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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of organ growth
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Accession:GO:0046621 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.


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negative regulation of organ growth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO MGI:3774418 (PMID:18162531) RGD PMID:18162531 NCBI chr 4:153,342,901...153,412,321
Ensembl chr 4:151,672,037...151,739,968 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide acts_upstream_of_or_within ISO MGI:1857152 (PMID:12114718) RGD PMID:12114718 NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Fxn frataxin acts_upstream_of_or_within ISO MGI:2177175|MGI:2177176 (PMID:9405681) RGD PMID:9405681 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Men1 menin 1 acts_upstream_of_or_within ISO (PMID:17975067) RGD PMID:17975067 NCBI chr 1:213,068,166...213,074,132
Ensembl chr 1:203,639,000...203,644,871 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:19208814) RGD PMID:19208814 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO MGI:87963 (PMID:16374517) RGD PMID:16374517 NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in ISO
IEA		 (PMID:19208814)
GO_REF:0000107		 RGD
Ensembl		 PMID:19208814 GO_REF:0000107 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of_or_within ISO MGI:1929004 (PMID:20080598) RGD PMID:20080598 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO
IEA		 MGI:1928487 (PMID:20080598)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080598 GO_REF:0000107 NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:17919533) RGD PMID:17919533 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Wwc1 WW and C2 domain containing 1 involved_in ISO
IBA		 (PMID:24682284)
GO_REF:0000033		 RGD
GO_Central		 PMID:24682284 GO_REF:0000033 NCBI chr10:20,804,173...20,958,437
Ensembl chr10:20,300,833...20,454,497 		JBrowse link
G Wwc2 WW and C2 domain containing 2 involved_in ISO
IEA
IBA		 (PMID:24682284)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:24682284 GO_REF:0000033 GO_REF:0000107 NCBI chr16:50,991,096...51,154,529
Ensembl chr16:44,258,372...44,421,812 		JBrowse link
G Wwc3 WWC family member 3 involved_in ISO
IEA
IBA		 (PMID:24682284)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:24682284 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:23,584,204...23,701,864
Ensembl chr  X:23,584,424...23,700,513 		JBrowse link
negative regulation of cardiac muscle cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway involved_in IMP PMID:28948298 BHF-UCL PMID:28948298 RGD:13464260 NCBI chr18:26,138,382...26,196,021
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in IMP PMID:26240138 BHF-UCL PMID:26240138 RGD:13210532 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cxadr CXADR, Ig-like cell adhesion molecule acts_upstream_of_or_within ISO MGI:3711226 (PMID:16543498) RGD PMID:16543498 NCBI chr11:30,469,778...30,516,990
Ensembl chr11:16,982,860...17,030,046 		JBrowse link
G Gja1 gap junction protein, alpha 1 IMP RGD PMID:19377854 RGD:7207421 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:3712002 (PMID:17322895) RGD PMID:17322895 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in
acts_upstream_of_or_within		 IMP
ISO
IDA		 PMID:26298346
MGI:1856923 (PMID:15870077)		 RGD PMID:15870077 PMID:26298346 PMID:26298346 RGD:11522645, RGD:11522645 NCBI chr17:19,983,217...20,163,598
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 IMP RGD PMID:24705172 RGD:9831164 NCBI chr13:103,297,387...103,494,686
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 acts_upstream_of_or_within ISO
IEA		 MGI:3609429 (PMID:21768366)
GO_REF:0000107		 RGD
Ensembl		 PMID:21768366 GO_REF:0000107 NCBI chr 7:122,098,120...122,105,023
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Mir1 microRNA 1 acts_upstream_of_or_within ISO (PMID:17397913) RGD PMID:17397913 NCBI chr18:2,160,327...2,160,413 JBrowse link
G Mir873 microRNA 873 involved_in ISO (PMID:28583401) RGD PMID:28583401 NCBI chr 5:56,153,104...56,153,180
Ensembl chr 5:51,356,919...51,356,995 		JBrowse link
G Nog noggin involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:17218603)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:17218603 GO_REF:0000024 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Pten phosphatase and tensin homolog involved_in IMP
ISO		 RNAcentral:URS000006FDD4_10090|RNAcentral:URS000013D17D_10090 (PMID:23575307) RGD PMID:23575307 PMID:30783439 RGD:150527846 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rbp4 retinol binding protein 4 involved_in ISO (PMID:12663486) RGD PMID:12663486 NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:235,893,917...235,901,399 		JBrowse link
G Sav1 salvador family WW domain containing protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:2654594|MGI:4430538 (PMID:21512031)
GO_REF:0000107		 RGD
Ensembl		 PMID:21512031 GO_REF:0000107 NCBI chr 6:94,214,514...94,236,354
Ensembl chr 6:88,478,539...88,499,968 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in ISO
IEA
ISS		 (PMID:11161571)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:11161571 GO_REF:0000024 GO_REF:0000107 NCBI chr12:42,342,926...42,399,723
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IMP RGD PMID:15537505 RGD:1601597 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO
IEA		 (PMID:18634800)
GO_REF:0000107		 RGD
Ensembl		 PMID:18634800 GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Vgll4 vestigial-like family member 4 involved_in ISO
IEA		 (PMID:27720608)
GO_REF:0000107		 RGD
Ensembl		 PMID:27720608 GO_REF:0000107 NCBI chr 4:147,925,630...148,038,519
Ensembl chr 4:147,927,034...148,038,471 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP RGD PMID:19358331 RGD:2312604 NCBI chr10:74,118,232...74,151,366
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:76,129,243...76,193,404
Ensembl chr18:73,854,282...73,916,457 		JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:133,117,346...133,808,647
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO (PMID:20516643) RGD PMID:20516643 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:63,459,569...63,459,640
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:161,522,399...161,637,623
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (PMID:17909105) RGD PMID:17909105 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:4,093,914...4,126,060
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:58,350,063...58,352,666
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:56,847,837...56,886,302
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (PMID:29065170) RGD PMID:29065170 NCBI chr 1:75,614,531...75,627,367
Ensembl chr 1:66,581,287...66,594,242 		JBrowse link
negative regulation of growth plate cartilage chondrocyte proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (PMID:26972716) RGD PMID:26972716 NCBI chr14:5,870,232...5,876,339
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    multicellular organismal process 9017
      negative regulation of multicellular organismal process 1367
        negative regulation of organ growth 47
          negative regulation of growth plate cartilage chondrocyte proliferation 1
          negative regulation of heart growth + 34
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of growth 686
          regulation of developmental growth 410
            regulation of organ growth 132
              negative regulation of organ growth 47
                negative regulation of growth plate cartilage chondrocyte proliferation 1
                negative regulation of heart growth + 34
paths to the root