ONTOLOGY REPORT - ANNOTATIONS
Term: T cell selection
Accession: GO:0045058
browse the term
Definition: The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.
Synonyms: exact_synonym: T lymphocyte selection
xref: Wikipedia:Thymocyte
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Cd4
CD4 molecule
involved_in
ISO
(PMID:9551897)
UniProt
PMID:9551897
NCBI chrNW_004624860:3,470,886...3,492,247
Ensembl chrNW_004624860:3,470,631...3,492,846
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LOC101716577
tyrosine-protein kinase ZAP-70
acts_upstream_of_or_within
ISO
(PMID:9275205)
MGI
PMID:9275205
NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035
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Rhoa
ras homolog family member A
involved_in
ISO
(PMID:25398325)
CACAO
PMID:25398325
NCBI chrNW_004624730:3,316,122...3,361,820
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Syk
spleen associated tyrosine kinase
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:9275205)
Ensembl MGI
PMID:9275205
GO_REF:0000107
NCBI chrNW_004624868:1,654,079...1,738,648
Ensembl chrNW_004624868:1,653,997...1,701,391
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Braf
B-Raf proto-oncogene, serine/threonine kinase
acts_upstream_of_or_within
ISO
(PMID:18228248)
MGI
PMID:18228248
NCBI chrNW_004624765:20,766,368...20,951,560
Ensembl chrNW_004624765:20,773,885...20,951,736
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Cyld
CYLD lysine 63 deubiquitinase
acts_upstream_of_or_within
ISO
(PMID:16501569)
MGI
PMID:16501569
NCBI chrNW_004624757:5,895,912...5,953,485
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Shh
sonic hedgehog signaling molecule
involved_in
ISO
(PMID:17227833)
BHF-UCL
PMID:17227833
NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068
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Tox
thymocyte selection associated high mobility group box
involved_in
ISO
(PMID:18195075)
UniProt
PMID:18195075
NCBI chrNW_004624744:32,865,781...33,218,453
Ensembl chrNW_004624744:32,865,720...33,218,643
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Tox
thymocyte selection associated high mobility group box
involved_in
ISO
(PMID:18195075)
UniProt
PMID:18195075
NCBI chrNW_004624744:32,865,781...33,218,453
Ensembl chrNW_004624744:32,865,720...33,218,643
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Bcl2
BCL2 apoptosis regulator
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:8170972)
MGI Ensembl
PMID:8170972
GO_REF:0000107
NCBI chrNW_004624792:8,854,345...9,032,727
Ensembl chrNW_004624792:8,859,522...9,031,344
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Tox
thymocyte selection associated high mobility group box
involved_in
ISO
(PMID:11850626), (PMID:15078895)
UniProt
PMID:11850626 PMID:15078895
NCBI chrNW_004624744:32,865,781...33,218,453
Ensembl chrNW_004624744:32,865,720...33,218,643
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Il15
interleukin 15
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:10704459)
Ensembl MGI
PMID:10704459
GO_REF:0000107
NCBI chrNW_004624853:1,059,625...1,144,799
Ensembl chrNW_004624853:1,128,519...1,144,941
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Ptpn2
protein tyrosine phosphatase non-receptor type 2
involved_in
ISO
(PMID:22080863)
UniProt
PMID:22080863
NCBI chrNW_004624770:19,808,400...19,877,494
Ensembl chrNW_004624770:19,808,400...19,876,503
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Cd69
CD69 molecule
involved_in
ISO
(PMID:24752896)
UniProt
PMID:24752896
NCBI chrNW_004624860:4,345,497...4,364,251
Ensembl chrNW_004624860:4,345,232...4,365,817
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Jak3
Janus kinase 3
involved_in
ISO
(PMID:20696842)
UniProt
PMID:20696842
NCBI chrNW_004624908:1,371,595...1,383,879
Ensembl chrNW_004624908:1,371,595...1,383,879
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Lgals1
galectin 1
involved_in
ISO
(PMID:24752896)
UniProt
PMID:24752896
NCBI chrNW_004624752:10,220,115...10,223,434
Ensembl chrNW_004624752:10,219,872...10,223,317
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Loxl3
lysyl oxidase like 3
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624749:28,959,682...28,980,428
Ensembl chrNW_004624749:28,960,593...28,980,428
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Tbx21
T-box transcription factor 21
involved_in
ISO
(PMID:21151104)
UniProt
PMID:21151104
NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
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Tnfsf18
TNF superfamily member 18
involved_in
ISO
(PMID:24107315)
UniProt
PMID:24107315
NCBI chrNW_004624771:8,711,093...8,722,518
Ensembl chrNW_004624771:8,711,017...8,722,539
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Themis
thymocyte selection associated
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624753:2,214,779...2,292,936
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Aire
autoimmune regulator
acts_upstream_of_or_within
ISO
(PMID:23382543)
MGI
PMID:23382543
NCBI chrNW_004624745:29,850,410...29,857,351
Ensembl chrNW_004624745:29,850,560...29,857,029
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Atg5
autophagy related 5
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:23382543)
Ensembl MGI
PMID:23382543
GO_REF:0000107
NCBI chrNW_004624780:15,987,483...16,124,158
Ensembl chrNW_004624780:15,987,397...16,124,151
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Ccr7
C-C motif chemokine receptor 7
involved_in
ISO
(PMID:17785582)
BHF-UCL
PMID:17785582
NCBI chrNW_004624795:2,777,766...2,787,664
Ensembl chrNW_004624795:2,779,627...2,788,897
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Cd28
CD28 molecule
acts_upstream_of_or_within
ISO
(PMID:10429671)
MGI
PMID:10429671
NCBI chrNW_004624765:12,650,092...12,667,168
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Cd3e
CD3e molecule
acts_upstream_of_or_within
ISO
(PMID:7630421)
MGI
PMID:7630421
NCBI chrNW_004624784:13,714,667...13,726,881
Ensembl chrNW_004624784:13,712,920...13,726,950
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Cd74
CD74 molecule
acts_upstream_of_or_within
ISO
(PMID:7679955)
MGI
PMID:7679955
NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514
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Dock2
dedicator of cytokinesis 2
acts_upstream_of_or_within
ISO
(PMID:12871644)
MGI
PMID:12871644
NCBI chrNW_004624733:19,882,234...20,315,211
Ensembl chrNW_004624733:19,883,027...20,315,128
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Fas
Fas cell surface death receptor
acts_upstream_of_or_within
ISO
(PMID:10429671)
MGI
PMID:10429671
NCBI chrNW_004624791:15,290,022...15,315,848
Ensembl chrNW_004624791:15,289,348...15,315,848
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Gli3
GLI family zinc finger 3
involved_in
ISO
(PMID:19667090)
BHF-UCL
PMID:19667090
NCBI chrNW_004624740:18,961,395...19,238,760
Ensembl chrNW_004624740:18,975,596...19,235,900
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LOC101716577
tyrosine-protein kinase ZAP-70
acts_upstream_of_or_within
ISO
(PMID:7630421)
MGI
PMID:7630421
NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035
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Mink1
misshapen like kinase 1
acts_upstream_of_or_within
ISO
(PMID:15608642)
MGI
PMID:15608642
NCBI chrNW_004624786:8,711,388...8,764,102
Ensembl chrNW_004624786:8,711,263...8,763,343
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Ptprc
protein tyrosine phosphatase receptor type C
acts_upstream_of_or_within
ISO
(PMID:8666928)
MGI
PMID:8666928
NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
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Shh
sonic hedgehog signaling molecule
involved_in
ISO
(PMID:17227833)
BHF-UCL
PMID:17227833
NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068
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Spn
sialophorin
acts_upstream_of_or_within
ISO
(PMID:10429671)
MGI
PMID:10429671
NCBI chrNW_004624782:13,471,083...13,483,712
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Brd2
bromodomain containing 2
involved_in
ISO
(PMID:28262505)
UniProt
PMID:28262505
NCBI chrNW_004624754:23,742,506...23,750,668
Ensembl chrNW_004624754:23,742,509...23,750,062
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Brd4
bromodomain containing 4
involved_in
ISO
(PMID:28262505)
UniProt
PMID:28262505
NCBI chrNW_004624901:2,348,218...2,434,429
Ensembl chrNW_004624901:2,346,734...2,380,852
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Il23a
interleukin 23 subunit alpha
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chrNW_004624802:11,662,851...11,664,444
Ensembl chrNW_004624802:11,662,753...11,665,418
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Opa1
OPA1 mitochondrial dynamin like GTPase
involved_in
ISO
(PMID:36171294)
UniProt
PMID:36171294
NCBI chrNW_004624730:63,911,066...63,994,886
Ensembl chrNW_004624730:63,911,066...63,995,596
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Bcl11b
BCL11 transcription factor B
acts_upstream_of_or_within
ISO
(PMID:17998389)
MGI
PMID:17998389
NCBI chrNW_004624734:4,560,362...4,649,219
Ensembl chrNW_004624734:4,560,699...4,647,858
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Braf
B-Raf proto-oncogene, serine/threonine kinase
acts_upstream_of_or_within
ISO
(PMID:23334952)
MGI
PMID:23334952
NCBI chrNW_004624765:20,766,368...20,951,560
Ensembl chrNW_004624765:20,773,885...20,951,736
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Themis
thymocyte selection associated
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624753:2,214,779...2,292,936
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Cd3d
CD3d molecule
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624784:13,733,465...13,754,248
Ensembl chrNW_004624784:13,733,403...13,737,356
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Cd3e
CD3e molecule
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624784:13,714,667...13,726,881
Ensembl chrNW_004624784:13,712,920...13,726,950
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Cd3g
CD3g molecule
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624784:13,738,424...13,748,311
Ensembl chrNW_004624784:13,738,686...13,748,415
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Cd74
CD74 molecule
acts_upstream_of_or_within
ISO
(PMID:9432982) (PMID:7679955), (PMID:8598040)
MGI
PMID:7679955 PMID:8598040 PMID:9432982
NCBI chrNW_004624774:9,699,876...9,708,871
Ensembl chrNW_004624774:9,700,393...9,709,514
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Dock2
dedicator of cytokinesis 2
acts_upstream_of_or_within
ISO
(PMID:12871644)
MGI
PMID:12871644
NCBI chrNW_004624733:19,882,234...20,315,211
Ensembl chrNW_004624733:19,883,027...20,315,128
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Itpkb
inositol-trisphosphate 3-kinase B
acts_upstream_of_or_within
ISO
(PMID:15064401)
MGI
PMID:15064401
NCBI chrNW_004624807:658,334...741,018
Ensembl chrNW_004624807:658,231...741,195
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LOC101700274
HLA class II histocompatibility antigen, DM alpha chain
acts_upstream_of_or_within
ISO
(PMID:8638109) (PMID:8598041), (PMID:9432982) (PMID:8598040)
MGI
PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982
NCBI chrNW_004624754:23,752,352...23,765,319
Ensembl chrNW_004624754:23,762,051...23,765,593
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LOC101716577
tyrosine-protein kinase ZAP-70
acts_upstream_of_or_within
ISO
(PMID:7630421)
MGI
PMID:7630421
NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035
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Nfatc3
nuclear factor of activated T cells 3
involved_in
ISO
(PMID:17579027)
UniProt
PMID:17579027
NCBI chrNW_004624746:18,083,051...18,210,399
Ensembl chrNW_004624746:18,085,518...18,210,401
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Ptprc
protein tyrosine phosphatase receptor type C
acts_upstream_of_or_within
ISO
(PMID:8666928)
MGI
PMID:8666928
NCBI chrNW_004624798:1,700,732...1,814,603
Ensembl chrNW_004624798:1,699,541...1,814,656
G
Shh
sonic hedgehog signaling molecule
involved_in
ISO
(PMID:17227833)
BHF-UCL
PMID:17227833
NCBI chrNW_004624800:2,202,986...2,215,309
Ensembl chrNW_004624800:2,203,393...2,212,068
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Srf
serum response factor
acts_upstream_of_or_within
ISO
(PMID:21098124)
MGI
PMID:21098124
NCBI chrNW_004624754:16,371,995...16,381,287
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Stk11
serine/threonine kinase 11
acts_upstream_of_or_within
ISO
(PMID:21487392)
MGI
PMID:21487392
NCBI chrNW_004624828:7,444,339...7,466,926
Ensembl chrNW_004624828:7,445,069...7,467,298
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Foxn1
forkhead box N1
involved_in
ISO
(PMID:24184560)
UniProt
PMID:24184560
NCBI chrNW_004624786:1,114,305...1,127,787
Ensembl chrNW_004624786:1,114,305...1,127,683
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Tox
thymocyte selection associated high mobility group box
involved_in
ISO
(PMID:18195075)
UniProt
PMID:18195075
NCBI chrNW_004624744:32,865,781...33,218,453
Ensembl chrNW_004624744:32,865,720...33,218,643
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Il4
interleukin 4
acts_upstream_of_or_within
ISO
(PMID:20706986)
MGI
PMID:20706986
NCBI chrNW_004624733:39,412,800...39,420,079
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Mtor
mechanistic target of rapamycin kinase
involved_in
ISO
(PMID:26410627)
MGI
PMID:26410627
NCBI chrNW_004624818:1,570,155...1,698,264
Ensembl chrNW_004624818:1,570,276...1,698,259
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Spn
sialophorin
involved_in
ISO
(PMID:18036228)
UniProt
PMID:18036228
NCBI chrNW_004624782:13,471,083...13,483,712
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Stat6
signal transducer and activator of transcription 6
acts_upstream_of_or_within
ISO
(PMID:20706986)
MGI
PMID:20706986
NCBI chrNW_004624802:10,809,234...10,847,762
Ensembl chrNW_004624802:10,809,252...10,846,693
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Tbx21
T-box transcription factor 21
involved_in
ISO
(PMID:10761931)
UniProt
PMID:10761931
NCBI chrNW_004624795:4,442,188...4,453,544
Ensembl chrNW_004624795:4,442,188...4,453,143
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Batf
basic leucine zipper ATF-like transcription factor
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chrNW_004624734:26,118,840...26,139,328
Ensembl chrNW_004624734:26,118,754...26,139,468
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Il6
interleukin 6
involved_in
ISO
(PMID:27893700) (PMID:16990136)
UniProt
PMID:16990136 PMID:27893700
NCBI chrNW_004624739:7,957,709...7,963,414
Ensembl chrNW_004624739:7,957,674...7,962,318
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Il6r
interleukin 6 receptor
involved_in
ISO
(PMID:27893700)
UniProt
PMID:27893700
NCBI chrNW_004624885:2,910,367...2,946,916
Ensembl chrNW_004624885:2,910,112...2,946,886
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Irf4
interferon regulatory factor 4
involved_in
ISO
(PMID:22983707)
UniProt
PMID:22983707
NCBI chrNW_004624756:23,917,111...23,931,482
Ensembl chrNW_004624756:23,918,323...23,931,501
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Otud5
OTU deubiquitinase 5
acts_upstream_of_or_within
ISO
(PMID:25470037)
MGI
PMID:25470037
NCBI chrNW_004624893:702,895...736,623
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Slamf6
SLAM family member 6
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624794:754,530...796,732
G
Stat3
signal transducer and activator of transcription 3
involved_in
ISO
(PMID:28065600)
UniProt
PMID:28065600
NCBI chrNW_004624795:1,648,235...1,680,788
Ensembl chrNW_004624795:1,648,080...1,681,200
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Card11
caspase recruitment domain family member 11
acts_upstream_of_or_within
ISO
(PMID:12867038)
MGI
PMID:12867038
NCBI chrNW_004624740:29,974,707...30,085,498
Ensembl chrNW_004624740:29,974,689...30,085,981
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Gata3
GATA binding protein 3
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:14670303)
Ensembl MGI
PMID:14670303
GO_REF:0000107
NCBI chrNW_004624775:2,985,077...3,014,567
Ensembl chrNW_004624775:2,994,164...3,015,392
G
Itpkb
inositol-trisphosphate 3-kinase B
acts_upstream_of_or_within
ISO
(PMID:14517551)
MGI
PMID:14517551
NCBI chrNW_004624807:658,334...741,018
Ensembl chrNW_004624807:658,231...741,195
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Jag2
jagged canonical Notch ligand 2
involved_in
ISO
(PMID:10383933)
UniProt
PMID:10383933
NCBI chrNW_004624734:308,371...327,496
Ensembl chrNW_004624734:308,375...327,604
G
LOC101716577
tyrosine-protein kinase ZAP-70
acts_upstream_of_or_within
ISO
(PMID:9208839)
MGI
PMID:9208839
NCBI chrNW_004624749:2,893,601...2,901,256
Ensembl chrNW_004624749:2,893,601...2,901,035
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all