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ONTOLOGY REPORT - ANNOTATIONS

Term:cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
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Accession:GO:0047016 term browser browse the term
Definition:Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
Synonyms:broad_synonym: 3beta-hydroxy-delta5-C27-steroid oxidoreductase
 related_synonym: 3-beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase activity;   cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase activity;   cholest-5-ene-3beta,7alpha-diol:NAD+ 3-oxidoreductase activity
 xref: EC:1.1.1.181;   MetaCyc:1.1.1.181-RXN;   RHEA:11896


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cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 enables IDA
IEA
ISO		 GO_REF:0000107
(PMID:22999953)		 Ensembl
RGD		 PMID:22999953 PMID:16081591 GO_REF:0000107, RGD:1599972 NCBI chr 1:182,412,216...182,415,447
Ensembl chr 1:182,412,151...182,415,442 		JBrowse link
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  molecular_function 20633
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity 1
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