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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse
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Accession:GO:0045202 term browser browse the term
Definition:The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
Synonyms:exact_synonym: synaptic junction
 narrow_synonym: mixed synapse
 related_synonym: electrotonic synapse
 xref: NIF_Subcellular:sao914572699;   Wikipedia:Chemical_synapse
 only_in_taxon: NCBITaxon:33208 ! Metazoa


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    Path 1
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      cellular_component 21364
        cellular anatomical structure 21069
          cell junction 2605
            synapse 2001
              GABA-ergic synapse + 179
              Schaffer collateral - CA1 synapse 158
              cerebellar Golgi cell to granule cell synapse 2
              cholinergic synapse + 22
              dopaminergic synapse 22
              excitatory synapse + 107
              glutamatergic synapse + 920
              glycinergic synapse 18
              inhibitory synapse + 29
              neuromuscular junction + 110
              neuron to neuron synapse + 555
              noradrenergic synapse 0
              perforant pathway to dendrate granule cell synapse 3
              polyadic synapse 0
              postsynapse + 1058
              presynapse + 896
              ribbon synapse + 34
              serotonergic synapse 3
              synaptic membrane + 586
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