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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipid metabolic process
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Accession:GO:0045833 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
Synonyms:exact_synonym: down regulation of lipid metabolic process;   downregulation of lipid metabolic process;   negative regulation of lipid metabolism
 narrow_synonym: inhibition of lipid metabolic process


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negative regulation of lipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC2 apolipoprotein C2 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chr 6:51,404,219...51,406,302 JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G LOC100510975 coiled-coil domain-containing protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:59,052,979...59,144,791
Ensembl chr10:59,052,915...59,144,797 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,192...47,444,660 		JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in ISO (PMID:16959810) UniProt PMID:16959810 NCBI chr 6:80,110,238...80,138,165 JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23747249) MGI
Ensembl		 PMID:23747249 GO_REF:0000107 NCBI chr 2:3,583,027...3,586,985
Ensembl chr 2:3,582,828...3,587,752 		JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chr10:54,782,806...55,381,043
Ensembl chr10:54,783,056...55,536,068 		JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:129,527,704...129,583,693
Ensembl chr 9:129,532,184...129,580,982 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,053,892...23,058,470 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr15:94,359,784...94,377,331
Ensembl chr15:94,359,358...94,377,303 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr 5:21,262,134...21,264,689
Ensembl chr 5:21,262,193...21,264,685 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr12:22,411,130...22,417,744
Ensembl chr12:22,411,587...22,417,736 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,114,946...5,122,580
Ensembl chr12:5,114,947...5,120,083 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G C3H7orf50 chromosome 3 C7orf50 homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:650,701...745,370
Ensembl chr 3:650,704...662,486 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,643,722...48,662,648
Ensembl chr15:48,643,724...48,662,536 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G LOC110258909 isopentenyl-diphosphate Delta-isomerase 1-like acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134
G MIR185 microRNA mir-185 acts_upstream_of ISO (PMID:24296663)
(PMID:23951060)		 BHF-UCL PMID:23951060 PMID:24296663 NCBI chr14:51,449,903...51,449,978
Ensembl chr14:51,449,903...51,449,978 		JBrowse link
G MIR342 microRNA mir-342 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr 7:121,021,761...121,021,840
Ensembl chr 7:121,021,761...121,021,840 		JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:30195495) BHF-UCL PMID:30195495 NCBI chr  X:46,302,381...46,302,460
Ensembl chr  X:46,302,381...46,302,460 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:101,122,318...101,128,622
Ensembl chr14:101,123,398...101,125,593 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:47,385,244...47,444,664
Ensembl chr 2:47,385,192...47,444,660 		JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in IMP (PMID:24530842) AgBase PMID:24530842 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,467,835...56,492,602 		JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chr15:24,895,575...24,900,710
Ensembl chr15:24,895,522...24,906,372 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23209793) Ensembl
ARUK-UCL		 PMID:23209793 GO_REF:0000107 NCBI chr 6:95,738,961...95,753,245
Ensembl chr 6:95,738,969...95,753,245 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chr 6:78,863,195...78,884,663
Ensembl chr 6:78,863,190...78,884,640 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:21885430), (PMID:22675471)
(PMID:22532565)		 UniProt PMID:21885430 PMID:22532565 PMID:22675471 NCBI chr 2:74,304,613...74,314,314
Ensembl chr 2:74,300,619...74,314,315 		JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:42,568,131...42,575,983 JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr15:112,935,631...112,969,381
Ensembl chr15:112,933,506...112,969,577 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,573,521...52,581,755
Ensembl chr12:52,576,402...52,581,748 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:19,788,087...19,854,515
Ensembl chr12:19,786,020...19,854,668 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 6:49,437,308...49,460,614 JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 4:74,343,101...74,372,628
Ensembl chr 4:74,343,123...74,372,621 		JBrowse link
G DCAF5 DDB1 and CUL4 associated factor 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:92,717,544...92,813,297
Ensembl chr 7:92,715,384...92,812,979 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,643,722...48,662,648
Ensembl chr15:48,643,724...48,662,536 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr15:23,676,684...23,699,591
Ensembl chr15:23,676,683...23,699,582 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,249,009...88,291,958
Ensembl chr 7:88,262,385...88,264,691 		JBrowse link
G MIR185 microRNA mir-185 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr14:51,449,903...51,449,978
Ensembl chr14:51,449,903...51,449,978 		JBrowse link
G MIR30C-1 microRNA mir-30c-1 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 6:170,426,781...170,426,860
Ensembl chr 6:170,426,781...170,426,860 		JBrowse link
G MIR30C-2 microRNA mir-30c-2 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 1:51,383,782...51,383,861
Ensembl chr 1:51,383,782...51,383,861 		JBrowse link
G MIR342 microRNA mir-342 acts_upstream_of ISO (PMID:23951060) BHF-UCL PMID:23951060 NCBI chr 7:121,021,761...121,021,840
Ensembl chr 7:121,021,761...121,021,840 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,808,273...34,819,592
Ensembl chr17:34,807,582...34,816,451 		JBrowse link
G UBR4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,568,409...77,707,991
Ensembl chr 6:77,568,415...77,708,109 		JBrowse link
G WDTC1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:17767906) Ensembl
GO_Central
MGI		 PMID:17767906 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:84,467,532...84,537,069
Ensembl chr 6:84,467,735...84,536,584 		JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:59,256,868...59,392,564
Ensembl chr12:59,273,100...59,392,562 		JBrowse link
G SLC22A13 solute carrier family 22 member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,120,013...23,129,183
Ensembl chr13:23,120,222...23,130,829 		JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr15:112,935,631...112,969,381
Ensembl chr15:112,933,506...112,969,577 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,573,521...52,581,755
Ensembl chr12:52,576,402...52,581,748 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:19661063) UniProt PMID:19661063 NCBI chr 5:79,356,046...79,412,235
Ensembl chr 5:79,356,067...79,412,235 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr 9:10,032,163...10,066,082
Ensembl chr 9:10,032,128...10,068,437 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076 		JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chr 9:63,812,016...63,857,608
Ensembl chr 9:63,812,492...63,852,085 		JBrowse link
G FMO4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chr 9:63,908,846...63,934,985
Ensembl chr 9:63,908,868...63,934,982 		JBrowse link
G MIR199A-1 microRNA mir-199a-1 acts_upstream_of_or_within ISO (PMID:24011070) MGI PMID:24011070 NCBI chr 9:114,533,783...114,533,858
Ensembl chr 9:114,533,777...114,533,880 		JBrowse link
G MIR214 microRNA mir-214 acts_upstream_of_or_within ISO (PMID:24011070) MGI PMID:24011070 NCBI chr 9:114,527,992...114,528,101
Ensembl chr 9:114,527,990...114,528,101 		JBrowse link
G SIRT4 sirtuin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:40,290,288...40,303,887
Ensembl chr14:40,290,288...40,303,879 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17234593) Ensembl
MGI		 PMID:17234593 GO_REF:0000107 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680 		JBrowse link
negative regulation of lipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G ASXL3 ASXL transcriptional regulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:117,334,177...117,518,589
Ensembl chr 6:117,334,259...117,518,026 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18544705) UniProt PMID:18544705 NCBI chr 6:49,437,308...49,460,614 JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980 		JBrowse link
G LOC100510975 coiled-coil domain-containing protein 3 acts_upstream_of_or_within ISO (PMID:28827783) MGI PMID:28827783 NCBI chr10:59,052,979...59,144,791
Ensembl chr10:59,052,915...59,144,797 		JBrowse link
G LOC106504546 serpin A12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr 7:115,720,892...115,734,810
Ensembl chr 7:115,721,098...115,734,978 		JBrowse link
G MIR1 microRNA mir-1 involved_in ISO (PMID:23499676) BHF-UCL PMID:23499676 NCBI chr17:61,894,036...61,894,143
Ensembl chr17:61,894,036...61,894,143 		JBrowse link
G MIR206 microRNA mir-206 involved_in ISO (PMID:23499676) BHF-UCL PMID:23499676 NCBI chr 7:45,976,293...45,976,372
Ensembl chr 7:45,976,293...45,976,372 		JBrowse link
G MIR9-1 microRNA mir-9-1 acts_upstream_of ISO (PMID:25592151) ARUK-UCL PMID:25592151 NCBI chr 4:93,660,422...93,660,510 JBrowse link
G MIR9-2 microRNA mir-9-2 acts_upstream_of ISO (PMID:25592151) ARUK-UCL PMID:25592151 NCBI chr 2:96,076,352...96,076,438 JBrowse link
G MIR9-3 microRNA mir-9-3 acts_upstream_of ISO (PMID:25592151) ARUK-UCL PMID:25592151 NCBI chr 7:54,948,452...54,948,532
Ensembl chr 7:54,948,447...54,948,536 		JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr 9:39,368,555...39,483,519
Ensembl chr 9:39,368,599...39,483,515 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:41,621,574...41,739,916
Ensembl chr14:41,621,574...41,739,916 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chr 9:113,835,279...113,875,899
Ensembl chr 9:113,835,921...113,872,365 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924 		JBrowse link
G ALK ALK receptor tyrosine kinase involved_in ISO (PMID:32442405) UniProt PMID:32442405 NCBI chr 3:109,411,146...110,105,755 JBrowse link
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,319 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chr 2:9,052,676...9,064,890
Ensembl chr 2:9,052,070...9,064,886 		JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:97,253,074...97,268,355
Ensembl chr 6:97,253,074...97,267,405 		JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:66,141,836...66,149,801
Ensembl chr13:66,141,839...66,149,703 		JBrowse link
G CRTC3 CREB regulated transcription coactivator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21164481) Ensembl
MGI		 PMID:21164481 GO_REF:0000107 NCBI chr 7:53,146,317...53,255,985
Ensembl chr 7:53,146,404...53,255,977 		JBrowse link
G ENDOU endonuclease, poly(U) specific involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:78,072,062...78,090,301
Ensembl chr 5:78,072,063...78,089,680 		JBrowse link
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25912136) Ensembl
MGI		 PMID:25912136 GO_REF:0000107 NCBI chr18:10,346,029...10,350,372
Ensembl chr18:10,346,032...10,350,339 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:18465680 RGD:2293508 NCBI chr18:6,363,443...6,371,725 JBrowse link
G HCAR1 hydroxycarboxylic acid receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:30,105,285...30,106,307
Ensembl chr14:30,105,285...30,106,307 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chr14:30,117,014...30,119,293 JBrowse link
G INS insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:19032770) BHF-UCL PMID:19032770
G PDE3B phosphodiesterase 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:44,416,934...44,614,075
Ensembl chr 2:44,412,833...44,726,216 		JBrowse link
G PLIN1 perilipin 1 involved_in IMP (PMID:21701568) AgBase PMID:21701568 NCBI chr 7:55,237,517...55,250,797
Ensembl chr 7:55,236,348...55,250,797 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:21885430) UniProt PMID:21885430 NCBI chr 2:74,304,613...74,314,314
Ensembl chr 2:74,300,619...74,314,315 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
negative regulation of lipoprotein lipid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOD apolipoprotein D involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:132,514,546...132,562,594
Ensembl chr13:132,514,949...132,562,599 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPIN1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chr 3:124,940,557...125,074,137
Ensembl chr 3:124,940,561...125,074,122 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPCAT1 lysophosphatidylcholine acyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20018880) Ensembl
MGI		 PMID:20018880 GO_REF:0000107 NCBI chr16:79,134,396...79,173,775
Ensembl chr16:79,134,465...79,173,772 		JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFA platelet derived growth factor subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:296,399...322,967
Ensembl chr 3:301,584...321,712 		JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 5:8,986,462...9,007,435 JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107
G MIR30C-1 microRNA mir-30c-1 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 6:170,426,781...170,426,860
Ensembl chr 6:170,426,781...170,426,860 		JBrowse link
G MIR30C-2 microRNA mir-30c-2 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 1:51,383,782...51,383,861
Ensembl chr 1:51,383,782...51,383,861 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in IMP (PMID:24530842) AgBase PMID:24530842 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR204 microRNA mir-204 involved_in ISO (PMID:29441883) ARUK-UCL PMID:29441883 NCBI chr 1:224,065,494...224,065,602
Ensembl chr 1:224,065,494...224,065,602 		JBrowse link
G PIBF1 progesterone immunomodulatory binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,076,046...45,362,708
Ensembl chr11:45,076,062...45,362,887 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C1 aldo-keto reductase family 1, member C1 involved_in ISO (PMID:21851338) UniProt PMID:21851338 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G PRMT3 protein arginine methyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:38,884,311...39,032,944
Ensembl chr 2:38,884,362...39,032,996 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,654 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,344,924...25,468,430
Ensembl chr 7:25,344,822...25,470,470 		JBrowse link
G HRH1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chr13:67,209,261...67,411,174
Ensembl chr13:67,209,127...67,411,170 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr18:2,885,494...2,898,758
Ensembl chr18:2,885,612...2,898,767 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr15:23,676,684...23,699,591
Ensembl chr15:23,676,683...23,699,582 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 involved_in
acts_upstream_of		 IEA
ISS		 Ensembl
HGNC-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:26,117,874...26,122,951
Ensembl chr  X:26,117,874...26,122,951 		JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:15317892), (PMID:18182450) UniProt PMID:15317892 PMID:18182450 NCBI chr 6:80,110,238...80,138,165 JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE8B phosphodiesterase 8B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21187369) Ensembl
MGI		 PMID:21187369 GO_REF:0000107 NCBI chr 2:86,007,190...86,323,796
Ensembl chr 2:85,949,174...86,323,795 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,462,367...54,468,363
Ensembl chr 6:54,463,759...54,468,361 		JBrowse link
G WNT4 Wnt family member 4 involved_in ISO (PMID:12949260) UniProt PMID:12949260 NCBI chr 6:80,110,238...80,138,165 JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR30C-1 microRNA mir-30c-1 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 6:170,426,781...170,426,860
Ensembl chr 6:170,426,781...170,426,860 		JBrowse link
G MIR30C-2 microRNA mir-30c-2 acts_upstream_of ISO (PMID:23749231) BHF-UCL PMID:23749231 NCBI chr 1:51,383,782...51,383,861
Ensembl chr 1:51,383,782...51,383,861 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G SIK1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:206,454,695...206,465,802
Ensembl chr13:206,454,718...206,465,807 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:180,933,678...180,950,826
Ensembl chr 1:180,933,859...180,951,341 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC3 apolipoprotein C3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538
Ensembl chr 9:44,211,194...44,213,533 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chr 7:19,289,385...19,355,606
Ensembl chr 7:19,291,174...19,346,619 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr 9:106,698,200...106,748,217
Ensembl chr 9:106,698,207...106,745,099 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chr 2:74,304,613...74,314,314
Ensembl chr 2:74,300,619...74,314,315 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,435,350...48,653,670
Ensembl chr 9:48,435,345...48,653,655 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9240444) Ensembl
MGI		 PMID:9240444 GO_REF:0000107 NCBI chr 5:62,811,819...62,820,532
Ensembl chr 5:62,810,879...62,820,173 		JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9240444) Ensembl
MGI		 PMID:9240444 GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G CCNC cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chr 1:66,472,622...66,499,754
Ensembl chr 1:66,471,782...66,499,188 		JBrowse link
G CDK8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chr11:4,054,442...4,161,501
Ensembl chr11:4,054,442...4,161,481 		JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in ISO (PMID:18682832) UniProt PMID:18682832 NCBI chr13:66,141,836...66,149,801
Ensembl chr13:66,141,839...66,149,703 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chr 1:14,217,032...14,604,906
Ensembl chr 1:14,217,036...14,493,363 		JBrowse link
G MIR192 microRNA mir-192 acts_upstream_of ISO (PMID:28483554) BHF-UCL PMID:28483554 NCBI chr 2:7,285,667...7,285,746
Ensembl chr 2:7,285,667...7,285,746 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:28483554) BHF-UCL
Ensembl		 PMID:28483554 GO_REF:0000107 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17876
    cellular process 17418
      negative regulation of cellular process 5402
        negative regulation of metabolic process 3069
          negative regulation of lipid metabolic process 120
            negative regulation of fatty acid metabolic process + 41
            negative regulation of isoprenoid metabolic process + 2
            negative regulation of lipid biosynthetic process + 70
            negative regulation of lipid catabolic process + 31
            negative regulation of lipoprotein lipid oxidation 1
            negative regulation of phospholipid metabolic process + 7
            negative regulation of steroid metabolic process + 31
            negative regulation of triglyceride metabolic process + 19
Path 2
Term Annotations click to browse term
  biological_process 17876
    biological regulation 12990
      regulation of biological process 12608
        regulation of cellular process 12270
          regulation of metabolic process 6367
            regulation of primary metabolic process 5241
              regulation of lipid metabolic process 381
                negative regulation of lipid metabolic process 120
                  negative regulation of fatty acid metabolic process + 41
                  negative regulation of isoprenoid metabolic process + 2
                  negative regulation of lipid biosynthetic process + 70
                  negative regulation of lipid catabolic process + 31
                  negative regulation of lipoprotein lipid oxidation 1
                  negative regulation of phospholipid metabolic process + 7
                  negative regulation of steroid metabolic process + 31
                  negative regulation of triglyceride metabolic process + 19
paths to the root