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Pathways

ONTOLOGY REPORT - ANNOTATIONS


Term:respiratory burst
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Accession:GO:0045730 term browser browse the term
Definition:A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
Synonyms:exact_synonym: metabolic burst;   oxidative burst
 xref: Wikipedia:Respiratory_burst



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respiratory burst term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule involved_in ISO
ISS
(PMID:8223854) RGD PMID:8223854 PMID:8223854 RGD:8554386 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:48,655,805...48,661,785
JBrowse link
G Cyba cytochrome b-245 alpha chain involved_in ISO
IEA
(PMID:2243141)
GO_REF:0000107
RGD
Ensembl
PMID:2243141 GO_REF:0000107 NCBI chr19:67,396,143...67,404,214
Ensembl chr19:67,396,143...67,404,214
JBrowse link
G Cybb cytochrome b-245 beta chain involved_in ISO
IEA
(PMID:9774399)
GO_REF:0000107
RGD
Ensembl
PMID:9774399 GO_REF:0000107 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:16,030,596...16,065,065
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within
involved_in
IMP
ISO
IEA
IBA
MGI:3576788 (PMID:15626477)
GO_REF:0000117
GO_REF:0000107
GO_REF:0000033
RGD
UniProt
Ensembl
GO_Central
PMID:15626477 PMID:12461526 GO_REF:0000033 GO_REF:0000107 GO_REF:0000117, RGD:628543 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:67,505,492...67,536,015
Ensembl chr13:67,505,375...67,536,149
JBrowse link
G Ncf4 neutrophil cytosolic factor 4 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:111,705,926...111,723,893
Ensembl chr 7:111,706,520...111,723,898
JBrowse link
G Prkcq protein kinase C, theta IEP RGD PMID:10218646 RGD:1625619 NCBI chr17:72,156,215...72,288,508
Ensembl chr17:72,156,215...72,288,508
JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
(PMID:8529105)
Ensembl
RGD
PMID:8529105 GO_REF:0000107 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:83,406,427...83,417,238
JBrowse link
G Slc37a4 solute carrier family 37 member 4 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3046091 (PMID:16891306)
Ensembl
RGD
PMID:16891306 GO_REF:0000107 NCBI chr 8:53,619,952...53,626,110
Ensembl chr 8:53,620,141...53,626,110
JBrowse link
negative regulation of respiratory burst term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H IDA RGD PMID:12180124 RGD:10054105 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,841,966...93,857,127
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase acts_upstream_of_or_within ISO MGI:2154396 (PMID:7889565) RGD PMID:7889565 NCBI chr20:13,468,732...13,596,333
Ensembl chr20:13,468,732...13,596,333
JBrowse link
negative regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dusp10 dual specificity phosphatase 10 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3052343 (PMID:19696743)
Ensembl
RGD
PMID:19696743 GO_REF:0000107 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304
JBrowse link
G Grn granulin precursor involved_in ISS
ISO
GO_REF:0000024
(PMID:12526812)
UniProt
RGD
PMID:12526812 GO_REF:0000024 NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,886,122...87,893,936
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:11443198) RGD PMID:11443198 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132
JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (PMID:25799045) RGD PMID:25799045 NCBI chr13:87,580,081...87,589,941
Ensembl chr13:87,580,182...87,589,560
JBrowse link
positive regulation of respiratory burst term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk1d calcium/calmodulin-dependent protein kinase ID involved_in ISO
IEA
(PMID:15840691)
GO_REF:0000107
RGD
Ensembl
PMID:15840691 GO_REF:0000107 NCBI chr17:77,491,191...77,892,018
Ensembl chr17:77,491,220...77,892,012
JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO
IEA
(PMID:19358895)
GO_REF:0000107
RGD
Ensembl
PMID:19358895 GO_REF:0000107 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:164,588,754...164,599,919
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:9092559) RGD PMID:9092559 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:207,272,742...207,273,805
JBrowse link
G Insr insulin receptor involved_in ISO (PMID:9092559) RGD PMID:9092559 NCBI chr12:5,991,135...6,129,275
Ensembl chr12:5,981,835...6,128,803
JBrowse link
G Jchain joining chain of multimeric IgA and IgM involved_in ISO
IEA
(PMID:24145934)
GO_REF:0000107
RGD
Ensembl
PMID:24145934 GO_REF:0000107 NCBI chr14:19,822,976...19,831,072
Ensembl chr14:19,822,976...19,838,307
JBrowse link
positive regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lbp lipopolysaccharide binding protein involved_in IEA
ISO
GO_REF:0000107
(PMID:9338787)
Ensembl
RGD
PMID:9338787 GO_REF:0000107 NCBI chr 3:167,373,786...167,400,941
Ensembl chr 3:167,373,924...167,401,518
JBrowse link
G Rps19 ribosomal protein S19 involved_in ISO (PMID:15750715) RGD PMID:15750715 NCBI chr 1:89,608,408...89,614,390
Ensembl chr 7:104,324,520...104,325,132
Ensembl chr 1:104,324,520...104,325,132
JBrowse link
regulation of respiratory burst term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Noxa1 NADPH oxidase activator 1 involved_in ISO (PMID:16636067) RGD PMID:16636067 NCBI chr 3:28,293,643...28,309,828
Ensembl chr 3:28,293,658...28,304,022
JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO (PMID:16636067) RGD PMID:16636067 NCBI chr12:16,150,411...16,170,864
Ensembl chr12:16,128,649...16,172,109
JBrowse link
G Rac2 Rac family small GTPase 2 involved_in ISO
IEA
(PMID:16636067)
GO_REF:0000107
RGD
Ensembl
PMID:16636067 GO_REF:0000107 NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:111,996,742...112,009,267
JBrowse link
regulation of respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncf1 neutrophil cytosolic factor 1 IMP RGD PMID:21275845 RGD:41404729 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
JBrowse link
respiratory burst after phagocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cybc1 cytochrome b-245 chaperone 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(PMID:28351984)
GO_REF:0000107
(PMID:30361506)
UniProt
RGD
Ensembl
PMID:28351984 PMID:30361506 GO_REF:0000024 GO_REF:0000107 NCBI chr10:106,997,018...107,003,895
Ensembl chr10:106,997,023...107,003,841
JBrowse link
G Selenok selenoprotein K acts_upstream_of_or_within ISO MGI:4941878 (PMID:21220695) RGD PMID:21220695 NCBI chr16:5,158,601...5,167,183
Ensembl chr16:5,158,621...5,168,512
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) RGD PMID:30548312 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:20,144,334...20,151,779
JBrowse link
respiratory burst involved in defense response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mpo myeloperoxidase acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:2176344 (PMID:10085024)
Ensembl
RGD
PMID:10085024 GO_REF:0000107 NCBI chr10:73,092,124...73,102,057
Ensembl chr10:73,092,400...73,102,056
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:3576788 (PMID:10714686)
Ensembl
RGD
PMID:10714686 GO_REF:0000107 NCBI chr12:28,121,816...28,131,080
Ensembl chr12:28,121,366...28,131,079
JBrowse link
respiratory burst involved in inflammatory response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipa lipase A, lysosomal acid type acts_upstream_of_or_within IEA
ISO
GO_REF:0000107
MGI:6364606 (PMID:25807535), (PMID:33357458)
Ensembl
RGD
PMID:25807535 PMID:33357458 GO_REF:0000107 NCBI chr 1:241,437,524...241,470,936
Ensembl chr 1:241,437,524...241,470,740
JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:17325201) RGD PMID:17325201 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:40,084,430...40,091,006
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      metabolic process 11533
        respiratory burst 30
          negative regulation of respiratory burst + 7
          positive regulation of respiratory burst + 7
          regulation of respiratory burst + 16
          respiratory burst at fertilization 0
          respiratory burst involved in defense response + 13
paths to the root