ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of lymphocyte differentiation
Accession: GO:0045620
browse the term
Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.
Comment: Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms: exact_synonym: down regulation of lymphocyte differentiation; downregulation of lymphocyte differentiation
narrow_synonym: inhibition of lymphocyte differentiation
related_synonym: negative regulation of lymphocyte development
G
Fbxo7
F-box protein 7
acts_upstream_of_or_within
IMP IGI
(PMID:21652635)
MGI
PMID:21652635
NCBI chr10:85,856,313...85,887,737
Ensembl chr10:85,857,836...85,887,737
G
Gli3
GLI-Kruppel family member GLI3
involved_in
IMP
(PMID:19667090)
BHF-UCL
PMID:19667090
NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611
G
Ihh
Indian hedgehog
involved_in
IMP
(PMID:19109233)
BHF-UCL
PMID:19109233
NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
G
Shh
sonic hedgehog
acts_upstream_of_or_within
IMP
(PMID:10981962)
MGI
PMID:10981962
NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
G
Flt3
FMS-like tyrosine kinase 3
acts_upstream_of_or_within
IDA
(PMID:16618805)
MGI
PMID:16618805
NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299
G
Hmgb3
high mobility group box 3
acts_upstream_of_or_within
IDA
(PMID:12714519)
MGI
PMID:12714519
NCBI chr X:70,599,523...70,604,261
Ensembl chr X:70,599,524...70,604,282
G
Id2
inhibitor of DNA binding 2
acts_upstream_of_or_within
IMP
(PMID:18523151)
MGI
PMID:18523151
NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
G
Sfrp1
secreted frizzled-related protein 1
involved_in
ISO IMP
(PMID:18941195)
GO_Central UniProt
PMID:18941195
GO_REF:0000119
NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648
G
Cbfb
core binding factor beta
involved_in
IMP
(PMID:18258917)
UniProt
PMID:18258917
NCBI chr 8:105,897,306...105,944,621
Ensembl chr 8:105,897,306...105,944,621
G
Hmgb1
high mobility group box 1
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr 5:148,983,512...148,989,867
Ensembl chr 5:148,983,512...149,121,299
G
Runx1
runt related transcription factor 1
involved_in
IDA
(PMID:18258917)
UniProt
PMID:18258917
NCBI chr16:92,398,354...92,622,962
Ensembl chr16:92,398,354...92,623,037
G
Runx3
runt related transcription factor 3
involved_in
IMP
(PMID:18258917)
UniProt
PMID:18258917
NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301
G
Slc4a2
solute carrier family 4 (anion exchanger), member 2
involved_in
IMP
(PMID:24515893)
UniProt
PMID:24515893
NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
G
Socs1
suppressor of cytokine signaling 1
involved_in
IMP
(PMID:24880459)
UniProt
PMID:24880459
NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
G
Zbtb7b
zinc finger and BTB domain containing 7B
involved_in
IMP
(PMID:22730529), (PMID:24880459)
UniProt
PMID:22730529 PMID:24880459
NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083
G
Lilrb4a
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707
G
Lilrb4b
leukocyte immunoglobulin-like receptor, subfamily B, member 4B
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr10:51,356,757...51,362,417
Ensembl chr10:51,356,728...51,362,799
G
Bmp4
bone morphogenetic protein 4
involved_in
ISS ISO
UniProt GO_Central
GO_REF:0000024 GO_REF:0000119
NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
G
Cdkn2a
cyclin dependent kinase inhibitor 2A
involved_in
IMP
(PMID:15964995)
HGNC-UCL
PMID:15964995
NCBI chr 4:89,192,710...89,212,856
Ensembl chr 4:89,192,708...89,212,890
G
Clec4g
C-type lectin domain family 4, member g
acts_upstream_of_or_within
IMP
(PMID:23487419)
MGI
PMID:23487419
NCBI chr 8:3,757,066...3,770,695
Ensembl chr 8:3,757,064...3,770,651
G
Erbb2
erb-b2 receptor tyrosine kinase 2
acts_upstream_of_or_within
IMP
(PMID:16230479)
MGI
PMID:16230479
NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
G
Ihh
Indian hedgehog
involved_in
IMP
(PMID:19109233)
BHF-UCL
PMID:19109233
NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
G
Tmem131l
transmembrane 131 like
involved_in
ISS ISO
UniProt GO_Central
GO_REF:0000024 GO_REF:0000119
NCBI chr 3:83,804,955...83,947,497
Ensembl chr 3:83,804,962...83,947,482
G
Fgl2
fibrinogen-like protein 2
acts_upstream_of_or_within
IMP
(PMID:29341118)
MGI
PMID:29341118
NCBI chr 5:21,577,671...21,583,384
Ensembl chr 5:21,577,640...21,583,372
G
Pglyrp1
peptidoglycan recognition protein 1
acts_upstream_of_or_within
IMP
(PMID:20709292)
MGI
PMID:20709292
NCBI chr 7:18,618,615...18,624,363
Ensembl chr 7:18,605,256...18,624,384
G
Pglyrp2
peptidoglycan recognition protein 2
acts_upstream_of_or_within
IMP
(PMID:20709292)
MGI
PMID:20709292
NCBI chr17:32,631,433...32,643,157
Ensembl chr17:32,631,433...32,643,141
G
Pglyrp3
peptidoglycan recognition protein 3
acts_upstream_of_or_within
IMP
(PMID:20709292)
MGI
PMID:20709292
NCBI chr 3:91,919,784...91,939,979
Ensembl chr 3:91,921,890...91,938,889
G
Pglyrp4
peptidoglycan recognition protein 4
acts_upstream_of_or_within
IMP
(PMID:20709292)
MGI
PMID:20709292
NCBI chr 3:90,634,008...90,648,824
Ensembl chr 3:90,634,213...90,648,824
G
Bcl6
B cell leukemia/lymphoma 6
acts_upstream_of_or_within
IMP
(PMID:15240705)
MGI
PMID:15240705
NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
G
Lilrb4a
leukocyte immunoglobulin-like receptor, subfamily B, member 4A
involved_in
IMP
(PMID:24935931)
UniProt
PMID:24935931
NCBI chr10:51,366,999...51,372,709
Ensembl chr10:51,367,052...51,372,707
G
Ptpn2
protein tyrosine phosphatase, non-receptor type 2
involved_in
IMP
(PMID:22080863)
UniProt
PMID:22080863
NCBI chr18:67,798,571...67,857,697
Ensembl chr18:67,798,581...67,857,665
G
Cd44
CD44 antigen
involved_in
IMP
(PMID:25065622)
UniProt
PMID:25065622
NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
G
Ctla4
cytotoxic T-lymphocyte-associated protein 4
involved_in
IBA ISO
GO_Central
GO_REF:0000033 GO_REF:0000119
NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991
G
Hspb1
heat shock protein 1
involved_in
ISO
RGD GO_Central
PMID:30287503
GO_REF:0000096 RGD:38549580
NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
G
Irf1
interferon regulatory factor 1
involved_in
IMP
(PMID:18641303)
UniProt
PMID:18641303
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
G
Lag3
lymphocyte-activation gene 3
involved_in
IMP
(PMID:15485628)
UniProt
PMID:15485628
NCBI chr 6:124,881,322...124,888,668
Ensembl chr 6:124,881,324...124,888,668
G
Mdk
midkine
involved_in
ISO ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000119
NCBI chr 2:91,760,149...91,762,348
Ensembl chr 2:91,760,150...91,762,642
G
Mir21a
microRNA 21a
involved_in
ISO
(PMID:22387553)
BHF-UCL
PMID:22387553
NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
G
Mir30b
microRNA 30b
involved_in
ISO
(PMID:22387553)
BHF-UCL
PMID:22387553
NCBI chr15:68,209,264...68,209,359
Ensembl chr15:68,209,264...68,209,359
G
Tnfsf4
tumor necrosis factor (ligand) superfamily, member 4
involved_in
IMP
(PMID:18713990)
BHF-UCL
PMID:18713990
NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981
G
Tug1
taurine upregulated gene 1
ISO
RGD
PMID:30287503
RGD:38549580
NCBI chr11:3,589,313...3,599,021
Ensembl chr11:3,589,785...3,599,673
G
Cd74
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
acts_upstream_of_or_within
IMP
(PMID:7679955)
MGI
PMID:7679955
NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
G
Dtx1
deltex 1, E3 ubiquitin ligase
acts_upstream_of_or_within
IDA
(PMID:12794108)
MGI
PMID:12794108
NCBI chr 5:120,818,268...120,850,879
Ensembl chr 5:120,818,267...120,849,992
G
Ifna2
interferon alpha 2
involved_in
ISO
(PMID:20554961)
UniProt
PMID:20554961
NCBI chr 4:88,601,444...88,602,016
Ensembl chr 4:88,601,118...88,602,149
G
Ifnb1
interferon beta 1, fibroblast
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr 4:88,440,253...88,441,083
Ensembl chr 4:88,440,262...88,441,011
G
Nrarp
Notch-regulated ankyrin repeat protein
acts_upstream_of_or_within
IDA
(PMID:12794108)
MGI
PMID:12794108
NCBI chr 2:25,070,770...25,073,351
Ensembl chr 2:25,070,770...25,073,351
G
Prdx2
peroxiredoxin 2
acts_upstream_of_or_within
IMP
(PMID:16290204)
MGI
PMID:16290204
NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463
G
Bmp4
bone morphogenetic protein 4
involved_in
ISO
GO_Central
GO_REF:0000119
NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
G
Foxj1
forkhead box J1
involved_in
IMP
(PMID:16339515)
BHF-UCL
PMID:16339515
NCBI chr11:116,221,530...116,226,331
Ensembl chr11:116,221,530...116,226,225
G
Ihh
Indian hedgehog
involved_in
IMP
(PMID:19109233)
BHF-UCL
PMID:19109233
NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
G
Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
acts_upstream_of_or_within
IDA
(PMID:11931770)
MGI
PMID:11931770
NCBI chr 7:30,121,156...30,128,173
Ensembl chr 7:30,121,157...30,128,171
G
Rag2
recombination activating gene 2
involved_in
ISO IEA
RGD Ensembl GO_Central
PMID:30206106
GO_REF:0000096 GO_REF:0000107 RGD:38508903
NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874
G
Shh
sonic hedgehog
acts_upstream_of_or_within
IMP
(PMID:10981962)
MGI
PMID:10981962
NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254
G
Zc3h8
zinc finger CCCH type containing 8
involved_in
ISS ISO
UniProt GO_Central
GO_REF:0000024 GO_REF:0000119
NCBI chr 2:128,768,188...128,786,018
Ensembl chr 2:128,768,188...128,785,997
G
Zfp608
zinc finger protein 608
involved_in
TAS
(PMID:23076336)
UniProt
PMID:23076336
NCBI chr18:55,021,117...55,125,690
Ensembl chr18:55,021,120...55,125,627
G
Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
IMP
(PMID:24463518)
UniProt
PMID:24463518
NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001
G
Il4ra
interleukin 4 receptor, alpha
acts_upstream_of_or_within
IGI
(PMID:16424184)
MGI
PMID:16424184
NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646
G
Jak3
Janus kinase 3
involved_in
IMP
(PMID:16020505)
BHF-UCL
PMID:16020505
NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
G
Tnfsf4
tumor necrosis factor (ligand) superfamily, member 4
involved_in
IDA
(PMID:9670042)
BHF-UCL
PMID:9670042
NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981
G
Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
IMP
(PMID:24463518)
UniProt
PMID:24463518
NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001
G
Foxp3
forkhead box P3
involved_in
ISO ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000119
NCBI chr X:7,445,915...7,461,482
Ensembl chr X:7,439,883...7,461,484
G
Il2
interleukin 2
involved_in
IGI
(PMID:25642768)
BHF-UCL
PMID:25642768
NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
G
Il4
interleukin 4
acts_upstream_of_or_within
IDA
(PMID:18792410)
MGI
PMID:18792410
NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
G
Pf4
platelet factor 4
involved_in
ISO IEA
RGD GO_Central Ensembl
PMID:24986443
GO_REF:0000096 GO_REF:0000107 RGD:329901907
NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242
G
Rc3h1
RING CCCH (C3H) domains 1
involved_in
IMP
(PMID:25282160)
UniProt
PMID:25282160
NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548
G
Rc3h2
ring finger and CCCH-type zinc finger domains 2
involved_in
IMP
(PMID:25282160)
UniProt
PMID:25282160
NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915
G
Smad7
SMAD family member 7
involved_in
IMP
(PMID:25642768)
BHF-UCL
PMID:25642768
NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006
G
Tbx21
T-box 21
involved_in
IDA
(PMID:21151104)
UniProt
PMID:21151104
NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
G
Zbtb7b
zinc finger and BTB domain containing 7B
acts_upstream_of_or_within
IMP
(PMID:23034280)
MGI
PMID:23034280
NCBI chr 3:89,284,953...89,300,976
Ensembl chr 3:89,284,951...89,302,083
G
Zc3h12a
zinc finger CCCH type containing 12A
involved_in
IMP
(PMID:25282160)
UniProt
PMID:25282160
NCBI chr 4:125,012,207...125,021,674
Ensembl chr 4:125,012,216...125,021,633
G
Cd69
CD69 antigen
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:129,244,287...129,252,332
Ensembl chr 6:129,244,288...129,252,399
G
Jak3
Janus kinase 3
involved_in
ISO
(PMID:20696842)
UniProt
PMID:20696842
NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
G
Lgals1
lectin, galactose binding, soluble 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
G
Loxl3
lysyl oxidase-like 3
involved_in
IMP ISO
(PMID:28065600)
UniProt GO_Central
PMID:28065600
GO_REF:0000119
NCBI chr 6:83,011,186...83,029,547
Ensembl chr 6:83,011,154...83,029,543
G
Stat5a
signal transducer and activator of transcription 5A
involved_in
ISO
(PMID:20696842)
UniProt
PMID:20696842
NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
G
Tbx21
T-box 21
involved_in
IMP
(PMID:21151104)
UniProt
PMID:21151104
NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157
G
Tnfsf18
tumor necrosis factor (ligand) superfamily, member 18
involved_in
IMP
(PMID:24107315)
UniProt
PMID:24107315
NCBI chr 1:161,322,221...161,333,903
Ensembl chr 1:161,322,224...161,332,859
G
Anxa1
annexin A1
involved_in
ISO ISS
GO_Central UniProt
GO_REF:0000024 GO_REF:0000119
NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308
G
Ascl2
achaete-scute family bHLH transcription factor 2
involved_in
IMP
(PMID:24463518)
UniProt
PMID:24463518
NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001
G
Bcl6
B cell leukemia/lymphoma 6
acts_upstream_of_or_within
IGI
(PMID:12594267)
MGI
PMID:12594267
NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602
G
Hlx
H2.0-like homeobox
acts_upstream_of_or_within
IMP IGI
(PMID:16424184)
MGI
PMID:16424184
NCBI chr 1:184,459,340...184,464,690
Ensembl chr 1:184,459,337...184,464,816
G
Irf1
interferon regulatory factor 1
involved_in
TAS
(PMID:11244049)
UniProt
PMID:11244049
NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
G
Socs5
suppressor of cytokine signaling 5
involved_in
IDA
(PMID:12242343)
UniProt
PMID:12242343
NCBI chr17:87,414,707...87,445,153
Ensembl chr17:87,415,107...87,445,267
G
Zfp35
zinc finger protein 35
acts_upstream_of_or_within
IMP
(PMID:19783676)
MGI
PMID:19783676
NCBI chr18:24,122,134...24,138,428
Ensembl chr18:24,122,689...24,138,433
G
Rc3h1
RING CCCH (C3H) domains 1
acts_upstream_of_or_within
IMP
(PMID:15917799)
MGI
PMID:15917799
NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all