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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of lipid metabolic process
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Accession:GO:0045833 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
Synonyms:exact_synonym: down regulation of lipid metabolic process;   downregulation of lipid metabolic process;   negative regulation of lipid metabolism
 narrow_synonym: inhibition of lipid metabolic process


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negative regulation of lipid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:182536) BHF-UCL PMID:182536
G APOC2 apolipoprotein C2 involved_in ISO (PMID:182536) BHF-UCL PMID:182536 NCBI chr19:41,892,954...41,896,461 JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G CCDC3 coiled-coil domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:12,901,592...13,104,528
Ensembl chr10:12,875,678...13,025,280 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of androgen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23747249) Ensembl
MGI		 PMID:23747249 GO_REF:0000107 NCBI chr11:64,794,157...64,800,512
Ensembl chr11:68,085,306...68,090,028 		JBrowse link
G MALRD1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO (PMID:23747249) MGI PMID:23747249 NCBI chr10:19,461,865...19,886,155 JBrowse link
G PROX1 prospero homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:189,556,124...189,609,297
Ensembl chr 1:194,412,980...194,460,763 		JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822 		JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr 1:95,139,171...95,151,054
Ensembl chr 1:93,876,245...93,883,528 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 4:94,925,048...95,040,849
Ensembl chr 4:105,589,062...105,704,098 		JBrowse link
negative regulation of ceramide biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORMDL1 ORMDL sphingolipid biosynthesis regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr2B:77,076,432...77,090,531
Ensembl chr2B:194,996,437...195,009,102 		JBrowse link
G ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr12:33,091,020...33,093,794
Ensembl chr12:33,815,514...33,818,669 		JBrowse link
G ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25691431) MGI
Ensembl		 PMID:25691431 GO_REF:0000107 NCBI chr17:17,361,624...17,368,194
Ensembl chr17:17,581,612...17,587,741 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481 		JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO
IEA		 RGD
Ensembl		 PMID:9225228 GO_REF:0000107 RGD:10059686 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CHLSN cholesin involved_in ISO (PMID:38503280) UniProt PMID:38503280 NCBI chr 7:1,156,770...1,383,223
Ensembl chr 7:1,369,532...1,497,518 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G IDI2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (PMID:17202134) MGI PMID:17202134 NCBI chr10:1,056,280...1,062,070
Ensembl chr10:1,102,655...1,108,246 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
negative regulation of cholesterol metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CH25H cholesterol 25-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,930,638...85,932,065
Ensembl chr10:89,471,441...89,472,259 		JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G DKK3 dickkopf WNT signaling pathway inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,131,306...12,177,906
Ensembl chr11:11,824,955...11,871,139 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
negative regulation of estrogen biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829 		JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19724020 RGD:2314644 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G DBI diazepam binding inhibitor, acyl-CoA binding protein ISO RGD PMID:11485163 RGD:2316274 NCBI chr2B:6,309,048...6,314,660
Ensembl chr2B:119,887,728...119,892,986 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23209793) Ensembl
ARUK-UCL		 PMID:23209793 GO_REF:0000107 NCBI chr 1:39,244,438...39,259,156
Ensembl chr 1:40,569,706...40,584,438 		JBrowse link
G PINK1 PTEN induced kinase 1 ISO RGD PMID:25421206 RGD:11560775 NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:22532565)
(PMID:21885430), (PMID:22675471)		 UniProt PMID:21885430 PMID:22532565 PMID:22675471 NCBI chr19:3,542,675...3,555,611 JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ETFBKMT electron transfer flavoprotein subunit beta lysine methyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:54,570,372...54,586,751
Ensembl chr12:57,161,781...57,172,705 		JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417 		JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G BRCA1 BRCA1 DNA repair associated involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,197,946...14,279,064
Ensembl chr17:14,428,526...14,506,815 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G CYP7A1 cytochrome P450 family 7 subfamily A member 1 involved_in ISO PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 8:54,942,509...54,952,500
Ensembl chr 8:56,593,799...56,604,037 		JBrowse link
G DCAF5 DDB1 and CUL4 associated factor 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:49,640,440...49,743,118
Ensembl chr14:68,514,979...68,616,968 		JBrowse link
G ERLIN1 ER lipid raft associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:96,756,261...96,791,925
Ensembl chr10:100,238,320...100,273,942 		JBrowse link
G ERLIN2 ER lipid raft associated 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,034,391...37,057,164
Ensembl chr 8:34,212,704...34,233,583 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,448,130...64,486,254
Ensembl chr15:83,670,090...83,671,859 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:583,267...605,416
Ensembl chr20:359,879...375,486 		JBrowse link
G UBR4 ubiquitin protein ligase E3 component n-recognin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,032,528...18,168,954
Ensembl chr 1:19,079,779...19,215,578 		JBrowse link
G WDTC1 WD and tetratricopeptide repeats 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:17767906) MGI
Ensembl
TreeGrafter		 PMID:17767906 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:26,487,185...26,560,974
Ensembl chr 1:27,554,268...27,616,429 		JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin involved_in ISO (PMID:1184755) BHF-UCL PMID:1184755 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G NCOR1 nuclear receptor corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,934,452...35,121,195 JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain involved_in ISO (PMID:15639194) BHF-UCL PMID:15639194 NCBI chr2B:97,445,421...97,483,514
Ensembl chr2B:215,847,775...215,885,524 		JBrowse link
G ACADVL acyl-CoA dehydrogenase very long chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,249,717...7,255,165
Ensembl chr17:7,234,283...7,242,417 		JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:102,755,388...102,818,686
Ensembl chr12:106,151,969...106,206,879 		JBrowse link
G DGAT2 diacylglycerol O-acyltransferase 2 ISO RGD PMID:17526931 RGD:10400884 NCBI chr11:70,824,791...70,857,530
Ensembl chr11:74,126,169...74,158,854 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chr 1:146,742,505...146,778,560
Ensembl chr 1:150,456,729...150,492,527 		JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chr 1:146,678,858...146,704,831
Ensembl chr 1:150,393,061...150,417,295 		JBrowse link
G FMO4 flavin containing dimethylaniline monoxygenase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24792439) Ensembl
MGI		 PMID:24792439 GO_REF:0000107 NCBI chr 1:146,806,413...146,834,315
Ensembl chr 1:150,520,375...150,548,270 		JBrowse link
G SIRT4 sirtuin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (PMID:32103177) UniProt PMID:32103177 NCBI chr17:66,028,737...66,034,122 JBrowse link
negative regulation of glucocorticoid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17234593) Ensembl
MGI		 PMID:17234593 GO_REF:0000107 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
negative regulation of lipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G ASXL3 ASXL transcriptional regulator 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:26,781,382...26,953,935
Ensembl chr18:30,403,018...30,541,651 		JBrowse link
G CCDC3 coiled-coil domain containing 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28827783) Ensembl
MGI		 PMID:28827783 GO_REF:0000107 NCBI chr10:12,901,592...13,104,528
Ensembl chr10:12,875,678...13,025,280 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (PMID:18544705) UniProt PMID:18544705 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (PMID:23871778) UniProt PMID:23871778 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr14:75,110,414...75,141,569
Ensembl chr14:94,442,931...94,473,779 		JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:21084751) MGI PMID:21084751 NCBI chr11:106,484,913...106,613,711
Ensembl chr11:110,329,237...110,453,543 		JBrowse link
negative regulation of lipid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACB acetyl-CoA carboxylase beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:106,692,668...106,845,490
Ensembl chr12:110,086,374...110,239,847 		JBrowse link
G ADORA1 adenosine A1 receptor ISO RGD PMID:15220221 RGD:1625243 NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:10948198) BHF-UCL PMID:10948198 NCBI chr10:107,669,860...107,673,685 JBrowse link
G ALK ALK receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:29,196,195...29,930,062
Ensembl chr2A:29,276,041...30,006,735 		JBrowse link
G APOA2 apolipoprotein A2 involved_in ISO (PMID:14967812) BHF-UCL PMID:14967812 NCBI chr 1:136,634,754...136,636,122
Ensembl chr 1:140,546,591...140,547,959 		JBrowse link
G APOC1 apolipoprotein C1 involved_in ISO (PMID:15576844) BHF-UCL PMID:15576844
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin involved_in ISO (PMID:22269949) UniProt PMID:22269949 NCBI chr11:58,046,842...58,064,219
Ensembl chr11:61,399,314...61,416,494 		JBrowse link
G CIDEA cell death inducing DFFA like effector a involved_in ISO (PMID:15919794)
(PMID:12910269)
(PMID:26118629)		 BHF-UCL
UniProt		 PMID:12910269 PMID:15919794 PMID:26118629 NCBI chr18:2,051,880...2,075,909 JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107 		JBrowse link
G CRTC3 CREB regulated transcription coactivator 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21164481) Ensembl
MGI		 PMID:21164481 GO_REF:0000107 NCBI chr15:69,217,679...69,333,897
Ensembl chr15:88,427,468...88,533,593 		JBrowse link
G ENDOU endonuclease, poly(U) specific involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:41,003,037...41,024,127
Ensembl chr12:41,882,483...41,897,119 		JBrowse link
G FMC1 formation of mitochondrial complex V assembly factor 1 homolog acts_upstream_of_or_within ISO (PMID:25912136) MGI PMID:25912136 NCBI chr 7:131,289,119...131,295,330 JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:18465680 RGD:2293508 NCBI chr 7:142,319,479...142,326,035 JBrowse link
G HCAR1 hydroxycarboxylic acid receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:120,330,294...120,335,425
Ensembl chr12:124,567,699...124,568,739 		JBrowse link
G HCAR2 hydroxycarboxylic acid receptor 2 involved_in ISO PMID:19141678 UniProt PMID:19141678 RGD:8553927 NCBI chr12:120,305,297...120,308,463 JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G INS insulin involved_in ISO (PMID:24675707) AgBase PMID:24675707 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G LOC100994952 apolipoprotein C-I, acidic form involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:41,862,168...41,878,231 JBrowse link
G PDE3B phosphodiesterase 3B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PLIN1 perilipin 1 involved_in ISO (PMID:21701568) AgBase PMID:21701568 NCBI chr15:68,357,815...68,375,062
Ensembl chr15:87,565,468...87,577,301 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:21885430) UniProt PMID:21885430 NCBI chr19:3,542,675...3,555,611 JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:69,581,748...69,620,721
Ensembl chr 5:74,627,830...74,666,505 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
negative regulation of lipoprotein lipid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOD apolipoprotein D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:192,852,887...192,868,233
Ensembl chr 3:203,152,476...203,168,060 		JBrowse link
negative regulation of phosphatidic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPIN1 lipin 1 ISO RGD PMID:21715287 RGD:38599010 NCBI chr2A:11,664,727...11,815,497
Ensembl chr2A:11,857,961...11,961,551 		JBrowse link
negative regulation of phosphatidylcholine biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LPCAT1 lysophosphatidylcholine acyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20018880) Ensembl
MGI		 PMID:20018880 GO_REF:0000107 Ensembl chr 5:1,503,853...1,544,741 JBrowse link
negative regulation of phosphatidylcholine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC1 apolipoprotein C1 involved_in ISO (PMID:2302419) BHF-UCL PMID:2302419
negative regulation of phosphatidylinositol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883 		JBrowse link
negative regulation of phospholipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
negative regulation of progesterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in ISO (PMID:24530842) AgBase PMID:24530842 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829 		JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIBF1 progesterone immunomodulatory binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:54,011,239...54,247,952
Ensembl chr13:72,788,608...73,022,473 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKR1C3 aldo-keto reductase family 1 member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:5,079,580...5,157,572
Ensembl chr10:5,081,214...5,139,812 		JBrowse link
G PRMT3 protein arginine methyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,412,419...20,538,295
Ensembl chr11:20,324,196...20,449,681 		JBrowse link
negative regulation of sphingolipid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:25332431) MGI PMID:25332431 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
negative regulation of steroid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:6,765,161...6,777,728
Ensembl chr20:6,546,173...6,558,610 		JBrowse link
G BMP5 bone morphogenetic protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,302,721...55,425,248
Ensembl chr 6:56,936,850...57,059,519 		JBrowse link
G HRH1 histamine receptor H1 ISO RGD PMID:15917347 RGD:2316921 NCBI chr 3:11,074,451...11,199,871
Ensembl chr 3:11,541,294...11,542,757 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr 7:146,893,730...146,906,329
Ensembl chr 7:158,619,531...158,632,012 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16100574) Ensembl
MGI		 PMID:16100574 GO_REF:0000107 NCBI chr2B:5,046,971...5,068,757
Ensembl chr2B:118,632,402...118,652,647 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:9384387) HGNC-UCL
Ensembl		 PMID:9384387 GO_REF:0000107 NCBI chr  X:22,903,403...22,908,527
Ensembl chr  X:30,459,527...30,464,652 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of steroid hormone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE8B phosphodiesterase 8B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21187369) Ensembl
MGI		 PMID:21187369 GO_REF:0000107 NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743 		JBrowse link
negative regulation of steroid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO PMID:24201375 ARUK-UCL PMID:24201375 RGD:14697729 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,375,301...46,389,822
Ensembl chr19:55,301,955...55,313,690 		JBrowse link
G WNT4 Wnt family member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,310,228...21,335,985
Ensembl chr 1:22,255,056...22,268,801 		JBrowse link
negative regulation of triglyceride biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO RGD PMID:29148806 RGD:15042869 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G SIK1 salt inducible kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,675,040...29,689,408
Ensembl chr21:42,975,920...42,987,948 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,844,418...31,861,911
Ensembl chr14:50,129,568...50,147,057 		JBrowse link
negative regulation of triglyceride catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:111,667,816...111,670,861
Ensembl chr11:115,600,416...115,603,460 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (PMID:16219662) UniProt PMID:16219662 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:21435395 RGD:6482711 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614 		JBrowse link
G PLIN5 perilipin 5 involved_in ISO (PMID:22675471), (PMID:23345411) UniProt PMID:22675471 PMID:23345411 NCBI chr19:3,542,675...3,555,611 JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
negative regulation of triglyceride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 acts_upstream_of_or_within ISO (PMID:9240444) MGI PMID:9240444 NCBI chr12:7,777,734...7,793,960
Ensembl chr12:7,939,262...7,944,203 		JBrowse link
G APOE apolipoprotein E involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9240444) Ensembl
MGI		 PMID:9240444 GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G CCNC cyclin C ISO RGD PMID:22684109 RGD:9590256 NCBI chr 6:97,383,290...97,410,068
Ensembl chr 6:101,265,499...101,292,233 		JBrowse link
G CDK8 cyclin dependent kinase 8 ISO RGD PMID:22684109 RGD:9590256 NCBI chr13:7,546,922...7,698,079
Ensembl chr13:25,895,705...26,046,120 		JBrowse link
G CIDEC cell death inducing DFFA like effector c involved_in ISO (PMID:18682832) UniProt PMID:18682832 NCBI chr 3:9,811,995...9,836,069
Ensembl chr 3:10,048,554...10,173,107 		JBrowse link
G ESR1 estrogen receptor 1 ISO RGD PMID:23871901 RGD:8552990 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:28483554) Ensembl
BHF-UCL		 PMID:28483554 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:46,321,075...46,328,865
Ensembl chr20:47,384,818...47,390,733 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19447
    cellular process 19000
      negative regulation of cellular process 5607
        negative regulation of metabolic process 3243
          negative regulation of lipid metabolic process 107
            negative regulation of fatty acid metabolic process + 35
            negative regulation of isoprenoid metabolic process + 2
            negative regulation of lipid biosynthetic process + 60
            negative regulation of lipid catabolic process + 33
            negative regulation of lipoprotein lipid oxidation 1
            negative regulation of phospholipid metabolic process + 6
            negative regulation of steroid metabolic process + 28
            negative regulation of triglyceride metabolic process + 16
Path 2
Term Annotations click to browse term
  biological_process 19447
    biological regulation 11900
      regulation of biological process 11518
        regulation of cellular process 11168
          regulation of metabolic process 6637
            regulation of primary metabolic process 5234
              regulation of lipid metabolic process 360
                negative regulation of lipid metabolic process 107
                  negative regulation of fatty acid metabolic process + 35
                  negative regulation of isoprenoid metabolic process + 2
                  negative regulation of lipid biosynthetic process + 60
                  negative regulation of lipid catabolic process + 33
                  negative regulation of lipoprotein lipid oxidation 1
                  negative regulation of phospholipid metabolic process + 6
                  negative regulation of steroid metabolic process + 28
                  negative regulation of triglyceride metabolic process + 16
paths to the root