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ONTOLOGY REPORT - ANNOTATIONS

Term:3-dehydrosphinganine reductase activity
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Accession:GO:0047560 term browser browse the term
Definition:Catalysis of the reaction: NADP+ + sphinganine = 3-dehydrosphinganine + H+ + NADPH.
Synonyms:related_synonym: 3-ketosphinganine reductase activity;   3-oxosphinganine reductase activity;   3-oxosphinganine:NADPH oxidoreductase activity;   D-3-dehydrosphinganine reductase activity;   D-3-oxosphinganine reductase activity;   D-3-oxosphinganine:B-NADPH oxidoreductase activity;   D-erythro-dihydrosphingosine:NADP+ 3-oxidoreductase activity;   DSR activity;   KTS reductase activity
 xref: EC:1.1.1.102;   KEGG_REACTION:R02978;   MetaCyc:3-DEHYDROSPHINGANINE-REDUCTASE-RXN;   RHEA:22640;   Reactome:R-HSA-428123 "KDSR reduces 3-ketosphingoid"


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3-dehydrosphinganine reductase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kdsr 3-ketodihydrosphingosine reductase enables ISO
IBA		 (PMID:15364918), (PMID:19141869), (PMID:28575652)
GO_REF:0000033		 RGD
GO_Central		 PMID:15364918 PMID:19141869 PMID:28575652 GO_REF:0000033 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
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  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            3-dehydrosphinganine reductase activity 1
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