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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of hemoglobin biosynthetic process
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Accession:GO:0046984 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
Synonyms:exact_synonym: regulation of haemoglobin biosynthesis;   regulation of haemoglobin biosynthetic process;   regulation of hemoglobin anabolism;   regulation of hemoglobin biosynthesis;   regulation of hemoglobin formation;   regulation of hemoglobin synthesis



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regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr12:15,824,431...15,858,266 JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:95513 (PMID:15931390) RGD PMID:15931390 NCBI chr18:57,945,123...57,978,327 JBrowse link
negative regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:11050009)
UniProt
Ensembl
RGD
PMID:11050009 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,824,431...15,858,266 JBrowse link
positive regulation of hemoglobin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb10 ATP binding cassette subfamily B member 10 involved_in ISO (PMID:22085049), (PMID:28808058) RGD PMID:22085049 PMID:28808058 NCBI chr19:51,952,655...51,982,910 JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO (PMID:21539536) RGD PMID:21539536 NCBI chr 5:75,074,107...75,079,182 JBrowse link
G Ldb1 LIM domain binding 1 involved_in ISO (PMID:20570862) RGD PMID:20570862 NCBI chr 1:244,864,168...244,890,007 JBrowse link
G Prmt1 protein arginine methyltransferase 1 involved_in IDA PMID:23483889 BHF-UCL PMID:23483889 RGD:10047341 NCBI chr 1:104,595,339...104,605,552 JBrowse link
G Slc25a37 solute carrier family 25 member 37 involved_in ISS
ISO
GO_REF:0000024
(PMID:19805291)
UniProt
RGD
PMID:19805291 GO_REF:0000024 NCBI chr15:50,944,085...50,986,506 JBrowse link
G Slc6a9 solute carrier family 6 member 9 involved_in ISO (PMID:28495915) RGD PMID:28495915 NCBI chr 5:136,660,022...136,694,173 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    cellular process 19523
      metabolic process 12157
        biosynthetic process 8641
          macromolecule biosynthetic process 7653
            regulation of macromolecule biosynthetic process 5425
              regulation of hemoglobin biosynthetic process 8
                negative regulation of hemoglobin biosynthetic process 1
                positive regulation of hemoglobin biosynthetic process 6
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of cellular process 13013
          regulation of metabolic process 6834
            regulation of primary metabolic process 5693
              regulation of protein metabolic process 2024
                regulation of hemoglobin biosynthetic process 8
                  negative regulation of hemoglobin biosynthetic process 1
                  positive regulation of hemoglobin biosynthetic process 6
paths to the root