ONTOLOGY REPORT - ANNOTATIONS
Term: positive regulation of lymphocyte differentiation
Accession: GO:0045621
browse the term
Definition: Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms: exact_synonym: up regulation of lymphocyte differentiation; upregulation of lymphocyte differentiation
narrow_synonym: activation of lymphocyte differentiation; stimulation of lymphocyte differentiation
related_synonym: positive regulation of lymphocyte development
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Inpp5d
inositol polyphosphate-5-phosphatase D
acts_upstream_of_or_within
ISO
MGI:2386884 (PMID:9620849)
RGD
PMID:9620849
NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
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Nckap1l
NCK associated protein 1 like
involved_in
ISS ISO
GO_REF:0000024 (PMID:19015308)
UniProt RGD
PMID:19015308
GO_REF:0000024
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Prkdc
protein kinase, DNA-activated, catalytic subunit
involved_in
ISO
(PMID:32103174)
RGD
PMID:32103174
NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
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Stat5a
signal transducer and activator of transcription 5A
acts_upstream_of_or_within
ISO
MGI:103035 (PMID:15294943)
RGD
PMID:15294943
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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Stat5b
signal transducer and activator of transcription 5B
acts_upstream_of_or_within
ISO
MGI:103036 (PMID:15294943)
RGD
PMID:15294943
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Xrcc6
X-ray repair cross complementing 6
involved_in
ISO
(PMID:32103174)
RGD
PMID:32103174
NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
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Ada
adenosine deaminase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857117 (PMID:11067867), (PMID:12163459), (PMID:16670300)
Ensembl RGD
PMID:11067867 PMID:12163459 PMID:16670300
GO_REF:0000107
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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Gli3
GLI family zinc finger 3
involved_in
ISO
(PMID:15855276)
RGD
PMID:15855276
NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
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Ihh
Indian hedgehog signaling molecule
involved_in
ISO
(PMID:19109233)
RGD
PMID:19109233
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
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Itpkb
inositol-trisphosphate 3-kinase B
acts_upstream_of_or_within
ISO
MGI:3039799 (PMID:15064401)
RGD
PMID:15064401
NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
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Nkap
NFKB activating protein
involved_in
ISO ISS
(PMID:19409814) GO_REF:0000024
RGD UniProt
PMID:19409814
GO_REF:0000024
NCBI chr X:116,373,031...116,392,677
Ensembl chr X:116,372,839...116,394,945
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Pnp
purine nucleoside phosphorylase
acts_upstream_of_or_within
ISO
(PMID:16964310)
RGD
PMID:16964310
NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986
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Rhoa
ras homolog family member A
involved_in
ISO
(PMID:25398325)
RGD
PMID:25398325
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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Shh
sonic hedgehog signaling molecule
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:14764698) GO_REF:0000024
Ensembl RGD UniProt
PMID:14764698
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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Syk
spleen associated tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:99613 (PMID:9275205)
Ensembl RGD
PMID:9275205
GO_REF:0000107
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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Zap70
zeta chain of T cell receptor associated protein kinase 70
acts_upstream_of_or_within
ISO
MGI:2677447|MGI:3526403|MGI:99515 (PMID:7630421), (PMID:9208839), (PMID:9275205)
RGD
PMID:7630421 PMID:9208839 PMID:9275205
NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
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Atp11c
ATPase phospholipid transporting 11C
involved_in
ISO
(PMID:21423173)
RGD
PMID:21423173
NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204
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Bad
BCL2-associated agonist of cell death
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3029528 (PMID:12431371)
Ensembl RGD
PMID:12431371
GO_REF:0000107
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Cd27
CD27 molecule
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
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Il2rg
interleukin 2 receptor subunit gamma
acts_upstream_of_or_within
ISO
MGI:2429736|MGI:5544783 (PMID:23918385), (PMID:9252128)
RGD
PMID:9252128 PMID:23918385
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Il7
interleukin 7
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:16797412)
Ensembl RGD
PMID:16797412
GO_REF:0000107
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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Inpp5d
inositol polyphosphate-5-phosphatase D
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000107 MGI:2386884 (PMID:10704460), (PMID:9620849) GO_REF:0000033
Ensembl RGD GO_Central
PMID:9620849 PMID:10704460
GO_REF:0000033 GO_REF:0000107
NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746
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Mmp14
matrix metallopeptidase 14
involved_in
ISS ISO
GO_REF:0000024 (PMID:21572390)
UniProt RGD
PMID:21572390
GO_REF:0000024
NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
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Nckap1l
NCK associated protein 1 like
involved_in
ISS ISO
GO_REF:0000024 (PMID:19015308)
UniProt RGD
PMID:19015308
GO_REF:0000024
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Pcid2
PCI domain containing 2
involved_in
ISO
(PMID:20870947)
RGD
PMID:20870947
NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712
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Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000107 MGI:3759678 (PMID:16129705) GO_REF:0000033
Ensembl RGD GO_Central
PMID:16129705
GO_REF:0000033 GO_REF:0000107
NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491
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Spi1
Spi-1 proto-oncogene
involved_in
ISO IEA ISS
(PMID:33951726) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:33951726
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
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Stat5a
signal transducer and activator of transcription 5A
acts_upstream_of_or_within
ISO
MGI:103035 (PMID:10979977)
RGD
PMID:10979977
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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Stat5b
signal transducer and activator of transcription 5B
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:103036 (PMID:10979977)
Ensembl RGD
PMID:10979977
GO_REF:0000107
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Syk
spleen associated tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857421|MGI:2384078 (PMID:7477352), (PMID:7477353) (PMID:18369315)
Ensembl RGD
PMID:7477352 PMID:7477353 PMID:18369315
GO_REF:0000107
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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Xbp1
X-box binding protein 1
involved_in
ISO ISS
(PMID:11460154) GO_REF:0000024
RGD UniProt
PMID:11460154
GO_REF:0000024
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Cd83
CD83 molecule
acts_upstream_of_or_within
ISO
MGI:3055293 (PMID:15322158)
RGD
PMID:15322158
NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083
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Foxp3
forkhead box P3
acts_upstream_of_or_within
ISO
(PMID:17028180)
RGD
PMID:17028180
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
G
Nckap1l
NCK associated protein 1 like
involved_in
ISS ISO
GO_REF:0000024 (PMID:19015308)
UniProt RGD
PMID:19015308
GO_REF:0000024
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Sash3
SAM and SH3 domain containing 3
acts_upstream_of_or_within
ISO
MGI:3716944 (PMID:16227612)
RGD
PMID:16227612
NCBI chr X:127,326,815...127,341,521
Ensembl chr X:127,326,859...127,341,519
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Socs1
suppressor of cytokine signaling 1
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:24880459) GO_REF:0000024
Ensembl RGD UniProt
PMID:24880459
GO_REF:0000024 GO_REF:0000107
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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Tnfsf4
TNF superfamily member 4
involved_in
ISO
(PMID:20639485)
RGD
PMID:20639485
NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
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Zbtb7b
zinc finger and BTB domain containing 7B
involved_in
ISO
(PMID:24880459)
RGD
PMID:24880459
NCBI chr 2:174,795,831...174,811,980
Ensembl chr 2:174,797,453...174,814,236
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Foxp3
forkhead box P3
acts_upstream_of_or_within
ISO
MGI:1857034|MGI:2654936|MGI:3696705 (PMID:12612578), (PMID:16275384), (PMID:16301745), (PMID:18573908)
RGD
PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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Gimap5
GTPase, IMAP family member 5
IMP
RGD
PMID:15778366
RGD:2303772
NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
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Il2rg
interleukin 2 receptor subunit gamma
acts_upstream_of_or_within
ISO
MGI:1857455 (PMID:16227984)
RGD
PMID:16227984
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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Klhl25
kelch-like family member 25
involved_in
ISO ISS
(PMID:34491895) GO_REF:0000024
RGD UniProt
PMID:34491895
GO_REF:0000024
NCBI chr 1:129,724,894...129,750,142
Ensembl chr 1:129,722,026...129,750,227
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RT1-Da
RT1 class II, locus Da
involved_in
ISO
(PMID:28467828)
RGD
PMID:28467828
NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
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RT1-Db1
RT1 class II, locus Db1
involved_in
ISO
(PMID:28467828)
RGD
PMID:28467828
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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Ifng
interferon gamma
involved_in
ISO
(PMID:20209097)
RGD
PMID:20209097
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Lgals9
galectin 9
involved_in
ISO
(PMID:20209097)
RGD
PMID:20209097
NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
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Cbfb
core-binding factor subunit beta
involved_in
ISO
(PMID:18258917)
RGD
PMID:18258917
NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751
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Lilrb4
leukocyte immunoglobulin like receptor B4
involved_in
ISO
(PMID:18420485)
RGD
PMID:18420485
NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
G
Nckap1l
NCK associated protein 1 like
involved_in
ISS ISO
GO_REF:0000024 (PMID:19015308)
UniProt RGD
PMID:19015308
GO_REF:0000024
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Runx1
RUNX family transcription factor 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:18258917)
UniProt RGD
PMID:18258917
GO_REF:0000024
NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
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Runx3
RUNX family transcription factor 3
involved_in
ISO
(PMID:18258917)
RGD
PMID:18258917
NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156
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Sart1
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
involved_in
ISO
(PMID:10209962)
RGD
PMID:10209962
NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136
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Tnfsf9
TNF superfamily member 9
involved_in
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:19187795
GO_REF:0000033, RGD:2317344
NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
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Gimap5
GTPase, IMAP family member 5
IMP
RGD
PMID:11859104
RGD:625608
NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086
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Lck
LCK proto-oncogene, Src family tyrosine kinase
acts_upstream_of_or_within
ISO
MGI:1857211 (PMID:7807014)
RGD
PMID:7807014
NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
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Lef1
lymphoid enhancer binding factor 1
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:23562159) GO_REF:0000107
UniProt RGD Ensembl
PMID:23562159
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
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Nckap1l
NCK associated protein 1 like
involved_in
ISS ISO
GO_REF:0000024 (PMID:19015308)
UniProt RGD
PMID:19015308
GO_REF:0000024
NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934
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Ptprc
protein tyrosine phosphatase, receptor type, C
acts_upstream_of_or_within
ISO
MGI:2181288 (PMID:7807014)
RGD
PMID:7807014
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
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Sox13
SRY-box transcription factor 13
involved_in
ISO
(PMID:23562159)
RGD
PMID:23562159
NCBI chr13:44,831,097...44,875,522
Ensembl chr13:44,831,085...44,875,762
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Sox4
SRY-box transcription factor 4
involved_in
ISO
(PMID:23562159)
RGD
PMID:23562159
NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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Stat5a
signal transducer and activator of transcription 5A
acts_upstream_of_or_within
ISO
MGI:103035 (PMID:15294943)
RGD
PMID:15294943
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
G
Stat5b
signal transducer and activator of transcription 5B
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:103036 (PMID:15294943)
Ensembl RGD
PMID:15294943
GO_REF:0000107
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
G
Syk
spleen associated tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857421|MGI:2384078 (PMID:7477352), (PMID:8790395)
Ensembl RGD
PMID:7477352 PMID:8790395
GO_REF:0000107
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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Cd46
CD46 molecule
involved_in
ISO
(PMID:12540904)
RGD
PMID:12540904
NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
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Il23a
interleukin 23 subunit alpha
involved_in
ISO
(PMID:14688363)
RGD
PMID:14688363
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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Pck1
phosphoenolpyruvate carboxykinase 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:29230018)
UniProt RGD
PMID:29230018
GO_REF:0000024
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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RT1-Da
RT1 class II, locus Da
involved_in
ISO
(PMID:27591323)
RGD
PMID:27591323
NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
G
RT1-Db1
RT1 class II, locus Db1
involved_in
ISO
(PMID:27591323)
RGD
PMID:27591323
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
G
Tnfsf4
TNF superfamily member 4
involved_in
ISO
(PMID:18713990)
RGD
PMID:18713990
NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
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Axl
Axl receptor tyrosine kinase
involved_in
ISO
(PMID:18840707)
RGD
PMID:18840707
NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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Flt3lg
Fms related receptor tyrosine kinase 3 ligand
acts_upstream_of_or_within
ISO
MGI:2158499 (PMID:14607906)
RGD
PMID:14607906
NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
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Gas6
growth arrest specific 6
involved_in
ISS ISO
GO_REF:0000024 (PMID:18840707)
UniProt RGD
PMID:18840707
GO_REF:0000024
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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Il15
interleukin 15
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1931086|MGI:2136897 (PMID:14607906), (PMID:17318811)
Ensembl RGD
PMID:14607906 PMID:17318811
GO_REF:0000107
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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Il15ra
interleukin 15 receptor subunit alpha
acts_upstream_of_or_within
ISO
MGI:1934016 (PMID:14607906)
RGD
PMID:14607906
NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
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Il21
interleukin 21
acts_upstream_of_or_within
ISO
(PMID:14764669)
RGD
PMID:14764669
NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
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Rasgrp1
RAS guanyl releasing protein 1
involved_in
IEA ISO
GO_REF:0000107 (PMID:21957144)
Ensembl RGD
PMID:21957144
GO_REF:0000107
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
G
Stat5a
signal transducer and activator of transcription 5A
acts_upstream_of_or_within
ISO
MGI:1857249 (PMID:9841920)
RGD
PMID:9841920
NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
G
Stat5b
signal transducer and activator of transcription 5B
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2181592 (PMID:9841920)
Ensembl RGD
PMID:9841920
GO_REF:0000107
NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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Tox
thymocyte selection-associated high mobility group box
acts_upstream_of_or_within
ISO
MGI:3773716 (PMID:20818394)
RGD
PMID:20818394
NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
G
Zbtb1
zinc finger and BTB domain containing 1
involved_in
ISO
(PMID:22753936)
RGD
PMID:22753936
NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
G
Ap3b1
adaptor related protein complex 3 subunit beta 1
acts_upstream_of_or_within
ISO
MGI:1856989 (PMID:14557411)
RGD
PMID:14557411
NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
G
Ap3d1
adaptor related protein complex 3 subunit delta 1
acts_upstream_of_or_within
ISO
MGI:1856083 (PMID:14557411)
RGD
PMID:14557411
NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643
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Cd1d1
CD1d1 molecule
acts_upstream_of_or_within
ISO
MGI:2180711|MGI:2180713 (PMID:10201995), (PMID:9133426)
RGD
PMID:9133426 PMID:10201995
NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
G
Tgfbr2
transforming growth factor, beta receptor 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2183502|MGI:2386448 (PMID:16973387)
Ensembl RGD
PMID:16973387
GO_REF:0000107
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
G
Ddrgk1
DDRGK domain containing 1
involved_in
IEA ISO
GO_REF:0000107 (PMID:30842412)
Ensembl RGD
PMID:30842412
GO_REF:0000107
NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
G
Il10
interleukin 10
acts_upstream_of
ISO
UniProtKB:P60568 (PMID:22962438)
RGD
PMID:22962438
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il2
interleukin 2
acts_upstream_of
ISO
UniProtKB:P22301 (PMID:22962438)
RGD
PMID:22962438
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Xbp1
X-box binding protein 1
involved_in
ISO IEA ISS
(PMID:11460154) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:11460154
GO_REF:0000024 GO_REF:0000107
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Zbtb1
zinc finger and BTB domain containing 1
involved_in
ISO
(PMID:22753936)
RGD
PMID:22753936
NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
G
Ambra1
autophagy and beclin 1 regulator 1
involved_in
ISO
(PMID:30513302)
RGD
PMID:30513302
NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221
G
Bcl6
BCL6, transcription repressor
involved_in
ISO
(PMID:20935202), (PMID:22387553)
RGD
PMID:20935202 PMID:22387553
NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
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Btn2a2
butyrophilin, subfamily 2, member A2
acts_upstream_of_or_within
ISO
(PMID:23589618)
RGD
PMID:23589618
NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
G
Carmil2
capping protein regulator and myosin 1 linker 2
acts_upstream_of_or_within
ISO
MGI:4462559|MGI:5547539 (PMID:23793062)
RGD
PMID:23793062
NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
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Cd46
CD46 molecule
involved_in
ISO
(PMID:12540904)
RGD
PMID:12540904
NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
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Dusp10
dual specificity phosphatase 10
involved_in
ISO
(PMID:22387553)
RGD
PMID:22387553
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Foxo3
forkhead box O3
involved_in
ISO
(PMID:30513302)
RGD
PMID:30513302
NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
G
Foxp3
forkhead box P3
involved_in acts_upstream_of_or_within
ISO
(PMID:30513302) MGI:2654936 (PMID:12522256), (PMID:15100250), (PMID:15780990), (PMID:16769892), (PMID:17028180)
RGD
PMID:12522256 PMID:15100250 PMID:15780990 PMID:16769892 PMID:17028180 PMID:30513302 More...
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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Il2
interleukin 2
IDA
RGD
PMID:6233372
RGD:1600097
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Il4i1
interleukin 4 induced 1
involved_in
ISO
(PMID:25778793)
RGD
PMID:25778793
NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562
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Kat5
lysine acetyltransferase 5
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:24835996) GO_REF:0000107
UniProt RGD Ensembl
PMID:24835996
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
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Lgals9
galectin 9
involved_in
ISO
(PMID:25065622)
RGD
PMID:25065622
NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
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Lilrb4
leukocyte immunoglobulin like receptor B4
involved_in
ISO
(PMID:20935202), (PMID:22387553)
RGD
PMID:20935202 PMID:22387553
NCBI chr 1:69,805,020...69,810,628
Ensembl chr 1:69,805,250...69,810,660
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Mir214
microRNA 214
IMP
RGD
PMID:30287503
RGD:38549580
NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
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RT1-M3-1
RT1 class Ib, locus M3, gene 1
involved_in
ISO
(PMID:20448110)
RGD
PMID:20448110
NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
G
Socs1
suppressor of cytokine signaling 1
involved_in
ISO IEA
(PMID:22387553) GO_REF:0000107
RGD Ensembl
PMID:22387553
GO_REF:0000107
NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
G
Sox12
SRY-box transcription factor 12
involved_in
ISO
(PMID:30190287)
RGD
PMID:30190287
NCBI chr 3:140,859,499...140,860,518
Ensembl chr 3:140,856,579...140,860,975
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Tgfb1
transforming growth factor, beta 1
involved_in
ISO
(PMID:25065622)
RGD
PMID:25065622
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Vsir
V-set immunoregulatory receptor
involved_in
ISO
(PMID:24691993)
RGD
PMID:24691993
NCBI chr20:28,281,582...28,307,262
Ensembl chr20:28,281,596...28,303,878
G
Ada
adenosine deaminase
acts_upstream_of_or_within
ISO
MGI:1857117|MGI:2683027 (PMID:7731963), (PMID:9478961)
RGD
PMID:7731963 PMID:9478961
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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Bad
BCL2-associated agonist of cell death
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3029528 (PMID:12431371)
Ensembl RGD
PMID:12431371
GO_REF:0000107
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Cd27
CD27 molecule
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
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Cd74
CD74 molecule
acts_upstream_of_or_within
ISO
MGI:1927205|MGI:1927530 (PMID:7679955), (PMID:8598040), (PMID:9432982)
RGD
PMID:7679955 PMID:8598040 PMID:9432982
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Cyld
CYLD lysine 63 deubiquitinase
acts_upstream_of_or_within
ISO
MGI:3664438 (PMID:16501569)
RGD
PMID:16501569
NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658
G
Gata3
GATA binding protein 3
involved_in
ISO
(PMID:20696860)
RGD
PMID:20696860
NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
G
Il12a
interleukin 12A
acts_upstream_of_or_within
ISO
MGI:1916927 (PMID:22968459)
RGD
PMID:22968459
NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
G
Il1rl2
interleukin 1 receptor-like 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:22968459)
Ensembl RGD
PMID:22968459
GO_REF:0000107
NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667
G
Il2
interleukin 2
IDA
RGD
PMID:9352365
RGD:1600138
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
G
Il2ra
interleukin 2 receptor subunit alpha
IMP
RGD
PMID:9352365
RGD:1600138
NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697
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Il36b
interleukin 36, beta
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 MGI:96539 (PMID:22968459)
GO_Central RGD
PMID:22968459
GO_REF:0000033
NCBI chr 3:7,024,881...7,030,388
Ensembl chr 3:7,021,973...7,031,619
G
Il4
interleukin 4
involved_in
ISO
(PMID:20554961)
RGD
PMID:20554961
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il7
interleukin 7
involved_in acts_upstream_of_or_within
IEA ISO ISS
GO_REF:0000107 (PMID:12431371) GO_REF:0000024
Ensembl RGD UniProt
PMID:12431371
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
G
Mdk
midkine
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:28183532) GO_REF:0000107
UniProt RGD Ensembl
PMID:28183532
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
G
Pik3r6
phosphoinositide-3-kinase, regulatory subunit 6
involved_in
ISO
(PMID:12707323)
RGD
PMID:12707323
NCBI chr10:53,203,930...53,255,229
Ensembl chr10:53,205,496...53,255,243
G
Ptprc
protein tyrosine phosphatase, receptor type, C
acts_upstream_of_or_within
ISO
MGI:1857277 (PMID:8666928)
RGD
PMID:8666928
NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
G
Rag1
recombination activating 1
involved_in
ISO
(PMID:1547488)
RGD
PMID:1547488
NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291
G
Rhoh
ras homolog family member H
involved_in
ISO
(PMID:22850876)
RGD
PMID:22850876
NCBI chr14:42,341,135...42,371,971
Ensembl chr14:42,337,751...42,386,369
G
RT1-Ba
RT1 class II, locus Ba
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:8598041)
Ensembl RGD
PMID:8598041
GO_REF:0000107
NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744
G
RT1-DMa
RT1 class II, locus DMa
acts_upstream_of_or_within
ISO
MGI:1861933|MGI:2384509|MGI:2652160 (PMID:8598040), (PMID:8598041), (PMID:8638109), (PMID:9432982)
RGD
PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982
NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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Wnt10b
Wnt family member 10B
acts_upstream_of_or_within
ISO
(PMID:19723499)
RGD
PMID:19723499
NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892
G
Xbp1
X-box binding protein 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:11460154)
UniProt Ensembl RGD
PMID:11460154
GO_REF:0000024 GO_REF:0000107
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
G
Zap70
zeta chain of T cell receptor associated protein kinase 70
acts_upstream_of_or_within
ISO
(PMID:7630421) MGI:2677447|MGI:3526403 (PMID:9208839)
RGD
PMID:7630421 PMID:9208839
NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700
G
Zbtb1
zinc finger and BTB domain containing 1
involved_in
ISO
(PMID:22201126)
RGD
PMID:22201126
NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
G
Zmiz1
zinc finger, MIZ-type containing 1
involved_in
ISO
(PMID:26522984)
RGD
PMID:26522984
NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
G
Ada
adenosine deaminase
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857117|MGI:2683027 (PMID:11067867), (PMID:11435465), (PMID:12163459), (PMID:16670300)
Ensembl RGD
PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300
GO_REF:0000107
NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
G
Adam8
ADAM metallopeptidase domain 8
involved_in
ISO
(PMID:20856819)
RGD
PMID:20856819
NCBI chr 1:194,776,559...194,789,330
Ensembl chr 1:194,770,060...194,788,801
G
Egr3
early growth response 3
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:21737317)
Ensembl RGD
PMID:21737317
GO_REF:0000107
NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
G
Ihh
Indian hedgehog signaling molecule
involved_in
ISO
(PMID:19109233)
RGD
PMID:19109233
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
G
Il2rg
interleukin 2 receptor subunit gamma
acts_upstream_of_or_within
ISO
MGI:1857455|MGI:2429736 (PMID:9252128), (PMID:9916699)
RGD
PMID:9252128 PMID:9916699
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
G
Il7r
interleukin 7 receptor
acts_upstream_of_or_within
ISO
MGI:1857198 (PMID:9215626)
RGD
PMID:9215626
NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
G
Rasgrp1
RAS guanyl releasing protein 1
involved_in
IEA ISO
GO_REF:0000107 (PMID:11017103)
Ensembl RGD
PMID:11017103
GO_REF:0000107
NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
G
Shh
sonic hedgehog signaling molecule
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:19109233) GO_REF:0000107
UniProt RGD Ensembl
PMID:19109233
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
G
Vnn1
vanin 1
involved_in
ISO
(PMID:8934567)
RGD
PMID:8934567
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
G
Anxa1
annexin A1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:17008549)
UniProt Ensembl RGD
PMID:17008549
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343
G
Ccl19
C-C motif chemokine ligand 19
involved_in
ISO
(PMID:15845453)
RGD
PMID:15845453
NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
G
Hlx
H2.0-like homeobox
acts_upstream_of_or_within
ISO
MGI:105367|MGI:2182089 (PMID:16424184)
RGD
PMID:16424184
NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
G
Ripk2
receptor-interacting serine-threonine kinase 2
acts_upstream_of_or_within
ISO
MGI:2446070 (PMID:11894097)
RGD
PMID:11894097
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
Socs5
suppressor of cytokine signaling 5
involved_in
ISO
(PMID:12242343)
RGD
PMID:12242343
NCBI chr 6:7,481,039...7,512,644
Ensembl chr 6:7,481,095...7,514,834
G
Malt1
MALT1 paracaspase
involved_in
ISO
(PMID:25282160)
RGD
PMID:25282160
NCBI chr18:58,942,282...58,996,318
Ensembl chr18:58,942,299...58,994,260
G
Mir326
microRNA 326
acts_upstream_of_or_within
ISO
(PMID:19838199)
RGD
PMID:19838199
NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
G
Nfkbid
NFKB inhibitor delta
involved_in
ISO
(PMID:25282160)
RGD
PMID:25282160
NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447
G
Nfkbiz
NFKB inhibitor zeta
involved_in
ISO
(PMID:25282160)
RGD
PMID:25282160
NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
G
Nlrp3
NLR family, pyrin domain containing 3
involved_in
ISO
(PMID:26098997)
RGD
PMID:26098997
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
G
Brd2
bromodomain containing 2
involved_in
ISS ISO
GO_REF:0000024 (PMID:28262505)
UniProt RGD
PMID:28262505
GO_REF:0000024
NCBI chr20:4,727,078...4,735,389
Ensembl chr20:4,728,151...4,735,388
G
Brd4
bromodomain containing 4
involved_in
ISO
(PMID:28262505)
RGD
PMID:28262505
NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539
G
Ep300
E1A binding protein p300
involved_in
ISO
(PMID:28262505)
RGD
PMID:28262505
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
G
Il23a
interleukin 23 subunit alpha
involved_in
IBA ISO
GO_REF:0000033 (PMID:19501566)
GO_Central RGD
PMID:19501566
GO_REF:0000033
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
G
Opa1
OPA1, mitochondrial dynamin like GTPase
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:36171294)
UniProt Ensembl RGD
PMID:36171294
GO_REF:0000024 GO_REF:0000107
NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
G
Il18
interleukin 18
involved_in
IEA ISO
GO_REF:0000107 (PMID:12829194)
Ensembl RGD
PMID:12829194
GO_REF:0000107
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il4r
interleukin 4 receptor
acts_upstream_of_or_within
ISO
MGI:96109 (PMID:16424184)
RGD
PMID:16424184
NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980
G
Il6
interleukin 6
acts_upstream_of_or_within
ISO
(PMID:12594267)
RGD
PMID:12594267
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Nlrp3
NLR family, pyrin domain containing 3
involved_in
ISO
(PMID:26098997)
RGD
PMID:26098997
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
G
Prkcz
protein kinase C, zeta
involved_in
ISS ISO
GO_REF:0000024 (PMID:15987782)
UniProt RGD
PMID:15987782
GO_REF:0000024
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
G
Rara
retinoic acid receptor, alpha
involved_in
ISO
(PMID:18416830)
RGD
PMID:18416830
NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
G
Tnfsf4
TNF superfamily member 4
involved_in
ISO
(PMID:18354165)
RGD
PMID:18354165
NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
G
Shb
SH2 domain containing adaptor protein B
acts_upstream_of_or_within
ISO
MGI:3721903 (PMID:24645804)
RGD
PMID:24645804
NCBI chr 5:59,678,066...59,785,443
Ensembl chr 5:59,678,216...59,785,538
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all