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ONTOLOGY REPORT - ANNOTATIONS
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Term:
L-glucuronate reductase activity
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Accession:
GO:0047939
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Definition:
Catalysis of the reaction: L-gulonate + NADP+ = D-glucuronate + H+ + NADPH.
Synonyms:
exact_synonym:
glucuronate reductase activity
narrow_synonym:
D-glucuronate reductase activity
related_synonym:
D-glucuronate dehydrogenase activity; NADP-L-gulonate dehydrogenase activity; TPN-L-gulonate dehydrogenase activity; aldehyde reductase II activity; glucuronate dehydrogenase activity
xref:
EC:1.1.1.19; KEGG_REACTION:R01481; MetaCyc:GLUCURONATE-REDUCTASE-RXN; RHEA:14909; reactome:R-HSA-5661256 "AKR1A1 reduces D-glucuronate to L-gulonate"
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Genes (2)
L-glucuronate reductase activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Akr1a1
aldo-keto reductase family 1 member A1
enables
IDA
ISO
PMID:22820017
(PMID:10510318), (PMID:30538128), (PMID:7669785)
MGI:4239556 (PMID:15769935), (PMID:20410296)
RGD
PMID:7669785
PMID:10510318
PMID:15769935
PMID:20410296
PMID:30538128
PMID:22820017
More...
RGD:13825440
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
G
Akr1b1
aldo-keto reductase family 1 member B1
enables
ISO
MGI:5008171 (PMID:20410296)
RGD
PMID:20410296
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
Term paths to the root
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Path 1
Term
Annotations
molecular_function
20633
catalytic activity
6032
oxidoreductase activity
854
oxidoreductase activity, acting on CH-OH group of donors
161
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
152
L-glucuronate reductase activity
2