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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of B cell differentiation
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Accession:GO:0045577 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: regulation of B lymphocyte differentiation
 related_synonym: regulation of B cell development


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regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) UniProt PMID:27010503 NCBI chr 2:60,391,110...60,397,559
Ensembl chr 2:60,391,113...60,396,399 		JBrowse link
G CARD11 caspase recruitment domain family member 11 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:2,145,178...2,266,377
Ensembl chr 3:2,145,178...2,266,355 		JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:34,058,091...34,121,939
Ensembl chr 6:34,059,081...34,121,264 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:6610701) MGI PMID:6610701 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G IKZF3 IKAROS family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,466,386...22,562,320
Ensembl chr12:22,466,414...22,562,312 		JBrowse link
G IL4I1 interleukin 4 induced 1 involved_in ISO (PMID:29288206) UniProt PMID:29288206 NCBI chr 6:54,906,401...54,945,840
Ensembl chr 6:54,906,406...54,916,081 		JBrowse link
G LOC100158069 Fc receptor-like protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:92,460,744...92,506,002
Ensembl chr 4:92,460,862...92,504,024 		JBrowse link
G LOC100519934 uncharacterized LOC100519934 acts_upstream_of_or_within ISO (PMID:7795661), (PMID:9028339) MGI PMID:7795661 PMID:9028339 NCBI chr 1:73,119,758...73,124,368 JBrowse link
G MIR150-1 microRNA mir-150-1 acts_upstream_of_or_within ISO (PMID:17927961) MGI PMID:17927961 NCBI chr 6:54,580,912...54,580,988
Ensembl chr 6:54,580,912...54,580,988 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:15143214) InterPro
MGI		 PMID:15143214 GO_REF:0000002 NCBI chr 5:6,296,921...6,333,371
Ensembl chr 5:6,298,573...6,336,730 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:63,762,109...63,779,086
Ensembl chr 5:63,762,112...63,808,350 		JBrowse link
G SLAMF8 SLAM family member 8 involved_in ISO (PMID:11313408) UniProt PMID:11313408 NCBI chr 4:90,661,984...90,673,044
Ensembl chr 4:90,661,985...90,672,572 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:92,490,069...92,495,864
Ensembl chr 7:92,490,017...92,495,554 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:97,200,395...97,203,094
Ensembl chr 3:97,200,407...97,204,698 		JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) MGI PMID:16618805 NCBI chr11:5,370,475...5,455,439
Ensembl chr11:5,370,496...5,455,358 		JBrowse link
G HMGB3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) MGI PMID:12714519 NCBI chr  X:122,591,413...122,599,496
Ensembl chr  X:122,592,936...122,599,493 		JBrowse link
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:125,377,247...125,401,328
Ensembl chr13:125,377,250...125,393,330 		JBrowse link
G CR1 complement C3b/C4b receptor 1 (Knops blood group) acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 9:68,025,673...68,132,162 JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) UniProt PMID:21423173 NCBI chr  X:114,394,436...114,575,658
Ensembl chr  X:114,394,438...114,574,916 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within ISO (PMID:12431371) MGI PMID:12431371 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:64,197,594...64,202,236
Ensembl chr 5:64,196,994...64,202,613 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:57,143,568...57,151,242
Ensembl chr  X:57,143,570...57,147,256 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:57,677,895...57,744,713
Ensembl chr 4:57,684,796...57,744,709 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:133,501,067...133,626,647
Ensembl chr15:133,501,092...133,626,644 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:78,541,278...78,556,784
Ensembl chr11:78,541,318...78,556,733 		JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:64,762,863...64,789,919
Ensembl chr 7:64,763,050...64,789,921 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:15,227,850...15,245,679
Ensembl chr 2:15,227,881...15,245,677 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A involved_in
acts_upstream_of_or_within 		ISS
IEA 		AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,474,221...20,498,785
Ensembl chr12:20,474,227...20,499,138 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within 		ISS
IEA 		AgBase
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:20,498,103...20,574,365
Ensembl chr12:20,508,404...20,574,266 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,670...2,161,171 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G IL10 interleukin 10 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL2 interleukin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 8:101,640,938...101,645,683
Ensembl chr 8:101,640,944...101,645,609 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    immune system process 2590
      leukocyte activation 1061
        lymphocyte activation 872
          lymphocyte differentiation 455
            B cell differentiation 154
              regulation of B cell differentiation 39
                negative regulation of B cell differentiation + 6
                positive regulation of B cell differentiation + 18
                regulation of B-1 B cell differentiation + 0
                regulation of central B cell anergy + 0
                regulation of central B cell deletion + 0
                regulation of plasma cell differentiation + 6
Path 2
Term Annotations click to browse term
  biological_process 18944
    cellular process 18486
      cellular developmental process 4591
        cell differentiation 4590
          cell development 3258
            hemopoiesis 1050
              leukocyte differentiation 677
                mononuclear cell differentiation 550
                  lymphocyte differentiation 455
                    B cell differentiation 154
                      regulation of B cell differentiation 39
                        negative regulation of B cell differentiation + 6
                        positive regulation of B cell differentiation + 18
                        regulation of B-1 B cell differentiation + 0
                        regulation of central B cell anergy + 0
                        regulation of central B cell deletion + 0
                        regulation of plasma cell differentiation + 6
paths to the root