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ONTOLOGY REPORT - ANNOTATIONS

Term:negative thymic T cell selection
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Accession:GO:0045060 term browser browse the term
Definition:The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
Synonyms:exact_synonym: negative thymic T lymphocyte selection


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negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIRE autoimmune regulator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:30,543,018...30,556,225
Ensembl chr21:43,837,340...43,848,974 		JBrowse link
G ATG5 autophagy related 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:103,997,824...104,140,931
Ensembl chr 6:107,871,208...108,013,807 		JBrowse link
G CCR7 C-C motif chemokine receptor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:16,720,236...16,731,955
Ensembl chr17:16,949,119...16,956,370 		JBrowse link
G CD28 CD28 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2B:90,938,795...90,971,438
Ensembl chr2B:209,076,388...209,111,213 		JBrowse link
G CD74 CD74 molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:145,825,635...145,836,916
Ensembl chr 5:151,830,311...151,841,334 		JBrowse link
G DOCK2 dedicator of cytokinesis 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:165,000,368...165,447,148
Ensembl chr 5:171,778,952...172,206,238 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865 		JBrowse link
G LOC100971372 tyrosine-protein kinase ZAP-70 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr2A:101,582,567...101,613,175
Ensembl chr2A:98,613,740...98,639,088 		JBrowse link
G LOC100978919 T-cell surface glycoprotein CD3 epsilon chain acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:113,142,200...113,153,928
Ensembl chr11:117,074,041...117,085,625 		JBrowse link
G MINK1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chr17:4,879,851...4,944,374
Ensembl chr17:4,868,620...4,932,789 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:174,246,389...174,364,893
Ensembl chr 1:178,556,104...178,672,994 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SPN sialophorin acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 Ensembl chr16:30,035,243...30,036,445 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    immune system process 2524
      T cell selection 61
        negative T cell selection 15
          negative thymic T cell selection 14
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18868
      cellular developmental process 4505
        cell differentiation 4504
          cell development 3203
            hemopoiesis 1032
              leukocyte differentiation 665
                mononuclear cell differentiation 537
                  lymphocyte differentiation 436
                    T cell differentiation 330
                      T cell selection 61
                        negative T cell selection 15
                          negative thymic T cell selection 14
paths to the root