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ONTOLOGY REPORT - ANNOTATIONS


Term:15-hydroxyprostaglandin dehydrogenase (NADP+) activity
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Accession:GO:0047021 term browser browse the term
Definition:Catalysis of the reaction: NADP+ + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H+ + NADPH.
Synonyms:broad_synonym: NADP-dependent 15-hydroxyprostaglandin dehydrogenase;   NADP-linked 15-hydroxyprostaglandin dehydrogenase;   NADP-specific 15-hydroxyprostaglandin dehydrogenase
 related_synonym: (13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity;   type II 15-hydroxyprostaglandin dehydrogenase activity
 xref: EC:1.1.1.197;   KEGG_REACTION:R04552;   MetaCyc:1.1.1.197-RXN;   RHEA:11636



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15-hydroxyprostaglandin dehydrogenase (NADP+) activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbr1 carbonyl reductase 1 enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
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  molecular_function 20633
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            15-hydroxyprostaglandin dehydrogenase (NADP+) activity 1
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