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ONTOLOGY REPORT - ANNOTATIONS

Term:monosaccharide catabolic process
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Accession:GO:0046365 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms:exact_synonym: monosaccharide breakdown;   monosaccharide catabolism;   monosaccharide degradation

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canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldoa aldolase, fructose-bisphosphate A involved_in ISO (PMID:28049690) MGI PMID:28049690 NCBI chrNW_004624782:13,183,924...13,189,286 JBrowse link
G Bcl2l13 BCL2 like 13 acts_upstream_of_or_within ISO (PMID:31266807) MGI PMID:31266807 NCBI chrNW_004624735:9,594,134...9,692,967
Ensembl chrNW_004624735:9,599,383...9,687,277 		JBrowse link
G Eno1 enolase 1 involved_in ISO (PMID:3529090)
(PMID:29775581)
PMID:15041191 		CAFA
UniProt		 PMID:3529090 PMID:15041191 PMID:29775581 RGD:2302788 NCBI chrNW_004624818:3,223,384...3,235,128
Ensembl chrNW_004624818:3,223,308...3,238,419 		JBrowse link
G Eno2 enolase 2 involved_in ISO PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chrNW_004624860:3,553,936...3,561,343
Ensembl chrNW_004624860:3,553,947...3,564,294 		JBrowse link
G Eno3 enolase 3 involved_in ISO (PMID:27760309) MGI PMID:27760309 NCBI chrNW_004624786:8,807,498...8,813,561
Ensembl chrNW_004624786:8,807,450...8,813,951 		JBrowse link
G Foxk1 forkhead box K1 acts_upstream_of ISO (PMID:30700909) UniProt PMID:30700909 NCBI chrNW_004624740:28,533,708...28,585,880
Ensembl chrNW_004624740:28,538,745...28,585,886 		JBrowse link
G Foxk2 forkhead box K2 acts_upstream_of ISO (PMID:30700909) UniProt PMID:30700909 NCBI chrNW_004624801:11,260,838...11,303,656
Ensembl chrNW_004624801:11,260,836...11,304,773 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:10777777), (PMID:28918937)
(PMID:12581789) 		MGI PMID:10777777 PMID:12581789 PMID:28918937 NCBI chrNW_004624860:3,257,805...3,261,736
Ensembl chrNW_004624860:3,257,853...3,261,735 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO (PMID:8417789) MGI PMID:8417789 NCBI chrNW_004624794:8,826,281...8,851,614
Ensembl chrNW_004624794:8,823,449...8,851,625 		JBrowse link
G Hk1 hexokinase 1 involved_in ISO (PMID:4275392) MGI PMID:4275392 NCBI chrNW_004624754:3,594,478...3,656,231
Ensembl chrNW_004624754:3,591,090...3,659,760 		JBrowse link
G Hk2 hexokinase 2 involved_in ISO (PMID:29298880) UniProt PMID:29298880 NCBI chrNW_004624749:28,618,146...28,718,852
Ensembl chrNW_004624749:28,618,030...28,689,794 		JBrowse link
G Pfkl phosphofructokinase, liver type involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624745:29,826,202...29,842,859
Ensembl chrNW_004624745:29,823,317...29,842,881 		JBrowse link
G Pfkm phosphofructokinase, muscle acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:19696889) MGI
TreeGrafter		 PMID:19696889 GO_REF:0000118 NCBI chrNW_004624816:4,132,511...4,156,809
Ensembl chrNW_004624816:4,131,752...4,156,749 		JBrowse link
G Pfkp phosphofructokinase, platelet involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624775:7,325,032...7,390,200
Ensembl chrNW_004624775:7,324,662...7,390,271 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chrNW_004624737:9,088,545...9,096,350
Ensembl chrNW_004624737:9,088,539...9,096,348 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:7,947,738...7,949,900
Ensembl chrNW_004624740:7,947,742...7,950,956 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in ISO (PMID:30174313) MGI PMID:30174313 NCBI chrNW_004624836:2,657,320...2,676,124
Ensembl chrNW_004624836:2,653,474...2,676,766 		JBrowse link
G Pkm pyruvate kinase M1/2 involved_in ISO (PMID:28630053) MGI PMID:28630053 NCBI chrNW_004624781:1,796,909...1,823,787
Ensembl chrNW_004624781:1,796,801...1,824,144 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:4275392) UniProt PMID:4275392 NCBI chrNW_004624842:2,212,561...2,260,514
Ensembl chrNW_004624842:2,211,020...2,230,132 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in ISO (PMID:30174313) MGI PMID:30174313 NCBI chrNW_004624860:3,533,226...3,536,786
Ensembl chrNW_004624860:3,533,320...3,539,755 		JBrowse link
D-ribose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt5 nudix hydrolase 5 involved_in ISO (PMID:21389046) UniProt PMID:21389046 NCBI chrNW_004624805:4,903,250...4,922,719
Ensembl chrNW_004624805:4,903,373...4,915,846 		JBrowse link
G Rbks ribokinase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chrNW_004624738:9,795,381...9,911,276
Ensembl chrNW_004624738:9,806,933...9,910,684 		JBrowse link
D-xylose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhdh dihydrodiol dehydrogenase acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:6753830) MGI
TreeGrafter		 PMID:6753830 GO_REF:0000118 NCBI chrNW_004624832:5,064,859...5,070,148 JBrowse link
fructose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family member A1 involved_in ISO (PMID:29414685), (PMID:4343087) MGI PMID:4343087 PMID:29414685 NCBI chrNW_004624811:505,297...563,795
Ensembl chrNW_004624811:505,101...563,855 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B involved_in ISO (PMID:4343087)
(PMID:29533924) 		MGI PMID:4343087 PMID:29533924 NCBI chrNW_004624758:9,868,223...9,880,205
Ensembl chrNW_004624758:9,868,260...9,880,205 		JBrowse link
G Glyctk glycerate kinase involved_in ISO (PMID:29414685) MGI PMID:29414685 NCBI chrNW_004624730:6,088,702...6,095,621
Ensembl chrNW_004624730:6,089,167...6,099,660 		JBrowse link
G Khk ketohexokinase involved_in ISO (PMID:4343087)
(PMID:23813872) 		MGI PMID:4343087 PMID:23813872 NCBI chrNW_004624738:9,189,343...9,205,209
Ensembl chrNW_004624738:9,189,320...9,202,053 		JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in ISO (PMID:29533924) MGI PMID:29533924 NCBI chrNW_004624758:9,868,223...9,880,205
Ensembl chrNW_004624758:9,868,260...9,880,205 		JBrowse link
G Khk ketohexokinase involved_in ISO (PMID:23813872), (PMID:24022321), (PMID:27465991) MGI PMID:23813872 PMID:24022321 PMID:27465991 NCBI chrNW_004624738:9,189,343...9,205,209
Ensembl chrNW_004624738:9,189,320...9,202,053 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO (PMID:32818435) MGI PMID:32818435 NCBI chrNW_004624926:862,339...870,936
Ensembl chrNW_004624926:862,339...869,926 		JBrowse link
galactose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase involved_in ISO (PMID:16302980) UniProt PMID:16302980 NCBI chrNW_004624764:8,344,180...8,348,549
Ensembl chrNW_004624764:8,344,179...8,348,393 		JBrowse link
G Glb1 galactosidase beta 1 ISO RGD PMID:6811372 RGD:1598981 NCBI chrNW_004624788:10,970,657...11,110,839
Ensembl chrNW_004624788:10,970,652...11,111,722 		JBrowse link
galactose catabolic process via UDP-galactose, Leloir pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624764:8,344,180...8,348,549
Ensembl chrNW_004624764:8,344,179...8,348,393 		JBrowse link
G Galk1 galactokinase 1 involved_in ISO (PMID:10915771) MGI PMID:10915771 NCBI chrNW_004624801:5,646,112...5,649,822
Ensembl chrNW_004624801:5,646,239...5,650,214 		JBrowse link
G Galm galactose mutarotase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624738:20,164,179...20,236,151
Ensembl chrNW_004624738:20,163,901...20,235,256 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624736:39,040,139...39,043,449
Ensembl chrNW_004624736:39,040,009...39,043,444 		JBrowse link
G Pgm1 phosphoglucomutase 1 involved_in ISO (PMID:30982613) FlyBase PMID:30982613 NCBI chrNW_004624742:30,543,161...30,592,117
Ensembl chrNW_004624742:30,542,448...30,592,162 		JBrowse link
glucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 ISO RGD PMID:22998876 RGD:329412477 NCBI chrNW_004624826:5,844,868...5,897,541
Ensembl chrNW_004624826:5,845,001...5,897,497 		JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12931191) MGI PMID:12931191 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277 		JBrowse link
G Gck glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:7,844,496...7,885,900
Ensembl chrNW_004624740:7,852,390...7,886,758 		JBrowse link
G Hk2 hexokinase 2 ISO RGD PMID:7948023 RGD:597805901 NCBI chrNW_004624749:28,618,146...28,718,852
Ensembl chrNW_004624749:28,618,030...28,689,794 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO (PMID:19673927) BHF-UCL PMID:19673927 NCBI chrNW_004624767:18,438,165...18,551,362
Ensembl chrNW_004624767:18,438,274...18,551,338 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chrNW_004624807:4,420,577...4,442,842
Ensembl chrNW_004624807:4,420,047...4,443,370 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004624860:1,416,419...1,455,953
Ensembl chrNW_004624860:1,417,131...1,457,717 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004624786:10,266,316...10,282,664
Ensembl chrNW_004624786:10,263,518...10,271,218 		JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galk1 galactokinase 1 acts_upstream_of_or_within ISO (PMID:10915771) MGI PMID:10915771 NCBI chrNW_004624801:5,646,112...5,649,822
Ensembl chrNW_004624801:5,646,239...5,650,214 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase acts_upstream_of_or_within ISO (PMID:11286504) MGI PMID:11286504 NCBI chrNW_004624736:39,040,139...39,043,449
Ensembl chrNW_004624736:39,040,009...39,043,444 		JBrowse link
mannose to fructose-6-phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpi mannose phosphate isomerase involved_in
acts_upstream_of_or_within 		ISO (PMID:8307007)
(PMID:9525984)
(PMID:16339137) 		UniProt
FlyBase
MGI		 PMID:8307007 PMID:9525984 PMID:16339137 NCBI chrNW_004624894:84,508...96,598
Ensembl chrNW_004624894:87,355...93,965 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chrNW_004624787:9,187,450...9,319,684
Ensembl chrNW_004624787:9,184,514...9,320,060 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004624860:1,416,419...1,455,953
Ensembl chrNW_004624860:1,417,131...1,457,717 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (PMID:20935145) MGI PMID:20935145 NCBI chrNW_004624786:10,266,316...10,282,664
Ensembl chrNW_004624786:10,263,518...10,271,218 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (PMID:17828264) UniProt PMID:17828264 NCBI chrNW_004624767:19,844,996...19,859,274
Ensembl chrNW_004624767:19,844,884...19,858,950 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17646
    cellular process 17217
      metabolic process 10993
        catabolic process 2419
          small molecule catabolic process 324
            monosaccharide catabolic process 44
              1,5-anhydro-D-fructose catabolic process 0
              2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
              D-galacturonate catabolic process 0
              L-ascorbic acid catabolic process 0
              hexose catabolic process + 41
              pentose catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 17646
    cellular process 17217
      metabolic process 10993
        primary metabolic process 9826
          carbohydrate metabolic process 551
            monosaccharide metabolic process 257
              monosaccharide catabolic process 44
                1,5-anhydro-D-fructose catabolic process 0
                2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
                D-galacturonate catabolic process 0
                L-ascorbic acid catabolic process 0
                hexose catabolic process + 41
                pentose catabolic process + 3
paths to the root