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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of lymphocyte differentiation
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Accession:GO:0045621 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: up regulation of lymphocyte differentiation;   upregulation of lymphocyte differentiation
 narrow_synonym: activation of lymphocyte differentiation;   stimulation of lymphocyte differentiation
 related_synonym: positive regulation of lymphocyte development


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positive regulation of lymphocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INPP5D inositol polyphosphate-5-phosphatase D acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:44,201,391...44,386,803
Ensembl chr 8:41,593,029...41,778,299 		JBrowse link
G XRCC6 X-ray repair cross complementing 6 involved_in ISO (PMID:32103174) UniProt PMID:32103174 NCBI chr22:22,516,281...22,557,379
Ensembl chr22:40,603,038...40,643,314 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:202,091,263...202,198,880
Ensembl chr 1:207,084,883...207,191,678 		JBrowse link
G LOC100971372 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088 		JBrowse link
G NKAP NFKB activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:108,988,561...109,006,946
Ensembl chr  X:119,384,655...119,402,775 		JBrowse link
G PNP purine nucleoside phosphorylase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:1,343,921...1,351,670
Ensembl chr14:19,396,114...19,403,907 		JBrowse link
G RHOA ras homolog family member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) UniProt PMID:21423173 NCBI chr  X:128,880,747...129,085,989
Ensembl chr  X:139,132,783...139,334,869 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:60,375,815...60,386,936
Ensembl chr  X:70,433,360...70,437,590 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:120,287,606...120,436,526
Ensembl chr2B:239,201,762...239,350,190 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251 		JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma involved_in
acts_upstream_of_or_within		 IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:15,834,603...15,871,741
Ensembl chr14:34,020,893...34,056,842 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,301,245...47,326,891
Ensembl chr11:47,853,991...47,880,259 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in		 IEA Ensembl GO_REF:0000107 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD83 CD83 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:13,961,342...13,980,686
Ensembl chr 6:14,330,752...14,349,946 		JBrowse link
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G SASH3 SAM and SH3 domain containing 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:118,909,980...118,924,779
Ensembl chr  X:129,207,049...129,222,342 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISO (PMID:24880459) UniProt PMID:24880459 NCBI chr16:10,196,432...10,198,205 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:20639485) BHF-UCL PMID:20639485 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,350,798...130,366,690
Ensembl chr 1:133,959,847...133,975,729 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FOXP3 forkhead box P3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029 		JBrowse link
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:15778366 RGD:2303772 NCBI chr 7:142,319,479...142,326,035 JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:60,375,815...60,386,936
Ensembl chr  X:70,433,360...70,437,590 		JBrowse link
G KLHL25 kelch like family member 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:64,448,130...64,486,254
Ensembl chr15:83,670,090...83,671,859 		JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G LOC100977210 galectin-9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC117976679 galectin-9B involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:35,781,679...35,790,573 JBrowse link
G LOC129394382 galectin-9B-like involved_in IEA Ensembl GO_REF:0000107
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBFB core-binding factor subunit beta involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chr16:47,373,543...47,446,783 JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) ARUK-UCL PMID:18420485 NCBI chr19:51,606,681...51,612,751 JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G RUNX3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) UniProt PMID:18258917 NCBI chr 1:24,097,321...24,164,065
Ensembl chr 1:25,073,134...25,137,335 		JBrowse link
positive regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SART1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,326,262...61,343,475
Ensembl chr11:64,654,470...64,670,720 		JBrowse link
G TNFSF9 TNF superfamily member 9 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:19187795 GO_REF:0000118 RGD:2317344 NCBI chr19:5,558,021...5,562,901
Ensembl chr19:6,476,941...6,483,352 		JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GIMAP5 GTPase, IMAP family member 5 ISO RGD PMID:11859104 RGD:625608 NCBI chr 7:142,319,479...142,326,035 JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,552,959...100,674,156
Ensembl chr 4:111,125,312...111,245,980 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:34,200,102...34,249,873
Ensembl chr12:34,932,470...34,977,881 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G SOX13 SRY-box transcription factor 13 involved_in ISO (PMID:23562159) UniProt PMID:23562159 NCBI chr 1:179,675,017...179,730,628
Ensembl chr 1:184,003,907...184,016,504 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISO (PMID:23562159) UniProt PMID:23562159 NCBI chr 6:21,422,846...21,427,779 JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617 		JBrowse link
G LOC100987081 HLA class II histocompatibility antigen, DR alpha chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,105,421...32,110,579
Ensembl chr 6:32,982,228...32,987,417 		JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920 		JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:18713990) BHF-UCL PMID:18713990 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845 		JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXL AXL receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,211,555...38,254,464
Ensembl chr19:46,719,615...46,761,747 		JBrowse link
G FLT3LG fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO (PMID:14607906) MGI PMID:14607906 NCBI chr19:46,486,169...46,499,008 JBrowse link
G GAS6 growth arrest specific 6 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr13:113,968,843...114,009,562 JBrowse link
G IL15 interleukin 15 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:133,693,995...134,115,470
Ensembl chr 4:145,402,111...145,416,622 		JBrowse link
G IL15RA interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO (PMID:14607906) MGI PMID:14607906 NCBI chr10:5,993,583...6,019,967 JBrowse link
G IL21 interleukin 21 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:114,795,979...114,806,936
Ensembl chr 4:125,943,495...125,951,915 		JBrowse link
G LOC100988550 signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,005,025...15,029,110
Ensembl chr17:15,228,465...15,251,783 		JBrowse link
G LOC100989105 signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:15,040,303...15,116,682
Ensembl chr17:15,306,418...15,336,463 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G TOX thymocyte selection associated high mobility group box acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:55,246,933...55,553,839
Ensembl chr 8:56,922,773...57,219,410 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403 		JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP3B1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205 		JBrowse link
G AP3D1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:1,110,419...1,161,826
Ensembl chr19:2,085,540...2,137,593 		JBrowse link
G CD1D CD1d molecule acts_upstream_of_or_within ISO (PMID:9133426)
(PMID:10201995)		 MGI PMID:9133426 PMID:10201995 NCBI chr 1:133,549,258...133,557,752
Ensembl chr 1:137,341,690...137,348,173 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:30,536,187...30,623,653
Ensembl chr 3:30,854,460...30,938,856 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:108,938,414...109,133,819
Ensembl chr11:112,780,380...112,977,164 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G IL10 interleukin 10 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G IL2 interleukin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403 		JBrowse link
positive regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AMBRA1 autophagy and beclin 1 regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,355,026...46,556,091
Ensembl chr11:46,905,454...47,103,205 		JBrowse link
G BCL6 BCL6 transcription repressor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:184,748,135...184,772,375
Ensembl chr 3:193,308,296...193,332,124 		JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO (PMID:23793062) MGI PMID:23793062 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709 		JBrowse link
G CD46 CD46 molecule involved_in ISO (PMID:12540904) UniProt PMID:12540904 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:25742728) ARUK-UCL PMID:25742728 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G DUSP10 dual specificity phosphatase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:197,293,039...197,333,828
Ensembl chr 1:202,367,318...202,404,720 		JBrowse link
G FOXO3 forkhead box O3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,360,519...106,485,676
Ensembl chr 6:110,406,266...110,516,272 		JBrowse link
G FOXP3 forkhead box P3 involved_in
acts_upstream_of_or_within		 IEA Ensembl GO_REF:0000107 NCBI chr  X:41,550,462...41,567,492
Ensembl chr  X:49,402,652...49,417,029 		JBrowse link
G IL2 interleukin 2 ISO RGD PMID:6233372 RGD:1600097 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984 		JBrowse link
G IL4I1 interleukin 4 induced 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,902,656...46,942,213
Ensembl chr19:55,819,080...55,858,389 		JBrowse link
G KAT5 lysine acetyltransferase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:61,071,118...61,078,667
Ensembl chr11:64,404,572...64,412,667 		JBrowse link
G LILRB4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:20935202), (PMID:22387553) BHF-UCL PMID:20935202 PMID:22387553 NCBI chr19:51,606,681...51,612,751 JBrowse link
G LOC100975566 butyrophilin subfamily 2 member A2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:26,215,215...26,227,261
Ensembl chr 6:26,873,828...26,885,592 		JBrowse link
G LOC100977210 galectin-9 involved_in ISO (PMID:25065622) UniProt PMID:25065622 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC100978774 patr class I histocompatibility antigen, alpha chain G involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,616,091...29,620,270
Ensembl chr 6:30,286,395...30,390,865 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 involved_in ISO (PMID:22387553) BHF-UCL PMID:22387553 NCBI chr16:10,196,432...10,198,205 JBrowse link
G SOX12 SRY-box transcription factor 12 involved_in ISO (PMID:30190287) UniProt PMID:30190287 NCBI chr20:533,901...537,106 JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:38,324,009...38,347,003
Ensembl chr19:46,831,659...46,852,973 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613 		JBrowse link
positive regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr12:6,575,104...6,582,127
Ensembl chr12:6,492,119...6,499,427 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:31,004,393...31,064,546
Ensembl chr16:49,882,751...49,942,629 		JBrowse link
G GATA3 GATA binding protein 3 involved_in ISO (PMID:20696860) UniProt PMID:20696860 NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272 		JBrowse link
G IL12A interleukin 12A acts_upstream_of_or_within ISO (PMID:22968459) MGI PMID:22968459 NCBI chr 3:157,011,675...157,019,897
Ensembl chr 3:165,061,505...165,068,666 		JBrowse link
G IL1RL2 interleukin 1 receptor like 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr2A:103,237,996...103,289,414 JBrowse link
G IL2 interleukin 2 ISO RGD PMID:9352365 RGD:1600138 NCBI chr 4:114,637,328...114,642,586
Ensembl chr 4:125,782,563...125,787,984 		JBrowse link
G IL2RA interleukin 2 receptor subunit alpha ISO RGD PMID:9352365 RGD:1600138 NCBI chr10:6,053,549...6,103,863 JBrowse link
G IL4 interleukin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:75,254,166...75,337,373
Ensembl chr 8:76,895,095...76,966,918 		JBrowse link
G LOC100968989 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598041), (PMID:9432982)
(PMID:8638109)
(PMID:8598040)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr 6:32,518,060...32,537,989
Ensembl chr 6:33,634,123...33,637,988 		JBrowse link
G LOC100971372 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088 		JBrowse link
G MDK midkine involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,782,422...42,851,692
Ensembl chr17:47,518,629...47,585,160 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G RAG1 recombination activating 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
G RHOH ras homolog family member H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:34,517,487...34,569,934
Ensembl chr 4:40,419,549...40,420,124 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:39,771,163...39,785,411
Ensembl chr12:40,659,106...40,665,734 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
G ZBTB1 zinc finger and BTB domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,085,146...45,114,965
Ensembl chr14:63,354,458...63,359,403 		JBrowse link
G ZMIZ1 zinc finger MIZ-type containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:75,581,794...75,829,748
Ensembl chr10:78,294,867...78,492,475 		JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADA adenosine deaminase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:40,950,238...40,982,481
Ensembl chr20:42,044,613...42,076,868 		JBrowse link
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,172,724...134,186,227 JBrowse link
G EGR3 early growth response 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:21,937,516...21,943,646
Ensembl chr 8:18,877,396...18,882,874 		JBrowse link
G IHH Indian hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:106,312,472...106,319,124
Ensembl chr2B:224,906,271...224,911,506 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:60,375,815...60,386,936
Ensembl chr  X:70,433,360...70,437,590 		JBrowse link
G IL7R interleukin 7 receptor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:74,489,188...74,516,330
Ensembl chr 5:79,769,859...79,792,612 		JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G TESPA1 thymocyte expressed, positive selection associated 1 involved_in ISO (PMID:22561606) UniProt PMID:22561606 NCBI chr12:33,765,283...33,800,883
Ensembl chr12:34,492,311...34,527,627 		JBrowse link
G VNN1 vanin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:130,459,268...130,491,167
Ensembl chr 6:134,566,117...134,598,784 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779 		JBrowse link
G CCL19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) BHF-UCL PMID:15845453 NCBI chr 9:34,525,820...34,527,628
Ensembl chr 9:35,334,353...35,336,108 		JBrowse link
G HLX H2.0 like homeobox acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:196,465,704...196,471,803
Ensembl chr 1:201,500,470...201,506,222 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) UniProt PMID:12242343 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MALT1 MALT1 paracaspase involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574 		JBrowse link
G NFKBID NFKB inhibitor delta involved_in ISO (PMID:25282160) UniProt PMID:25282160 NCBI chr19:32,805,772...32,817,778
Ensembl chr19:41,553,727...41,568,555 		JBrowse link
G NFKBIZ NFKB inhibitor zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:98,914,957...98,948,467
Ensembl chr 3:105,616,645...105,628,300 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BRD2 bromodomain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:32,538,130...32,550,823
Ensembl chr 6:33,657,648...33,666,031 		JBrowse link
G BRD4 bromodomain containing 4 involved_in ISO (PMID:28262505) UniProt PMID:28262505 NCBI chr19:14,768,239...14,805,770
Ensembl chr19:15,754,930...15,789,600 		JBrowse link
G EP300 E1A binding protein p300 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G IL23A interleukin 23 subunit alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:32,575,321...32,576,856
Ensembl chr12:32,828,902...32,830,617 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:190,890,242...190,995,133
Ensembl chr 3:201,207,607...201,312,358 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:107,024,376...107,045,194
Ensembl chr11:110,867,586...110,888,371 		JBrowse link
G IL4R interleukin 4 receptor acts_upstream_of_or_within ISO (PMID:16424184) MGI PMID:16424184 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G IL6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) MGI PMID:12594267 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:26098997) UniProt PMID:26098997 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
G RARA retinoic acid receptor alpha involved_in ISO (PMID:18416830) BHF-UCL PMID:18416830 NCBI chr17:16,932,485...16,980,958 JBrowse link
G TNFSF4 TNF superfamily member 4 involved_in ISO (PMID:18354165) BHF-UCL PMID:18354165 NCBI chr 1:148,684,689...148,989,775
Ensembl chr 1:152,391,450...152,415,845
Ensembl chr 1:152,391,450...152,415,845 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SHB SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:37,768,566...37,921,897 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2521
      leukocyte activation 1005
        lymphocyte activation 816
          lymphocyte differentiation 434
            positive regulation of lymphocyte differentiation 120
              positive regulation of B cell differentiation + 18
              positive regulation of T cell differentiation + 103
              positive regulation of natural killer cell differentiation + 11
Path 2
Term Annotations click to browse term
  biological_process 19315
    developmental process 6685
      cellular developmental process 4499
        cell differentiation 4498
          cell development 3201
            hemopoiesis 1031
              leukocyte differentiation 665
                mononuclear cell differentiation 537
                  lymphocyte differentiation 434
                    regulation of lymphocyte differentiation 213
                      positive regulation of lymphocyte differentiation 120
                        positive regulation of B cell differentiation + 18
                        positive regulation of T cell differentiation + 103
                        positive regulation of natural killer cell differentiation + 11
paths to the root