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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of lymphocyte differentiation
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Accession:GO:0045621 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of lymphocyte differentiation;   upregulation of lymphocyte differentiation
 narrow_synonym: activation of lymphocyte differentiation;   stimulation of lymphocyte differentiation
 related_synonym: positive regulation of lymphocyte development

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positive regulation of lymphocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within ISO (PMID:9620849) MGI PMID:9620849 NCBI chrNW_004624843:5,685,409...5,774,459
Ensembl chrNW_004624843:5,685,502...5,773,469 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in ISO (PMID:32103174) UniProt PMID:32103174 NCBI chrNW_004624735:7,534,483...7,702,079
Ensembl chrNW_004624735:7,534,506...7,700,305 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 involved_in ISO (PMID:32103174) UniProt PMID:32103174 NCBI chrNW_004624752:6,987,456...7,010,834
Ensembl chrNW_004624752:6,979,271...7,010,787 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11067867), (PMID:16670300)
(PMID:11067867), (PMID:12163459), (PMID:16670300)		 MGI PMID:11067867 PMID:12163459 PMID:16670300 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:15855276) BHF-UCL PMID:15855276 NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:15064401) MGI PMID:15064401 NCBI chrNW_004624807:658,334...741,018
Ensembl chrNW_004624807:658,231...741,195 		JBrowse link
G LOC101716577 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within ISO (PMID:9208839)
(PMID:9275205)
(PMID:7630421)		 MGI PMID:7630421 PMID:9208839 PMID:9275205 NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035 		JBrowse link
G Nkap NFKB activating protein involved_in ISO (PMID:19409814) UniProt PMID:19409814 NCBI chrNW_004624895:3,840,846...3,849,390 JBrowse link
G Pnp purine nucleoside phosphorylase acts_upstream_of_or_within ISO (PMID:16964310) MGI PMID:16964310 NCBI chrNW_004624825:4,688,662...4,699,912
Ensembl chrNW_004624825:4,690,831...4,700,717 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:25398325) CACAO PMID:25398325 NCBI chrNW_004624730:3,316,122...3,361,820 JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (PMID:14764698) BHF-UCL PMID:14764698 NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9275205) Ensembl
MGI		 PMID:9275205 GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) UniProt PMID:21423173 NCBI chrNW_004624808:6,778,792...6,955,259
Ensembl chrNW_004624808:6,778,794...6,952,785 		JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277 		JBrowse link
G Cd27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624860:3,199,493...3,203,683 JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:23918385)
(PMID:9252128)		 MGI PMID:9252128 PMID:23918385 NCBI chrNW_004624903:1,402,586...1,406,554
Ensembl chrNW_004624903:1,402,481...1,406,600 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:16797412) MGI PMID:16797412 NCBI chrNW_004624744:12,562,536...12,604,037
Ensembl chrNW_004624744:12,567,661...12,604,074 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10704460), (PMID:9620849) MGI
TreeGrafter		 PMID:9620849 PMID:10704460 GO_REF:0000118 NCBI chrNW_004624843:5,685,409...5,774,459
Ensembl chrNW_004624843:5,685,502...5,773,469 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISO (PMID:21572390) UniProt PMID:21572390 NCBI chrNW_004624820:9,667,371...9,677,488
Ensembl chrNW_004624820:9,667,262...9,677,774 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947) UniProt PMID:20870947 NCBI chrNW_004624793:722,743...744,824
Ensembl chrNW_004624793:722,762...744,743 		JBrowse link
G Ppp2r3c protein phosphatase 2 regulatory subunit B''gamma acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16129705) MGI
TreeGrafter		 PMID:16129705 GO_REF:0000118 NCBI chrNW_004624838:1,627,632...1,655,079
Ensembl chrNW_004624838:1,627,873...1,657,475 		JBrowse link
G Sh2d1b SH2 domain containing 1B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624787:9,077,658...9,078,053 JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:33951726) UniProt PMID:33951726 NCBI chrNW_004624767:1,376,649...1,404,382
Ensembl chrNW_004624767:1,394,704...1,404,406 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7477353)
(PMID:7477352)		 Ensembl
MGI		 PMID:7477352 PMID:7477353 GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004624747:5,123,085...5,128,465 JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd83 CD83 molecule acts_upstream_of_or_within ISO (PMID:15322158) MGI PMID:15322158 NCBI chrNW_004624756:12,212,921...12,229,974
Ensembl chrNW_004624756:12,210,892...12,229,749 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17028180) Ensembl
MGI		 PMID:17028180 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16227612) MGI
Ensembl		 PMID:16227612 GO_REF:0000107 NCBI chrNW_004624797:9,001,846...9,017,441
Ensembl chrNW_004624797:9,001,795...9,018,027 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISO (PMID:24880459) UniProt PMID:24880459 NCBI chrNW_004624824:8,444,877...8,446,628 JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:20639485) BHF-UCL PMID:20639485 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO (PMID:24880459) UniProt PMID:24880459 NCBI chrNW_004624885:2,474,427...2,489,024
Ensembl chrNW_004624885:2,475,727...2,489,030 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16301745), (PMID:18573908)
(PMID:16275384)
(PMID:12612578)		 MGI
Ensembl		 PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:16227984) MGI PMID:16227984 NCBI chrNW_004624903:1,402,586...1,406,554
Ensembl chrNW_004624903:1,402,481...1,406,600 		JBrowse link
G Klhl25 kelch like family member 25 involved_in ISO (PMID:34491895) UniProt PMID:34491895 NCBI chrNW_004624768:13,112,589...13,134,855
Ensembl chrNW_004624768:13,110,912...13,121,206 		JBrowse link
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain involved_in ISO (PMID:28467828) UniProt PMID:28467828 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:163,261...166,534
Ensembl chrNW_004624802:163,261...166,534 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) UniProt PMID:20209097 NCBI chrNW_004624786:478,048...491,086 JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chrNW_004624746:19,204,415...19,264,217
Ensembl chrNW_004624746:19,204,392...19,264,194 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chrNW_004624764:9,192,067...9,218,617
Ensembl chrNW_004624764:9,191,556...9,248,252 		JBrowse link
positive regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP involved_in ISO (PMID:10209962) UniProt PMID:10209962 NCBI chrNW_004624767:20,456,951...20,466,994
Ensembl chrNW_004624767:20,456,890...20,467,641 		JBrowse link
G Tnfsf9 TNF superfamily member 9 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:19187795 GO_REF:0000118 RGD:2317344 NCBI chrNW_004624828:3,615,860...3,623,377 JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO (PMID:7807014) MGI PMID:7807014 NCBI chrNW_004624764:15,469,582...15,495,351
Ensembl chrNW_004624764:15,472,685...15,495,351 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISO (PMID:23562159) UniProt PMID:23562159 NCBI chrNW_004624830:1,320,034...1,422,774
Ensembl chrNW_004624830:1,321,387...1,424,389 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624904:2,508,576...2,575,505
Ensembl chrNW_004624904:2,508,799...2,578,609 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:7807014) MGI PMID:7807014 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in ISO (PMID:23562159) UniProt PMID:23562159 NCBI chrNW_004624807:6,848,218...6,887,666
Ensembl chrNW_004624807:6,848,218...6,888,467 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:23562159) UniProt PMID:23562159 NCBI chrNW_004624756:5,128,848...5,156,174 JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7477352)
(PMID:8790395)		 Ensembl
MGI		 PMID:7477352 PMID:8790395 GO_REF:0000107 NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418 		JBrowse link
G LOC101706353 HLA class II histocompatibility antigen, DR alpha chain involved_in ISO (PMID:27591323) UniProt PMID:27591323 NCBI chrNW_004624754:24,079,459...24,086,342
Ensembl chrNW_004624754:24,079,366...24,084,512 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISO (PMID:29230018) UniProt PMID:29230018 NCBI chrNW_004624741:23,985,257...23,990,354
Ensembl chrNW_004624741:23,985,675...23,989,790 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18713990) BHF-UCL PMID:18713990 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl AXL receptor tyrosine kinase involved_in ISO (PMID:18840707) UniProt PMID:18840707 NCBI chrNW_004624907:76,236...106,765
Ensembl chrNW_004624907:77,806...106,228 		JBrowse link
G Flt3lg fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO (PMID:14607906) MGI PMID:14607906 NCBI chrNW_004624832:4,733,820...4,739,214 JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO (PMID:18840707) UniProt PMID:18840707 NCBI chrNW_004624793:385,846...410,934
Ensembl chrNW_004624793:385,812...410,934 		JBrowse link
G Il15 interleukin 15 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14607906)
(PMID:17318811)		 Ensembl
MGI		 PMID:14607906 PMID:17318811 GO_REF:0000107 NCBI chrNW_004624853:1,059,625...1,144,799
Ensembl chrNW_004624853:1,128,519...1,144,941 		JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:14607906) MGI PMID:14607906 NCBI chrNW_004624775:846,063...877,894
Ensembl chrNW_004624775:847,677...877,604 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (PMID:14764669) MGI PMID:14764669 NCBI chrNW_004624777:3,054,368...3,061,304
Ensembl chrNW_004624777:3,054,368...3,061,304 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624804:5,691,011...5,763,314
Ensembl chrNW_004624804:5,690,400...5,763,288 		JBrowse link
G Tox thymocyte selection associated high mobility group box acts_upstream_of_or_within ISO (PMID:20818394) MGI PMID:20818394 NCBI chrNW_004624744:32,865,781...33,218,453
Ensembl chrNW_004624744:32,865,720...33,218,643 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (PMID:22753936) UniProt PMID:22753936 NCBI chrNW_004624734:36,479,670...36,509,655 JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO (PMID:14557411) MGI PMID:14557411 NCBI chrNW_004624869:2,459,370...2,741,529
Ensembl chrNW_004624869:2,459,947...2,741,328 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within ISO (PMID:14557411) MGI PMID:14557411 NCBI chrNW_004624828:6,710,081...6,750,315
Ensembl chrNW_004624828:6,710,025...6,749,434 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 acts_upstream_of_or_within ISO (PMID:16973387) MGI PMID:16973387 NCBI chrNW_004624788:8,447,679...8,535,821
Ensembl chrNW_004624788:8,447,542...8,535,959 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:9,545,529...9,726,960
Ensembl chrNW_004624784:9,546,509...9,726,960 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:30842412) UniProt PMID:30842412 NCBI chrNW_004624741:4,292,256...4,305,424
Ensembl chrNW_004624741:4,292,256...4,305,504 		JBrowse link
G Il10 interleukin 10 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:22962438) ARUK-UCL
Ensembl		 PMID:22962438 GO_REF:0000107 NCBI chrNW_004624807:4,687,249...4,691,658
Ensembl chrNW_004624807:4,687,176...4,691,732 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004624747:5,123,085...5,128,465 JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (PMID:22753936) UniProt PMID:22753936 NCBI chrNW_004624734:36,479,670...36,509,655 JBrowse link
positive regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO (PMID:30513302) UniProt PMID:30513302 NCBI chrNW_004624767:1,967,002...2,160,102
Ensembl chrNW_004624767:1,966,898...2,160,465 		JBrowse link
G Bcl6 BCL6 transcription repressor involved_in ISO (PMID:20935202), (PMID:22387553) BHF-UCL PMID:20935202 PMID:22387553 NCBI chrNW_004624730:69,145,035...69,167,583
Ensembl chrNW_004624730:69,154,080...69,167,689 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chrNW_004624746:18,692,179...18,704,952
Ensembl chrNW_004624746:18,692,225...18,704,476 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chrNW_004624807:4,040,639...4,074,631 JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO (PMID:22387553) BHF-UCL PMID:22387553 NCBI chrNW_004624835:4,751,651...4,783,916
Ensembl chrNW_004624835:4,750,077...4,782,249 		JBrowse link
G Foxo3 forkhead box O3 involved_in ISO (PMID:30513302) UniProt PMID:30513302 NCBI chrNW_004624780:13,621,733...13,740,399
Ensembl chrNW_004624780:13,622,948...13,740,374 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15780990)
(PMID:12522256), (PMID:15100250), (PMID:16769892), (PMID:17028180)		 Ensembl
MGI		 PMID:12522256 PMID:15100250 PMID:15780990 PMID:16769892 PMID:17028180 GO_REF:0000107 NCBI chrNW_004624893:995,145...1,008,492
Ensembl chrNW_004624893:995,182...1,008,679 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:6233372 RGD:1600097 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:25778793) UniProt PMID:25778793 NCBI chrNW_004624832:4,404,818...4,444,551
Ensembl chrNW_004624832:4,431,903...4,444,651 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISO (PMID:24835996) UniProt PMID:24835996 NCBI chrNW_004624767:20,668,759...20,675,367
Ensembl chrNW_004624767:20,666,763...20,675,164 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:25065622) UniProt PMID:25065622 NCBI chrNW_004624786:478,048...491,086 JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISO (PMID:22387553) BHF-UCL PMID:22387553 NCBI chrNW_004624824:8,444,877...8,446,628 JBrowse link
G Sox12 SRY-box transcription factor 12 involved_in ISO (PMID:30190287) UniProt PMID:30190287 NCBI chrNW_004624741:1,428,233...1,432,372
Ensembl chrNW_004624741:1,428,241...1,431,025 		JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in ISO (PMID:25065622) UniProt PMID:25065622 NCBI chrNW_004624907:162,567...175,696
Ensembl chrNW_004624907:161,569...176,605 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) UniProt PMID:24691993 NCBI chrNW_004624754:5,664,899...5,686,675
Ensembl chrNW_004624754:5,665,445...5,686,692 		JBrowse link
positive regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:9478961)
(PMID:7731963)		 MGI PMID:7731963 PMID:9478961 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Bad BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chrNW_004624767:22,025,721...22,037,283
Ensembl chrNW_004624767:22,026,133...22,037,277 		JBrowse link
G Cd27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624860:3,199,493...3,203,683 JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:9432982)
(PMID:7679955), (PMID:8598040)		 MGI PMID:7679955 PMID:8598040 PMID:9432982 NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO (PMID:16501569) MGI PMID:16501569 NCBI chrNW_004624757:5,895,912...5,953,485 JBrowse link
G Gata3 GATA binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392 		JBrowse link
G Il12a interleukin 12A acts_upstream_of_or_within ISO (PMID:22968459) MGI PMID:22968459 NCBI chrNW_004624730:37,787,772...37,794,871
Ensembl chrNW_004624730:37,787,909...37,794,940 		JBrowse link
G Il1rl2 interleukin 1 receptor like 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22968459) Ensembl
MGI		 PMID:22968459 GO_REF:0000107 NCBI chrNW_004624749:6,747,131...6,781,908
Ensembl chrNW_004624749:6,749,007...6,779,753 		JBrowse link
G Il2 interleukin 2 ISO RGD PMID:9352365 RGD:1600138 NCBI chrNW_004624777:2,885,537...2,890,453
Ensembl chrNW_004624777:2,885,535...2,890,453 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha ISO RGD PMID:9352365 RGD:1600138 NCBI chrNW_004624775:927,337...991,062
Ensembl chrNW_004624775:924,648...942,354 		JBrowse link
G Il36b interleukin 36 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22968459) MGI
TreeGrafter		 PMID:22968459 GO_REF:0000118 NCBI chrNW_004624749:13,107,596...13,128,883 JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) UniProt PMID:20554961 NCBI chrNW_004624733:39,412,800...39,420,079 JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chrNW_004624744:12,562,536...12,604,037
Ensembl chrNW_004624744:12,567,661...12,604,074 		JBrowse link
G LOC101700274 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8598041), (PMID:9432982)
(PMID:8638109)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chrNW_004624754:23,752,352...23,765,319
Ensembl chrNW_004624754:23,762,051...23,765,593 		JBrowse link
G LOC101716577 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within ISO (PMID:9208839)
(PMID:7630421)		 MGI PMID:7630421 PMID:9208839 NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035 		JBrowse link
G Mdk midkine involved_in ISO (PMID:28183532) UniProt PMID:28183532 NCBI chrNW_004624767:2,171,096...2,173,436
Ensembl chrNW_004624767:2,171,096...2,173,512 		JBrowse link
G Pik3r6 phosphoinositide-3-kinase regulatory subunit 6 involved_in ISO (PMID:12707323) CACAO PMID:12707323 NCBI chrNW_004624786:11,324,558...11,386,202
Ensembl chrNW_004624786:11,326,364...11,371,767 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8666928) MGI PMID:8666928 NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656 		JBrowse link
G Rag1 recombination activating 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:10,694,867...10,698,041
Ensembl chrNW_004624767:10,694,867...10,698,001 		JBrowse link
G Rhoh ras homolog family member H involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624761:26,717,857...26,721,628
Ensembl chrNW_004624761:26,720,478...26,721,053 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:19723499) MGI PMID:19723499 NCBI chrNW_004624816:3,221,573...3,227,102
Ensembl chrNW_004624816:3,210,828...3,227,096 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO (PMID:11460154) UniProt PMID:11460154 NCBI chrNW_004624747:5,123,085...5,128,465 JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (PMID:22201126) UniProt PMID:22201126 NCBI chrNW_004624734:36,479,670...36,509,655 JBrowse link
G Zmiz1 zinc finger MIZ-type containing 1 involved_in ISO (PMID:26522984) UniProt PMID:26522984 NCBI chrNW_004624754:12,106,828...12,299,188
Ensembl chrNW_004624754:12,145,570...12,299,318 		JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within ISO (PMID:11067867), (PMID:16670300)
(PMID:11435465)
(PMID:11067867), (PMID:12163459), (PMID:16670300)		 MGI PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 NCBI chrNW_004624790:9,809,550...9,829,199
Ensembl chrNW_004624790:9,809,492...9,829,883 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in ISO (PMID:20856819) BHF-UCL PMID:20856819 NCBI chrNW_004624737:13,459,274...13,474,686 JBrowse link
G Egr3 early growth response 3 acts_upstream_of_or_within ISO (PMID:21737317) MGI PMID:21737317 NCBI chrNW_004624758:18,180,787...18,186,148
Ensembl chrNW_004624758:18,180,123...18,186,196 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:5,959,329...5,965,584
Ensembl chrNW_004624823:5,959,448...5,964,769 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO (PMID:9916699)
(PMID:9252128)		 MGI PMID:9252128 PMID:9916699 NCBI chrNW_004624903:1,402,586...1,406,554
Ensembl chrNW_004624903:1,402,481...1,406,600 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO (PMID:9215626) MGI PMID:9215626 NCBI chrNW_004624759:19,067,933...19,103,007
Ensembl chrNW_004624759:19,067,856...19,098,859 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624804:5,691,011...5,763,314
Ensembl chrNW_004624804:5,690,400...5,763,288 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (PMID:19109233) BHF-UCL PMID:19109233 NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068 		JBrowse link
G Tespa1 thymocyte expressed, positive selection associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624983:31,552...47,575
Ensembl chrNW_004624983:31,766...45,077 		JBrowse link
G Vnn1 vanin 1 involved_in ISO (PMID:8934567) BHF-UCL PMID:8934567 NCBI chrNW_004624753:6,869,269...6,892,217
Ensembl chrNW_004624753:6,867,953...6,892,186 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISO (PMID:17008549) UniProt PMID:17008549 NCBI chrNW_004624811:765,338...782,203
Ensembl chrNW_004624811:764,940...782,198 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) BHF-UCL PMID:15845453 NCBI chrNW_004624736:39,088,741...39,090,745
Ensembl chrNW_004624736:39,088,921...39,090,394 		JBrowse link
G Hlx H2.0 like homeobox acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004624835:4,223,252...4,227,892
Ensembl chrNW_004624835:4,223,511...4,227,979 		JBrowse link
G Ripk2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO (PMID:11894097) MGI PMID:11894097 NCBI chrNW_004624744:2,194,339...2,227,498
Ensembl chrNW_004624744:2,201,319...2,226,890 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624738:28,150,004...28,217,850
Ensembl chrNW_004624738:28,150,664...28,216,389 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004624792:4,148,258...4,223,431
Ensembl chrNW_004624792:4,148,453...4,217,548 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004624794:10,172,789...10,180,693
Ensembl chrNW_004624794:10,168,792...10,179,510 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chrNW_004624789:15,612,311...15,623,878
Ensembl chrNW_004624789:15,612,335...15,624,152 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chrNW_004624937:564,191...584,470 JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chrNW_004624754:23,742,506...23,750,668
Ensembl chrNW_004624754:23,742,509...23,750,062 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chrNW_004624901:2,348,218...2,434,429
Ensembl chrNW_004624901:2,346,734...2,380,852 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418 		JBrowse link
G Opa1 OPA1 mitochondrial dynamin like GTPase involved_in ISO (PMID:36171294) UniProt PMID:36171294 NCBI chrNW_004624730:63,911,066...63,994,886
Ensembl chrNW_004624730:63,911,066...63,995,596 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624784:7,294,286...7,312,959
Ensembl chrNW_004624784:7,294,183...7,304,687 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 NCBI chrNW_004624782:11,981,781...12,008,362 JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318 		JBrowse link
G Nlrp3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chrNW_004624937:564,191...584,470 JBrowse link
G Prkcz protein kinase C zeta involved_in ISO (PMID:15987782) UniProt PMID:15987782 NCBI chrNW_004624818:7,758,192...7,846,950
Ensembl chrNW_004624818:7,759,770...7,847,208 		JBrowse link
G Rara retinoic acid receptor alpha involved_in ISO (PMID:18416830) BHF-UCL PMID:18416830 NCBI chrNW_004624795:2,935,432...2,975,226
Ensembl chrNW_004624795:2,934,731...2,967,232 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18354165) BHF-UCL PMID:18354165 NCBI chrNW_004624771:8,580,489...8,599,735 JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within ISO (PMID:24645804) MGI PMID:24645804 NCBI chrNW_004624825:3,846,604...3,972,780
Ensembl chrNW_004624825:3,845,092...3,973,636 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17653
    immune system process 2285
      leukocyte activation 927
        lymphocyte activation 752
          lymphocyte differentiation 403
            positive regulation of lymphocyte differentiation 111
              positive regulation of B cell differentiation + 17
              positive regulation of T cell differentiation + 93
              positive regulation of natural killer cell differentiation + 9
Path 2
Term Annotations click to browse term
  biological_process 17653
    developmental process 6427
      cellular developmental process 4326
        cell differentiation 4325
          cell development 3071
            hemopoiesis 949
              leukocyte differentiation 611
                mononuclear cell differentiation 495
                  lymphocyte differentiation 403
                    regulation of lymphocyte differentiation 191
                      positive regulation of lymphocyte differentiation 111
                        positive regulation of B cell differentiation + 17
                        positive regulation of T cell differentiation + 93
                        positive regulation of natural killer cell differentiation + 9
paths to the root