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ONTOLOGY REPORT - ANNOTATIONS


Term:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity
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Accession:GO:0047015 term browser browse the term
Definition:Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
Synonyms:related_synonym: (2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase activity;   2-methyl-3-hydroxy-butyryl CoA dehydrogenase activity;   2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase activity;   2-methyl-3-hydroxybutyryl-CoA dehydrogenase activity
 xref: EC:1.1.1.178;   MetaCyc:1.1.1.178-RXN;   RHEA:13281



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3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 enables ISS
ISO
IEA
GO_REF:0000024
(PMID:18996107), (PMID:19706438)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:18996107 PMID:19706438 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488
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  molecular_function 20634
    catalytic activity 6032
      oxidoreductase activity 854
        oxidoreductase activity, acting on CH-OH group of donors 161
          oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 152
            3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 1
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