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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of lymphocyte differentiation
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Accession:GO:0045621 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of lymphocyte differentiation;   upregulation of lymphocyte differentiation
 narrow_synonym: activation of lymphocyte differentiation;   stimulation of lymphocyte differentiation
 related_synonym: positive regulation of lymphocyte development


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positive regulation of lymphocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPP5D inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr15:133,501,067...133,626,647
Ensembl chr15:133,501,092...133,626,644 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,687,375...79,850,146
Ensembl chr 4:79,687,375...79,846,656 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in ISO (PMID:32103174) UniProt PMID:32103174 NCBI chr 5:6,903,496...6,929,162
Ensembl chr 5:6,903,495...6,929,052 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,072...52,697,900 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:121,083,750...121,090,548
Ensembl chr15:121,083,753...121,090,121 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:15064401) MGI PMID:15064401 NCBI chr10:14,362,883...14,469,586 JBrowse link
G NKAP NFKB activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:98,233,504...98,276,839
Ensembl chr  X:98,256,632...98,276,773 		JBrowse link
G PNP purine nucleoside phosphorylase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:78,426,838...78,447,029
Ensembl chr 7:78,424,740...78,447,012 		JBrowse link
G RHOA ras homolog family member A involved_in IEA
ISS		 Ensembl
AgBase		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO (PMID:7630421)
(PMID:9208839)
(PMID:9275205)		 MGI PMID:7630421 PMID:9208839 PMID:9275205 NCBI chr 3:56,515,446...56,541,806
Ensembl chr 3:56,515,449...56,541,740 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) UniProt PMID:21423173 NCBI chr  X:114,394,436...114,575,658
Ensembl chr  X:114,394,438...114,574,916 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:64,197,594...64,202,236
Ensembl chr 5:64,196,994...64,202,613 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:57,143,568...57,151,242
Ensembl chr  X:57,143,570...57,147,256 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:133,501,067...133,626,647
Ensembl chr15:133,501,092...133,626,644 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:78,541,278...78,556,784
Ensembl chr11:78,541,318...78,556,733 		JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma involved_in
acts_upstream_of_or_within		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:64,762,863...64,789,919
Ensembl chr 7:64,763,050...64,789,921 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:15,227,850...15,245,679
Ensembl chr 2:15,227,881...15,245,677 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in
acts_upstream_of_or_within		 ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 ISS
IEA		 AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD83 CD83 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:10,346,122...10,385,968
Ensembl chr 7:10,359,211...10,385,961 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:106,373,871...106,389,454
Ensembl chr  X:106,373,954...106,389,444 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:20639485) BHF-UCL PMID:20639485 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,780,404...94,796,722
Ensembl chr 4:94,780,408...94,796,657 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15778366 RGD:2303772 NCBI chr18:6,363,443...6,371,725 JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:57,143,568...57,151,242
Ensembl chr  X:57,143,570...57,147,256 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,249,009...88,291,958
Ensembl chr 7:88,262,385...88,264,691 		JBrowse link
G SLA-DRA MHC class II DR-alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,825,037...24,830,650
Ensembl chr 7:24,825,052...24,835,158 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chr12:44,155,079...44,173,634 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:27,684,320...27,750,856
Ensembl chr 6:27,684,030...27,750,852 		JBrowse link
G LOC100517285 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:18420485) ARUK-UCL PMID:18420485 NCBI chr 6:58,996,449...59,001,088 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G RUNX1 RUNX family transcription factor 1 involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chr13:198,371,835...198,635,648
Ensembl chr13:198,371,837...198,638,189 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chr 6:82,531,203...82,595,044
Ensembl chr 6:82,531,559...82,595,026 		JBrowse link
positive regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SART1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,355,690...6,373,342
Ensembl chr 2:6,354,908...6,373,272 		JBrowse link
G TNFSF9 TNF superfamily member 9 involved_in ISO
IBA		 RGD
GO_Central		 PMID:19187795 GO_REF:0000033 RGD:2317344 NCBI chr 2:72,578,811...72,582,834
Ensembl chr 2:72,578,821...72,582,745 		JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:11859104 RGD:625608 NCBI chr18:6,363,443...6,371,725 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:88,719,886...88,745,922
Ensembl chr 6:88,719,881...88,745,914 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:64,745,762...64,780,942
Ensembl chr 9:64,731,969...64,780,942 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule, complement regulatory protein involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:57,930,507...57,936,523
Ensembl chr17:57,930,432...57,936,522 		JBrowse link
G SLA-DRA MHC class II DR-alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:24,825,037...24,830,650
Ensembl chr 7:24,825,052...24,835,158 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:18713990) BHF-UCL PMID:18713990 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXL AXL receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,245,802...49,277,917
Ensembl chr 6:49,245,673...49,277,914 		JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:78,848,797...78,880,733
Ensembl chr11:78,848,797...78,881,284 		JBrowse link
G IL15 interleukin 15 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:85,666,963...85,740,980
Ensembl chr 8:85,667,321...85,678,461 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:14607906) MGI PMID:14607906 NCBI chr10:65,022,227...65,054,385 JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:101,532,742...101,540,712
Ensembl chr 8:101,532,531...101,541,713 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:132,702,495...132,786,536
Ensembl chr 1:132,702,541...132,786,532 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G TOX thymocyte selection associated high mobility group box acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:73,810,180...74,115,352
Ensembl chr 4:73,810,290...74,115,151 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,575,563...88,602,726
Ensembl chr 7:88,576,008...88,602,724 		JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:86,875,922...87,142,722
Ensembl chr 2:86,873,290...87,142,768 		JBrowse link
G AP3D1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within ISO (PMID:14557411) MGI PMID:14557411 NCBI chr 2:76,428,443...76,471,266
Ensembl chr 2:76,428,476...76,471,257 		JBrowse link
G PCD1B CD1B antigen acts_upstream_of_or_within ISO (PMID:9133426)
(PMID:10201995)		 MGI PMID:9133426 PMID:10201995 NCBI chr 4:92,035,122...92,040,724
Ensembl chr 4:92,031,712...92,040,742 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:16,784,370...16,875,828
Ensembl chr13:16,784,490...16,878,160 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,639,536...41,839,254
Ensembl chr 9:41,639,701...41,836,742 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G IL10 interleukin 10 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL2 interleukin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,575,563...88,602,726
Ensembl chr 7:88,576,008...88,602,724 		JBrowse link
positive regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,935,354...16,119,082
Ensembl chr 2:15,935,375...16,119,079 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G BTN2A2 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within ISO (PMID:23589618) MGI PMID:23589618 NCBI chr 7:20,954,229...20,968,390
Ensembl chr 7:20,954,173...20,967,794 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,265,135...28,277,641 		JBrowse link
G CD46 CD46 molecule, complement regulatory protein involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:25742728) ARUK-UCL PMID:25742728 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:10,866,446...10,905,852
Ensembl chr10:10,866,448...10,905,857 		JBrowse link
G FOXO3 forkhead box O3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,218...74,760,325 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within
involved_in		 IEA Ensembl GO_REF:0000107 NCBI chr  X:43,303,777...43,328,164
Ensembl chr  X:43,303,785...43,322,968 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:6233372 RGD:1600097 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL4I1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,906,401...54,945,840
Ensembl chr 6:54,906,406...54,916,081 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,560,544...6,572,461
Ensembl chr 2:6,560,513...6,572,466 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:25065622) UniProt PMID:25065622 NCBI chr12:44,155,079...44,173,634 JBrowse link
G LOC100517285 leukocyte immunoglobulin-like receptor subfamily A member 6 involved_in ISO (PMID:20935202), (PMID:22387553) BHF-UCL PMID:20935202 PMID:22387553 NCBI chr 6:58,996,449...59,001,088 JBrowse link
G MIR214 microRNA mir-214 ISO RGD PMID:30287503 RGD:38549580 NCBI chr 9:114,527,992...114,528,101
Ensembl chr 9:114,527,990...114,528,101 		JBrowse link
G SLA-8 MHC class I antigen 8 involved_in ISO (PMID:20448110) BHF-UCL PMID:20448110 NCBI chr 7:23,622,352...23,625,818 JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:31,879,143...31,883,041
Ensembl chr 3:31,881,225...31,884,967 		JBrowse link
G SOX12 SRY-box transcription factor 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,855,149...34,858,434
Ensembl chr17:34,857,022...34,857,960 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in ISO (PMID:24691993) UniProt PMID:24691993 NCBI chr14:74,667,081...74,693,347
Ensembl chr14:74,666,624...74,693,281 		JBrowse link
positive regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:64,197,594...64,202,236
Ensembl chr 5:64,196,994...64,202,613 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:151,402,210...151,409,924
Ensembl chr 2:151,402,211...151,409,833 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,081...34,121,264 		JBrowse link
G GATA3 GATA binding protein 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,367,684...63,397,977
Ensembl chr10:63,367,663...63,388,859 		JBrowse link
G IL12A interleukin 12A acts_upstream_of_or_within ISO (PMID:22968459) MGI PMID:22968459 NCBI chr13:99,733,394...99,741,078
Ensembl chr13:99,733,394...99,741,078 		JBrowse link
G IL1RL2 interleukin 1 receptor like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:51,978,857...52,011,607
Ensembl chr 3:51,966,691...52,011,479 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:9352365 RGD:1600138 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:9352365 RGD:1600138 NCBI chr10:64,948,149...65,001,320
Ensembl chr10:64,948,563...65,001,142 		JBrowse link
G IL4 interleukin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:53,910,999...53,971,088
Ensembl chr12:53,906,511...53,964,514 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:21,482,984...21,601,627
Ensembl chr10:21,560,073...21,601,308 		JBrowse link
G RAG1 recombination activating 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,565,447...24,573,853
Ensembl chr 2:24,561,156...24,573,851 		JBrowse link
G RHOH ras homolog family member H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:31,321,005...31,372,366
Ensembl chr 8:31,321,059...31,372,364 		JBrowse link
G SLA-DMA SLA-DM alpha chain acts_upstream_of_or_within ISO (PMID:8638109)
(PMID:8598041), (PMID:9432982)
(PMID:8598040)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr 7:25,133,494...25,137,928
Ensembl chr 7:25,133,497...25,137,966 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:14,997,377...15,013,928
Ensembl chr 5:14,997,381...15,003,567 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
G ZAP70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within ISO (PMID:7630421)
(PMID:9208839)		 MGI PMID:7630421 PMID:9208839 NCBI chr 3:56,515,446...56,541,806
Ensembl chr 3:56,515,449...56,541,740 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:88,575,563...88,602,726
Ensembl chr 7:88,576,008...88,602,724 		JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:81,409,067...81,647,808
Ensembl chr14:81,455,127...81,647,939 		JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:47,044,492...47,072,232
Ensembl chr17:47,044,497...47,072,245 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:141,221,177...141,233,728
Ensembl chr14:141,221,198...141,232,306 		JBrowse link
G EGR3 early growth response 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:6,943,184...6,948,507
Ensembl chr14:6,944,935...6,948,580 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:121,083,750...121,090,548
Ensembl chr15:121,083,753...121,090,121 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:57,143,568...57,151,242
Ensembl chr  X:57,143,570...57,147,256 		JBrowse link
G IL7R interleukin 7 receptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:21,300,141...21,330,156
Ensembl chr16:21,300,111...21,329,585 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:132,702,495...132,786,536
Ensembl chr 1:132,702,541...132,786,532 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in ISO (PMID:22561606) UniProt PMID:22561606 NCBI chr 5:19,966,623...20,017,476
Ensembl chr 5:19,904,237...20,017,433 		JBrowse link
G VNN1 vanin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,003,338...31,023,731
Ensembl chr 1:31,000,255...31,024,505 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:226,414,200...226,431,963
Ensembl chr 1:226,414,306...226,432,279 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) BHF-UCL PMID:15845453 NCBI chr10:32,110,366...32,112,529
Ensembl chr10:32,110,065...32,112,734 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:10,263,441...10,269,882
Ensembl chr10:10,264,244...10,269,879 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:47,026,558...47,075,133
Ensembl chr 4:47,027,098...47,074,704 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:93,777,402...93,925,859
Ensembl chr 3:93,783,964...93,925,863 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:162,076,933...162,144,915
Ensembl chr 1:162,076,955...162,144,880 		JBrowse link
G MIR326 microRNA mir-326 acts_upstream_of_or_within ISO (PMID:19838199) MGI PMID:19838199 NCBI chr 9:9,581,944...9,582,034
Ensembl chr 9:9,581,944...9,582,034 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr 6:45,298,289...45,307,471
Ensembl chr 6:45,298,288...45,306,316 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:157,261,419...157,273,119
Ensembl chr13:157,261,419...157,272,688 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,096,579...25,162,591
Ensembl chr 7:25,150,564...25,162,584 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr 2:62,250,958...62,345,851
Ensembl chr 2:62,250,989...62,345,362 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:21,732,416...21,733,981
Ensembl chr 5:21,732,165...21,734,267 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:130,624,771...130,718,345
Ensembl chr13:130,624,796...130,719,083 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chr 3:19,526,343...19,576,792
Ensembl chr 3:19,523,564...19,576,544 		JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,577...64,163,472 		JBrowse link
G RARA retinoic acid receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,047,449...22,085,759
Ensembl chr12:22,047,443...22,085,673 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:18354165) BHF-UCL PMID:18354165 NCBI chr 9:115,535,185...115,857,457
Ensembl chr 9:115,550,569...115,659,263 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:238,680,804...238,826,424
Ensembl chr 1:238,681,194...238,826,429 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    immune system process 2587
      leukocyte activation 1059
        lymphocyte activation 869
          lymphocyte differentiation 453
            positive regulation of lymphocyte differentiation 120
              positive regulation of B cell differentiation + 18
              positive regulation of T cell differentiation + 104
              positive regulation of natural killer cell differentiation + 10
Path 2
Term Annotations click to browse term
  biological_process 18944
    developmental process 6793
      cellular developmental process 4585
        cell differentiation 4584
          cell development 3256
            hemopoiesis 1049
              leukocyte differentiation 677
                mononuclear cell differentiation 550
                  lymphocyte differentiation 453
                    regulation of lymphocyte differentiation 212
                      positive regulation of lymphocyte differentiation 120
                        positive regulation of B cell differentiation + 18
                        positive regulation of T cell differentiation + 104
                        positive regulation of natural killer cell differentiation + 10
paths to the root