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ONTOLOGY REPORT - ANNOTATIONS

Term:monosaccharide catabolic process
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Accession:GO:0046365 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms:exact_synonym: monosaccharide breakdown;   monosaccharide catabolism;   monosaccharide degradation

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canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L13 BCL2 like 13 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:122,884,846...122,902,669
Ensembl chr20:122,884,727...122,903,372 		JBrowse link
G ENO2 enolase 2 involved_in ISO PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chr11:6,945,243...6,954,959
Ensembl chr11:6,945,413...6,957,304 		JBrowse link
G ENO3 enolase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:4,431,321...4,439,742
Ensembl chr16:4,431,436...4,439,786 		JBrowse link
G FOXK1 forkhead box K1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr28:16,875,747...16,962,813
Ensembl chr28:16,880,884...16,962,734 		JBrowse link
G FOXK2 forkhead box K2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr16:74,426,111...74,506,453
Ensembl chr16:74,426,105...74,503,373 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:10777777), (PMID:28918937)
(PMID:12581789) 		MGI PMID:10777777 PMID:12581789 PMID:28918937 NCBI chr11:6,569,029...6,572,877 JBrowse link
G GPI glucose-6-phosphate isomerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,404,067...29,451,290
Ensembl chr 6:29,403,500...29,453,162 		JBrowse link
G HK1 hexokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:61,917,501...62,029,737
Ensembl chr 9:61,917,440...62,001,843 		JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:32,385,237...32,443,864
Ensembl chr14:32,385,249...32,442,403 		JBrowse link
G LOC103230584 uncharacterized LOC103230584 involved_in ISO (PMID:28049690) MGI PMID:28049690 NCBI chr 5:26,588,932...26,606,722
Ensembl chr 5:26,588,868...26,592,112 		JBrowse link
G PFKL phosphofructokinase, liver type involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:88,035,409...88,063,376
Ensembl chr 2:88,035,347...88,063,442 		JBrowse link
G PFKM phosphofructokinase, muscle acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:19696889) MGI
Ensembl
TreeGrafter		 PMID:19696889 GO_REF:0000107 GO_REF:0000118 NCBI chr11:44,332,857...44,378,273
Ensembl chr11:44,334,605...44,377,877 		JBrowse link
G PFKP phosphofructokinase, platelet involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:3,130,701...3,191,590
Ensembl chr 9:3,130,566...3,191,576 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) UniProt PMID:12189148 NCBI chr 9:90,581,593...90,585,054 JBrowse link
G PGAM2 phosphoglycerate mutase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:14,604,127...14,609,196
Ensembl chr21:14,606,401...14,609,158 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:30174313) MGI PMID:30174313 NCBI chr  X:67,072,029...67,093,881 JBrowse link
G PKM pyruvate kinase M1/2 involved_in ISO (PMID:28630053) MGI PMID:28630053 NCBI chr26:11,224,332...11,255,538 JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:4275392) UniProt PMID:4275392 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G TPI1 triosephosphate isomerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,900,762...6,904,188
Ensembl chr11:6,900,787...6,906,787 		JBrowse link
D-ribose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT5 nudix hydrolase 5 involved_in ISO (PMID:21389046) UniProt PMID:21389046 NCBI chr 9:12,218,466...12,247,129 JBrowse link
G NUDT5 nudix hydrolase 5 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:12,223,223...12,237,333 JBrowse link
G RBKS ribokinase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr14:79,733,144...79,847,074
Ensembl chr14:79,732,967...79,846,943 		JBrowse link
D-xylose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHDH dihydrodiol dehydrogenase involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:42,170,856...42,180,973
Ensembl chr 6:42,170,873...42,181,015 		JBrowse link
fructose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 involved_in ISO (PMID:29414685), (PMID:4343087) MGI PMID:4343087 PMID:29414685 NCBI chr12:83,949,529...84,092,452
Ensembl chr12:83,949,399...84,009,003 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258 		JBrowse link
G GLYCTK glycerate kinase involved_in ISO (PMID:29414685) MGI PMID:29414685 NCBI chr22:13,648,499...13,653,813
Ensembl chr22:13,651,024...13,653,801 		JBrowse link
G KHK ketohexokinase involved_in ISO (PMID:4343087)
(PMID:23813872) 		MGI PMID:4343087 PMID:23813872 NCBI chr14:80,518,049...80,531,643
Ensembl chr14:80,514,825...80,531,653 		JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:37,993,367...38,021,693
Ensembl chr12:38,007,265...38,021,258 		JBrowse link
G KHK ketohexokinase involved_in ISO (PMID:23813872), (PMID:24022321), (PMID:27465991) MGI PMID:23813872 PMID:24022321 PMID:27465991 NCBI chr14:80,518,049...80,531,643
Ensembl chr14:80,514,825...80,531,653 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:12,495,058...12,508,693
Ensembl chr 1:12,495,477...12,507,927 		JBrowse link
galactose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:108,883,796...108,889,917
Ensembl chr20:108,886,161...108,892,562 		JBrowse link
G GLB1 galactosidase beta 1 ISO RGD PMID:6811372 RGD:1598981 NCBI chr15:77,480,895...77,592,130
Ensembl chr15:77,480,598...77,592,120 		JBrowse link
galactose catabolic process via UDP-galactose, Leloir pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:108,883,796...108,889,917
Ensembl chr20:108,886,161...108,892,562 		JBrowse link
G GALK1 galactokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:45,919,316...45,926,423
Ensembl chr16:45,919,402...45,926,304 		JBrowse link
G GALM galactose mutarotase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:68,647,287...68,720,735
Ensembl chr14:68,647,297...68,720,739 		JBrowse link
G GALT galactose-1-phosphate uridylyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:45,970,655...45,974,669
Ensembl chr12:45,970,794...45,974,581 		JBrowse link
G PGM1 phosphoglucomutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:69,391,487...69,495,156
Ensembl chr20:69,428,996...69,466,191 		JBrowse link
glucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:22998876 RGD:329412477 NCBI chr25:61,129,837...61,228,180
Ensembl chr25:61,140,293...61,230,117 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G GCK glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:14,475,723...14,523,086
Ensembl chr21:14,507,902...14,523,850 		JBrowse link
G HK2 hexokinase 2 ISO RGD PMID:7948023 RGD:597805901 NCBI chr14:32,385,237...32,443,864
Ensembl chr14:32,385,249...32,442,403 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,090,048...6,224,956
Ensembl chr 1:6,089,930...6,190,383 		JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr25:22,277,692...22,306,057
Ensembl chr25:22,286,305...22,305,490 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDHA lactate dehydrogenase A acts_upstream_of_or_within ISO (PMID:8224816) MGI PMID:8224816 NCBI chr 1:46,525,090...46,542,587 JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr11:4,354,911...4,381,762
Ensembl chr11:4,355,053...4,381,273 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALK1 galactokinase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:45,919,316...45,926,423
Ensembl chr16:45,919,402...45,926,304 		JBrowse link
G GALT galactose-1-phosphate uridylyltransferase acts_upstream_of_or_within ISO (PMID:11286504) MGI PMID:11286504 NCBI chr12:45,970,655...45,974,669
Ensembl chr12:45,970,794...45,974,581 		JBrowse link
L-fucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 involved_in ISO (PMID:38944119) HGNC-UCL PMID:38944119 NCBI chr 6:42,052,330...42,075,843 JBrowse link
G HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:42,053,966...42,075,815 JBrowse link
mannose to fructose-6-phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPI mannose phosphate isomerase involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr26:8,574,135...8,582,575
Ensembl chr26:8,573,219...8,582,515 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr10:57,268,948...57,387,958
Ensembl chr10:57,265,550...57,387,910 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:4,354,911...4,381,762
Ensembl chr11:4,355,053...4,381,273 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,708,595...7,724,634
Ensembl chr 1:7,705,725...7,724,589 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      metabolic process 12971
        catabolic process 2581
          small molecule catabolic process 352
            monosaccharide catabolic process 48
              1,5-anhydro-D-fructose catabolic process 0
              2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
              D-galacturonate catabolic process 0
              L-ascorbic acid catabolic process 0
              hexose catabolic process + 44
              pentose catabolic process + 4
Path 2
Term Annotations click to browse term
  biological_process 19706
    cellular process 19211
      metabolic process 12971
        primary metabolic process 11397
          carbohydrate metabolic process 566
            monosaccharide metabolic process 271
              monosaccharide catabolic process 48
                1,5-anhydro-D-fructose catabolic process 0
                2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
                D-galacturonate catabolic process 0
                L-ascorbic acid catabolic process 0
                hexose catabolic process + 44
                pentose catabolic process + 4
paths to the root