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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of regulatory T cell differentiation
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Accession:GO:0045590 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of regulatory T cell differentiation;   downregulation of regulatory T cell differentiation;   negative regulation of regulatory T lymphocyte differentiation;   negative regulation of suppressor T cell differentiation
 narrow_synonym: inhibition of regulatory T cell differentiation
 related_synonym: negative regulation of regulatory T cell development



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negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IBA
(PMID:18641304)
GO_REF:0000033
RGD
GO_Central
PMID:18641304 GO_REF:0000033 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:18641303)
UniProt
RGD
PMID:18641303 GO_REF:0000024 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
ISO
GO_REF:0000024
(PMID:15485628)
UniProt
RGD
PMID:15485628 GO_REF:0000024 NCBI chr 4:159,398,930...159,407,001
Ensembl chr 4:157,712,667...157,720,404
JBrowse link
G Mdk midkine involved_in ISO
ISS
IEA
(PMID:22323540)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:22323540 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS0000338542_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:102,021,543...102,021,629
Ensembl chr 7:100,132,589...100,132,675
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:18713990) RGD PMID:18713990 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:82,743,501...82,750,534
Ensembl chr14:78,522,506...78,526,927
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    immune system process 3120
      leukocyte activation 1075
        lymphocyte activation 869
          lymphocyte differentiation 449
            T cell differentiation 335
              regulatory T cell differentiation 49
                negative regulation of regulatory T cell differentiation 10
                  negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20553
    cellular process 19543
      cellular developmental process 4831
        cell differentiation 4830
          cell development 3338
            hemopoiesis 1083
              leukocyte differentiation 688
                mononuclear cell differentiation 552
                  lymphocyte differentiation 449
                    T cell differentiation 335
                      regulation of T cell differentiation 182
                        negative regulation of T cell differentiation 60
                          negative regulation of regulatory T cell differentiation 10
                            negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation + 0
paths to the root