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ONTOLOGY REPORT - ANNOTATIONS

Term:inositol phosphate metabolic process
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Accession:GO:0043647 term browser browse the term
Definition:The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms:exact_synonym: inositol phosphate metabolism
 narrow_synonym: myo-inositol phosphate metabolic process;   myo-inositol phosphate metabolism
 xref: Reactome:R-HSA-1483249 "Inositol phosphate metabolism"


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inositol phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galr2 galanin receptor 2 IDA RGD PMID:9427506 RGD:69840 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176 		JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IMP RGD PMID:17573483 RGD:5685371 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP RGD PMID:1331748 RGD:9727450 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in ISO (PMID:8999861) RGD PMID:8999861 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428 		JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in ISO
IEA
ISS		 (PMID:30624931)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:30624931 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Plek pleckstrin involved_in ISO (PMID:8999861) RGD PMID:8999861 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
diphosphoinositol polyphosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt3 nudix hydrolase 3 involved_in ISO
IEA
ISS		 (PMID:10585413)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:10585413 GO_REF:0000024 GO_REF:0000107 NCBI chr20:5,634,345...5,686,950
Ensembl chr20:5,634,349...5,686,874 		JBrowse link
diphosphoinositol polyphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt3 nudix hydrolase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:5,634,345...5,686,950
Ensembl chr20:5,634,349...5,686,874 		JBrowse link
G Nudt4 nudix hydrolase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615 		JBrowse link
inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ip6k1 inositol hexakisphosphate kinase 1 involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:5635272 (PMID:24657168)
GO_REF:0000107		 InterPro
GO_Central
RGD
Ensembl		 PMID:24657168 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166 		JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:11502751)
GO_REF:0000002
GO_REF:0000107
GO_REF:0000033		 RGD
InterPro
Ensembl
GO_Central		 PMID:11502751 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428 		JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 GO_REF:0000002
GO_REF:0000033
MGI:3583918 (PMID:15939867)		 InterPro
GO_Central
RGD		 PMID:15939867 GO_REF:0000002 GO_REF:0000033 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705 		JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541 		JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000002		 GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779 		JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428 		JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:98,315,220...98,394,537
Ensembl chr 9:98,315,252...98,390,814 		JBrowse link
inositol phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15707678 RGD:9743914 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Pten phosphatase and tensin homolog IDA RGD PMID:18056380 RGD:2292524 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Synj2 synaptojanin 2 IDA RGD PMID:9388224 RGD:69390 NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687 		JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Plcg2 phospholipase C, gamma 2 acts_upstream_of_or_within ISO (PMID:9013981) RGD PMID:9013981 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of ISO MGI:1856024|MGI:1856025 (PMID:11371619) RGD PMID:11371619 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Ptafr platelet-activating factor receptor acts_upstream_of_or_within ISO (PMID:9013981) RGD PMID:9013981 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
inositol trisphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inppl1 inositol polyphosphate phosphatase-like 1 IDA RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500 		JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in ISO (PMID:30624931) RGD PMID:30624931 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705 		JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:1654894)		 UniProt
Ensembl
RGD		 PMID:1654894 GO_REF:0000024 GO_REF:0000107 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Plcb1 phospholipase C beta 1 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 3:142,512,765...143,224,042
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plcb3 phospholipase C beta 3 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228 		JBrowse link
G Plcg1 phospholipase C, gamma 1 IDA RGD PMID:7812955 RGD:151356942 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO
IEA		 (PMID:7782310)
GO_REF:0000107		 RGD
Ensembl		 PMID:7782310 GO_REF:0000107 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:237,818,950...239,052,184
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8396727 PMID:8943280 RGD:631732, RGD:2315982 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B involved_in ISO
IEA		 (PMID:9322919)
GO_REF:0000107		 RGD
Ensembl		 PMID:9322919 GO_REF:0000107 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Cd244 CD244 molecule involved_in ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11861328 RGD:9743897 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Pth parathyroid hormone involved_in ISO
IEA		 (PMID:11604398)
GO_REF:0000107		 RGD
Ensembl		 PMID:11604398 GO_REF:0000107 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pth1r parathyroid hormone 1 receptor involved_in IDA PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729 		JBrowse link
G Snca synuclein alpha involved_in ISO
IEA		 (PMID:15641770)
GO_REF:0000107		 RGD
Ensembl		 PMID:15641770 GO_REF:0000107 NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15705806)		 UniProt
RGD		 PMID:15705806 GO_REF:0000024 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:10493819)		 Ensembl
RGD		 PMID:10493819 GO_REF:0000107 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:111,224,291...111,304,963
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024|MGI:1856025 (PMID:11371619) RGD PMID:11371619 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb1 arrestin, beta 1 IMP RGD PMID:20705669 RGD:5509896 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:20705669 RGD:5509896 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Ntsr1 neurotensin receptor 1 IDA RGD PMID:12869647 RGD:596992334 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        phosphorus metabolic process 2299
          phosphate-containing compound metabolic process 2296
            inositol phosphate metabolic process 45
              diphosphoinositol polyphosphate metabolic process + 2
              inositol phosphate biosynthetic process + 33
              inositol phosphate catabolic process + 4
              inositol trisphosphate metabolic process + 20
              myo-inositol hexakisphosphate metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        small molecule metabolic process 1928
          alcohol metabolic process 401
            polyol metabolic process 119
              inositol phosphate metabolic process 45
                diphosphoinositol polyphosphate metabolic process + 2
                inositol phosphate biosynthetic process + 33
                inositol phosphate catabolic process + 4
                inositol trisphosphate metabolic process + 20
                myo-inositol hexakisphosphate metabolic process + 0
paths to the root