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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipid metabolic process
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Accession:GO:0045833 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
Synonyms:exact_synonym: down regulation of lipid metabolic process;   downregulation of lipid metabolic process;   negative regulation of lipid metabolism
 narrow_synonym: inhibition of lipid metabolic process

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negative regulation of lipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004624907:1,758,671...1,760,611
Ensembl chrNW_004624907:1,758,696...1,760,611 		JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004624907:1,765,467...1,769,786
Ensembl chrNW_004624907:1,765,481...1,769,781 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in ISO (PMID:28827783) GO_Central PMID:28827783 NCBI chrNW_004624805:5,465,699...5,574,837
Ensembl chrNW_004624805:5,465,001...5,574,291 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624766:4,042,307...4,085,613
Ensembl chrNW_004624766:4,041,816...4,085,209 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO PMID:19342457
(PMID:19342457)		 UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004624761:12,464,243...12,495,294 JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16959810) UniProt PMID:16959810 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 ISO (PMID:12815072)
(PMID:23747249)		 UniProt
MGI		 PMID:12815072 PMID:23747249 NCBI chrNW_004624767:17,434,501...17,439,351
Ensembl chrNW_004624767:17,432,358...17,438,173 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chrNW_004624796:8,383,901...9,074,860
Ensembl chrNW_004624796:8,384,081...9,074,878 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) BHF-UCL PMID:16488887 NCBI chrNW_004624771:19,188,543...19,238,621
Ensembl chrNW_004624771:19,196,366...19,233,338 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chrNW_004624742:5,260,651...5,271,908
Ensembl chrNW_004624742:5,261,537...5,270,695 		JBrowse link
G LOC101700851 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chrNW_004624802:10,176,865...10,181,725
Ensembl chrNW_004624802:10,176,919...10,181,657 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chrNW_004624830:5,334,273...5,430,887
Ensembl chrNW_004624830:5,333,616...5,408,723 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624802:12,197,114...12,200,044
Ensembl chrNW_004624802:12,197,114...12,199,983 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004624795:3,210,382...3,216,130
Ensembl chrNW_004624795:3,209,605...3,217,539 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:16118219) UniProt PMID:16118219 NCBI chrNW_004624801:6,253,219...6,257,128 JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) RGD
BHF-UCL		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Chlsn cholesin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:26,552,102...26,671,059
Ensembl chrNW_004624740:26,549,264...26,662,409 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624737:11,977,397...12,018,437
Ensembl chrNW_004624737:11,977,397...12,018,438 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624780:5,844,473...5,861,493
Ensembl chrNW_004624780:5,843,141...5,862,039 		JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chrNW_004624800:2,533,010...2,543,754
Ensembl chrNW_004624800:2,534,967...2,543,075 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624737:39,649...41,241 JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004624766:4,042,307...4,085,613
Ensembl chrNW_004624766:4,041,816...4,085,209 		JBrowse link
G Rest RE1 silencing transcription factor involved_in ISO (PMID:19342457) UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004624761:12,464,243...12,495,294 JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004624756:4,585,542...4,593,285 JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:12,287,817...12,426,340
Ensembl chrNW_004624747:12,307,541...12,424,897 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004624734:507,880...525,295
Ensembl chrNW_004624734:509,368...525,295 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chrNW_004624799:6,100,709...6,126,530
Ensembl chrNW_004624799:6,101,728...6,126,520 		JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chrNW_004624732:25,764,260...25,769,453
Ensembl chrNW_004624732:25,764,260...25,769,419 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (PMID:23209793) ARUK-UCL PMID:23209793 NCBI chrNW_004624764:22,422,520...22,435,332
Ensembl chrNW_004624764:22,422,423...22,435,416 		JBrowse link
G Pink1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chrNW_004624764:5,656,207...5,671,260
Ensembl chrNW_004624764:5,656,229...5,671,260 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:22532565)
(PMID:21885430), (PMID:22675471)		 UniProt PMID:21885430 PMID:22532565 PMID:22675471 NCBI chrNW_004624828:5,208,060...5,218,553
Ensembl chrNW_004624828:5,207,937...5,218,901 		JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO (PMID:25416781)
(PMID:25023281)		 UniProt PMID:25023281 PMID:25416781 NCBI chrNW_004624933:958,332...970,785 JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624765:6,018,534...6,050,736 JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624786:9,838,102...9,843,506
Ensembl chrNW_004624786:9,838,227...9,843,332 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004624907:1,758,671...1,760,611
Ensembl chrNW_004624907:1,758,696...1,760,611 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:16326698) UniProt PMID:16326698 NCBI chrNW_004624795:1,186,043...1,238,986
Ensembl chrNW_004624795:1,188,136...1,241,964 		JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624734:31,911,080...32,031,634 JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624737:11,977,397...12,018,437
Ensembl chrNW_004624737:11,977,397...12,018,438 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004624780:5,844,473...5,861,493
Ensembl chrNW_004624780:5,843,141...5,862,039 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624800:2,533,010...2,543,754
Ensembl chrNW_004624800:2,534,967...2,543,075 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624732:27,089,776...27,110,170
Ensembl chrNW_004624732:27,087,674...27,104,181 		JBrowse link
G Klhl25 kelch like family member 25 involved_in ISO (PMID:27664236) UniProt PMID:27664236 NCBI chrNW_004624768:13,112,589...13,134,855
Ensembl chrNW_004624768:13,110,912...13,121,206 		JBrowse link
G LOC101701685 cholesterol 7-alpha-monooxygenase involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chrNW_004624744:33,563,564...33,619,851
Ensembl chrNW_004624744:33,612,901...33,619,869 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (PMID:16794074) BHF-UCL PMID:16794074 NCBI chrNW_004624741:1,486,223...1,494,005
Ensembl chrNW_004624741:1,484,863...1,494,829 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO (PMID:23932781) UniProt PMID:23932781 NCBI chrNW_004624764:4,223,784...4,358,923
Ensembl chrNW_004624764:4,223,784...4,358,885 		JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17767906) Ensembl
TreeGrafter
MGI		 PMID:17767906 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624764:11,151,890...11,214,716
Ensembl chrNW_004624764:11,167,206...11,214,844 		JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:14,999,088...15,000,035
Ensembl chrNW_004624767:14,999,088...15,000,035 		JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004624877:4,203,125...4,379,891
Ensembl chrNW_004624877:4,233,282...4,377,211 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:24769897) UniProt PMID:24769897 NCBI chrNW_004624773:19,950,353...19,968,029
Ensembl chrNW_004624773:19,950,303...19,962,575 		JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:12,287,817...12,426,340
Ensembl chrNW_004624747:12,307,541...12,424,897 		JBrowse link
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624765:6,018,534...6,050,736 JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004624786:9,838,102...9,843,506
Ensembl chrNW_004624786:9,838,227...9,843,332 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:19661063) UniProt PMID:19661063 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004624817:1,386,876...1,418,129
Ensembl chrNW_004624817:1,386,764...1,418,300 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004624771:10,358,422...10,386,015
Ensembl chrNW_004624771:10,357,210...10,386,005 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chrNW_004624771:10,391,267...10,422,314
Ensembl chrNW_004624771:10,390,472...10,422,524 		JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(PMID:23746352)		 UniProt PMID:23746352 PMID:24043310 NCBI chrNW_004624747:13,329,662...13,352,151
Ensembl chrNW_004624747:13,335,442...13,352,201 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:32103177) UniProt PMID:32103177 NCBI chrNW_004624801:2,296,353...2,300,853
Ensembl chrNW_004624801:2,296,168...2,301,596 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO (PMID:17234593) MGI PMID:17234593 NCBI chrNW_004624772:12,099,523...12,127,437
Ensembl chrNW_004624772:12,099,435...12,127,737 		JBrowse link
negative regulation of lipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Asxl3 ASXL transcriptional regulator 3 involved_in ISO (PMID:25450400) CACAO PMID:25450400 NCBI chrNW_004624779:8,099,434...8,270,812
Ensembl chrNW_004624779:8,144,474...8,271,269 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 acts_upstream_of_or_within ISO (PMID:28827783) MGI PMID:28827783 NCBI chrNW_004624805:5,465,699...5,574,837
Ensembl chrNW_004624805:5,465,001...5,574,291 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624740:26,627,560...26,632,483
Ensembl chrNW_004624740:26,627,473...26,632,027 		JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chrNW_004624734:7,191,049...7,204,386
Ensembl chrNW_004624734:7,191,010...7,206,020 		JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004624784:6,728,504...6,900,557
Ensembl chrNW_004624784:6,745,595...6,895,747 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624747:12,287,817...12,426,340
Ensembl chrNW_004624747:12,307,541...12,424,897 		JBrowse link
G Adora1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chrNW_004624807:7,674,164...7,705,736
Ensembl chrNW_004624807:7,674,927...7,705,051 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948198) BHF-UCL PMID:10948198 NCBI chrNW_004624737:35,262,779...35,265,566
Ensembl chrNW_004624737:35,264,099...35,265,490 		JBrowse link
G Alk ALK receptor tyrosine kinase involved_in ISO (PMID:32442405) UniProt PMID:32442405 NCBI chrNW_004624738:11,094,699...12,010,349
Ensembl chrNW_004624738:11,095,134...11,288,891 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:164,351...165,676
Ensembl chrNW_004624794:164,370...166,248 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624907:1,758,671...1,760,611
Ensembl chrNW_004624907:1,758,696...1,760,611 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chrNW_004624926:1,189,990...1,197,220
Ensembl chrNW_004624926:1,190,072...1,196,076 		JBrowse link
G Cidea cell death inducing DFFA like effector a involved_in ISO (PMID:15919794)
(PMID:12910269)
(PMID:26118629)		 BHF-UCL
UniProt		 PMID:12910269 PMID:15919794 PMID:26118629 NCBI chrNW_004624770:19,559,735...19,573,394
Ensembl chrNW_004624770:19,559,692...19,573,788 		JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:4,474,912...4,484,866
Ensembl chrNW_004624731:4,474,689...4,484,894 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (PMID:21164481) MGI PMID:21164481 NCBI chrNW_004624768:17,572,609...17,689,093
Ensembl chrNW_004624768:17,574,257...17,689,125 		JBrowse link
G Endou endonuclease, poly(U) specific involved_in ISO (PMID:37803019) FlyBase PMID:37803019 NCBI chrNW_004624816:4,526,136...4,542,530
Ensembl chrNW_004624816:4,526,487...4,541,794 		JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 homolog acts_upstream_of_or_within ISO (PMID:25912136) MGI PMID:25912136 NCBI chrNW_004624765:19,767,361...19,784,527
Ensembl chrNW_004624765:19,768,212...19,771,138 		JBrowse link
G Hcar1 hydroxycarboxylic acid receptor 1 involved_in ISO (PMID:19047060) MGI PMID:19047060 NCBI chrNW_004624747:22,792,224...22,798,189
Ensembl chrNW_004624747:22,794,256...22,795,452 		JBrowse link
G Il1b interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:14,999,088...15,000,035
Ensembl chrNW_004624767:14,999,088...15,000,035 		JBrowse link
G Pde3b phosphodiesterase 3B involved_in ISO (PMID:11641262) BHF-UCL PMID:11641262 NCBI chrNW_004624766:6,492,803...6,636,059
Ensembl chrNW_004624766:6,492,897...6,635,823 		JBrowse link
G Plin1 perilipin 1 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chrNW_004624768:16,736,435...16,750,150
Ensembl chrNW_004624768:16,735,905...16,760,326 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:21885430) UniProt PMID:21885430 NCBI chrNW_004624828:5,208,060...5,218,553
Ensembl chrNW_004624828:5,207,937...5,218,901 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (PMID:15878856) UniProt PMID:15878856 NCBI chrNW_004624759:14,143,439...14,174,971
Ensembl chrNW_004624759:14,142,956...14,171,718 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:19032770) BHF-UCL PMID:19032770 NCBI chrNW_004624754:24,623,059...24,625,647
Ensembl chrNW_004624754:24,623,425...24,625,531 		JBrowse link
negative regulation of lipoprotein lipid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D involved_in ISS UniProt GO_REF:0000024 NCBI chrNW_004624730:62,535,005...62,552,405
Ensembl chrNW_004624730:62,530,673...62,555,129 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004624865:4,220,047...4,258,014
Ensembl chrNW_004624865:4,219,081...4,258,448 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (PMID:20018880) MGI PMID:20018880 NCBI chrNW_004624751:732,364...764,421
Ensembl chrNW_004624751:730,472...764,430 		JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chrNW_004624907:1,758,671...1,760,611
Ensembl chrNW_004624907:1,758,696...1,760,611 		JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004624740:26,172,808...26,191,557
Ensembl chrNW_004624740:26,169,064...26,188,866 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004624752:9,072,471...9,088,289
Ensembl chrNW_004624752:9,072,512...9,088,593 		JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO PMID:24201375
(PMID:24201375)		 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004624756:4,585,542...4,593,285 JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) UniProt PMID:3863495 NCBI chrNW_004624751:27,543,768...27,760,536
Ensembl chrNW_004624751:27,543,702...27,759,271 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20042607) UniProt PMID:20042607 NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:33495566) UniProt PMID:33495566 NCBI chrNW_004624766:11,669,732...11,797,133
Ensembl chrNW_004624766:11,670,108...11,795,272 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (PMID:24201375) ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004624943:231,978...480,933
Ensembl chrNW_004624943:232,618...481,290 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624741:7,706,205...7,717,677
Ensembl chrNW_004624741:7,706,236...7,719,484 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004624850:3,324,553...3,481,439
Ensembl chrNW_004624850:3,322,782...3,481,512 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chrNW_004624943:483,230...505,678
Ensembl chrNW_004624943:484,942...486,390 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624800:2,533,010...2,543,754
Ensembl chrNW_004624800:2,534,967...2,543,075 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004624732:27,089,776...27,110,170
Ensembl chrNW_004624732:27,087,674...27,104,181 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of ISO (PMID:9384387) HGNC-UCL PMID:9384387 NCBI chrNW_004624762:25,759,976...25,769,543
Ensembl chrNW_004624762:25,764,452...25,769,487 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:15317892), (PMID:18182450) UniProt PMID:15317892 PMID:18182450 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within ISO (PMID:21187369) MGI PMID:21187369 NCBI chrNW_004624869:1,695,362...1,936,097
Ensembl chrNW_004624869:1,695,480...1,936,048 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004624760:880,216...898,753
Ensembl chrNW_004624760:880,148...898,751 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) UniProt PMID:18818293 NCBI chrNW_004624832:4,816,383...4,820,082
Ensembl chrNW_004624832:4,816,277...4,819,740 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:12949260) UniProt PMID:12949260 NCBI chrNW_004624764:6,913,027...6,934,650
Ensembl chrNW_004624764:6,921,811...6,933,392 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chrNW_004624750:7,222,306...7,303,809
Ensembl chrNW_004624750:7,219,251...7,303,834 		JBrowse link
G Sik1 salt inducible kinase 1 involved_in ISO (PMID:19244231) UniProt PMID:19244231 NCBI chrNW_004624745:27,529,037...27,539,253
Ensembl chrNW_004624745:27,528,929...27,539,552 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:29765047) UniProt PMID:29765047 NCBI chrNW_004624754:2,304,476...2,332,705
Ensembl chrNW_004624754:2,304,634...2,330,946 		JBrowse link
G Tmx1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624731:17,713,812...17,730,521
Ensembl chrNW_004624731:17,718,868...17,730,586 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624784:12,244,565...12,246,790
Ensembl chrNW_004624784:12,244,646...12,246,790 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chrNW_004624756:2,505,937...2,569,618
Ensembl chrNW_004624756:2,505,945...2,569,464 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chrNW_004624739:22,737,376...22,772,696
Ensembl chrNW_004624739:22,737,270...22,772,589 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chrNW_004624828:5,208,060...5,218,553
Ensembl chrNW_004624828:5,207,937...5,218,901 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:27322061) UniProt PMID:27322061 NCBI chrNW_004624880:3,579,783...3,749,958
Ensembl chrNW_004624880:3,583,838...3,749,930 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chrNW_004624860:4,938,001...4,957,640
Ensembl chrNW_004624860:4,938,001...4,957,236 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Ccnc cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004624810:5,466,972...5,485,932
Ensembl chrNW_004624810:5,466,981...5,485,930 		JBrowse link
G Cdk8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004624776:12,114,277...12,324,481
Ensembl chrNW_004624776:12,157,892...12,325,081 		JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in ISO (PMID:18682832) UniProt PMID:18682832 NCBI chrNW_004624731:4,474,912...4,484,866
Ensembl chrNW_004624731:4,474,689...4,484,894 		JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chrNW_004624785:6,164,507...6,601,302
Ensembl chrNW_004624785:6,164,379...6,601,326 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of ISO (PMID:28483554) BHF-UCL PMID:28483554 NCBI chrNW_004624849:3,602,103...3,623,922
Ensembl chrNW_004624849:3,602,261...3,623,465 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chrNW_004624790:5,509,541...5,515,240
Ensembl chrNW_004624790:5,509,311...5,515,266 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278 PMID:19502595 NCBI chrNW_004624735:6,594,564...6,598,288
Ensembl chrNW_004624735:6,594,695...6,598,757 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17640
    cellular process 17222
      negative regulation of cellular process 5032
        negative regulation of metabolic process 2774
          negative regulation of lipid metabolic process 100
            negative regulation of fatty acid metabolic process + 34
            negative regulation of isoprenoid metabolic process + 1
            negative regulation of lipid biosynthetic process + 56
            negative regulation of lipid catabolic process + 30
            negative regulation of lipoprotein lipid oxidation 1
            negative regulation of phospholipid metabolic process + 6
            negative regulation of steroid metabolic process + 27
            negative regulation of triglyceride metabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 17640
    biological regulation 11843
      regulation of biological process 11485
        regulation of cellular process 11159
          regulation of metabolic process 5978
            regulation of primary metabolic process 5026
              regulation of lipid metabolic process 343
                negative regulation of lipid metabolic process 100
                  negative regulation of fatty acid metabolic process + 34
                  negative regulation of isoprenoid metabolic process + 1
                  negative regulation of lipid biosynthetic process + 56
                  negative regulation of lipid catabolic process + 30
                  negative regulation of lipoprotein lipid oxidation 1
                  negative regulation of phospholipid metabolic process + 6
                  negative regulation of steroid metabolic process + 27
                  negative regulation of triglyceride metabolic process + 16
paths to the root