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ONTOLOGY REPORT - ANNOTATIONS

Term:monosaccharide catabolic process
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Accession:GO:0046365 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
Synonyms:exact_synonym: monosaccharide breakdown;   monosaccharide catabolism;   monosaccharide degradation


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canonical glycolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l13 Bcl2-like 13 acts_upstream_of_or_within ISO
IEA		 (PMID:31266807)
GO_REF:0000107		 RGD
Ensembl		 PMID:31266807 GO_REF:0000107 NCBI chr 4:155,728,284...155,785,058
Ensembl chr 4:154,056,127...154,108,985 		JBrowse link
G Eno1 enolase 1 involved_in ISO
IDA		 (PMID:29775581), (PMID:3529090)
PMID:15041191		 RGD PMID:3529090 PMID:29775581 PMID:15041191 RGD:2302788 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Eno2 enolase 2 involved_in IDA PMID:15041191 CAFA PMID:15041191 RGD:2302788 NCBI chr 4:159,258,371...159,267,220
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eno3 enolase 3 involved_in ISO MGI:1196256 (PMID:27760309) RGD PMID:27760309 NCBI chr10:55,868,880...55,876,099
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Foxk1 forkhead box K1 acts_upstream_of ISO
IEA		 (PMID:30700909)
GO_REF:0000107		 RGD
Ensembl		 PMID:30700909 GO_REF:0000107 NCBI chr12:17,223,599...17,288,564
Ensembl chr12:12,115,950...12,175,089 		JBrowse link
G Foxk2 forkhead box K2 acts_upstream_of ISO (PMID:30700909) RGD PMID:30700909 NCBI chr10:107,040,933...107,090,860
Ensembl chr10:106,542,566...106,592,563 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:10777777), (PMID:12581789), (PMID:28918937) RGD PMID:10777777 PMID:12581789 PMID:28918937 NCBI chr 4:159,648,592...159,653,436
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gpi glucose-6-phosphate isomerase involved_in ISO
IEA		 (PMID:8417789)
GO_REF:0000107		 RGD
Ensembl		 PMID:8417789 GO_REF:0000107 NCBI chr 1:95,965,389...95,996,932
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Hk1 hexokinase 1 involved_in ISO
IEA		 (PMID:4275392)
GO_REF:0000107		 RGD
Ensembl		 PMID:4275392 GO_REF:0000107 NCBI chr20:30,773,222...30,874,814
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hk2 hexokinase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29298880)		 Ensembl
RGD		 PMID:29298880 GO_REF:0000107 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Pfkl phosphofructokinase, liver type involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:10,663,907...10,685,967
Ensembl chr20:10,664,272...10,686,315 		JBrowse link
G Pfkm phosphofructokinase, muscle involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
MGI:1196256 (PMID:27760309), (PMID:28049690), (PMID:4275392)
MGI:4356541 (PMID:19696889)		 Ensembl
GO_Central
RGD		 PMID:4275392 PMID:19696889 PMID:27760309 PMID:28049690 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:131,100,684...131,138,250
Ensembl chr 7:129,221,653...129,259,192 		JBrowse link
G Pfkp phosphofructokinase, platelet involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:68,639,749...68,704,055
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 involved_in ISO (PMID:12189148) RGD PMID:12189148 NCBI chr 1:250,673,152...250,680,762
Ensembl chr 1:240,723,920...240,738,452 		JBrowse link
G Pgam2 phosphoglycerate mutase 2 involved_in ISO
IEA		 (PMID:23951293)
GO_REF:0000107		 RGD
Ensembl		 PMID:23951293 GO_REF:0000107 NCBI chr14:84,895,763...84,897,874
Ensembl chr14:80,681,776...80,683,940 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 involved_in ISO
IEA		 MGI:3780541 (PMID:30174313)
GO_REF:0000107		 RGD
Ensembl		 PMID:30174313 GO_REF:0000107 NCBI chr  X:75,336,988...75,352,962
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgk1l1 phosphoglycerate kinase 1 like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:44,487,980...44,489,330
Ensembl chr 2:42,754,639...42,755,856 		JBrowse link
G Pkm pyruvate kinase M1/2 involved_in ISO (PMID:28630053) RGD PMID:28630053 NCBI chr 8:68,949,731...68,975,394
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:4275392) RGD PMID:4275392 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tpi1 triosephosphate isomerase 1 involved_in ISO MGI:3780541 (PMID:30174313) RGD PMID:30174313 NCBI chr 4:159,301,558...159,305,088
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
D-ribose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt5 nudix hydrolase 5 involved_in ISO
ISS		 (PMID:21389046)
GO_REF:0000024		 RGD
UniProt		 PMID:21389046 GO_REF:0000024 NCBI chr17:72,435,690...72,459,008
Ensembl chr17:72,435,697...72,459,001 		JBrowse link
G Rbks ribokinase involved_in IEA GO_REF:0000041
GO_REF:0000104		 UniProt GO_REF:0000041 GO_REF:0000104 NCBI chr 6:30,467,724...30,544,284
Ensembl chr 6:24,747,293...24,824,290 		JBrowse link
D-xylose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhdh dihydrodiol dehydrogenase involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:6753830)		 GO_Central
Ensembl
RGD		 PMID:6753830 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:105,088,108...105,102,560
Ensembl chr 1:95,953,092...95,965,197 		JBrowse link
fructose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:29414685), (PMID:4343087)		 Ensembl
RGD		 PMID:4343087 PMID:29414685 GO_REF:0000107 NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:227,627,977...227,667,877
Ensembl chr 1:218,201,472...218,248,906 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B involved_in ISO
IEA		 MGI:4951216 (PMID:29533924), (PMID:4343087)
GO_REF:0000107		 RGD
Ensembl		 PMID:4343087 PMID:29533924 GO_REF:0000107 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Glyctk glycerate kinase involved_in ISO (PMID:29414685) RGD PMID:29414685 NCBI chr 8:115,676,071...115,681,403
Ensembl chr 8:106,797,343...106,802,397 		JBrowse link
G Khk ketohexokinase involved_in ISO MGI:4398729 (PMID:23813872), (PMID:4343087) RGD PMID:4343087 PMID:23813872 NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:25,445,300...25,455,717 		JBrowse link
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldob aldolase, fructose-bisphosphate B involved_in IEA
ISO		 GO_REF:0000107
MGI:4951216 (PMID:29533924)		 Ensembl
RGD		 PMID:29533924 GO_REF:0000107 NCBI chr 5:68,684,541...68,697,582
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Khk ketohexokinase involved_in ISO MGI:4398729 (PMID:23813872), (PMID:24022321), (PMID:27465991) RGD PMID:23813872 PMID:24022321 PMID:27465991 NCBI chr 6:31,165,246...31,175,779
Ensembl chr 6:25,445,300...25,455,717 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISO MGI:6471029 (PMID:32818435) RGD PMID:32818435 NCBI chr 1:216,664,446...216,677,815
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
galactose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin2a beta-galactosidase-like protein involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:25,248,570...25,287,173
Ensembl chr 8:25,248,570...25,287,173 		JBrowse link
G Gale UDP-galactose-4-epimerase involved_in ISO (PMID:16302980) RGD PMID:16302980 NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Glb1 galactosidase, beta 1 involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:6811372 GO_REF:0000033, RGD:1598981 NCBI chr 8:122,963,718...123,036,326
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Glb1l galactosidase, beta 1-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:76,693,325...76,705,548
Ensembl chr 9:76,695,173...76,705,510 		JBrowse link
G Glb1l2 galactosidase, beta 1-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:25,115,462...25,166,843
Ensembl chr 8:25,115,462...25,166,783 		JBrowse link
G Glb1l3 galactosidase, beta 1-like 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:25,179,165...25,220,904
Ensembl chr 8:25,179,165...25,220,904 		JBrowse link
galactose catabolic process via UDP-galactose, Leloir pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gale UDP-galactose-4-epimerase involved_in ISO
IBA		 (PMID:28877911)
GO_REF:0000033		 RGD
GO_Central		 PMID:28877911 GO_REF:0000033 NCBI chr 5:153,477,420...153,481,926
Ensembl chr 5:148,194,791...148,198,388 		JBrowse link
G Galk1 galactokinase 1 involved_in ISO
IEA		 MGI:2148688 (PMID:10915771)
GO_REF:0000107		 RGD
Ensembl		 PMID:10915771 GO_REF:0000107 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337 		JBrowse link
G Galm galactose mutarotase involved_in ISO
IBA		 (PMID:30451973)
GO_REF:0000033		 RGD
GO_Central		 PMID:30451973 GO_REF:0000033 NCBI chr 6:20,589,775...20,641,516
Ensembl chr 6:14,837,548...14,889,310 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase involved_in ISO
IBA		 MGI:2180188 (PMID:8902187)
GO_REF:0000033		 RGD
GO_Central		 PMID:8902187 GO_REF:0000033 NCBI chr 5:61,722,871...61,726,128
Ensembl chr 5:56,926,724...56,930,265 		JBrowse link
G Pgm1 phosphoglucomutase 1 involved_in ISO
IEA		 (PMID:30982613)
GO_REF:0000107		 RGD
Ensembl		 PMID:30982613 GO_REF:0000107 NCBI chr 5:119,710,734...119,770,159
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
glucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:22998876 RGD:329412477 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:2675966|MGI:3029528 (PMID:12931191) RGD PMID:12931191 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Gck glucokinase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:12941786)		 UniProt
Ensembl
RGD		 PMID:12941786 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,999,019...85,041,098
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Hk2 hexokinase 2 IDA RGD PMID:7948023 RGD:597805901 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Lrp5 LDL receptor related protein 5 involved_in ISO
IEA		 (PMID:19673927)
GO_REF:0000107		 RGD
Ensembl		 PMID:19673927 GO_REF:0000107 NCBI chr 1:210,243,499...210,346,886
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IDA RGD PMID:16980436 RGD:2304071 NCBI chr13:44,683,499...44,727,135
Ensembl chr13:42,147,478...42,174,699 		JBrowse link
glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A acts_upstream_of_or_within ISO MGI:2384559 (PMID:8224816) RGD PMID:8224816 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of ISO
IEA		 (PMID:20935145)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935145 GO_REF:0000107 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of ISO
IEA		 (PMID:20935145)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935145 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
glycolytic process from galactose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galk1 galactokinase 1 acts_upstream_of_or_within ISO
IEA		 MGI:2148688 (PMID:10915771)
GO_REF:0000107		 RGD
Ensembl		 PMID:10915771 GO_REF:0000107 NCBI chr10:101,243,146...101,247,323
Ensembl chr10:101,235,994...101,247,337 		JBrowse link
G Galt galactose-1-phosphate uridylyltransferase acts_upstream_of_or_within ISO MGI:2180188 (PMID:11286504) RGD PMID:11286504 NCBI chr 5:61,722,871...61,726,128
Ensembl chr 5:56,926,724...56,930,265 		JBrowse link
L-fucose catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b14 hydroxysteroid (17-beta) dehydrogenase 14 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:38944119)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:38944119 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:105,165,695...105,176,045
Ensembl chr 1:96,029,284...96,039,883 		JBrowse link
mannose to fructose-6-phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpi mannose phosphate isomerase involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:8307007), (PMID:9525984)
MGI:3628756 (PMID:16339137)		 UniProt
Ensembl
RGD		 PMID:8307007 PMID:9525984 PMID:16339137 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:66,843,802...66,852,108
Ensembl chr 8:57,947,893...57,956,150 		JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:76,504,868...76,599,536
Ensembl chr 3:56,097,269...56,192,100 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO
IEA		 (PMID:20935145)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935145 GO_REF:0000107 NCBI chr 4:161,613,306...161,632,248
Ensembl chr 4:159,927,139...159,946,029
Ensembl chr 6:159,927,139...159,946,029 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO
IEA		 (PMID:20935145)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935145 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
positive regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO
IEA		 (PMID:17828264)
GO_REF:0000107		 RGD
Ensembl		 PMID:17828264 GO_REF:0000107 NCBI chr 1:211,588,473...211,604,401
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:20436681) RGD PMID:20436681 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        catabolic process 2970
          small molecule catabolic process 378
            monosaccharide catabolic process 52
              1,5-anhydro-D-fructose catabolic process 0
              2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
              D-galacturonate catabolic process 0
              L-ascorbic acid catabolic process 0
              hexose catabolic process + 49
              pentose catabolic process + 3
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      metabolic process 12206
        primary metabolic process 10763
          carbohydrate metabolic process 650
            monosaccharide metabolic process 301
              monosaccharide catabolic process 52
                1,5-anhydro-D-fructose catabolic process 0
                2-dehydro-3-deoxy-D-gluconic acid catabolic process 0
                D-galacturonate catabolic process 0
                L-ascorbic acid catabolic process 0
                hexose catabolic process + 49
                pentose catabolic process + 3
paths to the root