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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of action potential
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Accession:GO:0045759 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
Synonyms:exact_synonym: down regulation of action potential;   downregulation of action potential
 narrow_synonym: inhibition of action potential



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negative regulation of action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:20067581 RGD:2316187 NCBI chr 5:53,204,867...53,230,396 JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:19616018 RGD:2316192 NCBI chr 5:153,408,968...153,435,092 JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IMP RGD PMID:22884333 RGD:9686419 NCBI chr 2:49,495,771...49,899,983 JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 IMP RGD PMID:31550995 RGD:150429745 NCBI chr 3:71,553,185...71,701,377 JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO
ISS
(PMID:19223394)
GO_REF:0000024
RGD
UniProt
PMID:19223394 GO_REF:0000024 NCBI chr 9:61,078,790...61,108,697 JBrowse link
negative regulation of neuronal action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:1926253 (PMID:15456819) RGD PMID:15456819 NCBI chr 2:175,181,402...175,189,619 JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO MGI:2677631 (PMID:28768803) RGD PMID:28768803 NCBI chr 4:74,109,455...76,366,434 JBrowse link
G Gpr35 G protein-coupled receptor 35 involved_in IMP PMID:17940199 UniProt PMID:17940199 RGD:11541107 NCBI chr 9:93,527,165...93,539,573 JBrowse link
G Kcnc4 potassium voltage-gated channel subfamily C member 4 IMP RGD PMID:18048010 RGD:10412022 NCBI chr 2:195,063,967...195,100,244 JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:24836577)
Ensembl
RGD
PMID:24836577 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267 JBrowse link

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