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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of muscle contraction
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Accession:GO:0045933 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of muscle contraction.
Synonyms:exact_synonym: up regulation of muscle contraction;   upregulation of muscle contraction
 narrow_synonym: activation of muscle contraction;   stimulation of muscle contraction



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positive regulation of muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:166,002,867...166,014,252 JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP
PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:73,578,747...73,650,184 JBrowse link
positive regulation of cardiac muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:12075344)
Ensembl
RGD
PMID:12075344 GO_REF:0000107 NCBI chr  X:33,925,458...33,972,851 JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:45,005,648...45,111,416 JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19707545 RGD:2314476 NCBI chr 1:22,621,498...22,624,614 JBrowse link
G Chga chromogranin A involved_in IDA PMID:22459152 UniProt PMID:22459152 RGD:6906968 NCBI chr 6:127,460,895...127,472,238 JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 IEP RGD PMID:21620734 RGD:5686387 NCBI chr 6:135,523,604...135,529,687 JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19646991)
Ensembl
RGD
PMID:19646991 GO_REF:0000107 NCBI chr 1:207,721,134...208,054,073 JBrowse link
G Nppa natriuretic peptide A involved_in ISO
IEA
(PMID:19646991)
GO_REF:0000107
RGD
Ensembl
PMID:19646991 GO_REF:0000107 NCBI chr 5:163,712,184...163,713,493 JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (PMID:19127022), (PMID:21291891) RGD PMID:19127022 PMID:21291891 NCBI chr13:58,350,063...58,352,666 JBrowse link
G Smtn smoothelin acts_upstream_of_or_within ISO MGI:3613292|MGI:3613293 (PMID:18678771) RGD PMID:18678771 NCBI chr14:78,398,595...78,420,908 JBrowse link
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:30,958,086...30,958,916 JBrowse link
positive regulation of colon smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:17322067 RGD:12910822 NCBI chr14:32,901,615...32,978,895 JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:24170253 RGD:10043193 NCBI chr 2:249,264,985...249,409,966 JBrowse link
positive regulation of fast-twitch skeletal muscle fiber contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07005775.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Actn3 actinin alpha 3 involved_in ISO (PMID:18178581) RGD PMID:18178581 NCBI chr 1:211,588,473...211,604,401 JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
IEA
ISS
(PMID:12479237)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12479237 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:190,457,198...190,475,410 JBrowse link
G Mylk2 myosin light chain kinase 2 IMP RGD PMID:12748068 RGD:1580242 NCBI chr 3:141,376,450...141,388,357 JBrowse link
positive regulation of gastro-intestinal system smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 RGD:12907565 NCBI chr 4:148,421,315...148,431,128 JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:150,049,322...150,079,060 JBrowse link
G Spx spexin hormone involved_in ISO
IBA
ISS
(PMID:17284679)
GO_REF:0000033
RGD
GO_Central
PMID:17284679 PMID:17284679 GO_REF:0000033, RGD:12907558 NCBI chr 4:175,356,044...175,362,082 JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:138,235,754...138,236,594 JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:45,531,480...45,611,492 JBrowse link
positive regulation of pyloric antrum smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:9832052 RGD:12910753 NCBI chr14:32,901,615...32,978,895 JBrowse link
positive regulation of small intestine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:15890336 PMID:21874246 RGD:12907565, RGD:12910732 NCBI chr 4:148,421,315...148,431,128 JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:112,196,158...112,201,666 JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:7542218 RGD:12910748 NCBI chr14:32,901,615...32,978,895 JBrowse link
positive regulation of smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:18340377)
Ensembl
RGD
PMID:18340377 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283 JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP
ISO
IEA
(PMID:21335239)
GO_REF:0000107
RGD
Ensembl
PMID:21335239 PMID:19041301 GO_REF:0000107, RGD:5688345 NCBI chr15:45,005,648...45,111,416 JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 acts_upstream_of_or_within ISO (PMID:12925702) RGD PMID:12925702 NCBI chr17:60,005,137...60,467,250 JBrowse link
G Cttn cortactin involved_in ISO
IEA
UniProtKB:P07737 (PMID:24700464)
GO_REF:0000107
RGD
Ensembl
PMID:24700464 GO_REF:0000107 NCBI chr 1:209,029,048...209,064,577 JBrowse link
G Edn1 endothelin 1 involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
IMP
GO_REF:0000033
(PMID:8010105)
GO_Central
RGD
PMID:8010105 PMID:12396026 PMID:8893723 GO_REF:0000033, RGD:1581797, RGD:8662282 NCBI chr17:22,660,799...22,666,687 JBrowse link
G Edn2 endothelin 2 involved_in
acts_upstream_of_or_within
IDA
IBA
ISO
IEA
GO_REF:0000033
(PMID:2768235)
GO_REF:0000107
GO_Central
RGD
Ensembl
PMID:2768235 PMID:12396026 GO_REF:0000033 GO_REF:0000107, RGD:1581797 NCBI chr 5:139,036,576...139,042,074 JBrowse link
G Edn3 endothelin 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:163,562,307...163,586,636 JBrowse link
G F2r coagulation factor II (thrombin) receptor IDA RGD PMID:14699501 RGD:1582292 NCBI chr 2:28,604,066...28,620,579 JBrowse link
G Itga2 integrin subunit alpha 2 IMP SMC-containing collagen lattice contraction RGD PMID:16263112 RGD:2307398 NCBI chr 2:48,253,412...48,354,509 JBrowse link
G Myocd myocardin involved_in ISO
IEA
(PMID:17215356)
GO_REF:0000107
RGD
Ensembl
PMID:17215356 GO_REF:0000107 NCBI chr10:50,332,356...50,426,819 JBrowse link
G Nmu neuromedin U involved_in IMP
IBA
IDA
GO_REF:0000033
PMID:3178840
GO_Central
RGD
PMID:16474416 PMID:3178840 GO_REF:0000033, RGD:1642122, RGD:13461757 NCBI chr14:31,844,564...31,872,196 JBrowse link
G Npnt nephronectin involved_in ISO (PMID:21335239) RGD PMID:21335239 NCBI chr 2:221,391,151...221,459,527 JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP neuropeptide Y- and peptide YY-induced contraction in ascending and descending colon RGD PMID:10422644 RGD:1642606 NCBI chr 2:170,200,027...170,210,286 JBrowse link
G Prok2 prokineticin 2 involved_in ISO (PMID:11259612) RGD PMID:11259612 NCBI chr 4:133,903,210...133,918,126 JBrowse link
G Ptafr platelet-activating factor receptor IMP RGD PMID:10821044 RGD:10043148 NCBI chr 5:150,049,322...150,079,060 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 IMP RGD PMID:18480553 RGD:2300247 NCBI chr 3:39,981,419...40,002,993 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18480553 RGD:2300247 NCBI chr13:64,714,063...64,722,320 JBrowse link
G Rhoa ras homolog family member A IMP RGD PMID:17379756 RGD:1642962 NCBI chr 8:117,870,548...117,904,303 JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO
IEA
(PMID:12847068)
GO_REF:0000107
RGD
Ensembl
PMID:12847068 GO_REF:0000107 NCBI chr10:101,758,567...101,764,240 JBrowse link
G Srf serum response factor involved_in ISO (PMID:17215356) RGD PMID:17215356 NCBI chr 9:14,426,453...14,435,734 JBrowse link
G Tbxa2r thromboxane A2 receptor acts_upstream_of_or_within ISO (PMID:12925702) RGD PMID:12925702 NCBI chr 7:9,034,077...9,041,489 JBrowse link
positive regulation of smooth muscle contraction involved in micturition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:18562635 RGD:10043314 NCBI chr 2:249,264,985...249,409,966 JBrowse link
positive regulation of stomach fundus smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:2055247 UniProt PMID:2055247 RGD:13461751 NCBI chr14:31,844,564...31,872,196 JBrowse link
positive regulation of striated muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2451290 (PMID:11507009)
Ensembl
RGD
PMID:11507009 GO_REF:0000107 NCBI chr 2:191,709,311...191,737,414 JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 IMP RGD PMID:32706268 RGD:38549369 NCBI chr12:47,599,161...47,638,143 JBrowse link
positive regulation of uterine smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:7,503,351...7,599,474 JBrowse link
G Adra2b adrenoceptor alpha 2B IMP RGD PMID:19634638 PMID:17664026 RGD:2313546, RGD:6893570 NCBI chr 3:114,585,174...114,589,220 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO
IEA
ISS
(PMID:21427217)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:21427217 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,331,073...20,336,527 JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase IMP RGD PMID:19208792 RGD:2316554 NCBI chr 5:147,172,642...147,201,267 JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19164477 RGD:2303954 NCBI chr 3:138,235,754...138,236,594 JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:19164477 RGD:2303954 NCBI chr 4:145,598,549...145,614,674 JBrowse link
G Tacr1 tachykinin receptor 1 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 4:114,920,844...115,089,733 JBrowse link
G Tacr2 tachykinin receptor 2 IDA RGD PMID:12390879 RGD:2305937 NCBI chr20:30,208,907...30,223,446 JBrowse link
G Tacr3 tachykinin receptor 3 IDA RGD PMID:12390879 RGD:2305937 NCBI chr 2:223,266,536...223,363,791 JBrowse link
positive regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm3 cholinergic receptor, muscarinic 3 IMP RGD PMID:8428203 RGD:2303387 NCBI chr17:60,005,137...60,467,250 JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:22158624) RGD PMID:22158624 NCBI chr10:71,902,600...71,902,691 JBrowse link
G Rhoa ras homolog family member A acts_upstream_of_or_within ISO (PMID:24335996) RGD PMID:24335996 NCBI chr 8:117,870,548...117,904,303 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20534
    positive regulation of biological process 6760
      positive regulation of multicellular organismal process 1892
        positive regulation of muscle contraction 54
          positive regulation of smooth muscle contraction + 37
          positive regulation of striated muscle contraction + 16
Path 2
Term Annotations click to browse term
  biological_process 20534
    biological regulation 13821
      regulation of biological process 13375
        regulation of multicellular organismal process 3340
          regulation of system process 683
            regulation of muscle system process 282
              regulation of muscle contraction 175
                positive regulation of muscle contraction 54
                  positive regulation of smooth muscle contraction + 37
                  positive regulation of striated muscle contraction + 16
paths to the root