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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of T cell differentiation
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Accession:GO:0045582 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of T cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: positive regulation of T lymphocyte differentiation;   up regulation of T cell differentiation;   upregulation of T cell differentiation
 narrow_synonym: activation of T cell differentiation;   stimulation of T cell differentiation
 related_synonym: positive regulation of T cell development


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positive regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:7731963), (PMID:9478961) 		Ensembl
RGD		 PMID:7731963 PMID:9478961 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:3029528 (PMID:12431371) RGD PMID:12431371 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:213,562,187...213,572,034 		JBrowse link
G Cd27 CD27 molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:159,716,935...159,721,823 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205|MGI:1927530 (PMID:7679955), (PMID:8598040), (PMID:9432982) RGD PMID:7679955 PMID:8598040 PMID:9432982 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:56,527,132...56,536,410 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3664438 (PMID:16501569) 		Ensembl
RGD		 PMID:16501569 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:34,488,583...34,547,118 		JBrowse link
G Gata3 GATA binding protein 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20696860) 		Ensembl
RGD		 PMID:20696860 GO_REF:0000107 NCBI chr17:73,544,234...73,575,670
Ensembl chr17:73,553,548...73,575,670 		JBrowse link
G Il12a interleukin 12A acts_upstream_of_or_within ISO MGI:1916927 (PMID:22968459) RGD PMID:22968459 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:155,275,625...155,282,997 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 acts_upstream_of_or_within ISO (PMID:22968459) RGD PMID:22968459 NCBI chr 9:50,087,271...50,134,225
Ensembl chr 9:50,083,903...50,204,607 		JBrowse link
G Il2 interleukin 2 IDA RGD PMID:9352365 RGD:1600138 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha IMP RGD PMID:9352365 RGD:1600138 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:71,759,802...71,808,507 		JBrowse link
G Il36b interleukin 36, beta acts_upstream_of_or_within ISO MGI:96539 (PMID:22968459) RGD PMID:22968459 NCBI chr 3:27,422,980...27,521,344
Ensembl chr 3:27,423,171...27,428,678 		JBrowse link
G Il4 interleukin 4 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:38,272,003...38,277,549 		JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
(PMID:12431371) 		UniProt
RGD		 PMID:12431371 GO_REF:0000024 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:96,142,092...96,187,389 		JBrowse link
G Mdk midkine involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28183532)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28183532 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:98,356,789...98,358,743 		JBrowse link
G Pik3r6 phosphoinositide-3-kinase, regulatory subunit 6 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12707323) 		Ensembl
RGD		 PMID:12707323 GO_REF:0000107 NCBI chr10:53,702,821...53,754,113
Ensembl chr10:53,704,682...53,754,497 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Rag1 recombination activating 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:1547488) 		Ensembl
RGD		 PMID:1547488 GO_REF:0000107 NCBI chr 3:108,372,087...108,383,184
Ensembl chr 3:108,371,978...108,383,261 		JBrowse link
G Rhoh ras homolog family member H involved_in ISO
IEA 		(PMID:22850876)
GO_REF:0000107 		RGD
Ensembl		 PMID:22850876 GO_REF:0000107 NCBI chr14:42,694,860...42,725,690
Ensembl chr14:42,693,413...42,749,967 		JBrowse link
G RT1-Ba RT1 class II, locus Ba acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:8598041) 		Ensembl
RGD		 PMID:8598041 GO_REF:0000107 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,576,843...4,581,653 		JBrowse link
G RT1-DMa RT1 class II, locus DMa acts_upstream_of_or_within ISO MGI:1861933|MGI:2384509|MGI:2652160 (PMID:8598040), (PMID:8598041), (PMID:8638109), (PMID:9432982) RGD PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chr20:4,708,932...4,712,335
Ensembl chr20:4,708,933...4,712,335 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 7:131,801,046...131,806,850
Ensembl chr 7:131,801,046...131,806,850 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:11460154) 		UniProt
Ensembl
RGD		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:84,604,107...84,609,706 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:7630421)
MGI:2677447|MGI:3526403 (PMID:9208839)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:7630421 PMID:9208839 GO_REF:0000107 GO_REF:0000117 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:46,485,598...46,509,062 		JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22201126) 		Ensembl
RGD		 PMID:22201126 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:100,838,714...100,852,643 		JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26522984) 		Ensembl
RGD		 PMID:26522984 GO_REF:0000107 NCBI chr16:1,033,983...1,239,425
Ensembl chr16:1,034,020...1,239,406 		JBrowse link
positive regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857117 (PMID:11067867), (PMID:12163459), (PMID:16670300) 		Ensembl
RGD		 PMID:11067867 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:15855276) 		Ensembl
RGD		 PMID:15855276 GO_REF:0000107 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:54,134,064...54,405,198 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA
ISO 		GO_REF:0000107
(PMID:19109233) 		Ensembl
RGD		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3039799 (PMID:15064401) 		Ensembl
RGD		 PMID:15064401 GO_REF:0000107 NCBI chr13:94,601,072...94,696,180
Ensembl chr13:94,601,167...94,696,179 		JBrowse link
G Nkap NFKB activating protein involved_in ISO
ISS 		(PMID:19409814)
GO_REF:0000024 		RGD
UniProt		 PMID:19409814 GO_REF:0000024 NCBI chr  X:121,238,714...121,258,360
Ensembl chr  X:121,238,404...121,261,238 		JBrowse link
G Pnp purine nucleoside phosphorylase acts_upstream_of_or_within ISO (PMID:16964310) RGD PMID:16964310 NCBI chr15:26,644,147...26,651,808
Ensembl chr15:26,643,858...26,678,162 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO (PMID:25398325) RGD PMID:25398325 NCBI chr 8:117,870,548...117,904,303
Ensembl chr 8:117,870,270...117,904,302 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS 		GO_REF:0000107
(PMID:14764698)
GO_REF:0000024 		Ensembl
RGD
UniProt		 PMID:14764698 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:99613 (PMID:9275205) 		Ensembl
RGD		 PMID:9275205 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278 		JBrowse link
G Zap70 zeta chain of T cell receptor associated protein kinase 70 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3526403|MGI:99515 (PMID:9208839), (PMID:9275205)
MGI:2677447 (PMID:7630421) 		Ensembl
RGD		 PMID:7630421 PMID:9208839 PMID:9275205 GO_REF:0000107 NCBI chr 9:46,485,605...46,507,552
Ensembl chr 9:46,485,598...46,509,062 		JBrowse link
positive regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd83 CD83 molecule acts_upstream_of_or_within ISO MGI:3055293 (PMID:15322158) RGD PMID:15322158 NCBI chr17:21,093,281...21,113,223
Ensembl chr17:21,093,281...21,113,047 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO 		GO_REF:0000024
(PMID:19015308) 		UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3716944 (PMID:16227612) 		Ensembl
RGD		 PMID:16227612 GO_REF:0000107 NCBI chr  X:132,204,717...132,219,421
Ensembl chr  X:132,204,543...132,219,419 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:24880459) 		UniProt
RGD		 PMID:24880459 GO_REF:0000024 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20639485) 		Ensembl
RGD		 PMID:20639485 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in IEA
ISO 		GO_REF:0000107
(PMID:24880459) 		Ensembl
RGD		 PMID:24880459 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:177,095,185...177,109,031 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxp3 forkhead box P3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857034|MGI:2654936|MGI:3696705 (PMID:12612578), (PMID:16275384), (PMID:16301745), (PMID:18573908) 		Ensembl
RGD		 PMID:12612578 PMID:16275384 PMID:16301745 PMID:18573908 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:15778366 RGD:2303772 NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:79,024,304...79,039,030 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857455 (PMID:16227984) 		Ensembl
RGD		 PMID:16227984 GO_REF:0000107 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Klhl25 kelch-like family member 25 involved_in ISO
IEA
ISS 		(PMID:34491895)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:34491895 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:139,134,655...139,159,898
Ensembl chr 1:139,122,977...139,165,970 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA 		(PMID:28467828)
GO_REF:0000107 		RGD
Ensembl		 PMID:28467828 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:28467828) RGD PMID:28467828 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:55,761,736...55,793,216 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:20209097) RGD PMID:20209097 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
positive regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in IEA
ISO 		GO_REF:0000107
(PMID:18258917) 		Ensembl
RGD		 PMID:18258917 GO_REF:0000107 NCBI chr19:49,955,133...50,002,661
Ensembl chr19:49,959,096...50,002,657 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:18420485) RGD PMID:18420485 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO 		GO_REF:0000024
(PMID:19015308) 		UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:18258917) 		UniProt
RGD		 PMID:18258917 GO_REF:0000024 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:45,329,044...45,564,925 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) RGD PMID:18258917 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:152,644,270...152,702,835 		JBrowse link
positive regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP involved_in ISO
IEA 		(PMID:10209962)
GO_REF:0000107 		RGD
Ensembl		 PMID:10209962 GO_REF:0000107 NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:212,104,557...212,128,486 		JBrowse link
G Tnfsf9 TNF superfamily member 9 involved_in IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:19187795 GO_REF:0000033, RGD:2317344 NCBI chr 9:2,031,011...2,033,345
Ensembl chr 9:2,030,953...2,033,339 		JBrowse link
positive regulation of gamma-delta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:11859104 RGD:625608 NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:79,024,304...79,039,030 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase acts_upstream_of_or_within ISO MGI:1857211 (PMID:7807014) RGD PMID:7807014 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:147,172,642...147,201,267 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:23562159)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:23562159 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:222,340,704...222,453,929 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO 		GO_REF:0000024
(PMID:19015308) 		UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:136,455,897...136,501,384 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:7807014) RGD PMID:7807014 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:52,147,717...52,259,746 		JBrowse link
G Sox13 SRY-box transcription factor 13 involved_in IEA
ISO 		GO_REF:0000107
(PMID:23562159) 		Ensembl
RGD		 PMID:23562159 GO_REF:0000107 NCBI chr13:47,383,145...47,427,572
Ensembl chr13:47,383,145...47,435,663 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:23562159) RGD PMID:23562159 NCBI chr17:35,876,298...35,881,004
Ensembl chr17:35,875,756...35,884,024 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103035 (PMID:15294943) 		Ensembl
RGD		 PMID:15294943 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:86,285,547...86,310,184 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:103036 (PMID:15294943) 		Ensembl
RGD		 PMID:15294943 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:86,207,293...86,275,990 		JBrowse link
G Syk spleen associated tyrosine kinase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857421|MGI:2384078 (PMID:7477352), (PMID:8790395) 		Ensembl
RGD		 PMID:7477352 PMID:8790395 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,756,493...12,813,278 		JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IEA
ISO 		GO_REF:0000107
(PMID:14688363) 		Ensembl
RGD		 PMID:14688363 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:29230018)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:29230018 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:182,348,572...182,354,561 		JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO
IEA 		(PMID:27591323)
GO_REF:0000107 		RGD
Ensembl		 PMID:27591323 GO_REF:0000107 NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,513,908...4,520,383 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,550,596...4,560,165 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18713990) 		Ensembl
RGD		 PMID:18713990 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of NK T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO MGI:1856989 (PMID:14557411) RGD PMID:14557411 NCBI chr 2:27,331,241...27,535,683
Ensembl chr 2:27,334,900...27,537,702 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1856083 (PMID:14557411) 		Ensembl
RGD		 PMID:14557411 GO_REF:0000107 NCBI chr 7:9,620,909...9,656,350
Ensembl chr 7:9,620,968...9,656,342 		JBrowse link
G Cd1d1 CD1d1 molecule acts_upstream_of_or_within ISO MGI:2180711|MGI:2180713 (PMID:10201995), (PMID:9133426) RGD PMID:9133426 PMID:10201995 NCBI chr 2:174,721,522...174,725,029
Ensembl chr 2:174,721,522...174,725,029 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158690|MGI:2158738 (PMID:10366784) RGD PMID:10366784 NCBI chr14:90,468,696...90,556,522
Ensembl chr14:90,469,172...90,557,574 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2183502|MGI:2386448 (PMID:16973387) 		Ensembl
RGD		 PMID:16973387 GO_REF:0000107 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:124,674,986...124,761,469 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18660811) 		Ensembl
RGD		 PMID:18660811 GO_REF:0000107 NCBI chr 8:57,885,886...58,073,507
Ensembl chr 8:57,891,081...58,073,507 		JBrowse link
positive regulation of pro-T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb1 zinc finger and BTB domain containing 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:22753936) 		Ensembl
RGD		 PMID:22753936 GO_REF:0000107 NCBI chr 6:100,832,506...100,864,019
Ensembl chr 6:100,838,714...100,852,643 		JBrowse link
positive regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ambra1 autophagy and beclin 1 regulator 1 involved_in ISO
IEA 		(PMID:30513302)
GO_REF:0000117
GO_REF:0000107 		RGD
UniProt
Ensembl		 PMID:30513302 GO_REF:0000107 GO_REF:0000117 NCBI chr 3:98,156,626...98,345,876
Ensembl chr 3:98,156,652...98,345,872 		JBrowse link
G Bcl6 BCL6, transcription repressor involved_in ISO
IEA 		(PMID:20935202), (PMID:22387553)
GO_REF:0000107 		RGD
Ensembl		 PMID:20935202 PMID:22387553 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:90,358,753...90,382,047 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:23589618) 		Ensembl
RGD		 PMID:23589618 GO_REF:0000107 NCBI chr17:42,048,842...42,060,650
Ensembl chr17:42,048,842...42,060,650 		JBrowse link
G Carmil2 capping protein regulator and myosin 1 linker 2 acts_upstream_of_or_within ISO MGI:4462559|MGI:5547539 (PMID:23793062) RGD PMID:23793062 NCBI chr19:50,481,911...50,496,672
Ensembl chr19:50,484,324...50,496,669 		JBrowse link
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:109,104,122...109,134,903 JBrowse link
G Dusp10 dual specificity phosphatase 10 involved_in ISO
IEA 		(PMID:22387553)
GO_REF:0000107 		RGD
Ensembl		 PMID:22387553 GO_REF:0000107 NCBI chr13:98,145,317...98,183,304
Ensembl chr13:98,145,893...98,183,304 		JBrowse link
G Foxo3 forkhead box O3 involved_in ISO
IEA 		(PMID:30513302)
GO_REF:0000107 		RGD
Ensembl		 PMID:30513302 GO_REF:0000107 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:47,255,878...47,346,845 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:30513302)
MGI:2654936 (PMID:12522256), (PMID:15100250), (PMID:15780990), (PMID:16769892), (PMID:17028180)
GO_REF:0000107 		RGD
Ensembl		 PMID:12522256 PMID:15100250 PMID:15780990 PMID:16769892 PMID:17028180 More... GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:17,580,380...17,595,894 		JBrowse link
G Il2 interleukin 2 IDA RGD PMID:6233372 RGD:1600097 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:121,932,968...121,937,672 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:25778793) RGD PMID:25778793 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:104,435,981...104,461,053 		JBrowse link
G Kat5 lysine acetyltransferase 5 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:24835996)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:24835996 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:212,325,089...212,332,640
Ensembl chr 1:212,325,090...212,332,587 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:64,405,044...64,428,070 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:20935202), (PMID:22387553) RGD PMID:20935202 PMID:22387553 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:78,847,685...78,853,326 		JBrowse link
G Mir214 microRNA 214 IMP RGD PMID:30287503 RGD:38549580 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:77,121,643...77,121,752 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:20448110) RGD PMID:20448110 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,329,225...1,333,366 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISO
IEA 		(PMID:22387553)
GO_REF:0000107 		RGD
Ensembl		 PMID:22387553 GO_REF:0000107 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:5,389,334...5,391,847 		JBrowse link
G Sox12 SRY-box transcription factor 12 involved_in ISO (PMID:30190287) RGD PMID:30190287 NCBI chr 3:161,319,800...161,320,819
Ensembl chr 3:161,298,764...161,326,428 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:25065622) 		Ensembl
RGD		 PMID:25065622 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,823,945...28,850,175 		JBrowse link
positive regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:11067867), (PMID:11435465), (PMID:12163459), (PMID:16670300) 		Ensembl
RGD		 PMID:11067867 PMID:11435465 PMID:12163459 PMID:16670300 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:172,818,176...172,842,293 		JBrowse link
G Adam8 ADAM metallopeptidase domain 8 involved_in IEA
ISO 		GO_REF:0000107
(PMID:20856819) 		Ensembl
RGD		 PMID:20856819 GO_REF:0000107 NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:204,206,199...204,218,485 		JBrowse link
G Egr3 early growth response 3 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
(PMID:21737317) 		Ensembl
RGD		 PMID:21737317 GO_REF:0000107 NCBI chr15:51,560,482...51,565,778
Ensembl chr15:51,560,344...51,565,712 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in IEA
ISO 		GO_REF:0000107
(PMID:19109233) 		Ensembl
RGD		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:83,952,986...83,959,203 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857455|MGI:2429736 (PMID:9252128), (PMID:9916699) 		Ensembl
RGD		 PMID:9252128 PMID:9916699 GO_REF:0000107 NCBI chr  X:70,435,340...70,439,052
Ensembl chr  X:70,435,343...70,439,161 		JBrowse link
G Il7r interleukin 7 receptor acts_upstream_of_or_within ISO MGI:1857198 (PMID:9215626) RGD PMID:9215626 NCBI chr 2:60,179,561...60,204,937
Ensembl chr 2:60,181,382...60,211,027 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:11017103) 		Ensembl
RGD		 PMID:11017103 GO_REF:0000107 NCBI chr 3:124,624,039...124,684,079
Ensembl chr 3:124,622,313...124,684,434 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:19109233)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:19109233 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:7,687,846...7,697,901 		JBrowse link
G Vnn1 vanin 1 involved_in IEA
ISO 		GO_REF:0000107
(PMID:8934567) 		Ensembl
RGD		 PMID:8934567 GO_REF:0000107 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:23,356,330...23,366,629 		JBrowse link
positive regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:17008549) 		UniProt
Ensembl
RGD		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:227,287,717...227,306,831 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:15845453) RGD PMID:15845453 NCBI chr 5:61,759,220...61,761,164
Ensembl chr 5:61,759,220...61,772,022 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:105367|MGI:2182089 (PMID:16424184) 		Ensembl
RGD		 PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:98,811,856...98,817,264 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2446070 (PMID:11894097) 		Ensembl
RGD		 PMID:11894097 GO_REF:0000107 NCBI chr 5:34,428,573...34,459,808
Ensembl chr 5:34,428,573...34,459,663 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:13,234,062...13,273,883 		JBrowse link
positive regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Malt1 MALT1 paracaspase involved_in IEA
ISO 		GO_REF:0000107
(PMID:25282160) 		Ensembl
RGD		 PMID:25282160 GO_REF:0000107 NCBI chr18:61,212,290...61,266,272
Ensembl chr18:61,212,317...61,266,272 		JBrowse link
G Mir326 microRNA 326 acts_upstream_of_or_within ISO (PMID:19838199) RGD PMID:19838199 NCBI chr 1:163,266,165...163,266,259
Ensembl chr 1:163,266,165...163,266,259 		JBrowse link
G Nfkbid NFKB inhibitor delta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:94,808,453...94,817,861 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:58,251,721...58,279,767 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26098997) 		Ensembl
RGD		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
positive regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd2 bromodomain containing 2 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:28262505)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:28262505 GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,728,282...4,737,286
Ensembl chr20:4,728,951...4,737,290 		JBrowse link
G Brd4 bromodomain containing 4 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:11,866,997...11,946,575
Ensembl chr 7:11,866,997...11,946,923 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:28262505) RGD PMID:28262505 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574 		JBrowse link
G Il23a interleukin 23 subunit alpha involved_in IBA
IEA
ISO 		GO_REF:0000033
GO_REF:0000107
(PMID:19501566) 		GO_Central
Ensembl
RGD		 PMID:19501566 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:1,306,320...1,308,434
Ensembl chr 7:1,306,320...1,308,434 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:36171294) 		UniProt
Ensembl
RGD		 PMID:36171294 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:84,615,340...84,689,955 		JBrowse link
positive regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il18 interleukin 18 involved_in IEA
ISO 		GO_REF:0000107
(PMID:12829194) 		Ensembl
RGD		 PMID:12829194 GO_REF:0000107 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:59,809,592...59,831,286 		JBrowse link
G Il6 interleukin 6 acts_upstream_of_or_within ISO (PMID:12594267) RGD PMID:12594267 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 involved_in IEA
ISO 		GO_REF:0000107
(PMID:26098997) 		Ensembl
RGD		 PMID:26098997 GO_REF:0000107 NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,828,014...44,853,394 		JBrowse link
G Prkcz protein kinase C, zeta involved_in ISS
ISO 		GO_REF:0000024
(PMID:15987782) 		UniProt
RGD		 PMID:15987782 GO_REF:0000024 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:171,101,774...171,212,674 		JBrowse link
G Rara retinoic acid receptor, alpha involved_in ISO
IEA 		(PMID:18416830)
GO_REF:0000107 		RGD
Ensembl		 PMID:18416830 GO_REF:0000107 NCBI chr10:84,379,780...84,424,371
Ensembl chr10:84,389,622...84,425,160 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in IEA
ISO 		GO_REF:0000107
(PMID:18354165) 		Ensembl
RGD		 PMID:18354165 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:76,256,654...76,280,133 		JBrowse link
positive regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:35668320) RGD PMID:35668320 NCBI chr 6:123,245,534...123,262,758
Ensembl chr 6:123,219,633...123,266,285 		JBrowse link
G Shb SH2 domain containing adaptor protein B acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:3721903 (PMID:24645804) 		Ensembl
RGD		 PMID:24645804 GO_REF:0000107 NCBI chr 5:64,473,694...64,581,072
Ensembl chr 5:64,473,694...64,581,072 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2920
      leukocyte activation 1068
        lymphocyte activation 867
          lymphocyte differentiation 454
            T cell differentiation 337
              positive regulation of T cell differentiation 106
                positive regulation of T cell differentiation in thymus + 9
                positive regulation of alpha-beta T cell differentiation + 55
                positive regulation of cytotoxic T cell differentiation 2
                positive regulation of extrathymic T cell differentiation 0
                positive regulation of gamma-delta T cell differentiation 10
                positive regulation of memory T cell differentiation 6
                positive regulation of pro-T cell differentiation 1
                positive regulation of regulatory T cell differentiation + 25
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18484
      cellular developmental process 4933
        cell differentiation 4932
          cell development 3418
            hemopoiesis 1096
              leukocyte differentiation 699
                mononuclear cell differentiation 559
                  lymphocyte differentiation 454
                    T cell differentiation 337
                      regulation of T cell differentiation 182
                        positive regulation of T cell differentiation 106
                          positive regulation of T cell differentiation in thymus + 9
                          positive regulation of alpha-beta T cell differentiation + 55
                          positive regulation of cytotoxic T cell differentiation 2
                          positive regulation of extrathymic T cell differentiation 0
                          positive regulation of gamma-delta T cell differentiation 10
                          positive regulation of memory T cell differentiation 6
                          positive regulation of pro-T cell differentiation 1
                          positive regulation of regulatory T cell differentiation + 25
paths to the root