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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of B cell differentiation
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Accession:GO:0045577 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of B cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: regulation of B lymphocyte differentiation
 related_synonym: regulation of B cell development


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regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankle1 ankyrin repeat and LEM domain containing 1 NOT|involved_in ISO (PMID:27010503) RGD PMID:27010503 NCBI chr16:18,076,413...18,082,356
Ensembl chr16:18,076,492...18,083,729 		JBrowse link
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within ISO MGI:3039682 (PMID:12867038) RGD PMID:12867038 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:7795661), (PMID:9028339) RGD PMID:7795661 PMID:9028339 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase acts_upstream_of_or_within ISO MGI:3664438 (PMID:16501569) RGD PMID:16501569 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334 (PMID:6610701) RGD PMID:6610701 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Ikzf3 IKAROS family zinc finger 3 involved_in ISO (PMID:9806640) RGD PMID:9806640 NCBI chr10:83,460,564...83,553,591
Ensembl chr10:83,465,745...83,553,591 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:29288206) RGD PMID:29288206 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Mir150 microRNA 150 acts_upstream_of_or_within ISO MGI:3763431 (PMID:17927961) RGD PMID:17927961 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 acts_upstream_of_or_within ISO (PMID:15143214) RGD PMID:15143214 NCBI chr 7:114,139,318...114,175,395
Ensembl chr 7:114,139,345...114,175,442 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856074 (PMID:9254656)		 Ensembl
RGD		 PMID:9254656 GO_REF:0000107 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Slamf8 SLAM family member 8 involved_in ISO (PMID:11313408) RGD PMID:11313408 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796 		JBrowse link
G Zfp36l1 zinc finger protein 36, C3H type-like 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:27102483)		 UniProt
RGD		 PMID:27102483 GO_REF:0000024 NCBI chr 6:98,930,705...98,935,748
Ensembl chr 6:98,930,718...98,935,748 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 involved_in ISO (PMID:27102483) RGD PMID:27102483 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
negative regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flt3 Fms related receptor tyrosine kinase 3 acts_upstream_of_or_within ISO (PMID:16618805) RGD PMID:16618805 NCBI chr12:7,623,930...7,699,474
Ensembl chr12:7,623,930...7,699,474 		JBrowse link
G Hmgb3 high mobility group box 3 acts_upstream_of_or_within ISO (PMID:12714519) RGD PMID:12714519 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292 		JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134 (PMID:18523151) RGD PMID:18523151 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:18941195)
GO_REF:0000107		 RGD
Ensembl		 PMID:18941195 GO_REF:0000107 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
negative regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158439 (PMID:15240705) RGD PMID:15240705 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) RGD PMID:21423173 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3029528 (PMID:12431371)		 Ensembl
RGD		 PMID:12431371 GO_REF:0000107 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Cd27 CD27 molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO MGI:2429736|MGI:5544783 (PMID:23918385), (PMID:9252128) RGD PMID:9252128 PMID:23918385 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16797412)		 Ensembl
RGD		 PMID:16797412 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:2386884 (PMID:10704460), (PMID:9620849)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:9620849 PMID:10704460 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21572390)		 UniProt
RGD		 PMID:21572390 GO_REF:0000024 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO		 GO_REF:0000024
(PMID:19015308)		 UniProt
RGD		 PMID:19015308 GO_REF:0000024 NCBI chr 7:134,577,470...134,622,928
Ensembl chr 7:134,577,482...134,622,934 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947) RGD PMID:20870947 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
MGI:3759678 (PMID:16129705)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:16129705 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:72,647,025...72,670,885
Ensembl chr 6:72,647,025...72,672,491 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA
ISS		 (PMID:33951726)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:33951726 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (PMID:10979977) RGD PMID:10979977 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103036 (PMID:10979977)		 Ensembl
RGD		 PMID:10979977 GO_REF:0000107 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857421|MGI:2384078 (PMID:7477352), (PMID:7477353)
(PMID:18369315)		 Ensembl
RGD		 PMID:7477352 PMID:7477353 PMID:18369315 GO_REF:0000107 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
ISS		 (PMID:11460154)
GO_REF:0000024		 RGD
UniProt		 PMID:11460154 GO_REF:0000024 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:30842412) RGD PMID:30842412 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO UniProtKB:P22301 (PMID:22962438) RGD PMID:22962438 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
ISS
IEA		 (PMID:11460154)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    immune system process 3112
      leukocyte activation 1069
        lymphocyte activation 866
          lymphocyte differentiation 446
            B cell differentiation 154
              regulation of B cell differentiation 37
                negative regulation of B cell differentiation + 5
                positive regulation of B cell differentiation + 18
                regulation of B-1 B cell differentiation + 0
                regulation of central B cell anergy + 0
                regulation of central B cell deletion + 0
                regulation of plasma cell differentiation + 5
Path 2
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      cellular developmental process 4812
        cell differentiation 4811
          cell development 3339
            hemopoiesis 1079
              leukocyte differentiation 685
                mononuclear cell differentiation 549
                  lymphocyte differentiation 446
                    B cell differentiation 154
                      regulation of B cell differentiation 37
                        negative regulation of B cell differentiation + 5
                        positive regulation of B cell differentiation + 18
                        regulation of B-1 B cell differentiation + 0
                        regulation of central B cell anergy + 0
                        regulation of central B cell deletion + 0
                        regulation of plasma cell differentiation + 5
paths to the root