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ONTOLOGY REPORT - ANNOTATIONS

Term:negative thymic T cell selection
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Accession:GO:0045060 term browser browse the term
Definition:The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
Synonyms:exact_synonym: negative thymic T lymphocyte selection


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negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator acts_upstream_of_or_within
involved_in 		IGI
IBA 		(PMID:23382543) MGI
GO_Central		 PMID:23382543 GO_REF:0000033 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within IGI
IMP 		(PMID:23382543) MGI PMID:23382543 NCBI chr10:44,144,325...44,240,295
Ensembl chr10:44,144,354...44,240,287 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in IMP (PMID:17785582) BHF-UCL PMID:17785582 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Cd28 CD28 antigen acts_upstream_of_or_within IMP (PMID:10429671) MGI PMID:10429671 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd3e CD3 antigen, epsilon polypeptide acts_upstream_of_or_within IDA (PMID:7630421) MGI PMID:7630421 NCBI chr 9:44,910,033...44,920,961
Ensembl chr 9:44,910,038...44,920,925 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) acts_upstream_of_or_within IMP (PMID:7679955) MGI PMID:7679955 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Dock2 dedicator of cyto-kinesis 2 acts_upstream_of_or_within IMP (PMID:12871644) MGI PMID:12871644 NCBI chr11:34,176,815...34,674,732
Ensembl chr11:34,176,815...34,674,719 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within IMP (PMID:10429671) MGI PMID:10429671 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 involved_in IMP (PMID:19667090) BHF-UCL PMID:19667090 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Mink1 misshapen-like kinase 1 (zebrafish) acts_upstream_of_or_within IMP (PMID:15608642) MGI PMID:15608642 NCBI chr11:70,452,272...70,505,309
Ensembl chr11:70,453,707...70,505,309 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IMP (PMID:8666928) MGI PMID:8666928 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Shh sonic hedgehog involved_in IMP (PMID:17227833) BHF-UCL PMID:17227833 NCBI chr 5:28,661,838...28,672,099
Ensembl chr 5:28,661,813...28,672,254 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within IMP (PMID:10429671) MGI PMID:10429671 NCBI chr 7:126,731,404...126,743,785
Ensembl chr 7:126,731,404...126,736,995 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase acts_upstream_of_or_within IMP (PMID:7630421) MGI PMID:7630421 NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28626
    immune system process 3186
      T cell selection 66
        negative T cell selection 15
          negative thymic T cell selection 14
Path 2
Term Annotations click to browse term
  biological_process 28626
    cellular process 18393
      cellular developmental process 5187
        cell differentiation 5186
          cell development 3530
            hemopoiesis 1182
              leukocyte differentiation 757
                mononuclear cell differentiation 611
                  lymphocyte differentiation 493
                    T cell differentiation 369
                      T cell selection 66
                        negative T cell selection 15
                          negative thymic T cell selection 14
paths to the root