ONTOLOGY REPORT - ANNOTATIONS
Term: T cell selection
Accession: GO:0045058
browse the term
Definition: The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.
Synonyms: exact_synonym: T lymphocyte selection
xref: Wikipedia:Thymocyte
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Cd4
CD4 molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936709:997,776...1,022,791
Ensembl chrNW_004936709:997,750...1,022,884
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LOC101971458
tyrosine-protein kinase ZAP-70
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9275205)
Ensembl MGI
PMID:9275205
GO_REF:0000107
NCBI chrNW_004936744:1,000,105...1,012,712
Ensembl chrNW_004936744:1,000,105...1,012,433
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Rhoa
ras homolog family member A
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936529:1,000,050...1,045,655
Ensembl chrNW_004936529:999,935...1,045,681
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Syk
spleen associated tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9275205)
Ensembl MGI
PMID:9275205
GO_REF:0000107
NCBI chrNW_004936780:1,553,605...1,601,036
Ensembl chrNW_004936780:1,553,605...1,598,158
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Braf
B-Raf proto-oncogene, serine/threonine kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18228248)
Ensembl MGI
PMID:18228248
GO_REF:0000107
NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
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Cyld
CYLD lysine 63 deubiquitinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:16501569)
Ensembl MGI
PMID:16501569
GO_REF:0000107
NCBI chrNW_004936475:3,750,917...3,812,118
Ensembl chrNW_004936475:3,750,882...3,812,118
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Shh
sonic hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599
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Ctsl
cathepsin L
involved_in
ISO
(PMID:9545226)
UniProt
PMID:9545226
NCBI chrNW_004936680:3,047,355...3,050,640
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Tox
thymocyte selection associated high mobility group box
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:13,847,210...14,146,110
Ensembl chrNW_004936496:13,847,210...14,147,886
G
Tox
thymocyte selection associated high mobility group box
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:13,847,210...14,146,110
Ensembl chrNW_004936496:13,847,210...14,147,886
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Bcl2
BCL2 apoptosis regulator
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:8170972)
Ensembl MGI
PMID:8170972
GO_REF:0000107
NCBI chrNW_004936497:2,209,136...2,373,580
Ensembl chrNW_004936497:2,210,334...2,210,921
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Tox
thymocyte selection associated high mobility group box
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:13,847,210...14,146,110
Ensembl chrNW_004936496:13,847,210...14,147,886
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Il15
interleukin 15
acts_upstream_of_or_within
ISO
(PMID:10704459)
MGI
PMID:10704459
NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
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LOC101971454
butyrophilin-like protein 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936727:610,676...617,206
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Ptpn2
protein tyrosine phosphatase non-receptor type 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936626:2,390,004...2,472,039
Ensembl chrNW_004936626:2,389,868...2,445,927
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Jak3
Janus kinase 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936596:3,212,593...3,224,426
Ensembl chrNW_004936596:3,212,593...3,224,048
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Lgals1
galectin 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936492:3,407,704...3,411,197
Ensembl chrNW_004936492:3,407,049...3,411,222
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LOC101954799
signal transducer and activator of transcription 5A
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:17,095,047...17,115,945
Ensembl chrNW_004936490:17,095,954...17,114,866
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Loxl3
lysyl oxidase like 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936556:745,798...765,926
Ensembl chrNW_004936556:745,798...765,918
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Tbx21
T-box transcription factor 21
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635
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Tnfsf18
TNF superfamily member 18
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936481:14,499,495...14,508,074
Ensembl chrNW_004936481:14,499,577...14,508,017
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Themis
thymocyte selection associated
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936639:1,739,380...1,915,545
Ensembl chrNW_004936639:1,739,380...1,915,560
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Aire
autoimmune regulator
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23382543)
Ensembl MGI
PMID:23382543
GO_REF:0000107
NCBI chrNW_004936500:125,589...137,071
Ensembl chrNW_004936500:125,795...137,056
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Atg5
autophagy related 5
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23382543)
Ensembl MGI
PMID:23382543
GO_REF:0000107
NCBI chrNW_004936564:2,759,085...2,885,394
Ensembl chrNW_004936564:2,758,598...2,885,420
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Ccr7
C-C motif chemokine receptor 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:15,575,764...15,579,766
Ensembl chrNW_004936490:15,575,764...15,579,757
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Cd28
CD28 molecule
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:10429671)
Ensembl MGI
PMID:10429671
GO_REF:0000107
NCBI chrNW_004936631:335,411...363,407
Ensembl chrNW_004936631:335,411...363,407
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Cd3e
CD3e molecule
acts_upstream_of_or_within
ISO
(PMID:7630421)
MGI
PMID:7630421
NCBI chrNW_004936542:3,379,361...3,390,677
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Cd74
CD74 molecule
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7679955)
Ensembl MGI
PMID:7679955
GO_REF:0000107
NCBI chrNW_004936504:4,522,576...4,532,289
Ensembl chrNW_004936504:4,522,751...4,531,750
G
Dock2
dedicator of cytokinesis 2
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:12871644)
MGI Ensembl
PMID:12871644
GO_REF:0000107
NCBI chrNW_004936609:4,695,202...5,099,038
Ensembl chrNW_004936609:4,695,628...5,099,038
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Fas
Fas cell surface death receptor
acts_upstream_of_or_within
ISO
(PMID:10429671)
MGI
PMID:10429671
NCBI chrNW_004936735:209,369...234,582
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Gli3
GLI family zinc finger 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936478:17,129,922...17,403,630
Ensembl chrNW_004936478:17,126,911...17,403,011
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LOC101971458
tyrosine-protein kinase ZAP-70
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:7630421)
Ensembl MGI
PMID:7630421
GO_REF:0000107
NCBI chrNW_004936744:1,000,105...1,012,712
Ensembl chrNW_004936744:1,000,105...1,012,433
G
Mink1
misshapen like kinase 1
acts_upstream_of_or_within
ISO
(PMID:15608642)
MGI
PMID:15608642
NCBI chrNW_004936677:2,813,899...2,864,366
Ensembl chrNW_004936677:2,813,899...2,864,366
G
Ptprc
protein tyrosine phosphatase receptor type C
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:8666928)
Ensembl MGI
PMID:8666928
GO_REF:0000107
NCBI chrNW_004936567:5,266,653...5,378,464
Ensembl chrNW_004936567:5,267,615...5,378,258
G
Shh
sonic hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599
G
Spn
sialophorin
acts_upstream_of_or_within
ISO
(PMID:10429671)
MGI
PMID:10429671
NCBI chrNW_004936501:12,773,967...12,776,642
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Brd2
bromodomain containing 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936476:25,807,179...25,818,914
Ensembl chrNW_004936476:25,807,163...25,818,899
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Brd4
bromodomain containing 4
involved_in
ISO
(PMID:28262505)
UniProt
PMID:28262505
NCBI chrNW_004936596:5,176,682...5,246,102
Ensembl chrNW_004936596:5,177,147...5,246,518
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Ep300
E1A binding protein p300
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936492:696,982...778,132
Ensembl chrNW_004936492:696,960...778,138
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Il23a
interleukin 23 subunit alpha
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936646:743,630...745,998
Ensembl chrNW_004936646:743,688...745,836
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Opa1
OPA1 mitochondrial dynamin like GTPase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936711:1,027,531...1,113,796
Ensembl chrNW_004936711:1,032,935...1,106,847
G
Bcl11b
BCL11 transcription factor B
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17998389)
Ensembl MGI
PMID:17998389
GO_REF:0000107
NCBI chrNW_004936604:3,023,781...3,110,104
Ensembl chrNW_004936604:3,023,844...3,110,083
G
Braf
B-Raf proto-oncogene, serine/threonine kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23334952)
Ensembl MGI
PMID:23334952
GO_REF:0000107
NCBI chrNW_004936592:4,728,371...4,833,830
Ensembl chrNW_004936592:4,737,011...4,834,664
G
Themis
thymocyte selection associated
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936639:1,739,380...1,915,545
Ensembl chrNW_004936639:1,739,380...1,915,560
G
Cd3d
CD3d molecule
involved_in
IEA
TreeGrafter Ensembl
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004936542:3,400,129...3,403,628
Ensembl chrNW_004936542:3,399,845...3,403,634
G
Cd74
CD74 molecule
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:9432982) (PMID:7679955), (PMID:8598040)
MGI Ensembl
PMID:7679955 PMID:8598040 PMID:9432982
GO_REF:0000107
NCBI chrNW_004936504:4,522,576...4,532,289
Ensembl chrNW_004936504:4,522,751...4,531,750
G
Dock2
dedicator of cytokinesis 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12871644)
Ensembl MGI
PMID:12871644
GO_REF:0000107
NCBI chrNW_004936609:4,695,202...5,099,038
Ensembl chrNW_004936609:4,695,628...5,099,038
G
Itpkb
inositol-trisphosphate 3-kinase B
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:15064401)
Ensembl MGI
PMID:15064401
GO_REF:0000107
NCBI chrNW_004936526:3,378,046...3,477,177
Ensembl chrNW_004936526:3,376,786...3,477,554
G
LOC101963772
HLA class II histocompatibility antigen, DM alpha chain
acts_upstream_of_or_within
ISO
(PMID:8598040) (PMID:8638109) (PMID:8598041), (PMID:9432982)
MGI
PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982
NCBI chrNW_004936476:25,836,163...25,840,191
Ensembl chrNW_004936476:25,836,142...25,840,197
G
LOC101971458
tyrosine-protein kinase ZAP-70
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:7630421)
MGI Ensembl
PMID:7630421
GO_REF:0000107
NCBI chrNW_004936744:1,000,105...1,012,712
Ensembl chrNW_004936744:1,000,105...1,012,433
G
Nfatc3
nuclear factor of activated T cells 3
involved_in
ISO
(PMID:17579027)
UniProt
PMID:17579027
NCBI chrNW_004936475:18,462,424...18,557,832
Ensembl chrNW_004936475:18,462,298...18,555,220
G
Ptprc
protein tyrosine phosphatase receptor type C
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:8666928)
Ensembl MGI
PMID:8666928
GO_REF:0000107
NCBI chrNW_004936567:5,266,653...5,378,464
Ensembl chrNW_004936567:5,267,615...5,378,258
G
Shh
sonic hedgehog signaling molecule
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936527:10,033,095...10,042,713
Ensembl chrNW_004936527:10,033,299...10,042,599
G
Srf
serum response factor
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:21098124)
Ensembl MGI
PMID:21098124
GO_REF:0000107
NCBI chrNW_004936476:16,779,941...16,789,499
Ensembl chrNW_004936476:16,782,233...16,789,130
G
Stk11
serine/threonine kinase 11
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:21487392)
Ensembl MGI
PMID:21487392
GO_REF:0000107
NCBI chrNW_004936588:579,816...601,033
Ensembl chrNW_004936588:579,816...603,654
G
Foxn1
forkhead box N1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936538:4,717,509...4,745,504
Ensembl chrNW_004936538:4,731,958...4,744,796
G
Tox
thymocyte selection associated high mobility group box
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936496:13,847,210...14,146,110
Ensembl chrNW_004936496:13,847,210...14,147,886
G
Mtor
mechanistic target of rapamycin kinase
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342
G
Spn
sialophorin
involved_in
ISO
(PMID:18036228)
UniProt
PMID:18036228
NCBI chrNW_004936501:12,773,967...12,776,642
G
Stat6
signal transducer and activator of transcription 6
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:20706986)
Ensembl MGI
PMID:20706986
GO_REF:0000107
NCBI chrNW_004936646:1,297,530...1,312,508
Ensembl chrNW_004936646:1,296,290...1,312,157
G
Tbx21
T-box transcription factor 21
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:13,546,405...13,558,635
Ensembl chrNW_004936490:13,546,292...13,558,635
G
Batf
basic leucine zipper ATF-like transcription factor
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936488:4,607,716...4,631,237
Ensembl chrNW_004936488:4,607,716...4,631,283
G
Il6
interleukin 6
involved_in
ISO
(PMID:16990136) (PMID:27893700)
UniProt
PMID:16990136 PMID:27893700
NCBI chrNW_004936549:7,015,595...7,016,246
G
Il6r
interleukin 6 receptor
involved_in
ISO
(PMID:27893700)
UniProt
PMID:27893700
NCBI chrNW_004936580:4,055,438...4,081,876
Ensembl chrNW_004936580:4,057,771...4,081,885
G
Irf4
interferon regulatory factor 4
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936633:1,565,293...1,580,859
Ensembl chrNW_004936633:1,564,637...1,580,859
G
LOC101968708
T-lymphocyte surface antigen Ly-9
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936903:53,648...143,272
Ensembl chrNW_004936903:111,986...143,081
G
Otud5
OTU deubiquitinase 5
acts_upstream_of_or_within
ISO
(PMID:25470037)
MGI
PMID:25470037
NCBI chrNW_004936721:847,360...876,912
Ensembl chrNW_004936721:848,324...877,068
G
Slamf6
SLAM family member 6
involved_in
ISO
(PMID:22184727)
UniProt
PMID:22184727
NCBI chrNW_004936740:155,268...165,536
G
Stat3
signal transducer and activator of transcription 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936490:17,119,189...17,178,402
Ensembl chrNW_004936490:17,117,290...17,178,402
G
Card11
caspase recruitment domain family member 11
acts_upstream_of_or_within
ISO
(PMID:12867038)
MGI
PMID:12867038
NCBI chrNW_004936823:580,438...621,298
Ensembl chrNW_004936823:581,955...621,208
G
Gata3
GATA binding protein 3
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14670303)
Ensembl MGI
PMID:14670303
GO_REF:0000107
NCBI chrNW_004936484:6,780,692...6,800,883
Ensembl chrNW_004936484:6,780,692...6,800,966
G
Itpkb
inositol-trisphosphate 3-kinase B
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14517551)
Ensembl MGI
PMID:14517551
GO_REF:0000107
NCBI chrNW_004936526:3,378,046...3,477,177
Ensembl chrNW_004936526:3,376,786...3,477,554
G
Jag2
jagged canonical Notch ligand 2
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004936621:363,489...380,616
Ensembl chrNW_004936621:366,616...380,618
G
LOC101971458
tyrosine-protein kinase ZAP-70
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9208839)
Ensembl MGI
PMID:9208839
GO_REF:0000107
NCBI chrNW_004936744:1,000,105...1,012,712
Ensembl chrNW_004936744:1,000,105...1,012,433
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all