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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of B cell differentiation
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Accession:GO:0045578 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of B cell differentiation;   downregulation of B cell differentiation;   negative regulation of B lymphocyte differentiation
 narrow_synonym: inhibition of B cell differentiation
 related_synonym: negative regulation of B cell development


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negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) RGD PMID:16618805 NCBI chr12:12,660,035...12,735,584
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) RGD PMID:12714519 NCBI chr  X:154,341,106...154,346,087
Ensembl chr  X:149,296,375...149,301,292 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (PMID:18523151) RGD PMID:18523151 NCBI chr 6:47,469,162...47,470,995
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:18941195)
GO_REF:0000107		 RGD
Ensembl		 PMID:18941195 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158439 (PMID:15240705) RGD PMID:15240705 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    immune system process 3119
      leukocyte activation 1075
        lymphocyte activation 869
          lymphocyte differentiation 449
            B cell differentiation 154
              negative regulation of B cell differentiation 5
                negative regulation of B-1 B cell differentiation 0
                negative regulation of central B cell anergy 0
                negative regulation of central B cell deletion 0
                negative regulation of plasma cell differentiation 1
Path 2
Term Annotations click to browse term
  biological_process 20546
    cellular process 19536
      cellular developmental process 4830
        cell differentiation 4829
          cell development 3350
            hemopoiesis 1083
              leukocyte differentiation 688
                mononuclear cell differentiation 552
                  lymphocyte differentiation 449
                    B cell differentiation 154
                      regulation of B cell differentiation 37
                        negative regulation of B cell differentiation 5
                          negative regulation of B-1 B cell differentiation 0
                          negative regulation of central B cell anergy 0
                          negative regulation of central B cell deletion 0
                          negative regulation of plasma cell differentiation 1
paths to the root