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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of B cell differentiation
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Accession:GO:0045577 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: regulation of B lymphocyte differentiation
 related_synonym: regulation of B cell development


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regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKLE1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) UniProt PMID:27010503 NCBI chr20:45,461,135...45,465,922
Ensembl chr20:45,461,676...45,465,417 		JBrowse link
G CARD11 caspase recruitment domain family member 11 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:14,273,115...14,331,029
Ensembl chr 6:14,210,114...14,332,094 		JBrowse link
G CD24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7795661), (PMID:9028339) MGI PMID:7795661 PMID:9028339 NCBI chr12:64,239,957...64,245,114 JBrowse link
G CYLD CYLD lysine 63 deubiquitinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:64,561,684...64,628,829
Ensembl chr 2:64,562,503...64,628,175 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:6610701) MGI PMID:6610701 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G FCRL3 Fc receptor like 3 involved_in ISO (PMID:23857366) UniProt PMID:23857366 NCBI chr 7:40,599,319...40,625,939 JBrowse link
G IKZF3 IKAROS family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,643,482...22,733,988
Ensembl chr 9:22,643,640...22,728,385 		JBrowse link
G MIR150 microRNA mir-150 acts_upstream_of_or_within ISO (PMID:17927961) MGI PMID:17927961 NCBI chr 1:106,998,756...106,998,812
Ensembl chr 1:106,998,756...106,998,812 		JBrowse link
G NFAM1 NFAT activating protein with ITAM motif 1 involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:15143214) InterPro
MGI		 PMID:15143214 GO_REF:0000002 NCBI chr10:23,008,084...23,047,227
Ensembl chr10:23,008,393...23,045,565 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:38,084,976...38,101,552
Ensembl chr27:38,084,980...38,101,937 		JBrowse link
G SLAMF8 SLAM family member 8 involved_in ISO (PMID:11313408) UniProt PMID:11313408 NCBI chr38:22,299,455...22,307,090
Ensembl chr38:22,300,128...22,307,096 		JBrowse link
G TLR9 toll like receptor 9 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514 		JBrowse link
G ZFP36L2 ZFP36 ring finger protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:45,746,952...45,751,268
Ensembl chr10:45,748,936...45,751,250 		JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FLT3 fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) MGI PMID:16618805 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G HMGB3 high mobility group box 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:119,152,166...119,159,803
Ensembl chr  X:119,155,786...119,159,814 		JBrowse link
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:5,956,924...5,958,833 JBrowse link
G LOC102151783 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:18523151) MGI PMID:18523151 NCBI chr10:54,954,852...54,957,116 JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,262,451...24,306,162
Ensembl chr16:24,261,946...24,302,964 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL6 BCL6 transcription repressor acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr34:20,112,302...20,135,705
Ensembl chr34:20,113,322...20,124,704 		JBrowse link
G LOC490269 complement receptor type 2 acts_upstream_of ISO (PMID:22962438) ARUK-UCL PMID:22962438 NCBI chr 7:6,456,238...6,480,672 JBrowse link
G RTP2 receptor transporter protein 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr34:20,087,395...20,091,248
Ensembl chr34:20,087,226...20,115,428 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP11C ATPase phospholipid transporting 11C involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:109,695,018...109,888,284
Ensembl chr  X:109,697,086...109,880,624 		JBrowse link
G BAD BCL2 associated agonist of cell death acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:52,781,335...52,791,789
Ensembl chr18:52,781,921...52,791,405 		JBrowse link
G CD27 CD27 molecule involved_in IEA InterPro GO_REF:0000002 NCBI chr27:38,534,704...38,537,806
Ensembl chr27:38,534,707...38,537,604 		JBrowse link
G IL2RG interleukin 2 receptor subunit gamma acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr  X:55,480,846...55,488,485
Ensembl chr  X:55,481,092...55,484,751 		JBrowse link
G IL7 interleukin 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr29:26,384,493...26,422,586
Ensembl chr29:26,384,493...26,422,737 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr25:44,612,146...44,731,347
Ensembl chr25:44,611,523...44,730,200 		JBrowse link
G MMP14 matrix metallopeptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:3,183,419...3,193,079
Ensembl chr 8:3,183,606...3,194,122 		JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:805,274...858,901
Ensembl chr27:805,310...843,439 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:60,602,440...60,623,811
Ensembl chr22:60,602,888...60,623,719 		JBrowse link
G PPP2R3C protein phosphatase 2 regulatory subunit B''gamma involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:13,863,017...13,885,245
Ensembl chr 8:13,863,380...13,885,130 		JBrowse link
G SPI1 Spi-1 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,253,849...42,269,497
Ensembl chr18:42,253,811...42,269,727 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:20,616,041...20,638,523
Ensembl chr 9:20,617,151...20,638,103 		JBrowse link
G STAT5B signal transducer and activator of transcription 5B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:20,647,712...20,718,453
Ensembl chr 9:20,691,483...20,716,485 		JBrowse link
G SYK spleen associated tyrosine kinase acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:18,085,865...18,098,868
Ensembl chr24:18,084,725...18,097,157 		JBrowse link
G IL10 interleukin 10 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 7:5,933,285...5,937,057
Ensembl chr 7:5,933,285...5,937,057 		JBrowse link
G IL2 interleukin 2 acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr19:17,750,780...17,756,394
Ensembl chr19:17,750,780...17,756,394 		JBrowse link
G XBP1 X-box binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22130
    immune system process 2648
      leukocyte activation 1055
        lymphocyte activation 859
          lymphocyte differentiation 448
            B cell differentiation 154
              regulation of B cell differentiation 40
                negative regulation of B cell differentiation + 8
                positive regulation of B cell differentiation + 18
                regulation of B-1 B cell differentiation + 0
                regulation of central B cell anergy + 0
                regulation of central B cell deletion + 0
                regulation of plasma cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 22130
    cellular process 21660
      cellular developmental process 4676
        cell differentiation 4675
          cell development 3302
            hemopoiesis 1067
              leukocyte differentiation 679
                mononuclear cell differentiation 550
                  lymphocyte differentiation 448
                    B cell differentiation 154
                      regulation of B cell differentiation 40
                        negative regulation of B cell differentiation + 8
                        positive regulation of B cell differentiation + 18
                        regulation of B-1 B cell differentiation + 0
                        regulation of central B cell anergy + 0
                        regulation of central B cell deletion + 0
                        regulation of plasma cell differentiation + 7
paths to the root