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ONTOLOGY REPORT - ANNOTATIONS

Term:monosaccharide catabolic process
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Accession:GO:0046365 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms:exact_synonym: monosaccharide breakdown;   monosaccharide catabolism;   monosaccharide degradation

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canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A involved_in ISO (PMID:28049690) MGI PMID:28049690 NCBI chrNW_004936501:12,418,090...12,423,959
Ensembl chrNW_004936501:12,418,090...12,422,689 		JBrowse link
G Bcl2l13 BCL2 like 13 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936807:601,759...678,531
Ensembl chrNW_004936807:601,730...676,966 		JBrowse link
G Eno1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:3,115,357...3,130,289
Ensembl chrNW_004936623:3,115,081...3,128,183 		JBrowse link
G Eno2 enolase 2 involved_in ISO PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chrNW_004936709:904,647...913,445
Ensembl chrNW_004936709:904,031...913,451 		JBrowse link
G Eno3 enolase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:2,754,117...2,760,992
Ensembl chrNW_004936677:2,754,067...2,760,644 		JBrowse link
G Foxk1 forkhead box K1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936765:1,126,168...1,255,354
Ensembl chrNW_004936765:1,133,287...1,148,907 		JBrowse link
G Foxk2 forkhead box K2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936923:109,973...166,952
Ensembl chrNW_004936923:111,248...170,535 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:10777777), (PMID:28918937)
(PMID:12581789) 		MGI PMID:10777777 PMID:12581789 PMID:28918937 NCBI chrNW_004936709:1,243,149...1,247,782
Ensembl chrNW_004936709:1,243,147...1,247,903 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936570:1,582,120...1,608,537
Ensembl chrNW_004936570:1,579,372...1,608,788 		JBrowse link
G Hk1 hexokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:9,067,062...9,139,112
Ensembl chrNW_004936521:9,066,999...9,159,793 		JBrowse link
G Hk2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936556:1,054,143...1,113,425
Ensembl chrNW_004936556:1,054,021...1,113,450 		JBrowse link
G Pfkl phosphofructokinase, liver type involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936500:94,016...117,598
Ensembl chrNW_004936500:93,854...117,653 		JBrowse link
G Pfkm phosphofructokinase, muscle involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:19696889) TreeGrafter
MGI
Ensembl		 PMID:19696889 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936512:6,006,247...6,031,939
Ensembl chrNW_004936512:6,006,046...6,032,899 		JBrowse link
G Pfkp phosphofructokinase, platelet involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936484:11,105,814...11,161,238
Ensembl chrNW_004936484:11,103,142...11,161,344 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:2,240,452...2,248,689
Ensembl chrNW_004936636:2,236,508...2,248,768 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:19,021,928...19,026,110
Ensembl chrNW_004936478:19,020,048...19,024,394 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936547:286,267...310,062
Ensembl chrNW_004936547:286,267...310,062 		JBrowse link
G Pkm pyruvate kinase M1/2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:31,589,322...31,617,891
Ensembl chrNW_004936471:31,589,324...31,617,873 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:4275392) UniProt PMID:4275392 NCBI chrNW_004936561:3,826,802...3,844,406
Ensembl chrNW_004936561:3,825,787...3,844,483 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936709:948,151...951,430
Ensembl chrNW_004936709:945,201...951,441 		JBrowse link
D-ribose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt5 nudix hydrolase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:3,148,955...3,169,527
Ensembl chrNW_004936484:3,156,586...3,169,146 		JBrowse link
G Rbks ribokinase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004936493:4,768,444...4,853,273
Ensembl chrNW_004936493:4,768,528...4,853,273 		JBrowse link
D-xylose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhdh dihydrodiol dehydrogenase involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936664:2,955,538...2,964,709
Ensembl chrNW_004936664:2,955,479...2,964,784 		JBrowse link
fructose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 involved_in ISO (PMID:29414685), (PMID:4343087) MGI PMID:4343087 PMID:29414685 NCBI chrNW_004936503:8,869,073...8,953,726
Ensembl chrNW_004936503:8,868,961...8,918,532 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:9,584,302...9,592,961
Ensembl chrNW_004936524:9,584,140...9,596,276 		JBrowse link
G Glyctk glycerate kinase involved_in ISO (PMID:29414685) MGI PMID:29414685 NCBI chrNW_004936529:3,627,194...3,635,568
Ensembl chrNW_004936529:3,628,822...3,635,236 		JBrowse link
G Khk ketohexokinase involved_in ISO (PMID:23813872)
(PMID:4343087) 		MGI PMID:4343087 PMID:23813872 NCBI chrNW_004936493:5,444,284...5,455,100
Ensembl chrNW_004936493:5,441,165...5,455,176 		JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936524:9,584,302...9,592,961
Ensembl chrNW_004936524:9,584,140...9,596,276 		JBrowse link
G Khk ketohexokinase involved_in ISO (PMID:23813872), (PMID:24022321), (PMID:27465991) MGI PMID:23813872 PMID:24022321 PMID:27465991 NCBI chrNW_004936493:5,444,284...5,455,100
Ensembl chrNW_004936493:5,441,165...5,455,176 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936581:1,697,965...1,710,363
Ensembl chrNW_004936581:1,697,947...1,710,738 		JBrowse link
galactose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:8,949,814...8,954,269
Ensembl chrNW_004936474:8,949,798...8,954,315 		JBrowse link
G Glb1 galactosidase beta 1 ISO RGD PMID:6811372 RGD:1598981 NCBI chrNW_004936473:23,348,431...23,440,271
Ensembl chrNW_004936473:23,348,416...23,440,196 		JBrowse link
galactose catabolic process via UDP-galactose, Leloir pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:8,949,814...8,954,269
Ensembl chrNW_004936474:8,949,798...8,954,315 		JBrowse link
G Galk1 galactokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:944,936...950,537
Ensembl chrNW_004936594:944,944...949,838 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936524:2,726,795...2,730,049
Ensembl chrNW_004936524:2,726,749...2,730,564 		JBrowse link
G LOC101967464 galactose mutarotase-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004937892:5,117...17,831 JBrowse link
G LOC101967759 galactose mutarotase involved_in ISO (PMID:30451973) MGI PMID:30451973 NCBI chrNW_004936508:12,495,438...12,502,236 JBrowse link
G Pgm1 phosphoglucomutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936692:1,160,836...1,221,270
Ensembl chrNW_004936692:1,160,623...1,221,746 		JBrowse link
glucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:22998876 RGD:329412477 NCBI chrNW_004936481:18,274,158...18,330,136
Ensembl chrNW_004936481:18,274,154...18,330,173 		JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:4,924,349...4,933,683
Ensembl chrNW_004936599:4,924,789...4,933,368 		JBrowse link
G Gck glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936478:19,104,477...19,118,915
Ensembl chrNW_004936478:19,105,361...19,158,733 		JBrowse link
G Hk2 hexokinase 2 ISO RGD PMID:7948023 RGD:597805901 NCBI chrNW_004936556:1,054,143...1,113,425
Ensembl chrNW_004936556:1,054,021...1,113,450 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:1,746,309...1,814,471
Ensembl chrNW_004936599:1,746,406...1,814,321 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chrNW_004936557:5,559,993...5,584,912
Ensembl chrNW_004936557:5,560,746...5,585,192 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A acts_upstream_of_or_within ISO (PMID:8224816) MGI PMID:8224816 NCBI chrNW_004936528:866,607...879,977 JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936606:4,518,525...4,540,109
Ensembl chrNW_004936606:4,518,584...4,540,114 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425 		JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galk1 galactokinase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:944,936...950,537
Ensembl chrNW_004936594:944,944...949,838 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase acts_upstream_of_or_within ISO (PMID:11286504) MGI PMID:11286504 NCBI chrNW_004936524:2,726,795...2,730,049
Ensembl chrNW_004936524:2,726,749...2,730,564 		JBrowse link
L-fucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b14 hydroxysteroid 17-beta dehydrogenase 14 involved_in ISO (PMID:38944119) HGNC-UCL PMID:38944119
mannose to fructose-6-phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpi mannose phosphate isomerase acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:33,845,003...33,854,263
Ensembl chrNW_004936471:33,844,815...33,854,366 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chrNW_004936509:1,994,082...2,077,731
Ensembl chrNW_004936509:1,990,116...2,077,938 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936606:4,518,525...4,540,109
Ensembl chrNW_004936606:4,518,584...4,540,114 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:919,807...935,367
Ensembl chrNW_004936595:919,428...925,425 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,033,854...3,046,364
Ensembl chrNW_004936599:3,029,202...3,046,385 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17012
      metabolic process 11289
        catabolic process 2453
          small molecule catabolic process 332
            monosaccharide catabolic process 47
              1,5-anhydro-D-fructose catabolic process 0
              2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
              D-galacturonate catabolic process 0
              L-ascorbic acid catabolic process 0
              hexose catabolic process + 44
              pentose catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 17413
    cellular process 17012
      metabolic process 11289
        primary metabolic process 10018
          carbohydrate metabolic process 546
            monosaccharide metabolic process 260
              monosaccharide catabolic process 47
                1,5-anhydro-D-fructose catabolic process 0
                2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
                D-galacturonate catabolic process 0
                L-ascorbic acid catabolic process 0
                hexose catabolic process + 44
                pentose catabolic process + 3
paths to the root