Accession:GO:0048484 term browser browse the term
Definition:The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gallbladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.



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enteric nervous system development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednra endothelin receptor type A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:47,137,360...47,207,961 JBrowse link
G Ednrb endothelin receptor type B involved_in ISO (PMID:10021336) RGD PMID:10021336 NCBI chr15:87,055,490...87,086,765 JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:8657306), (PMID:8657308)
Ensembl
UniProt
RGD
PMID:8657306 PMID:8657308 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242 JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO MGI:2182089 (PMID:16854219) RGD PMID:16854219 NCBI chr13:96,280,335...96,285,750 JBrowse link
G Kif26a kinesin family member 26A involved_in ISO (PMID:19914172) RGD PMID:19914172 NCBI chr 6:131,214,839...131,250,874 JBrowse link
G Ntf3 neurotrophin 3 acts_upstream_of_or_within ISO MGI:1933844 (PMID:15497153) RGD PMID:15497153 NCBI chr 4:158,914,984...158,984,453 JBrowse link
G Phactr4 phosphatase and actin regulator 4 involved_in ISO (PMID:22215812) RGD PMID:22215812 NCBI chr 5:144,549,350...144,621,259 JBrowse link
G Phox2b paired-like homeobox 2b involved_in ISO (PMID:12640453)
(PMID:10360575)
RGD PMID:10360575 PMID:12640453 NCBI chr14:41,420,011...41,424,527 JBrowse link
G Ret ret proto-oncogene acts_upstream_of_or_within ISO MGI:2136894 (PMID:9834195) RGD PMID:9834195 NCBI chr 4:152,998,344...153,040,556 JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO (PMID:27111230) RGD PMID:27111230 NCBI chr10:62,322,688...62,357,060 JBrowse link
G Sox10 SRY-box transcription factor 10 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1857401|MGI:3701358 (PMID:16790476), (PMID:6512238)
(PMID:15572147)
GO_Central
RGD
PMID:6512238 PMID:15572147 PMID:16790476 GO_REF:0000033 NCBI chr 7:110,725,274...110,734,651 JBrowse link
G Sox8 SRY-box transcription factor 8 involved_in ISS
IBA
ISO
GO_REF:0000024
GO_REF:0000033
(PMID:15572147)
UniProt
GO_Central
RGD
PMID:15572147 GO_REF:0000024 GO_REF:0000033 NCBI chr10:14,584,829...14,589,818 JBrowse link
G Tlx2 T-cell leukemia homeobox 2 acts_upstream_of_or_within ISO MGI:2448951 (PMID:9259577) RGD PMID:9259577 NCBI chr 4:115,573,736...115,576,097 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    multicellular organismal process 8969
      multicellular organism development 5329
        system development 4611
          enteric nervous system development 13
Path 2
Term Annotations click to browse term
  biological_process 20534
    developmental process 7107
      anatomical structure development 6609
        multicellular organism development 5329
          system development 4611
            nervous system development 2862
              autonomic nervous system development 51
                enteric nervous system development 13
paths to the root