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ONTOLOGY REPORT - ANNOTATIONS

Term:histamine N-methyltransferase activity
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Accession:GO:0046539 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H+.
Synonyms:related_synonym: S-adenosyl-L-methionine:histamine N-tele-methyltransferase activity;   S-adenosylmethionine-histamine N-methyltransferase activity;   histamine 1-methyltransferase activity;   histamine methyltransferase activity;   histamine-methylating enzyme;   imidazolemethyltransferase activity
 xref: EC:2.1.1.8;   KEGG_REACTION:R02155;   MetaCyc:HISTAMINE-N-METHYLTRANSFERASE-RXN;   RHEA:19301;   reactome:R-HSA-175993 "HNMT transfers CH3 group from AdoMet to Hist"


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histamine N-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnmt histamine N-methyltransferase enables IDA
ISO
IEA		 (PMID:26206890)
GO_REF:0000003
GO_REF:0000116		 RGD
UniProt
RHEA		 PMID:26206890 PMID:1639806 PMID:15739896 GO_REF:0000003 GO_REF:0000116, RGD:70763, RGD:152985534 NCBI chr 3:6,591,804...6,623,821
Ensembl chr 3:6,591,463...6,624,012 		JBrowse link
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Term Annotations click to browse term
  molecular_function 21100
    catalytic activity 6213
      transferase activity 2476
        transferase activity, transferring one-carbon groups 215
          methyltransferase activity 204
            S-adenosylmethionine-dependent methyltransferase activity 170
              histamine N-methyltransferase activity 1
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