Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of digestive system process
go back to main search page
Accession:GO:0044058 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


show annotations for term's descendants           Sort by:
negative regulation of defecation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crhr2 corticotropin releasing hormone receptor 2 IMP RGD PMID:21277852 RGD:5491003 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IMP RGD PMID:21708257 RGD:9831204 NCBI chr 8:30,882,830...31,107,425
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO MGI:3723512 (PMID:17030183) RGD PMID:17030183 NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267 		JBrowse link
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
G Ptger3 prostaglandin E receptor 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Tff2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2179101 (PMID:11805131)		 GO_Central
RGD		 PMID:11805131 GO_REF:0000033 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nmu neuromedin U involved_in IDA PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192 		JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:15961884 RGD:10043339 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Sct secretin involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11123201 GO_REF:0000033, RGD:9590235 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 IMP RGD PMID:23333829 RGD:11099975 NCBI chr 4:89,006,056...89,132,915
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in ISO
IEA		 (PMID:12469120)
GO_REF:0000107		 RGD
Ensembl		 PMID:12469120 GO_REF:0000107 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Isx intestine-specific homeobox acts_upstream_of_or_within ISO MGI:3703167 (PMID:25701869) RGD PMID:25701869 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:15,717,936...15,743,376
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 involved_in ISO (PMID:11099417) RGD PMID:11099417 NCBI chr 6:15,698,448...15,717,730
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in ISO
IEA		 (PMID:18806227)
GO_REF:0000107		 RGD
Ensembl		 PMID:18806227 GO_REF:0000107 NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (PMID:21317537) RGD PMID:21317537 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:21317537)		 Ensembl
RGD		 PMID:21317537 GO_REF:0000107 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (PMID:21317537) RGD PMID:21317537 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (PMID:21317537) RGD PMID:21317537 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurog1 neurogenin 1 involved_in ISO UniProtKB:Q6ZNK6|UniProtKB:Q8TF63 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,362,878...8,364,397
Ensembl chr17:8,362,821...8,364,571 		JBrowse link
G Tifab TIFA inhibitor involved_in ISO UniProtKB:Q8TF63|UniProtKB:Q92886 (PMID:23419067) RGD PMID:23419067 NCBI chr17:8,433,406...8,436,541
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
positive regulation of digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA gut paracellular permeability RGD PMID:17234701 RGD:5491013 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:19258489 RGD:2304084 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IDA RGD PMID:14724155 RGD:9835340 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acat2 acetyl-CoA acetyltransferase 2 involved_in ISO (PMID:22045928) RGD PMID:22045928 NCBI chr 1:50,100,840...50,118,886
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (PMID:12393855) RGD PMID:12393855 NCBI chr 8:130,455,622...130,457,592
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24650549)		 UniProt
RGD		 PMID:24650549 GO_REF:0000024 NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26833026)		 UniProt
RGD		 PMID:26833026 GO_REF:0000024 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
positive regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a5 solute carrier family 22 member 5 involved_in ISO (PMID:18005709) RGD PMID:18005709 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
positive regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prap1 proline-rich acidic protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:33168624)		 UniProt
RGD		 PMID:33168624 GO_REF:0000024 NCBI chr 1:194,883,078...194,886,874
Ensembl chr 1:194,883,078...194,886,872 		JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npr3 natriuretic peptide receptor 3 IMP RGD PMID:12829435 RGD:1581460 NCBI chr 2:62,592,557...62,660,497
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18806227)		 Ensembl
RGD		 PMID:18806227 GO_REF:0000107 NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Sct secretin involved_in IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:11123201 GO_REF:0000033, RGD:9590235 NCBI chr 1:205,812,435...205,813,246
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:2755938 RGD:10044250 NCBI chr18:36,121,626...36,133,596
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
positive regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15727941), (PMID:9096382)		 UniProt
RGD		 PMID:9096382 PMID:15727941 GO_REF:0000024 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Negr1 neuronal growth regulator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:4451714 (PMID:37216094)
GO_REF:0000107		 RGD
Ensembl		 PMID:37216094 GO_REF:0000107 NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:21435446)		 UniProt
RGD		 PMID:21435446 GO_REF:0000024 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Tac4 tachykinin precursor 4 acts_upstream_of_or_within ISO (PMID:11062498) RGD PMID:11062498 NCBI chr10:80,704,640...80,712,972
Ensembl chr10:80,207,610...80,216,156 		JBrowse link
positive regulation of small intestinal transit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:21874246 RGD:12910732 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:21874246 PMID:15890336 RGD:12910732, RGD:12907565 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hip1r huntingtin interacting protein 1 related involved_in ISO (PMID:18535670) RGD PMID:18535670 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:16314573), (PMID:19491250)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16314573 PMID:19491250 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669 		JBrowse link
regulation of gastric motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrl ghrelin and obestatin prepropeptide IDA RGD PMID:23525979 RGD:12907567 NCBI chr 4:148,421,315...148,431,128
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:23525979 RGD:12907567 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Tymp thymidine phosphorylase involved_in ISO (PMID:9924029) RGD PMID:9924029 NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghsr growth hormone secretagogue receptor IMP RGD PMID:16873401 RGD:1625276 NCBI chr 2:112,196,158...112,201,666
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A IMP RGD PMID:22049154 RGD:8657330 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Epb41 erythrocyte membrane protein band 4.1 involved_in ISO (PMID:23460639) RGD PMID:23460639 NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821 		JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 acts_upstream_of_or_within ISO (PMID:10073953) RGD PMID:10073953 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa2 apolipoprotein A2 acts_upstream_of_or_within ISO MGI:2157148 (PMID:8962133) RGD PMID:8962133 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2157162 (PMID:9323588)		 Ensembl
RGD		 PMID:9323588 GO_REF:0000107 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Lep leptin acts_upstream_of_or_within ISO (PMID:12114517) RGD PMID:12114517 NCBI chr 4:58,626,529...58,640,663
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
regulation of intestinal D-glucose absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn15 claudin 15 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20727355), (PMID:23089202)		 UniProt
RGD		 PMID:20727355 PMID:23089202 GO_REF:0000024 NCBI chr12:25,334,849...25,345,104
Ensembl chr12:19,698,337...19,706,819 		JBrowse link
G Cldn2 claudin 2 involved_in ISO (PMID:23089202) RGD PMID:23089202 NCBI chr  X:108,248,383...108,258,847
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Neurod1 neuronal differentiation 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9512516)		 UniProt
RGD		 PMID:9512516 GO_REF:0000024 NCBI chr 3:84,766,483...84,770,454
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cldn15 claudin 15 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23089202)		 UniProt
RGD		 PMID:23089202 GO_REF:0000024 NCBI chr12:25,334,849...25,345,104
Ensembl chr12:19,698,337...19,706,819 		JBrowse link
G Cldn2 claudin 2 involved_in ISO (PMID:23089202) RGD PMID:23089202 NCBI chr  X:108,248,383...108,258,847
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 IMP RGD PMID:18768481 RGD:10400848 NCBI chr 7:110,104,514...110,119,091
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21177474)		 UniProt
RGD		 PMID:21177474 GO_REF:0000024 NCBI chr10:104,740,763...104,745,760
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 involved_in ISO (PMID:19102732) RGD PMID:19102732 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Oprk1 opioid receptor, kappa 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9463367)		 UniProt
RGD		 PMID:9463367 GO_REF:0000024 NCBI chr 5:18,657,866...18,675,671
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    multicellular organismal process 9001
      system process 3568
        digestive system process 126
          regulation of digestive system process 52
            negative regulation of digestive system process + 19
            positive regulation of digestive system process + 19
            regulation of defecation + 2
            regulation of gastric acid secretion + 7
            regulation of gastric motility + 4
            regulation of hindgut contraction + 3
            regulation of intestinal absorption + 19
            regulation of intestinal epithelial structure maintenance + 2
            regulation of pancreatic juice secretion + 9
            regulation of saliva secretion + 8
            regulation of small intestinal transit + 2
Path 2
Term Annotations click to browse term
  biological_process 20546
    biological regulation 13834
      regulation of biological process 13389
        regulation of multicellular organismal process 3344
          regulation of system process 683
            regulation of digestive system process 52
              negative regulation of digestive system process + 19
              positive regulation of digestive system process + 19
              regulation of defecation + 2
              regulation of gastric acid secretion + 7
              regulation of gastric motility + 4
              regulation of hindgut contraction + 3
              regulation of intestinal absorption + 19
              regulation of intestinal epithelial structure maintenance + 2
              regulation of pancreatic juice secretion + 9
              regulation of saliva secretion + 8
              regulation of small intestinal transit + 2
paths to the root