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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of alpha-beta T cell activation
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Accession:GO:0046635 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.
Synonyms:exact_synonym: positive regulation of alpha-beta T lymphocyte activation;   up regulation of alpha-beta T cell activation;   upregulation of alpha-beta T cell activation
 narrow_synonym: activation of alpha-beta T cell activation;   stimulation of alpha-beta T cell activation


show annotations for term's descendants           Sort by:
positive regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-Bb RT1 class II, locus Bb involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd81 Cd81 molecule involved_in ISO
ISS		 (PMID:22307619)
GO_REF:0000024		 RGD
UniProt		 PMID:22307619 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:20639485)
GO_REF:0000107		 RGD
Ensembl		 PMID:20639485 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO
IEA		 (PMID:18193050)
GO_REF:0000107		 RGD
Ensembl		 PMID:18193050 GO_REF:0000107 NCBI chr 2:187,029,654...187,042,447
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO
IEA		 MGI:1857117 (PMID:11067867), (PMID:12163459), (PMID:16670300)
GO_REF:0000107		 RGD
Ensembl		 PMID:11067867 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO
IEA		 (PMID:15855276)
GO_REF:0000107		 RGD
Ensembl		 PMID:15855276 GO_REF:0000107 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO
IEA		 (PMID:19109233)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO
IEA		 MGI:3039799 (PMID:15064401)
GO_REF:0000107		 RGD
Ensembl		 PMID:15064401 GO_REF:0000107 NCBI chr13:94,601,072...94,696,180
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Nkap NFKB activating protein involved_in ISO
ISS		 (PMID:19409814)
GO_REF:0000024		 RGD
UniProt		 PMID:19409814 GO_REF:0000024 NCBI chr  X:121,238,714...121,258,360
Ensembl chr  X:116,372,839...116,394,945 		JBrowse link
G Pnp purine nucleoside phosphorylase acts_upstream_of_or_within ISO (PMID:16964310) RGD PMID:16964310 NCBI chr15:26,644,147...26,651,808
Ensembl chr15:24,170,602...24,203,986 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:25398325) RGD PMID:25398325 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:14764698)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:14764698 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO
IEA		 MGI:99613 (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:9275205 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO
IEA		 MGI:2677447|MGI:3526403|MGI:99515 (PMID:7630421), (PMID:9208839), (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
positive regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:3053044|MGI:3663359 (PMID:17210642) RGD PMID:17210642 NCBI chr 1:143,819,072...143,905,300
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:14662900)		 BHF-UCL
RGD		 PMID:14662900 GO_REF:0000024 NCBI chr 8:132,611,883...132,619,106
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:1346270), (PMID:1385153), (PMID:7908303), (PMID:9368605) RGD PMID:1346270 PMID:1385153 PMID:7908303 PMID:9368605 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd80 Cd80 molecule acts_upstream_of_or_within ISO (PMID:1385153) RGD PMID:1385153 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:7751624) RGD PMID:7751624 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within ISO
IEA		 MGI:99613 (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:9275205 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:16670306)
GO_REF:0000107		 RGD
Ensembl		 PMID:16670306 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO
IEA		 MGI:99515 (PMID:9275205)
GO_REF:0000107		 RGD
Ensembl		 PMID:9275205 GO_REF:0000107 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:38,989,750...39,011,700 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA		 (PMID:15265931)
GO_REF:0000107		 RGD
Ensembl		 PMID:15265931 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:15265931) RGD PMID:15265931 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:20639485)
GO_REF:0000107		 RGD
Ensembl		 PMID:20639485 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd83 CD83 molecule acts_upstream_of_or_within ISO MGI:3055293 (PMID:15322158) RGD PMID:15322158 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO
IEA		 (PMID:17028180)
GO_REF:0000107		 RGD
Ensembl		 PMID:17028180 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO		 GO_REF:0000024
(PMID:19015308)		 UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within ISO
IEA		 MGI:3716944 (PMID:16227612)
GO_REF:0000107		 RGD
Ensembl		 PMID:16227612 GO_REF:0000107 NCBI chr  X:132,204,717...132,219,421
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24880459)		 UniProt
RGD		 PMID:24880459 GO_REF:0000024 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:20639485)
GO_REF:0000107		 RGD
Ensembl		 PMID:20639485 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO
IEA		 (PMID:24880459)
GO_REF:0000107		 RGD
Ensembl		 PMID:24880459 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within ISO
IEA		 MGI:3039682 (PMID:12867038)
GO_REF:0000107		 RGD
Ensembl		 PMID:12867038 GO_REF:0000107 NCBI chr12:18,735,088...18,872,045
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:15314074), (PMID:8125140) RGD PMID:8125140 PMID:15314074 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:14973438), (PMID:8125140), (PMID:9368605) RGD PMID:8125140 PMID:9368605 PMID:14973438 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:11894097), (PMID:14973438), (PMID:8125140) RGD PMID:8125140 PMID:11894097 PMID:14973438 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) involved_in ISO (PMID:16818763) RGD PMID:16818763 NCBI chr13:44,409,574...44,438,913
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd81 Cd81 molecule involved_in ISO
ISS		 (PMID:22307619)
GO_REF:0000024		 RGD
UniProt		 PMID:22307619 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660 		JBrowse link
G Irgm immunity-related GTPase M involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18806793)		 UniProt
Ensembl
RGD		 PMID:18806793 GO_REF:0000024 GO_REF:0000107 NCBI chr10:33,734,640...33,742,720
Ensembl chr10:33,233,455...33,241,578 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:16116184) RGD PMID:16116184 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Prkcq protein kinase C, theta acts_upstream_of_or_within ISO
IEA		 MGI:2664379 (PMID:12867038)
GO_REF:0000107		 RGD
Ensembl		 PMID:12867038 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:2446070|MGI:2660793 (PMID:11894097), (PMID:11894098)
GO_REF:0000107		 RGD
Ensembl		 PMID:11894097 PMID:11894098 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:17164348)
GO_REF:0000107		 RGD
Ensembl		 PMID:17164348 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:9973465)		 Ensembl
RGD		 PMID:9973465 GO_REF:0000107 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO
IEA		 MGI:1857034|MGI:2654936|MGI:3696705 (PMID:12612578), (PMID:16275384), (PMID:16301745), (PMID:18573908)
GO_REF:0000107		 RGD
Ensembl		 PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15778366 RGD:2303772 NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO
IEA		 MGI:1857455 (PMID:16227984)
GO_REF:0000107		 RGD
Ensembl		 PMID:16227984 GO_REF:0000107 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO
IEA
ISS		 (PMID:34491895)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:34491895 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:139,134,655...139,159,898
Ensembl chr 1:129,722,026...129,750,227 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA		 (PMID:28467828)
GO_REF:0000107		 RGD
Ensembl		 PMID:28467828 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,512,911...4,518,455 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:28467828) RGD PMID:28467828 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:28676677) RGD PMID:28676677 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:24643698) RGD PMID:24643698 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO
IEA		 (PMID:18258917)
GO_REF:0000107		 RGD
Ensembl		 PMID:18258917 GO_REF:0000107 NCBI chr19:49,955,133...50,002,661
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO		 GO_REF:0000024
(PMID:19015308)		 UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18258917)		 UniProt
RGD		 PMID:18258917 GO_REF:0000024 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) RGD PMID:18258917 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (PMID:11739483) RGD PMID:11739483 NCBI chr13:86,583,727...86,606,902
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23871208) RGD PMID:23871208 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:25631937) RGD PMID:25631937 NCBI chr20:3,261,656...3,265,548
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
positive regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO (PMID:10201995), (PMID:11754812), (PMID:7538697) RGD PMID:7538697 PMID:10201995 PMID:11754812 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO MGI:1856989 (PMID:14557411) RGD PMID:14557411 NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within ISO
IEA		 MGI:1856083 (PMID:14557411)
GO_REF:0000107		 RGD
Ensembl		 PMID:14557411 GO_REF:0000107 NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:8,970,291...9,005,643 		JBrowse link
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO MGI:2180711|MGI:2180713 (PMID:10201995), (PMID:9133426) RGD PMID:9133426 PMID:10201995 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:172,423,582...172,427,089 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within ISO
IEA		 MGI:2183502|MGI:2386448 (PMID:16973387)
GO_REF:0000107		 RGD
Ensembl		 PMID:16973387 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:48,994,566...49,177,011 		JBrowse link
positive regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il12b interleukin 12B involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il18 interleukin 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19088061)		 Ensembl
RGD		 PMID:19088061 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO
IEA		 (PMID:19088061)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088061 GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Rasal3 RAS protein activator like 3 involved_in ISO
IEA		 (PMID:25652366)
GO_REF:0000107		 RGD
Ensembl		 PMID:25652366 GO_REF:0000107 NCBI chr 7:12,047,090...12,061,883
Ensembl chr 7:11,396,090...11,411,465 		JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 8:27,918,054...27,943,319
Ensembl chr 8:19,641,884...19,667,044 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17008549)		 UniProt
Ensembl
RGD		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) RGD PMID:15845453 NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO
IEA		 MGI:105367|MGI:2182089 (PMID:16424184)
GO_REF:0000107		 RGD
Ensembl		 PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:96,280,339...96,285,750 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:2446070 (PMID:11894097)
GO_REF:0000107		 RGD
Ensembl		 PMID:11894097 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in ISO
IEA		 (PMID:25282160)
GO_REF:0000107		 RGD
Ensembl		 PMID:25282160 GO_REF:0000107 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:58,942,299...58,994,260 		JBrowse link
G Mir326 microRNA 326 acts_upstream_of_or_within ISO (PMID:19838199) RGD PMID:19838199 NCBI chr 1:163,266,165...163,266,259
Ensembl chr 1:153,854,029...153,854,123 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO
IEA		 (PMID:26098997)
GO_REF:0000107		 RGD
Ensembl		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28262505)		 UniProt
Ensembl
RGD		 PMID:28262505 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,151...4,735,388 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:19501566)		 GO_Central
Ensembl
RGD		 PMID:19501566 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:721,809...723,923 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:36171294)		 UniProt
Ensembl
RGD		 PMID:36171294 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
positive regulation of T-helper 2 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcq protein kinase C, theta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:15263025)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:15263025 GO_REF:0000024 GO_REF:0000107 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:12496423)
GO_REF:0000107		 RGD
Ensembl		 PMID:12496423 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12829194)		 Ensembl
RGD		 PMID:12829194 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (PMID:16424184) RGD PMID:16424184 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) RGD PMID:12594267 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in ISO
IEA		 (PMID:26098997)
GO_REF:0000107		 RGD
Ensembl		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO		 GO_REF:0000024
(PMID:15987782)		 UniProt
RGD		 PMID:15987782 GO_REF:0000024 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO
IEA		 (PMID:18416830)
GO_REF:0000107		 RGD
Ensembl		 PMID:18416830 GO_REF:0000107 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:18354165)
GO_REF:0000107		 RGD
Ensembl		 PMID:18354165 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO
IEA		 MGI:3721903 (PMID:24645804)
GO_REF:0000107		 RGD
Ensembl		 PMID:24645804 GO_REF:0000107 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:59,678,216...59,785,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    immune system process 3130
      leukocyte activation 1082
        lymphocyte activation 875
          T cell activation 620
            alpha-beta T cell activation 214
              positive regulation of alpha-beta T cell activation 78
                positive regulation of CD4-positive, alpha-beta T cell activation + 46
                positive regulation of CD8-positive, alpha-beta T cell activation + 10
                positive regulation of NK T cell activation + 8
                positive regulation of alpha-beta T cell differentiation + 54
                positive regulation of alpha-beta T cell proliferation + 29
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of cellular process 13030
          regulation of cell activation 667
            regulation of leukocyte activation 609
              regulation of lymphocyte activation 525
                regulation of T cell activation 386
                  regulation of alpha-beta T cell activation 131
                    positive regulation of alpha-beta T cell activation 78
                      positive regulation of CD4-positive, alpha-beta T cell activation + 46
                      positive regulation of CD8-positive, alpha-beta T cell activation + 10
                      positive regulation of NK T cell activation + 8
                      positive regulation of alpha-beta T cell differentiation + 54
                      positive regulation of alpha-beta T cell proliferation + 29
paths to the root