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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipid metabolic process
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Accession:GO:0045833 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
Synonyms:exact_synonym: down regulation of lipid metabolic process;   downregulation of lipid metabolic process;   negative regulation of lipid metabolism
 narrow_synonym: inhibition of lipid metabolic process

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negative regulation of lipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004936706:1,531,219...1,531,921 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936484:2,455,819...2,567,467
Ensembl chrNW_004936484:2,455,819...2,568,682 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:6,428,824...6,477,007
Ensembl chrNW_004936528:6,429,973...6,477,218 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chrNW_004936599:923,943...932,428
Ensembl chrNW_004936599:923,943...932,321 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chrNW_004936520:7,926,273...8,504,777
Ensembl chrNW_004936520:7,926,280...8,526,149 		JBrowse link
G Prox1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936628:4,185,712...4,240,680
Ensembl chrNW_004936628:4,185,706...4,238,451 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chrNW_004936537:6,610,565...6,618,509
Ensembl chrNW_004936537:6,610,565...6,618,450 		JBrowse link
G LOC101978323 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chrNW_004936646:1,899,686...1,904,104
Ensembl chrNW_004936646:1,900,259...1,904,104 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chrNW_004936520:733,760...850,563
Ensembl chrNW_004936520:733,668...829,435 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936506:8,197,116...8,208,712
Ensembl chrNW_004936506:8,196,784...8,210,584 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936646:280,745...283,488
Ensembl chrNW_004936646:280,661...287,144 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chrNW_004936490:15,069,435...15,076,112
Ensembl chrNW_004936490:15,069,387...15,076,253 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936594:1,482,830...1,489,337
Ensembl chrNW_004936594:1,486,111...1,489,188 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Chlsn cholesin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,213,948...1,332,534
Ensembl chrNW_004936754:1,214,480...1,324,497 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:80,583...116,027
Ensembl chrNW_004936636:80,564...116,694 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936710:1,193,679...1,210,059
Ensembl chrNW_004936710:1,193,411...1,210,739 		JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chrNW_004936484:13,086,928...13,092,291
Ensembl chrNW_004936484:13,088,030...13,092,291 		JBrowse link
G Insig1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936527:9,684,304...9,696,951
Ensembl chrNW_004936527:9,685,695...9,692,830 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936601:5,015,922...5,016,942
Ensembl chrNW_004936601:5,015,219...5,160,908 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:6,428,824...6,477,007
Ensembl chrNW_004936528:6,429,973...6,477,218 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004936482:19,018,454...19,040,438 JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:950,970...1,053,671
Ensembl chrNW_004936769:950,845...1,051,887 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936621:620,163...639,115
Ensembl chrNW_004936621:620,074...639,093 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chrNW_004936510:3,779,930...3,806,615
Ensembl chrNW_004936510:3,781,210...3,802,693 		JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chrNW_004936469:50,981,198...50,986,224
Ensembl chrNW_004936469:50,980,595...50,986,506 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23209793) Ensembl
ARUK-UCL		 PMID:23209793 GO_REF:0000107 NCBI chrNW_004936474:21,790,807...21,803,336
Ensembl chrNW_004936474:21,790,747...21,803,360 		JBrowse link
G Pink1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chrNW_004936474:6,574,471...6,589,478
Ensembl chrNW_004936474:6,573,623...6,589,478 		JBrowse link
G Plin5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,629,762...2,637,303
Ensembl chrNW_004936588:2,629,762...2,636,983 		JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936607:4,533,607...4,541,230
Ensembl chrNW_004936607:4,532,230...4,541,283 		JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004936845:66,674...96,248
Ensembl chrNW_004936845:66,241...96,249 		JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:514,883...520,223
Ensembl chrNW_004936595:514,534...520,223 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:16326698) UniProt PMID:16326698 NCBI chrNW_004936490:17,735,444...17,801,456 JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936495:12,289,648...12,357,640
Ensembl chrNW_004936495:12,288,748...12,356,919 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936636:80,583...116,027
Ensembl chrNW_004936636:80,564...116,694 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936710:1,193,679...1,210,059
Ensembl chrNW_004936710:1,193,411...1,210,739 		JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chrNW_004936527:9,684,304...9,696,951
Ensembl chrNW_004936527:9,685,695...9,692,830 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chrNW_004936469:52,120,063...52,140,646
Ensembl chrNW_004936469:52,117,733...52,140,765 		JBrowse link
G Klhl25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936483:12,001,111...12,033,158
Ensembl chrNW_004936483:12,000,514...12,009,705 		JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101970910 cytochrome P450 7A1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chrNW_004936496:4,599,138...4,605,653
Ensembl chrNW_004936496:4,599,138...4,605,653 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:18,077,850...18,082,817
Ensembl chrNW_004936485:18,077,850...18,083,553 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:5,373,303...5,492,950
Ensembl chrNW_004936474:5,373,186...5,493,635 		JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17767906) Ensembl
TreeGrafter
MGI		 PMID:17767906 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:11,565,535...11,631,660
Ensembl chrNW_004936474:11,565,479...11,634,214 		JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357 		JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936821:382,756...538,254
Ensembl chrNW_004936821:382,383...536,223 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936473:27,532,480...27,541,257
Ensembl chrNW_004936473:27,532,480...27,535,659 		JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:950,970...1,053,671
Ensembl chrNW_004936769:950,845...1,051,887 		JBrowse link
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004936845:66,674...96,248
Ensembl chrNW_004936845:66,241...96,249 		JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936595:514,883...520,223
Ensembl chrNW_004936595:514,534...520,223 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:9,477,483...9,526,692
Ensembl chrNW_004936492:9,477,373...9,526,692 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004936498:4,514,212...4,544,523
Ensembl chrNW_004936498:4,514,184...4,544,527 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chrNW_004936481:15,885,375...15,910,216
Ensembl chrNW_004936481:15,885,280...15,910,267 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004936481:15,737,491...15,767,344 JBrowse link
G LOC101969732 dimethylaniline monooxygenase [N-oxide-forming] 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:15,857,556...15,873,883
Ensembl chrNW_004936481:15,857,559...15,880,184 		JBrowse link
G Sirt4 sirtuin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936668:628,875...633,425
Ensembl chrNW_004936668:626,938...633,466 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936655:1,849,044...1,852,648
Ensembl chrNW_004936655:1,847,272...1,852,705 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17234593) Ensembl
MGI		 PMID:17234593 GO_REF:0000107 NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638 		JBrowse link
negative regulation of lipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Asxl3 ASXL transcriptional regulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936517:11,064,986...11,074,992
Ensembl chrNW_004936517:11,064,987...11,165,956 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28827783) Ensembl
MGI		 PMID:28827783 GO_REF:0000107 NCBI chrNW_004936484:2,455,819...2,567,467
Ensembl chrNW_004936484:2,455,819...2,568,682 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:1,288,891...1,293,555
Ensembl chrNW_004936754:1,288,912...1,293,427 		JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (PMID:18544705) UniProt PMID:18544705 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chrNW_004936846:83,727...92,392
Ensembl chrNW_004936846:83,727...92,398 		JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004936612:2,691,729...2,810,975
Ensembl chrNW_004936612:2,691,524...2,810,981 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936769:950,970...1,053,671
Ensembl chrNW_004936769:950,845...1,051,887 		JBrowse link
G Adora1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chrNW_004936567:1,430,128...1,508,626
Ensembl chrNW_004936567:1,429,817...1,462,532 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:1,837,785...1,841,019
Ensembl chrNW_004936486:1,838,176...1,839,630 		JBrowse link
G Alk ALK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936493:3,624,288...3,671,567
Ensembl chrNW_004936493:3,028,608...3,671,874 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936903:520,420...521,726
Ensembl chrNW_004936903:520,650...521,910 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chrNW_004936581:567,426...576,859
Ensembl chrNW_004936581:567,662...578,267 		JBrowse link
G Cidea cell death inducing DFFA like effector a involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936626:230,372...246,893
Ensembl chrNW_004936626:230,329...246,893 		JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936602:3,312,146...3,323,009
Ensembl chrNW_004936602:3,313,208...3,322,604 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21164481) Ensembl
MGI		 PMID:21164481 GO_REF:0000107 NCBI chrNW_004936483:16,356,663...16,465,128
Ensembl chrNW_004936483:16,356,689...16,455,073 		JBrowse link
G Hcar1 hydroxycarboxylic acid receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936558:1,890,027...1,893,632
Ensembl chrNW_004936558:1,890,439...1,891,480 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357 		JBrowse link
G LOC101973720 rap guanine nucleotide exchange factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936512:5,636,197...5,659,606
Ensembl chrNW_004936512:5,636,758...5,659,300
Ensembl chrNW_004936512:5,636,758...5,659,300 		JBrowse link
G LOC101978400 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chrNW_004936558:1,899,313...1,901,409 JBrowse link
G Pde3b phosphodiesterase 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936528:3,922,436...4,087,991
Ensembl chrNW_004936528:3,923,379...4,087,188 		JBrowse link
G Plin1 perilipin 1 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chrNW_004936483:15,457,299...15,470,674
Ensembl chrNW_004936483:15,457,297...15,470,350 		JBrowse link
G Plin5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,629,762...2,637,303
Ensembl chrNW_004936588:2,629,762...2,636,983 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936518:1,817,051...1,843,376
Ensembl chrNW_004936518:1,804,969...1,843,380 		JBrowse link
G Tnf tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936727:1,936,066...1,937,766
Ensembl chrNW_004936727:1,936,066...1,937,766 		JBrowse link
negative regulation of lipoprotein lipid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936833:260,798...277,060
Ensembl chrNW_004936833:259,660...277,246 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004936532:7,596,279...7,654,139
Ensembl chrNW_004936532:7,605,965...7,652,573 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20018880) Ensembl
MGI		 PMID:20018880 GO_REF:0000107 NCBI chrNW_004936815:281,664...345,915
Ensembl chrNW_004936815:292,200...344,413 		JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936754:808,894...828,554
Ensembl chrNW_004936754:808,213...828,613 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:2,353,840...2,368,573
Ensembl chrNW_004936492:2,353,841...2,368,573 		JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:922,978...941,996
Ensembl chrNW_004936669:926,622...942,167 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004936552:7,204,298...7,212,632 JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936511:7,860,552...8,082,850
Ensembl chrNW_004936511:7,860,590...8,081,525 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936654:1,336,546...1,464,959
Ensembl chrNW_004936654:1,336,429...1,461,476 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:922,978...941,996
Ensembl chrNW_004936669:926,622...942,167 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004936602:1,938,720...2,179,239
Ensembl chrNW_004936602:1,935,507...2,179,256 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:12,428,765...12,439,570
Ensembl chrNW_004936485:12,428,710...12,439,454 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:5,350,870...5,464,561
Ensembl chrNW_004936476:5,350,870...5,464,354 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chrNW_004936602:2,182,053...2,185,297
Ensembl chrNW_004936602:2,183,831...2,185,297 		JBrowse link
G Insig1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chrNW_004936527:9,684,304...9,696,951
Ensembl chrNW_004936527:9,685,695...9,692,830 		JBrowse link
G Insig2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chrNW_004936469:52,120,063...52,140,646
Ensembl chrNW_004936469:52,117,733...52,140,765 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:9384387) HGNC-UCL
Ensembl		 PMID:9384387 GO_REF:0000107 NCBI chrNW_004936553:6,436,371...6,440,141
Ensembl chrNW_004936553:6,436,371...6,440,141 		JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21187369) Ensembl
MGI		 PMID:21187369 GO_REF:0000107 NCBI chrNW_004936549:5,212,693...5,450,195
Ensembl chrNW_004936549:5,212,834...5,448,515 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004936669:922,978...941,996
Ensembl chrNW_004936669:926,622...942,167 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936664:3,257,744...3,263,787
Ensembl chrNW_004936664:3,257,698...3,264,565 		JBrowse link
G Wnt4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936474:7,623,462...7,635,416
Ensembl chrNW_004936474:7,623,463...7,635,664 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chrNW_004936492:13,315,265...13,365,186
Ensembl chrNW_004936492:13,315,265...13,374,034 		JBrowse link
G Sik1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:774,749...784,326
Ensembl chrNW_004936500:774,092...784,330 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
G Tmx1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936495:14,432,971...14,447,380
Ensembl chrNW_004936495:14,431,137...14,447,476 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936542:2,106,927...2,108,412
Ensembl chrNW_004936542:2,106,318...2,108,603 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chrNW_004936671:780,173...827,628
Ensembl chrNW_004936671:782,135...827,771 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chrNW_004936479:17,084,006...17,112,264
Ensembl chrNW_004936479:17,084,920...17,112,258 		JBrowse link
G Plin5 perilipin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936588:2,629,762...2,637,303
Ensembl chrNW_004936588:2,629,762...2,636,983 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936542:6,192,407...6,352,835
Ensembl chrNW_004936542:6,192,407...6,352,424 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9240444) Ensembl
MGI		 PMID:9240444 GO_REF:0000107 NCBI chrNW_004939393:628...6,234
Ensembl chrNW_004939393:628...6,201 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Ccnc cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004936651:1,123,546...1,159,089
Ensembl chrNW_004936651:1,140,895...1,163,944 		JBrowse link
G Cdk8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004936948:91,578...236,051 JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in ISO (PMID:18682832) UniProt PMID:18682832 NCBI chrNW_004936602:3,312,146...3,323,009
Ensembl chrNW_004936602:3,313,208...3,322,604 		JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chrNW_004936489:4,616,839...4,887,179
Ensembl chrNW_004936489:4,614,754...4,887,171 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:28483554) Ensembl
BHF-UCL		 PMID:28483554 GO_REF:0000107 NCBI chrNW_004936741:1,408,669...1,419,717
Ensembl chrNW_004936741:1,406,521...1,419,776 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936514:4,456,498...4,462,436
Ensembl chrNW_004936514:4,456,484...4,462,987 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936590:3,813,916...3,817,642
Ensembl chrNW_004936590:3,813,888...3,817,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17413
    cellular process 17016
      negative regulation of cellular process 5143
        negative regulation of metabolic process 2847
          negative regulation of lipid metabolic process 104
            negative regulation of fatty acid metabolic process + 36
            negative regulation of isoprenoid metabolic process + 1
            negative regulation of lipid biosynthetic process + 59
            negative regulation of lipid catabolic process + 30
            negative regulation of lipoprotein lipid oxidation 1
            negative regulation of phospholipid metabolic process + 6
            negative regulation of steroid metabolic process + 28
            negative regulation of triglyceride metabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 17413
    biological regulation 11405
      regulation of biological process 11039
        regulation of cellular process 10717
          regulation of metabolic process 5915
            regulation of primary metabolic process 4847
              regulation of lipid metabolic process 353
                negative regulation of lipid metabolic process 104
                  negative regulation of fatty acid metabolic process + 36
                  negative regulation of isoprenoid metabolic process + 1
                  negative regulation of lipid biosynthetic process + 59
                  negative regulation of lipid catabolic process + 30
                  negative regulation of lipoprotein lipid oxidation 1
                  negative regulation of phospholipid metabolic process + 6
                  negative regulation of steroid metabolic process + 28
                  negative regulation of triglyceride metabolic process + 16
paths to the root