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ONTOLOGY REPORT - ANNOTATIONS

Term:monosaccharide catabolic process
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Accession:GO:0046365 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms:exact_synonym: monosaccharide breakdown;   monosaccharide catabolism;   monosaccharide degradation


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canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L13 BCL2 like 13 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:1,069,082...1,161,771
Ensembl chr22:16,496,222...16,590,902 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G ENO2 enolase 2 involved_in ISO PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chr12:7,043,807...7,053,178
Ensembl chr12:6,958,960...6,968,342 		JBrowse link
G ENO3 enolase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,997,052...5,005,221
Ensembl chr17:4,986,116...4,992,876 		JBrowse link
G FOXK1 forkhead box K1 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 7:4,934,773...5,017,127
Ensembl chr 7:4,975,444...5,056,174 		JBrowse link
G FOXK2 forkhead box K2 acts_upstream_of ISO (PMID:30700909) UniProt PMID:30700909 NCBI chr17:76,930,135...77,018,294 JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:12581789)
(PMID:10777777), (PMID:28918937) 		MGI PMID:10777777 PMID:12581789 PMID:28918937 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729 		JBrowse link
G GPI glucose-6-phosphate isomerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,301,469...31,355,362
Ensembl chr19:40,024,584...40,080,598 		JBrowse link
G HK1 hexokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:65,786,940...65,870,204
Ensembl chr10:68,289,288...68,401,045 		JBrowse link
G HK2 hexokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,897,914...74,957,234
Ensembl chr2A:76,400,240...76,460,874 		JBrowse link
G LOC100980335 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:74,409,215...74,410,932 JBrowse link
G LOC100995352 keratin-associated protein 10-2 involved_in ISO (PMID:28049690) MGI PMID:28049690
G PFKL phosphofructokinase, liver type involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:30,557,576...30,584,231
Ensembl chr21:43,857,052...43,878,380 		JBrowse link
G PFKM phosphofructokinase, muscle involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:19696889) Ensembl
TreeGrafter
MGI		 PMID:19696889 GO_REF:0000107 GO_REF:0000118 NCBI chr12:40,584,321...40,625,245
Ensembl chr12:41,459,346...41,499,476 		JBrowse link
G PFKP phosphofructokinase, platelet involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:3,062,844...3,134,955
Ensembl chr10:3,080,242...3,244,790 		JBrowse link
G PGAM1 phosphoglycerate mutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:94,048,829...94,056,082
Ensembl chr10:97,542,558...97,549,867 		JBrowse link
G PGAM2 phosphoglycerate mutase 2 involved_in ISO (PMID:23951293) MGI PMID:23951293 NCBI chr 7:44,776,722...44,780,248
Ensembl chr 7:44,843,067...44,845,984 		JBrowse link
G PGK1 phosphoglycerate kinase 1 involved_in ISO (PMID:30174313) MGI PMID:30174313 NCBI chr  X:67,280,269...67,302,307
Ensembl chr  X:77,391,805...77,414,459 		JBrowse link
G PKM pyruvate kinase M1/2 involved_in ISO (PMID:28630053) MGI PMID:28630053 NCBI chr15:51,149,584...51,182,193
Ensembl chr15:69,913,455...69,945,832 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:4275392) UniProt PMID:4275392 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G TPI1 triosephosphate isomerase 1 involved_in ISO (PMID:30174313) MGI PMID:30174313 NCBI chr12:6,999,275...7,002,678
Ensembl chr12:6,910,813...6,913,612 		JBrowse link
D-ribose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NUDT5 nudix hydrolase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:12,177,922...12,206,435
Ensembl chr10:12,158,106...12,176,533 		JBrowse link
G RBKS ribokinase involved_in IEA UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr2A:27,779,074...27,886,586
Ensembl chr2A:27,863,731...27,970,949 		JBrowse link
D-xylose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHDH dihydrodiol dehydrogenase involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:45,934,740...45,946,051
Ensembl chr19:54,810,354...54,821,618 		JBrowse link
fructose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH1A1 aldehyde dehydrogenase 1 family member A1 involved_in ISO (PMID:29414685), (PMID:4343087) MGI PMID:4343087 PMID:29414685 NCBI chr 9:51,737,305...51,916,648
Ensembl chr 9:71,680,890...71,814,085 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:72,630,064...72,650,918
Ensembl chr 9:100,624,151...100,638,597 		JBrowse link
G GLYCTK glycerate kinase involved_in ISO (PMID:29414685) MGI PMID:29414685 NCBI chr 3:52,230,128...52,237,561
Ensembl chr 3:53,458,563...53,466,702 		JBrowse link
G KHK ketohexokinase involved_in ISO (PMID:4343087)
(PMID:23813872) 		MGI PMID:4343087 PMID:23813872 NCBI chr2A:27,085,758...27,099,768
Ensembl chr2A:27,174,896...27,189,308 		JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDOB aldolase, fructose-bisphosphate B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:72,630,064...72,650,918
Ensembl chr 9:100,624,151...100,638,597 		JBrowse link
G KHK ketohexokinase involved_in ISO (PMID:23813872), (PMID:24022321), (PMID:27465991) MGI PMID:23813872 PMID:24022321 PMID:27465991 NCBI chr2A:27,085,758...27,099,768
Ensembl chr2A:27,174,896...27,189,308 		JBrowse link
G TKFC triokinase and FMN cyclase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:56,633,046...56,648,276
Ensembl chr11:60,002,530...60,010,762 		JBrowse link
galactose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:22,987,218...22,992,416
Ensembl chr 1:23,971,454...23,976,500 		JBrowse link
G GLB1 galactosidase beta 1 ISO RGD PMID:6811372 RGD:1598981 NCBI chr 3:32,892,039...33,031,959
Ensembl chr 3:33,231,209...33,336,804 		JBrowse link
galactose catabolic process via UDP-galactose, Leloir pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALE UDP-galactose-4-epimerase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:22,987,218...22,992,416
Ensembl chr 1:23,971,454...23,976,500 		JBrowse link
G GALK1 galactokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:69,708,641...69,715,942
Ensembl chr17:75,259,522...75,269,048 		JBrowse link
G GALM galactose mutarotase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2A:38,697,338...38,770,470
Ensembl chr2A:39,456,786...39,527,116 		JBrowse link
G GALT galactose-1-phosphate uridylyltransferase involved_in IEA TreeGrafter GO_REF:0000118
G IL11RA interleukin 11 receptor subunit alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:34,487,313...34,498,477 JBrowse link
G PGM1 phosphoglucomutase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:62,849,451...62,916,359
Ensembl chr 1:64,658,599...64,725,496 		JBrowse link
glucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY10 adenylate cyclase 10 ISO RGD PMID:22998876 RGD:329412477 NCBI chr 1:143,239,576...143,404,038
Ensembl chr 1:147,023,671...147,129,705 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G GCK glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751 		JBrowse link
G HK2 hexokinase 2 ISO RGD PMID:7948023 RGD:597805901 NCBI chr2A:74,897,914...74,957,234
Ensembl chr2A:76,400,240...76,460,874 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817 		JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr 1:182,655,487...182,683,881
Ensembl chr 1:186,934,446...186,961,995 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDHA lactate dehydrogenase A acts_upstream_of_or_within ISO (PMID:8224816) MGI PMID:8224816 NCBI chr11:18,432,347...18,445,694
Ensembl chr11:18,115,250...18,128,400 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GALK1 galactokinase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:69,708,641...69,715,942
Ensembl chr17:75,259,522...75,269,048 		JBrowse link
G GALT galactose-1-phosphate uridylyltransferase acts_upstream_of_or_within ISO (PMID:11286504) MGI PMID:11286504
L-fucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD17B14 hydroxysteroid 17-beta dehydrogenase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,812,558...45,837,292
Ensembl chr19:54,918,606...54,942,676 		JBrowse link
mannose to fructose-6-phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MPI mannose phosphate isomerase acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chr15:53,832,088...53,841,832
Ensembl chr15:73,449,439...73,457,205 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:4,429,945...4,462,142
Ensembl chr12:4,353,272...4,385,380 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTN3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,905,722...61,922,227
Ensembl chr11:65,228,713...65,245,429 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      metabolic process 12795
        catabolic process 2514
          small molecule catabolic process 351
            monosaccharide catabolic process 48
              1,5-anhydro-D-fructose catabolic process 0
              2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
              D-galacturonate catabolic process 0
              L-ascorbic acid catabolic process 0
              hexose catabolic process + 45
              pentose catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      metabolic process 12795
        primary metabolic process 11190
          carbohydrate metabolic process 566
            monosaccharide metabolic process 264
              monosaccharide catabolic process 48
                1,5-anhydro-D-fructose catabolic process 0
                2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
                D-galacturonate catabolic process 0
                L-ascorbic acid catabolic process 0
                hexose catabolic process + 45
                pentose catabolic process + 3
paths to the root