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ONTOLOGY REPORT - ANNOTATIONS

Term:response to copper ion
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Accession:GO:0046688 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
Synonyms:exact_synonym: response to copper
 related_synonym: copper sensitivity/resistance


show annotations for term's descendants           Sort by:
response to copper ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase IDA RGD PMID:10451024 RGD:2301041 NCBI chr10:101,827,072...101,831,805
Ensembl chr10:101,827,301...101,831,801 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain IEP RGD PMID:10958805 RGD:1598689 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B IEP RGD PMID:11044632 RGD:1599065 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Atp7a ATPase copper transporting alpha IDA
IEP		 RGD PMID:17158254 PMID:15591161 RGD:1599385, RGD:1599393 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp7b ATPase copper transporting beta involved_in IEP
IEA
ISO		 GO_REF:0000107
(PMID:15269005), (PMID:16472602), (PMID:16939419)		 Ensembl
RGD		 PMID:15269005 PMID:16472602 PMID:16939419 PMID:15591161 GO_REF:0000107, RGD:1599393 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:18289470 RGD:2293024 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP RGD PMID:18289470 RGD:2293024 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 IEP RGD PMID:19497425 RGD:2316369 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cp ceruloplasmin IDA RGD PMID:19700037 RGD:2314683 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cycs cytochrome c, somatic IEP RGD PMID:14608045 RGD:11352711 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 IDA RGD PMID:3348368 RGD:2307322 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Dbh dopamine beta-hydroxylase IEP RGD PMID:19079842 RGD:5129530 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP RGD PMID:20544302 RGD:4145394 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1a interleukin 1 alpha involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12746488)		 Ensembl
UniProt
RGD		 PMID:12746488 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:24024382 RGD:12904019 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Lcat lecithin cholesterol acyltransferase IDA RGD PMID:7288494 RGD:1581777 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lipc lipase C, hepatic type IEP RGD PMID:3420106 RGD:2308778 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in ISO
ISS
IEA		 (PMID:23319596)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:23319596 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I IEP RGD PMID:18567746 RGD:2302302 NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP RGD PMID:10535524 RGD:2298958 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEP RGD PMID:17418555 RGD:1642079 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase IEP RGD PMID:15629125 RGD:2302420 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
G Prnp prion protein IDA RGD PMID:16148034 RGD:1599958 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G S100a13 S100 calcium binding protein A13 IEP RGD PMID:12754378 RGD:2316108 NCBI chr 2:175,999,439...176,005,933 JBrowse link
G Sod1 superoxide dismutase 1 IMP
IEP		 RGD PMID:14747682 PMID:12514262 RGD:1581098, RGD:634854 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod3 superoxide dismutase 3 IMP RGD PMID:16081273 RGD:1581097 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sord sorbitol dehydrogenase IDA RGD PMID:11044632 RGD:1599065 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Tfrc transferrin receptor IEP RGD PMID:17298691 RGD:2292032 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tk1 thymidine kinase 1 IEP RGD PMID:6642140 RGD:2317232 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
cellular response to copper ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein IEP RGD PMID:18583042 RGD:13782134 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp1 aquaporin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:7491270), (PMID:8584435)		 UniProt
RGD		 PMID:7491270 PMID:8584435 GO_REF:0000024 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp2 aquaporin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:8584435)		 Ensembl
RGD		 PMID:8584435 GO_REF:0000107 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Atp7a ATPase copper transporting alpha IEP
IDA		 RGD PMID:23174565 PMID:20671235 RGD:11341702, RGD:11341707 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp7b ATPase copper transporting beta IMP
IEP		 RGD PMID:24614235 PMID:24614235 RGD:11341682, RGD:11341682 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Bace1 beta-secretase 1 IEP RGD PMID:18583042 RGD:13782134 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Becn1 beclin 1 IEP RGD PMID:22540380 RGD:11561917 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP RGD PMID:24599699 RGD:11352816 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:24599699 RGD:11352816 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Daxx death-domain associated protein involved_in ISO
ISS
IEA		 (PMID:15016915)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:15016915 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Eln elastin IEP RGD PMID:18847363 RGD:9585685 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:15016915) RGD PMID:15016915 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:22540380 RGD:11561917 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Mt1 metallothionein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mt4 metallothionein 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO MGI:2385929 (PMID:24462598) RGD PMID:24462598 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within ISO MGI:2385925 (PMID:24462598) RGD PMID:24462598 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Prnp prion protein acts_upstream_of_or_within ISO (PMID:16254249) RGD PMID:16254249 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:21320589)
GO_REF:0000107		 RGD
Ensembl		 PMID:21320589 GO_REF:0000107 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP RGD PMID:19781568 RGD:5130971 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
detoxification of copper ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (PMID:7509170) RGD PMID:7509170 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Mt1 metallothionein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:97172|MGI:99400 (PMID:8640230)		 GO_Central
RGD		 PMID:8640230 GO_REF:0000033 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:97171|MGI:99400 (PMID:8640230)		 GO_Central
RGD		 PMID:8640230 GO_REF:0000033 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mt4 metallothionein 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:10,863,813...10,865,909
Ensembl chr19:10,863,813...10,865,909 		JBrowse link
G Muc2 mucin 2, oligomeric mucus/gel-forming involved_in ISS
ISO		 GO_REF:0000024
(PMID:36206754)		 UniProt
RGD		 PMID:36206754 GO_REF:0000024 NCBI chr 1:196,799,494...196,831,740
Ensembl chr 1:196,799,517...196,831,756 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:23792957)		 UniProt
RGD		 PMID:23792957 GO_REF:0000024 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    response to stimulus 11005
      response to chemical 5927
        response to metal ion 523
          response to copper ion 50
            cellular response to copper ion + 22
            stress response to copper ion + 7
paths to the root