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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipid metabolic process
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Accession:GO:0045833 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
Synonyms:exact_synonym: down regulation of lipid metabolic process;   downregulation of lipid metabolic process;   negative regulation of lipid metabolism
 narrow_synonym: inhibition of lipid metabolic process

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negative regulation of lipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc2 apolipoprotein C2 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004955555:2,019,547...2,021,543
Ensembl chrNW_004955555:2,016,217...2,021,830 		JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 involved_in ISO (PMID:28827783) GO_Central PMID:28827783 NCBI chrNW_004955462:909,300...1,013,927
Ensembl chrNW_004955462:909,300...1,013,927 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955414:27,466,636...27,507,186
Ensembl chrNW_004955414:27,456,770...27,508,109 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16959810) UniProt PMID:16959810 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 ISO (PMID:12815072)
(PMID:23747249)		 UniProt
MGI		 PMID:12815072 PMID:23747249 NCBI chrNW_004955422:16,415,880...16,419,528
Ensembl chrNW_004955422:16,415,648...16,420,515 		JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chrNW_004955429:8,634,713...9,235,666
Ensembl chrNW_004955429:8,634,944...9,235,688 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) BHF-UCL PMID:16488887 NCBI chrNW_004955406:3,715,140...3,770,019
Ensembl chrNW_004955406:3,719,972...3,770,555 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chrNW_004955423:2,024,084...2,032,530
Ensembl chrNW_004955423:2,022,417...2,033,149 		JBrowse link
G LOC102011841 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chrNW_004955458:5,472,404...5,477,001
Ensembl chrNW_004955458:5,472,404...5,477,001 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chrNW_004955496:5,842,734...5,950,995
Ensembl chrNW_004955496:5,842,600...5,927,885 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ormdl1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955403:9,100,516...9,113,230
Ensembl chrNW_004955403:9,100,516...9,113,223 		JBrowse link
G Ormdl2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955458:3,451,434...3,454,259
Ensembl chrNW_004955458:3,451,021...3,457,086 		JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within ISO (PMID:25691431) MGI PMID:25691431 NCBI chrNW_004955451:14,621,565...14,627,556
Ensembl chrNW_004955451:14,621,399...14,642,763 		JBrowse link
G Sphk1 sphingosine kinase 1 involved_in ISO (PMID:16118219) UniProt PMID:16118219 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:1917954) BHF-UCL
RGD		 PMID:1917954 PMID:9225228 RGD:10059686 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888 		JBrowse link
G Chlsn cholesin involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chrNW_004955460:8,714,109...8,839,162
Ensembl chrNW_004955460:8,712,187...8,839,187 		JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955507:6,029,247...6,062,946
Ensembl chrNW_004955507:6,028,324...6,063,689 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955463:13,445,468...13,460,370
Ensembl chrNW_004955463:13,444,722...13,463,132 		JBrowse link
G Insig1 insulin induced gene 1 involved_in ISO (PMID:26311497) UniProt PMID:26311497 NCBI chrNW_004955491:8,333,624...8,344,658
Ensembl chrNW_004955491:8,335,359...8,344,658 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ch25h cholesterol 25-hydroxylase involved_in ISO (PMID:29033131) UniProt PMID:29033131 NCBI chrNW_004955425:3,763,302...3,764,432 JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955414:27,466,636...27,507,186
Ensembl chrNW_004955414:27,456,770...27,508,109 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004955483:4,495,257...4,503,377 JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:12920182), (PMID:15677334) UniProt PMID:12920182 PMID:15677334 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320 		JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chrNW_004955459:10,342,528...10,347,700
Ensembl chrNW_004955459:10,342,251...10,347,733 		JBrowse link
G Mfsd2a MFSD2 lysolipid transporter A, lysophospholipid acts_upstream_of_or_within ISO (PMID:23209793) ARUK-UCL PMID:23209793 NCBI chrNW_004955452:17,430,850...17,443,830
Ensembl chrNW_004955452:17,430,219...17,443,830 		JBrowse link
G Pink1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:21885430), (PMID:22675471)
(PMID:22532565)		 UniProt PMID:21885430 PMID:22532565 PMID:22675471 NCBI chrNW_004955495:4,406,590...4,414,783
Ensembl chrNW_004955495:4,407,246...4,416,848 		JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO (PMID:25023281)
(PMID:25416781)		 UniProt PMID:25023281 PMID:25416781 NCBI chrNW_004955411:35,999,583...36,025,805 JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004955457:5,266,032...5,300,632
Ensembl chrNW_004955457:5,266,033...5,300,056 		JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004955467:9,684,070...9,689,454
Ensembl chrNW_004955467:9,684,250...9,689,356 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:11060345), (PMID:18635818) BHF-UCL PMID:11060345 PMID:18635818 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Brca1 BRCA1 DNA repair associated involved_in ISO (PMID:16326698) UniProt PMID:16326698 NCBI chrNW_004955451:16,819,463...16,870,780
Ensembl chrNW_004955451:16,819,023...16,855,528 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955507:6,029,247...6,062,946
Ensembl chrNW_004955507:6,028,324...6,063,689 		JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) UniProt PMID:24217618 NCBI chrNW_004955463:13,445,468...13,460,370
Ensembl chrNW_004955463:13,444,722...13,463,132 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955491:8,333,624...8,344,658
Ensembl chrNW_004955491:8,335,359...8,344,658 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955459:11,571,582...11,596,069
Ensembl chrNW_004955459:11,571,145...11,592,146 		JBrowse link
G Klhl25 kelch like family member 25 involved_in ISO (PMID:27664236) UniProt PMID:27664236 NCBI chrNW_004955416:18,965,966...18,991,099 JBrowse link
G LOC102008593 cholesterol 7-alpha-monooxygenase involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chrNW_004955454:17,035,105...17,078,854
Ensembl chrNW_004955454:17,036,204...17,042,756 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (PMID:16794074) BHF-UCL PMID:16794074 NCBI chrNW_004955597:259,209...265,896
Ensembl chrNW_004955597:260,790...265,326 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO (PMID:23932781) UniProt PMID:23932781 NCBI chrNW_004955527:57,335...185,727
Ensembl chrNW_004955527:57,335...185,727 		JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 acts_upstream_of_or_within ISO (PMID:17767906) MGI PMID:17767906 NCBI chrNW_004955452:6,519,628...6,581,333
Ensembl chrNW_004955452:6,519,629...6,581,333 		JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins insulin involved_in ISO (PMID:1184755) BHF-UCL PMID:1184755 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Ncor1 nuclear receptor corepressor 1 involved_in ISO (PMID:19955185) BHF-UCL PMID:19955185 NCBI chrNW_004955467:1,408,292...1,568,539
Ensembl chrNW_004955467:1,409,281...1,546,842 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:24769897) UniProt PMID:24769897 NCBI chrNW_004955421:5,027,568...5,040,000 JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:11283375), (PMID:18487439) UniProt PMID:11283375 PMID:18487439 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076 		JBrowse link
G Acadl acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004955457:5,266,032...5,300,632
Ensembl chrNW_004955457:5,266,033...5,300,056 		JBrowse link
G Acadvl acyl-CoA dehydrogenase very long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chrNW_004955467:9,684,070...9,689,454
Ensembl chrNW_004955467:9,684,250...9,689,356 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:19661063) UniProt PMID:19661063 NCBI chrNW_004955405:39,503,020...39,540,069
Ensembl chrNW_004955405:39,503,020...39,540,335 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chrNW_004955414:16,059,781...16,089,727
Ensembl chrNW_004955414:16,059,781...16,089,727 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,882,656...11,915,875
Ensembl chrNW_004955406:11,881,882...11,916,323 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,851,694...11,875,314
Ensembl chrNW_004955406:11,851,637...11,876,843 		JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO (PMID:24792439) MGI PMID:24792439 NCBI chrNW_004955406:11,967,045...11,987,105
Ensembl chrNW_004955406:11,967,003...11,988,887 		JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(PMID:23746352)		 UniProt PMID:23746352 PMID:24043310 NCBI chrNW_004955455:11,322,812...11,334,786
Ensembl chrNW_004955455:11,324,479...11,334,817 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:32103177) UniProt PMID:32103177 NCBI chrNW_004955478:941,684...945,563
Ensembl chrNW_004955478:940,177...945,563 		JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 acts_upstream_of_or_within ISO (PMID:17234593) MGI PMID:17234593 NCBI chrNW_004955435:19,537,224...19,563,631
Ensembl chrNW_004955435:19,536,634...19,564,580 		JBrowse link
negative regulation of lipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888 		JBrowse link
G Asxl3 ASXL transcriptional regulator 3 involved_in ISO (PMID:25450400) CACAO PMID:25450400 NCBI chrNW_004955402:20,571,209...20,704,480
Ensembl chrNW_004955402:20,605,804...20,702,054 		JBrowse link
G Ccdc3 coiled-coil domain containing 3 acts_upstream_of_or_within ISO (PMID:28827783) MGI PMID:28827783 NCBI chrNW_004955462:909,300...1,013,927
Ensembl chrNW_004955462:909,300...1,013,927 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18544705) UniProt PMID:18544705 NCBI chrNW_004955555:426,894...446,235 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:23871778) UniProt PMID:23871778 NCBI chrNW_004955460:8,790,798...8,794,902
Ensembl chrNW_004955460:8,790,798...8,794,902 		JBrowse link
G Serpina12 serpin family A member 12 acts_upstream_of_or_within ISO (PMID:22837305) MGI PMID:22837305 NCBI chrNW_004955438:17,826,596...17,849,341
Ensembl chrNW_004955438:17,833,919...17,849,393 		JBrowse link
G Sik2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chrNW_004955412:13,342,032...13,458,076
Ensembl chrNW_004955412:13,342,032...13,457,563 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:15677334) UniProt PMID:15677334 NCBI chrNW_004955455:10,282,308...10,427,439
Ensembl chrNW_004955455:10,308,192...10,426,076 		JBrowse link
G Adora1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chrNW_004955406:39,148,811...39,183,577
Ensembl chrNW_004955406:39,149,689...39,187,688 		JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in ISO (PMID:10948198) BHF-UCL PMID:10948198 NCBI chrNW_004955485:384,405...387,332
Ensembl chrNW_004955485:385,800...387,240 		JBrowse link
G Alk ALK receptor tyrosine kinase involved_in ISO (PMID:32442405) UniProt PMID:32442405 NCBI chrNW_004955469:11,049,373...11,751,235
Ensembl chrNW_004955469:11,047,048...11,548,233 		JBrowse link
G Apoa2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chrNW_004955468:12,977,956...12,979,282
Ensembl chrNW_004955468:12,977,956...12,979,753 		JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chrNW_004955599:505,725...514,225
Ensembl chrNW_004955599:507,501...514,151 		JBrowse link
G Cidea cell death inducing DFFA like effector a involved_in ISO (PMID:15919794)
(PMID:12910269)
(PMID:26118629)		 BHF-UCL
UniProt		 PMID:12910269 PMID:15919794 PMID:26118629 NCBI chrNW_004955402:1,090,372...1,096,621
Ensembl chrNW_004955402:1,090,518...1,096,569 		JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in ISO (PMID:22144693), (PMID:23481402)
(PMID:18334488), (PMID:23399566)		 UniProt PMID:18334488 PMID:22144693 PMID:23399566 PMID:23481402 NCBI chrNW_004955561:1,363,907...1,376,144 JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 acts_upstream_of_or_within ISO (PMID:21164481) MGI PMID:21164481 NCBI chrNW_004955416:14,672,291...14,768,879
Ensembl chrNW_004955416:14,672,291...14,765,893 		JBrowse link
G Endou endonuclease, poly(U) specific involved_in ISO (PMID:37803019) FlyBase PMID:37803019 NCBI chrNW_004955500:6,631,749...6,653,457
Ensembl chrNW_004955500:6,632,743...6,646,657 		JBrowse link
G Fmc1 formation of mitochondrial complex V assembly factor 1 homolog acts_upstream_of_or_within ISO (PMID:25912136) MGI PMID:25912136 NCBI chrNW_004955494:3,722,359...3,730,217
Ensembl chrNW_004955494:3,722,519...3,728,622 		JBrowse link
G Hcar1 hydroxycarboxylic acid receptor 1 involved_in ISO (PMID:19047060) MGI PMID:19047060 NCBI chrNW_004955482:5,998,796...6,002,093
Ensembl chrNW_004955482:5,998,796...6,002,093 		JBrowse link
G Hcar2 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chrNW_004955482:6,007,307...6,009,353 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:19032770) BHF-UCL PMID:19032770 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Ins insulin involved_in ISO (PMID:24675707) AgBase PMID:24675707 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419 		JBrowse link
G Pde3b phosphodiesterase 3B involved_in ISO (PMID:11641262) BHF-UCL PMID:11641262 NCBI chrNW_004955414:29,783,999...29,911,329
Ensembl chrNW_004955414:29,783,963...29,909,685 		JBrowse link
G Plin1 perilipin 1 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chrNW_004955416:15,538,309...15,549,275
Ensembl chrNW_004955416:15,533,268...15,549,772 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:21885430) UniProt PMID:21885430 NCBI chrNW_004955495:4,406,590...4,414,783
Ensembl chrNW_004955495:4,407,246...4,416,848 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO (PMID:15878856) UniProt PMID:15878856 NCBI chrNW_004955426:25,079,718...25,102,090
Ensembl chrNW_004955426:25,079,718...25,102,090 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:19032770) BHF-UCL PMID:19032770 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
negative regulation of lipoprotein lipid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apod apolipoprotein D involved_in ISO (PMID:18419796) UniProt PMID:18419796 NCBI chrNW_004955420:13,553,254...13,570,357
Ensembl chrNW_004955420:13,553,058...13,573,690 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpin1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chrNW_004955487:6,139,188...6,207,316
Ensembl chrNW_004955487:6,138,926...6,210,012 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpcat1 lysophosphatidylcholine acyltransferase 1 acts_upstream_of_or_within ISO (PMID:20018880) MGI PMID:20018880 NCBI chrNW_004955504:760,941...791,996
Ensembl chrNW_004955504:758,881...791,996 		JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419 NCBI chrNW_004955555:2,005,962...2,007,239 JBrowse link
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004955460:8,328,400...8,346,755
Ensembl chrNW_004955460:8,326,891...8,346,550 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chrNW_004955413:25,150,702...25,166,987
Ensembl chrNW_004955413:25,148,062...25,166,987 		JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (PMID:24201375) ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chrNW_004955483:4,495,257...4,503,377 JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) UniProt PMID:3863495 NCBI chrNW_004955404:33,713,903...33,897,622
Ensembl chrNW_004955404:33,714,193...33,897,622 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:20042607) UniProt PMID:20042607 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prmt3 protein arginine methyltransferase 3 involved_in ISO (PMID:33495566) UniProt PMID:33495566 NCBI chrNW_004955476:1,222,579...1,331,582
Ensembl chrNW_004955476:1,223,076...1,331,582 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO PMID:24201375
(PMID:24201375)		 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chrNW_004955429:14,076,976...14,301,034
Ensembl chrNW_004955429:14,076,960...14,304,236 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650 		JBrowse link
G Hrh1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chrNW_004955429:14,022,332...14,069,931
Ensembl chrNW_004955429:14,067,405...14,068,853 		JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955491:8,333,624...8,344,658
Ensembl chrNW_004955491:8,335,359...8,344,658 		JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO (PMID:16100574) MGI PMID:16100574 NCBI chrNW_004955459:11,571,582...11,596,069
Ensembl chrNW_004955459:11,571,145...11,592,146 		JBrowse link
G Nr0b1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of ISO (PMID:9384387) HGNC-UCL PMID:9384387 NCBI chrNW_004955531:567,491...572,329
Ensembl chrNW_004955531:567,173...572,331 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:15317892), (PMID:18182450) UniProt PMID:15317892 PMID:18182450 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pde8b phosphodiesterase 8B acts_upstream_of_or_within ISO (PMID:21187369) MGI PMID:21187369 NCBI chrNW_004955425:23,512,865...23,614,326
Ensembl chrNW_004955425:23,512,151...23,635,697 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (PMID:18818293) UniProt PMID:18818293 NCBI chrNW_004955559:1,445,082...1,449,167
Ensembl chrNW_004955559:1,445,149...1,449,004 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:12949260) UniProt PMID:12949260 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chrNW_004955405:36,160,360...36,236,258
Ensembl chrNW_004955405:36,160,049...36,237,751 		JBrowse link
G Sik1 salt inducible kinase 1 involved_in ISO (PMID:19244231) UniProt PMID:19244231 NCBI chrNW_004955407:38,739,062...38,749,293
Ensembl chrNW_004955407:38,739,062...38,749,758 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:29765047) UniProt PMID:29765047 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Tmx1 thioredoxin related transmembrane protein 1 involved_in ISO (PMID:37648867) UniProt PMID:37648867 NCBI chrNW_004955409:11,708,867...11,722,205
Ensembl chrNW_004955409:11,710,646...11,722,342 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoc3 apolipoprotein C3 involved_in ISO (PMID:18635818), (PMID:3973011) BHF-UCL PMID:3973011 PMID:18635818 NCBI chrNW_004955412:18,165,667...18,168,015
Ensembl chrNW_004955412:18,165,667...18,168,015 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chrNW_004955483:2,501,751...2,552,855
Ensembl chrNW_004955483:2,502,345...2,552,689 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422 		JBrowse link
G Plin5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chrNW_004955495:4,406,590...4,414,783
Ensembl chrNW_004955495:4,407,246...4,416,848 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO (PMID:27322061) UniProt PMID:27322061 NCBI chrNW_004955412:22,421,984...22,576,179
Ensembl chrNW_004955412:22,421,984...22,576,179 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chrNW_004955413:6,471,933...6,480,475
Ensembl chrNW_004955413:6,471,953...6,480,469 		JBrowse link
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888 		JBrowse link
G Ccnc cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004955411:25,415,023...25,447,874
Ensembl chrNW_004955411:25,415,023...25,447,874 		JBrowse link
G Cdk8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chrNW_004955497:5,781,237...5,908,072
Ensembl chrNW_004955497:5,781,237...5,908,374 		JBrowse link
G Cidec cell death inducing DFFA like effector c involved_in ISO (PMID:18682832) UniProt PMID:18682832 NCBI chrNW_004955561:1,363,907...1,376,144 JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of ISO (PMID:28483554) BHF-UCL PMID:28483554 NCBI chrNW_004955577:171,425...183,669
Ensembl chrNW_004955577:171,425...186,046 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) BHF-UCL PMID:19502595 NCBI chrNW_004955445:8,232,084...8,237,893
Ensembl chrNW_004955445:8,231,924...8,237,996 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) BHF-UCL PMID:18485278 PMID:19502595 NCBI chrNW_004955454:8,759,860...8,763,603
Ensembl chrNW_004955454:8,758,636...8,764,427 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12563
    cellular process 12002
      negative regulation of cellular process 4605
        negative regulation of metabolic process 2490
          negative regulation of lipid metabolic process 102
            negative regulation of fatty acid metabolic process + 35
            negative regulation of isoprenoid metabolic process + 1
            negative regulation of lipid biosynthetic process + 56
            negative regulation of lipid catabolic process + 31
            negative regulation of lipoprotein lipid oxidation 1
            negative regulation of phospholipid metabolic process + 6
            negative regulation of steroid metabolic process + 26
            negative regulation of triglyceride metabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 12563
    biological regulation 9078
      regulation of biological process 8773
        regulation of cellular process 8486
          regulation of metabolic process 5016
            regulation of primary metabolic process 4164
              regulation of lipid metabolic process 338
                negative regulation of lipid metabolic process 102
                  negative regulation of fatty acid metabolic process + 35
                  negative regulation of isoprenoid metabolic process + 1
                  negative regulation of lipid biosynthetic process + 56
                  negative regulation of lipid catabolic process + 31
                  negative regulation of lipoprotein lipid oxidation 1
                  negative regulation of phospholipid metabolic process + 6
                  negative regulation of steroid metabolic process + 26
                  negative regulation of triglyceride metabolic process + 16
paths to the root