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ONTOLOGY REPORT - ANNOTATIONS

Term:nuclear pore central transport channel
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Accession:GO:0044613 term browser browse the term
Definition:The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
Synonyms:exact_synonym: nuclear pore central channel;   nuclear pore central plug;   nuclear pore transport channel
 related_synonym: karyopherin docking complex


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nuclear pore central transport channel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07018058.1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr15:35,707,571...35,707,954 JBrowse link
G Nup35 nucleoporin 35 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:85,965,907...85,991,659
Ensembl chr 3:85,945,080...85,992,027 		JBrowse link
G Nup54 nucleoporin 54 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:15,901,936...15,920,335
Ensembl chr14:15,901,991...15,920,334 		JBrowse link
G Nup62 nucleoporin 62 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:104,435,532...104,451,392
Ensembl chr 1:104,432,093...104,452,710 		JBrowse link
G Nup62cl nucleoporin 62 C-terminal like part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:108,457,043...108,513,525
Ensembl chr  X:108,457,043...108,512,664 		JBrowse link
G Nutf2 nuclear transport factor 2 part_of IDA
IBA 		GO_REF:0000033 GO_Central
RGD		 PMID:10543952 GO_REF:0000033, RGD:9831376 NCBI chr19:50,662,168...50,683,457
Ensembl chr19:50,662,394...50,683,454 		JBrowse link
G Nxt1 nuclear transport factor 2-like export factor 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:156,562,121...156,565,043
Ensembl chr 3:156,560,556...156,565,996 		JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:110,652,434...110,659,738
Ensembl chr  X:110,652,434...110,659,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19485
    protein-containing complex 6265
      nuclear protein-containing complex 1368
        nuclear pore central transport channel 8
Path 2
Term Annotations click to browse term
  cellular_component 19485
    cellular anatomical structure 19353
      organelle 13686
        membrane-bounded organelle 12471
          intracellular membrane-bounded organelle 11899
            nucleus 7471
              nuclear protein-containing complex 1368
                nuclear pore 81
                  nuclear pore central transport channel 8
paths to the root